From the story of the desperate man from 17th-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers a wealth of fascinating and unforgettable insights into medicine and history via the operating room. What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell, or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?

Written by an author with plenty of experience holding a scalpel, Dr. David Schneider's in-depth biography is an encompassing history of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing implant revolution of the 20th century.

Today, astonishing surgical breakthroughs are making limb transplants, face transplants, and a host of other previously undreamed-of operations possible. But getting here has not been a simple story of medical progress. In Blood and Guts, veteran science writer Richard Hollingham weaves a compelling narrative from the key moments in surgical history. We have a ringside seat in the operating theater of University College Hospital in London as world-renowned Victorian surgeon Robert Liston performs a remarkable amputation in 30 seconds - from first cut to final stitch.

The Great War of 1914-1918 burst on the European scene with a brutality to mankind not yet witnessed by the civilized world. Modern warfare was no longer the stuff of chivalry and honor; it was a mutilative, deadly, and humbling exercise to wipe out the very presence of humanity. Suddenly, thousands upon thousands of maimed, beaten, and bleeding men surged into aid stations and hospitals with injuries unimaginable in their scope and destruction. Doctors scrambled to find some way to salvage not only life but limb.

In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.

From the moment the first machine gun rang out over the Western Front, one thing was clear: mankind’s military technology had wildly surpassed its medical capabilities. Bodies were battered, gouged, hacked, and gassed. The First World War claimed millions of lives and left millions more wounded and disfigured. In the midst of this brutality, however, there were also those who strove to alleviate suffering. The Facemaker tells the extraordinary story of such an individual: the pioneering plastic surgeon Harold Gillies.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

Dr. Jonathan Reisman - a physician, adventure traveler, and naturalist - brings listeners on an odyssey, navigating our insides like an explorer discovering a new world. With unique insight, Reisman shows us how understanding mountain watersheds helps to diagnose heart attacks, how the body is made mostly of mucus, not water, and how urine carries within it a tale of humanity’s origins.

The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".

We think of transplant surgery as one of the medical wonders of the modern world. But transplant surgery is as ancient as the pyramids, with a history more surprising than we might expect. Paul Craddock takes us on a journey—from sixteenth-century skin grafting to contemporary stem cell transplants—uncovering stories of operations performed by unexpected people in unexpected places. Bringing together philosophy, science and cultural history, Spare Parts explores how transplant surgery constantly tested the boundaries between human, animal, and machine.

In The Knife Man, Wendy Moore unveils John Hunter's murky and macabre world - a world characterized by public hangings, secret expeditions to dank churchyards, and gruesome human dissections in pungent attic rooms. This is a fascinating portrait of a remarkable pioneer and his determined struggle to haul surgery out of the realms of meaningless superstitious ritual and into the dawn of modern medicine.

Tumors, injuries, ruptured vascular malformations—there is almost no such thing as a non-urgent brain surgery when it comes to kids. For a pediatric neurosurgeon working in the medical minefield of the brain—in which a single millimeter in every direction governs something that makes us essentially human—every day presents the challenge, and the opportunity, to give a new lease on life to a child for whom nothing is yet fully determined and all possibilities still exist.

By turns heartbreaking, hilarious, and utterly human, The House of God is a mesmerizing and provocative journey that takes us into the lives of Roy Basch and five of his fellow interns at the most renowned teaching hospital in the country.

When Michael Collins decided to become a surgeon, he was totally unprepared for the chaotic life of a resident at a major hospital. A natural overachiever, Collins' success in college and medical school led to a surgical residency at one of the most respected medical centers in the world, the famed Mayo Clinic. But compared to his fellow residents, Collins felt inadequate and unprepared.

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells - taken without her knowledge - became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than 60 years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects.

In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.

Praised for his erudite writing, renowned scientist Frank Gonzalez-Crussi penned this concise history of medicine, beginning with the most primitive health-care practices and ending with the technology of modern medicine that we enjoy today. As with all Modern Library Chronicles, A Short History of Medicine is a wonderful primer for anyone interested in the subject.

At one time heart disease was a death sentence. By the middle of the 20th century, it was killing millions, and, as with the Black Death centuries before, physicians stood helpless. Visionaries, though, had begun to make strides earlier. On September 7, 1895, Ludwig Rehn successfully sutured the heart of a living man with a knife wound to the chest for the first time.

Written by an author with plenty of experience holding a scalpel, Dr. David Schneider's in-depth biography is an encompassing history of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing implant revolution of the 20th century.

The Great War of 1914-1918 burst on the European scene with a brutality to mankind not yet witnessed by the civilized world. Modern warfare was no longer the stuff of chivalry and honor; it was a mutilative, deadly, and humbling exercise to wipe out the very presence of humanity. Suddenly, thousands upon thousands of maimed, beaten, and bleeding men surged into aid stations and hospitals with injuries unimaginable in their scope and destruction. Doctors scrambled to find some way to salvage not only life but limb.

