On a leafy suburban street in Dublin, beautiful, poised Stella Greene lives with her successful husband, Matt. They're the perfect couple in every way, and Stella appears to have it all. Next door, at number 72, however, lives Rea Brady. Gruff, bad tempered and rarely seen besides the twitching of her net curtains, rumour has it she's lost it all...including her marbles, if you believe the neighbourhood gossip. But appearances can be deceiving, and when Stella and Rea's worlds collide they realise they have much in common.

Adam adores Emily. Emily thinks Adam’s perfect, the man she thought she’d never meet. Emily chose Adam, but she didn’t choose his mother, Pammie. There’s nothing a mother wouldn’t do for her son, and now Emily is about to find out just how far Pammie will go to get what she wants: Emily gone forever.

At the age of 22, Jennifer Worth left her comfortable home to move into a convent and become a midwife in postwar London’s East End slums. The colorful characters she met while delivering babies all over London - from the plucky, warm-hearted nuns with whom she lived to the woman with 24 children who couldn't speak English to the prostitutes and dockers of the city’s seedier side - illuminate a fascinating time in history.

In 1918, after four harrowing years on the Western Front, Tom Sherbourne returns to Australia to take a job as the lighthouse keeper on remote Janus Rock. To this isolated island, where the supply boat comes only four times a year and shore leaves are granted every other year at best, Tom brings a young, bold, and loving wife, Isabel. Three years later, after two miscarriages and one stillbirth, the grieving Isabel is tending the grave of her newly lost infant when she hears a baby’s cries on the wind. A boat has washed up on shore carrying a dead man and a living baby.

Born on a farm outside Edinburgh in the mid-19th century, Agnes Watt is embraced by family, community, and tradition. Her youthful hopes and dreams are quashed but she falls in love and marries William Miller, a Gordon Highlander. Life spirals into dark places as the couple become ensnared in the nightmare that descended on the Scottish working class during the industrial revolution. The triumphs of the great Victorian era came at an appalling human cost and Agnes fights against disease and grinding poverty.

When Cissy Ryan’s real mother comes to claim her from the workhouse, it’s not how she imagined. Her family’s tumbledown cottage has ice on the inside of its windows and is in an isolated, poverty-stricken village in the muddy Irish countryside. But when Cissy is allowed to help neighbour Colm Doyle and his horse named Blue on their milk round one morning, Cissy starts to feel as though friendship could get her through anything.

Born in rural Palestine, just before the dawn of the 20th century, Miriam adores her father and is certain his love will protect her, but she soon finds that tradition overrides love. Uprooted by war, Miriam enters a world where the old constraints slip away with thrilling and disastrous results. Miriam's rebellious daughter, Nadia, is thrilled with the opportunity for a modern life that her elite education provides. But when she falls in love with an outsider, the clan reins her back with a shocking finality.

Susie did something that she knows she will always regret: giving her baby son up for adoption, to keep her infidelity secret from her family. Louise, Susie's daughter, feels the effects of that decision echoing down through the years - her mother has always been difficult, too strict with her but not strict enough with her sister, Grace, who is wild and out of control. And Danny, Susie's husband, adores her but has always sensed something wrong at the heart of their marriage.

In the autumn of 1940, four children meet on a train. Behind them is London, under heavy aerial attack; ahead of them is a ship bound for the safe shores of Canada. Arthur has promised his mother not to let his little brother, Philip, out of his sight. Pippa and Dora are on their own: polar opposites, brought together by the adventure of a lifetime. But disaster strikes mid-Atlantic, and in the chaos one of the children makes a choice that will determine the course of their lives forever.

London 1940. As the war rages in Europe, Rose Brown steps on board a ship bound for America, hoping to escape the danger. She's frightened, but her widowed mammy and three sisters in Ireland need the money she earns as nanny to the rich Townsend family. But while Rose plays with baby Sarah in the salty spray on deck, disaster strikes, and the ocean liner begins to sink. In the chaos, Rose and the baby are separated from the family.

