Knowledge is a big subject, says Stuart Firestein, but ignorance is a bigger one. And it is ignorance - not knowledge - that is the true engine of science. Most of us have a false impression of science as a surefire, deliberate, step-by-step method for finding things out and getting things done. In fact, says Firestein, more often than not, science is like looking for a black cat in a dark room, and there may not be a cat in the room.

Robert Sapolsky’s Behave, his now classic account of why humans do good and why they do bad, pointed toward an unsettling conclusion: We may not grasp the precise marriage of nature and nurture that creates the physics and chemistry at the base of human behavior, but that doesn’t mean it doesn’t exist. Now, in Determined, Sapolsky takes his argument all the way, mounting a brilliant (and in his inimitable way, delightful) full-frontal assault on the pleasant fantasy that there is some separate self telling our biology what to do.

We live in a world that’s obsessed with talent. We celebrate gifted students in school, natural athletes in sports, and child prodigies in music. But admiring people who start out with innate advantages leads us to overlook the distance we ourselves can travel. We underestimate the range of skills that we can learn and how good we can become. We can all improve at improving. And when opportunity doesn’t knock, there are ways to build a door.

Achievement often comes at a cost. Angst, restlessness, frayed relationships, exhaustion, and even substance abuse can be the unwanted side effects of an obsession with outward performance. While the high of occasional wins can keep you going for a while, playing into the always-on, never enough hustle culture ultimately takes a serious toll.

This audiobook is about luck, or more precisely, how we perceive and deal with luck in life and business. It is already a landmark work, and its title has entered our vocabulary. In its second edition, Fooled by Randomness is now a cornerstone for anyone interested in random outcomes.

In this pathbreaking book, Jonathan Rauch reaches back to the parallel 18th-century developments of liberal democracy and science to explain what he calls the “Constitution of Knowledge” - our social system for turning disagreement into truth. By explicating the Constitution of Knowledge and probing the war on reality, Rauch arms defenders of truth with a clearer understanding of what they must protect, why they must do - and how they can do it.

A bold and all-embracing exploration of the nature and progress of knowledge from one of today's great thinkers. Throughout history, mankind has struggled to understand life's mysteries, from the mundane to the seemingly miraculous. In this important new book, David Deutsch, an award-winning pioneer in the field of quantum computation, argues that explanations have a fundamental place in the universe.

The science of emotion is in the midst of a revolution on par with the discovery of relativity in physics and natural selection in biology. Leading the charge is psychologist and neuroscientist Lisa Feldman Barrett, whose research overturns the long-standing belief that emotions are automatic, universal, and hardwired in different brain regions. Instead, Barrett shows, we construct each instance of emotion through a unique interplay of brain, body, and culture.

Drawing on cutting-edge neuroscience, behavioral economic, and social psychology research, acclaimed author, former Harvard professor, and think tank founder Todd Rose reveals how so much of our thinking about each other is informed by false assumptions that drive bad decisions that make us dangerously mistrustful as a society and hopelessly unhappy as individuals.

When it comes to what we believe, humans see what they want to see. In other words, we have what Julia Galef calls a "soldier" mindset. From tribalism and wishful thinking, to rationalizing in our personal lives and everything in between, we are driven to defend the ideas we most want to believe - and shoot down those we don't.

Dr. Francis Collins, head of the Human Genome Project, is one of the world's leading scientists, yet he is also a man of unshakable faith in God and scripture. Dr. Collins has resolved the dilemma that haunts everyone who believes in God and respects science. Faith in God and faith in science can be harmonious, not separately but together, combined into one worldview. For Collins, science does not conflict with the Bible, science enhances it.

Ellenberg chases mathematical threads through a vast range of time and space, from the everyday to the cosmic, encountering, among other things, baseball, Reaganomics, daring lottery schemes, Voltaire, the replicability crisis in psychology, Italian Renaissance painting, artificial languages, the development of non-Euclidean geometry, the coming obesity apocalypse, Antonin Scalia's views on crime and punishment, the psychology of slime molds, what Facebook can and can't figure out about you, and the existence of God.

The Skeptics' Guide to the Universe is your map through this maze of modern life. Here Dr. Steven Novella and friends will explain the tenets of skeptical thinking and debunk some of the biggest scientific myths, fallacies, and conspiracy theories - from anti-vaccines to homeopathy, UFO sightings to N-rays. You'll learn the difference between science and pseudoscience, essential critical thinking skills, ways to discuss conspiracy theories with that crazy co-worker of yours, and how to combat sloppy reasoning, bad arguments, and superstitious thinking.

"Correlation does not imply causation". This mantra has been invoked by scientists for decades and has led to a virtual prohibition on causal talk. But today, that taboo is dead. The causal revolution, sparked by Judea Pearl and his colleagues, has cut through a century of confusion and placed causality - the study of cause and effect - on a firm scientific basis.

The Great Mental Models: General Thinking Concepts is the first book in The Great Mental Models series designed to upgrade your thinking with the best, most useful and powerful tools so you always have the right one on hand. This volume details nine of the most versatile all-purpose mental models you can use right away to improve your decision making, your productivity, and how clearly you see the world.

