Dr. Margo Dunlop is at a crossroads. Her adoptive mom just passed away, and Margo misses her so much she can't begin to empty the house - or, it seems, get her brother on the phone. Not to mention she's newly single, secretly pregnant, and worried about her best friend's dangerous relationship. In an effort to cheer herself up she goes in search of her birth mother. Instead she finds Nikki, her mother's sister. Aunt Nikki isn't what Margo expects, and she brings upsetting news: Margo's mother is dead.

For Susan Green, messy emotions don’t fit into the equation of her perfectly ordered life. She has a flat that is ideal for one, a job that suits her passion for logic, and an “interpersonal arrangement” that provides cultural and other more intimate benefits. But suddenly confronted with the loss of her mother and the news that she is about to become a mother herself, Susan’s greatest fear is realized. She is losing control.

High-powered businesswoman Lana Rubicon has a lot to be proud of: her keen intelligence, impeccable taste, and the L.A. real estate empire she’s built. But when she finds herself trapped 300 miles north of the city, convalescing in a sleepy coastal town with her adult daughter Beth and teenage granddaughter Jack, Lana is stuck counting otters instead of square footage—and hoping that boredom won’t kill her before the cancer does.

Celebrating her forty-fifth birthday at her local pub, popular podcaster Alix Summer crosses paths with an unassuming woman called Josie Fair. Josie, it turns out, is also celebrating her forty-fifth birthday. They are, in fact, birthday twins. A few days later, Alix and Josie bump into each other again, this time outside Alix’s children’s school. Josie has been listening to Alix’s podcasts and thinks she might be an interesting subject for her series. She is, she tells Alix, on the cusp of great changes in her life.

Sloane, Ardie, Grace, and Rosalita have worked at Truviv, Inc., for years. The sudden death of Truviv’s CEO means their boss, Ames, will likely take over the entire company. Each of the women has a different relationship with Ames, who has always been surrounded by whispers about how he treats women. Those whispers have been ignored, swept under the rug, hidden away by those in charge. But the world has changed, and the women are watching this promotion differently.

It is midnight on the morning of Halloween, and Jen anxiously waits up for her 18-year-old son, Todd, to return home. But worries about his broken curfew transform into something much more dangerous when Todd finally emerges from the darkness. As Jen watches through the window, she sees her funny, seemingly happy teenage son stab a total stranger.

Alix Chamberlain is a woman who gets what she wants and has made a living, with her confidence-driven brand, showing other women how to do the same. So she is shocked when her babysitter, Emira Tucker, is confronted while watching the Chamberlains' toddler one night, walking the aisles of their local high-end supermarket. The store's security guard, seeing a young Black woman out late with a White child, accuses Emira of kidnapping two-year-old Briar. A small crowd gathers, a bystander films everything, and Emira is furious and humiliated. Alix resolves to make things right.

Chemist Elizabeth Zott is not your average woman. In fact, Elizabeth Zott would be the first to point out that there is no such thing as an average woman. But it’s the early 1960s and her all-male team at Hastings Research Institute takes a very unscientific view of equality. Except for one: Calvin Evans; the lonely, brilliant, Nobel–prize nominated grudge-holder who falls in love with—of all things—her mind. True chemistry results.

Littleport, Maine, has always felt like two separate towns: an ideal vacation enclave for the wealthy, whose summer homes line the coastline, and a simple harbor community for the year-round residents whose livelihoods rely on service to the visitors. Typically, fierce friendships never develop between a local and a summer girl - but that’s just what happens with visitor Avery Greer and Littleport resident Sadie Loman. Each summer for almost a decade, the girls are inseparable - until Sadie is found dead.

Adam adores Emily. Emily thinks Adam’s perfect, the man she thought she’d never meet. Emily chose Adam, but she didn’t choose his mother, Pammie. There’s nothing a mother wouldn’t do for her son, and now Emily is about to find out just how far Pammie will go to get what she wants: Emily gone forever.

At the height of the Cold War, two secretaries are pulled out of the typing pool at the CIA and given the assignment of a lifetime. Their mission: to smuggle Doctor Zhivago out of the USSR, where no one dare publish it, and help Pasternak's magnum opus make its way into print around the world. Glamorous and sophisticated Sally Forrester is a seasoned spy who has honed her gift for deceit all over the world - using her magnetism and charm to pry secrets out of powerful men. Irina is a complete novice, and is under Sally's tutelage....

Emmeline lives on a remote island with her father, who teaches her about the natural world through her senses. What he won’t explain are the mysterious scents stored in glass bottles that line the walls of their cabin, or the origin of the machine that creates them. As Emmeline grows, however, so too does her curiosity, until one day the unforeseen happens, and Emmeline is vaulted out into the real world—a place of love, betrayal, ambition, and revenge. To understand her past, Emmeline must unlock the clues to her identity.

Emily is having the time of her life - she’s in the mountains of Chile with her best friend, Kristen, on their annual reunion trip, and the women are feeling closer than ever. But on the last night of the trip, Emily enters their hotel suite to find blood and broken glass on the floor. Kristen says the cute backpacker she brought back to their room attacked her, and she had no choice but to kill him in self-defense.

Widower Jack Harris has resisted the dating scene ever since the shooting of his wife Molly by a fifteen-year-old boy three years ago. An early morning run along the Hudson River changes that when he spots a woman in last night’s party dress, barefoot, enjoying a champagne picnic alone, reading his favorite novel. Everything about her reminds him of what he used to have with Molly. Eager to help Jack find love again, his best friend posts a message on a popular website after he mentions the encounter.

In these eight powerful, emotionally absorbing stories, a romance unexpectedly sparks between two wounded friends; a marriage ends for what seem like noble reasons, but with irreparable consequences; a young woman holds on to an impossible dream even as she fights for her survival; two lovers reunite after unimaginable tragedy, both for their country and in their lives; a baby's christening brings three generations of a family to a precarious dance between old and new; a man falls to his death in slow motion, reliving the defining moments of the life he is about to lose.