East London, 1888 - a city apart. A place of shadow and light where thieves, whores, and dreamers mingle, where children play in the cobbled streets by day and a killer stalks at night, where bright hopes meet the darkest truths. Here, by the whispering waters of the Thames, Fiona Finnegan, a worker in a tea factory, hopes to own a shop one day, together with her lifelong love, Joe Bristow, a costermonger's son. With nothing but their faith in each other to spur them on, Fiona and Joe struggle, save, and sacrifice to achieve their dreams.

London, 1942: Thirteen-year-old Nell and five-year-old Olive are being sent away from home to escape the devastation of the East End during the Blitz. Leaving behind their beloved mother and brothers, they don’t know if they will ever see them again. As the sisters adjust to their new life in a close-knit Welsh village, they gradually find hope in the friendships they make. And Nell kindles a special bond with fellow evacuee Jimmy, who makes her smile even at the hardest of times. But when little Olive’s safety is threatened, Nell makes a decision that will change their lives forever.

As Britain stands alone against a monstrous enemy, the inhabitants of Pearl Street face hardship and heartbreak with courage and humour. The war touches each of them in a different way: for Annie Poulson, a widow, it means never-ending worry when her twin boys are called up and sent to France; Sheila Reilly's husband, Cal, faces the terror of U-Boat attacks; Eileen Costello is liberated from a bitter, loveless marriage when her husband is sent to Egypt.

Young and desperately in love, Merrin had the whole world ahead of her. But just as her new life was about to start, the ground beneath her feet was cruelly swept away. Devastated by the humiliation, she ran far away from the beloved fishing village she had always called home to lick her wounds and escape her gossiping friends and neighbors. It hasn’t been easy, but six years later Merrin has forged a new life for herself far from the sea, burying the impulsive girl she once was.

Dottie and Mary forged a friendship over a bag of penny sweets when they were eight years old. They've shared everything together since then. Now, at seventeen, they're both shopgirls working at Woolworths. As they go out in the world in pursuit of love and happiness and life becomes more complicated, the simplicity of their childhood dissolves. The heady excitement of first love will consume them both, but the pain of unintentional betrayal will test their friendship.

When Cissy Ryan’s real mother comes to claim her from the workhouse, it’s not how she imagined. Her family’s tumbledown cottage has ice on the inside of its windows and is in an isolated, poverty-stricken village in the muddy Irish countryside. But when Cissy is allowed to help neighbour Colm Doyle and his horse named Blue on their milk round one morning, Cissy starts to feel as though friendship could get her through anything.

On a leafy suburban street in Dublin, beautiful, poised Stella Greene lives with her successful husband, Matt. They're the perfect couple in every way, and Stella appears to have it all. Next door, at number 72, however, lives Rea Brady. Gruff, bad tempered and rarely seen besides the twitching of her net curtains, rumour has it she's lost it all...including her marbles, if you believe the neighbourhood gossip. But appearances can be deceiving, and when Stella and Rea's worlds collide they realise they have much in common.

East London, 1888 - a city apart. A place of shadow and light where thieves, whores, and dreamers mingle, where children play in the cobbled streets by day and a killer stalks at night, where bright hopes meet the darkest truths. Here, by the whispering waters of the Thames, Fiona Finnegan, a worker in a tea factory, hopes to own a shop one day, together with her lifelong love, Joe Bristow, a costermonger's son. With nothing but their faith in each other to spur them on, Fiona and Joe struggle, save, and sacrifice to achieve their dreams.

As Britain stands alone against a monstrous enemy, the inhabitants of Pearl Street face hardship and heartbreak with courage and humour. The war touches each of them in a different way: for Annie Poulson, a widow, it means never-ending worry when her twin boys are called up and sent to France; Sheila Reilly's husband, Cal, faces the terror of U-Boat attacks; Eileen Costello is liberated from a bitter, loveless marriage when her husband is sent to Egypt.

Mary Doyle arrives in Dublin in 1913, doomed, she fears, to a life of domestic service. Instead, however, she finds herself deeply affected by the social and political turmoil of a fledgling nation struggling for independence. Suddenly, all that was once inevitable is no longer a certainty as she is embroiled in the very heart of the Easter Rising.