American taxpayers spend $30 billion annually funding biomedical research, but over half of these studies can't be replicated due to poor experimental design, improper methods, and sloppy statistics. Bad science doesn't just hold back medical progress, it can sign the equivalent of a death sentence for terminal patients. In Rigor Mortis, Richard Harris explores these urgent issues with vivid anecdotes, personal stories, and interviews with the top biomedical researchers. We need to fix our dysfunctional biomedical system - before it's too late.

"Correlation does not imply causation". This mantra has been invoked by scientists for decades and has led to a virtual prohibition on causal talk. But today, that taboo is dead. The causal revolution, sparked by Judea Pearl and his colleagues, has cut through a century of confusion and placed causality - the study of cause and effect - on a firm scientific basis.

The Great Mental Models: General Thinking Concepts is the first book in The Great Mental Models series designed to upgrade your thinking with the best, most useful and powerful tools so you always have the right one on hand. This volume details nine of the most versatile all-purpose mental models you can use right away to improve your decision making, your productivity, and how clearly you see the world.

Throughout his distinguished and unconventional career, engineer-turned-molecular-biologist Douglas Axe has been asking the questions that much of the scientific community would rather silence. Now, he presents his conclusions in this brave and pioneering book. Axe argues that the key to understanding our origin is the "design intuition" - the innate belief held by all humans that tasks we would need knowledge to accomplish can be accomplished only by someone who has that knowledge.

Over a storied career, Daniel C. Dennett has engaged questions about science and the workings of the mind. His answers have combined rigorous argument with strong empirical grounding. And a lot of fun. Intuition Pumps and Other Tools for Thinking offers seventy-seven of Dennett’s most successful “imagination-extenders and focus-holders” meant to guide you through some of life’s most treacherous subject matter: evolution, meaning, mind, and free will.

In this fascinating and illuminating work, Leonard Mlodinow guides us through the critical eras and events in the development of science, all of which, he demonstrates, were propelled forward by humankind's collective struggle to know. From the birth of reasoning and culture to the formation of the studies of physics, chemistry, biology, and modern-day quantum physics, we come to see that much of our progress can be attributed to simple questions - why? how? - bravely asked.

Science starts to get interesting when things don't make sense. Science's best-kept secret is that there are experimental results and reliable data that the most brilliant scientists can neither explain nor dismiss. If history is any precedent, we should look to today's inexplicable results to forecast the future of science. Michael Brooks heads to the scientific frontier to meet 13 modern-day anomalies and discover tomorrow's breakthroughs.

Scientific developments radically alter our understanding of the world. Whether it's technology, climate change, health research, or the latest revelations of neuroscience, physics, or psychology, science has, as Edge editor John Brockman says, "become a big story, if not the big story". In that spirit this new addition to Edge.org's fascinating series asks a powerful and provocative question: What do you consider the most interesting and important recent scientific news?

Many scientific and philosophical ideas are so powerful that they can be applied to our lives at home, work, and school to help us think smarter and more effectively about our behavior and the world around us. Surprisingly, many of these ideas remain unknown to most of us. In Mindware, the world-renowned psychologist Richard Nisbett presents these ideas in clear and accessible detail, offering a tool kit for better thinking and wiser decisions.

Does time exist? What is infinity? Why do mirrors reverse left and right but not up and down? In this scintillating collection, Holt explores the human mind, the cosmos, and the thinkers who’ve tried to encompass the latter with the former. With his trademark clarity and humor, Holt probes the mysteries of quantum mechanics, the quest for the foundations of mathematics, and the nature of logic and truth. Along the way, he offers intimate biographical sketches of celebrated and neglected thinkers, from the physicist Emmy Noether to the computing pioneer Alan Turing and the discoverer of fractals, Benoit Mandelbrot.

Under the aegis of machine learning in our data-driven machine age, computers are programming themselves and learning about - and solving - an extraordinary range of problems, from the mundane to the most daunting. Today it is machine learning programs that enable Amazon and Netflix to predict what users will like, Apple to power Siri's ability to understand voices, and Google to pilot cars.

Every physicist agrees quantum mechanics is among humanity's finest scientific achievements. But ask what it means, and the result will be a brawl. For a century, most physicists have followed Niels Bohr's Copenhagen interpretation and dismissed questions about the reality underlying quantum physics as meaningless. A mishmash of solipsism and poor reasoning, Copenhagen endured, as Bohr's students vigorously protected his legacy, and the physics community favored practical experiments over philosophical arguments.

Bayes' rule appears to be a straightforward, one-line theorem: by updating our initial beliefs with objective new information, we get a new and improved belief. To its adherents, it is an elegant statement about learning from experience. To its opponents, it is subjectivity run amok. Sharon Bertsch McGrayne here explores this controversial theorem and the human obsessions surrounding it.

How "Aha!" really happens....When do you get your best ideas? You probably answer "At night" or "In the shower" or "Stuck in traffic". You get a flash of insight. Things come together in your mind. You connect the dots. You say to yourself, "Aha! I see what to do." Brain science now reveals how these flashes of insight happen. It's a special form of intuition. We call it strategic intuition, because it gives you an idea for action - a strategy. This new book by William Duggan is the first full treatment of strategic intuition.

What is history, and why should we study it? Is there such a thing as historical truth? Is history a science? One of the most accomplished historians at work today, John Lewis Gaddis, answers these and other questions in this short, witty, and humane book. The Landscape of History provides a searching look at the historian's craft as well as a strong argument for why a historical consciousness should matter to us today.