Happy Accidents is a fascinating, entertaining, and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the 20th century. What do penicillin, chemotherapy drugs, X-rays, Valium, the Pap smear, and Viagra have in common? They were each discovered accidentally, stumbled upon in the search for something else. In discussing medical breakthroughs, Dr. Morton Meyers makes a cogent, highly engaging argument for a more creative, rather than purely linear, approach to science. And it may just save our lives!

David Oshinsky, whose last book, Polio: An American Story, was awarded a Pulitzer Prize, chronicles the history of America's oldest hospital and in so doing also charts the rise of New York to the nation's preeminent city, the path of American medicine from butchery and quackery to a professional and scientific endeavor, and the growth of a civic institution.

In the winter of 1918, at the height of World War I, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 weeks than AIDS has killed in 24 years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision between modern science and epidemic disease.

On average, a physician will interrupt a patient describing her symptoms within 12 seconds. In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong: with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make.

From the story of the desperate man from 17th-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers a wealth of fascinating and unforgettable insights into medicine and history via the operating room. What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell, or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?

For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As cardiologist and best-selling author Sandeep Jauhar tells in The Heart, it was only recently that we demolished age-old taboos and devised the transformative procedures that changed the way we live. Deftly alternating between historical episodes and his own work, Jauhar tells the colorful and little known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ.

The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic medication. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.

This comprehensive and gripping narrative, which received the 2006 Pulitzer Prize for history, covers all the challenges, characters, and controversies in America's relentless struggle against polio. Funded by philanthropy and grassroots contributions, Salk's killed-virus vaccine (1954) and Sabin's live-virus vaccine (1961) began to eradicate this dreaded disease.

Important and provocative, The Undead examines why even with the tools of advanced technology, what we think of as life and death, consciousness and nonconsciousness, is not exactly clear - and how this problem has been further complicated by the business of organ harvesting.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

Written by an author with plenty of experience holding a scalpel, Dr. David Schneider's in-depth biography is an encompassing history of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing implant revolution of the 20th century.

From the story of the desperate man from 17th-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers a wealth of fascinating and unforgettable insights into medicine and history via the operating room. What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell, or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?

Now published in five languages, Strange Medicine casts a gimlet eye on the practice of medicine through the ages that highlights the most dubious ideas, bizarre treatments, and biggest blunders. From bad science and oafish behavior to stomach-turning procedures that hurt more than helped, Strange Medicine presents strange but true facts and an honor roll of doctors, scientists, and dreamers who inadvertently turned the clock of medicine backward.

Science is a force for good in the world—at least usually. But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn’t everything, it’s the only thing—no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process.

From the moment the first machine gun rang out over the Western Front, one thing was clear: mankind’s military technology had wildly surpassed its medical capabilities. Bodies were battered, gouged, hacked, and gassed. The First World War claimed millions of lives and left millions more wounded and disfigured. In the midst of this brutality, however, there were also those who strove to alleviate suffering. The Facemaker tells the extraordinary story of such an individual: the pioneering plastic surgeon Harold Gillies.

Imagine undergoing an operation without anesthesia performed by a surgeon who refuses to sterilize his tools - or even wash his hands. This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the 19th century. Although he died at just 48, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.

The Great War of 1914-1918 burst on the European scene with a brutality to mankind not yet witnessed by the civilized world. Modern warfare was no longer the stuff of chivalry and honor; it was a mutilative, deadly, and humbling exercise to wipe out the very presence of humanity. Suddenly, thousands upon thousands of maimed, beaten, and bleeding men surged into aid stations and hospitals with injuries unimaginable in their scope and destruction. Doctors scrambled to find some way to salvage not only life but limb.

A puzzling series of dental explosions beginning in the 19th century is just one of many strange tales that have long lain undiscovered in the pages of old medical journals. Award-winning medical historian Thomas Morris delivers one of the most remarkable, cringe-inducing collections of stories ever assembled.

Today, astonishing surgical breakthroughs are making limb transplants, face transplants, and a host of other previously undreamed-of operations possible. But getting here has not been a simple story of medical progress. In Blood and Guts, veteran science writer Richard Hollingham weaves a compelling narrative from the key moments in surgical history. We have a ringside seat in the operating theater of University College Hospital in London as world-renowned Victorian surgeon Robert Liston performs a remarkable amputation in 30 seconds - from first cut to final stitch.

Madame Restell is a sharp, witty Gilded Age medical history which introduces us to an iconic, yet tragically overlooked, feminist heroine: a glamorous women’s healthcare provider in Manhattan, known to the world as Madame Restell. A celebrity in her day with a flair for high fashion and public, petty beefs, Restell was a self-made woman and single mother who used her wit, her compassion, and her knowledge of family medicine to become one of the most in-demand medical workers in New York.