Three very different girls sign up as trainee nurses at a big London teaching hospital in 1934. Dora leaves her overcrowded, squalid working-class home for a better life. But has she got what it takes to keep up with other, better-educated girls? And will her hated stepfather ever let her go? Helen is born for the job; her brother is a doctor, her all-powerful mother a hospital trustee. But will Helen’s secret misery be her downfall? An aristocratic rebel, Millie’s carefree attitude will find her up in front of Matron again and again. Will she ever care enough to make a nurse? Or will she go back to the glamorous life she was born to?

Liverpool, 1941. Troubled by a dark family history and the pain of seeing her country torn apart by war, young June Lavender finds new hope when she takes a job at the Dr Barnardo's children's home. There she meets Lizzie McRae, a little girl who is the spitting image of June's sister, who died tragically years before. Against the matron's wishes, the two girls form an unexpected bond as June tries to get the traumatised orphan to speak.

Welcome to the district nurses' home on Steeple Street, where everyone has a secret.... Ambitious young nurse Agnes Sheridan had a promising future ahead of her until a tragic mistake cost her the love and respect of everyone around her. Now she has come to Leeds for a fresh start as a trainee district nurse. But Agnes finds herself facing unexpected challenges as she is assigned to Quarry Hill, one of the city's most notorious slums.

Alice Lake has arrived in London from Liverpool to start her training as a District Nurse, but her journey has been far from easy. Her parents think that she should settle down and get married, but she has already had her heart broken once and isn’t about to make the same mistake again. Alice and her best friend, Edith, are based in the East End, but before they’ve even got their smart new uniforms on, war breaks out, and Hitler’s bombs are raining down on London.

2002, Australia. When Melissa discovers a postcard addressed to 'Desmond' among her recently deceased father's effects, she is determined to discover this person's identity and his relationship to her father. She soon embarks on a journey that will take her across oceans and into the past...

Liverpool, 1940. When her childhood sweetheart, Johnny, is killed in action, Maxine Grey loses more than her husband - she loses her best friend. Desperate to make a difference in this awful war, Maxine takes a nursing job at London’s St Thomas’ hospital. She takes comfort in the attentions of a handsome surgeon, but Edwin Blake isn’t all he seems. And as the Blitz descends on the capital, Maxine faces more heartache. When she returns to Liverpool, she harbours a secret.

Rose Grahame had everything Alex D’Arcy dreams of. A handsome husband, a stunning home and a baby boy with twinkling blue eyes and a smile that would brighten the darkest of days. It’s a stark contrast to Alex’s life - her dead-end job, her borderline addiction to drink and pills, her failed engagement and her cluttered flat. But the women’s lives are about to collide - and nothing will ever be the same again.

When a mysterious note arrives for six months pregnant Dr Eliana Hughes, she begins to doubt every aspect of her life - from her mixed feelings about motherhood to her marriage to Martin, who has become distant in recent months. As the person behind the note escalates their campaign to out Eli’s husband as a cheat, she finds herself unable to trust even her own instincts, and as pressure builds, she makes a mistake that jeopardises her entire future. Elsewhere, someone is watching.

At the age of 22, Jennifer Worth left her comfortable home to move into a convent and become a midwife in postwar London’s East End slums. The colorful characters she met while delivering babies all over London - from the plucky, warm-hearted nuns with whom she lived to the woman with 24 children who couldn't speak English to the prostitutes and dockers of the city’s seedier side - illuminate a fascinating time in history.

When sixteen-year-old Sally is evacuated to the English south coast, she is terrified by what lies ahead of her. All she knows are the sights and sounds of London's East End – but Sally swallows her tears as they leave the familiar landmarks behind, knowing that she has to be a Grown-Up Girl and play mother to her six-year-old brother Ernie. Playing mother is nothing new for Sally – their real mother Florrie, a good-time girl, hasn't even come to the station to wave them off and Ernie, crippled at an early age by polio, is used to depending on his older sister.