
Gray Matters
A Biography of Brain Surgery
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Narrated by:
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Sean Pratt
An Economist Best Book of 2024
“If you are at all curious about the brain or the surgeons who operate on it, Gray Matters is a must read and Dr. Theodore Schwartz is the perfect guide, a master brain surgeon and superbly talented writer. I have not read a better biography of our shared profession, and in Schwartz's talented hands, the most enigmatic 3 1/2 pounds of tissue in the known universe comes to light in remarkable and revelatory ways.”—Dr. Sanjay Gupta, CNN Chief Medical Correspondent, and New York Times and #1 Wall Street Journal bestselling author of Keep Sharp: Build a Better Brain at Any Age
A popular biography of brain surgery, by one of its preeminent practitioners
We’ve all heard the phrase “it’s not brain surgery.” But what exactly is brain surgery? It’s a profession that is barely a hundred years old and profoundly connects two human beings, but few know how it works, or its history. How did early neurosurgeons come to understand the human brain—an extraordinarily complex organ that controls everything we do, and yet at only three pounds is so fragile? And how did this incredibly challenging and lifesaving specialty emerge?
In this warm, rigorous, and deeply insightful book, Dr. Theodore H. Schwartz explores what it’s like to hold the scalpel, wield the drill, extract a tumor, fix a bullet hole, and remove a blood clot—when every second can mean life or death. Drawing from the author’s own cases, plus media, sports, and government archives, this seminal work delves into all the brain-related topics that have long-consumed public curiosity, like what really happened to JFK, President Biden’s brain surgery, and the NFL’s management of CTE. Dr. Schwartz also surveys the field’s latest incredible advances and discusses the philosophical questions of the unity of the self and the existence of free will.
A neurosurgeon as well as a professor of neurosurgery at Weill Cornell Medicine, one of the busiest and most highly ranked neurosurgery centers in the world, Dr. Schwartz tells this story like no one else could. Told through anecdote and clear explanation, this is the ultimate cultural and scientific history of a literally mind-blowing human endeavor, one that cuts to the core of who we are.
©2024 Theodore H. Schwartz (P)2024 Penguin AudioListeners also enjoyed...




















Critic reviews
“A fascinating glimpse behind the curtain…. Dr. Schwartz has spent his career using his hands to make brains healthier. Now, he uses the power of stories to shed light on the mysteries of the mind.”—The Wall Street Journal
“Neurosurgeon Schwartz’s excellent debut intersperses details about the history of brain surgery with background on what it’s like to perform the procedure…Sweeping and consistently captivating, this impresses.”—Publishers Weekly (starred)
"An informative study of modern brain surgery. . . . Mixing expertise with storytelling, Schwartz provides a remarkable account of a crucial but misunderstood field.”—Kirkus (starred)
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The neurosurgical residency can be very rigorous. I laughed out loud when I read about a resident who spent 100 days in the hospital without coming home. His wife left him but returned when overcome with guilt. When he finally came home he thought everything was fine as he had not known that his wife had left.
As a physician, I enjoy my successes but my negative outcomes stay with me for life. Dr. Schwartz shares those feelings.
I particularly enjoyed the topic of whether free will is an illusion.
My favorite physician author was Dr. Abraham Verghese but now it is Dr. Schwartz. By reading his book, I can tell that he is skilled, on the cutting edge, yet prudent. Also, his empathy comes through in his writing. If I ever need brain surgery, I will seek him out.
Gary Matsumura, MD
Gripping storytelling
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Wrong about Kennedy
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Lessons of the heart from a brain surgeon
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Fascinating
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Ralph J Argen MD FACP FACR
The reading and the product
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Fabulous....
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Amazing
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Warpspeed historybof Neurosurgery, from stone age to Computer Brain Interfaces, brilliant and engrossing
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What stood out the most was the story was relatable.
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Outstanding -
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