Since the publication in 1859 of Charles Darwin's remarkable On the Origin of Species, the modern science of biology and genetics has added surprising new dimensions to evolutionary theory. In this course, you’ll discover what Darwin didn’t know, covering much of the curriculum of an introductory college course in evolutionary biology. No background in science is needed to follow these engaging lectures, delivered by Professor Scott Solomon of Rice University, a gifted teacher and widely traveled field biologist.

Each of us began life as a single cell. From this humble origin, we embarked on a risky journey fraught with opportunities for disaster. Yet, amazingly, we reached our destination intact, emerging as dazzlingly complex, exquisitely engineered assemblages of trillions of cells. This metamorphosis constitutes one of nature's most spectacular yet commonplace magic tricks—and one of its most coveted secrets. In From One Cell, physician and researcher Ben Stanger offers a glimpse into what scientists are discovering about how life and the body take shape.

From ants scurrying under leaf litter to bees able to fly higher than Mount Kilimanjaro, insects are everywhere. Three out of every four of our planet's known animal species are insects. In The Insect Crisis, Oliver Milman dives into the torrent of recent evidence that suggests this kaleidoscopic group of creatures is suffering the greatest existential crisis in its remarkable 400-million-year history.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

Joining the ranks of popular science classics like The Botany of Desire and The Selfish Gene, a groundbreaking, wondrously informative, and vastly entertaining examination of the most significant revolution in biology since Darwin - a "microbe's-eye view" of the world that reveals a marvelous, radically reconceived picture of life on Earth.

Why are conditions like autism, asthma, obesity, and allergies exploding at unprecedented rates? Why are we living longer, getting smarter, having far fewer kids? If Darwin were alive today, how would he explain this new world?

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

A list of the attributes that define a mammal is a ragbag of things - fur, live birth, three bones in the middle ear, a brain whose two halves are robustly joined together.... But this curious collection of features contain the roots of all the biology that makes us what we are: monkeys with massive brains who parent extensively, enjoy sport and think lots. Which is to say, what makes us mammals makes us human.

Why evolution is more than just a theory: it is a fact. In all the current highly publicized debates about creationism and its descendant "intelligent design", there is an element of the controversy that is rarely mentioned: the evidence, the empirical truth of evolution by natural selection.

From the very beginning, life on Earth has been defined by war. Today, those first wars continue to be fought around and literally inside us, influencing our individual behavior and that of civilization as a whole. War between populations - whether between different species or between rival groups of humans - is seen as an inevitable part of the evolutionary process. The popular concept of "the survival of the fittest" explains and often excuses these actions.

Suddenly, research findings require a paradigm shift in our view of the microbial world. The Human Microbiome Project at the National Institutes of Health is well under way, and unprecedented scientific technology now allows the censusing of trillions of microbes inside and on our bodies as well as in the places where we live, work, and play. This intriguing, up-to-the-minute book for scientists and nonscientists alike explains what researchers are discovering about the microbe world and what the implications are for modern science and medicine.

In Cracking the Aging Code, theoretical biologist Josh Mitteldorf and award-winning writer and ecological philosopher Dorion Sagan reveal that evolution and aging are even more complex and breathtaking than we originally thought. Using meticulous multidisciplinary science as well as reviewing the history of our understanding about evolution, this book makes the case that aging is not something that "just happens", nor is it the result of wear and tear or a genetic inevitability.

What can fossilized teeth tell us about our ancient life expectancy? What can big data on fossils reveal about farming's problematic role in human evolution? How can simple geometric comparisons of skull and pelvic fossils suggest an origin to our social nature? In Close Encounters with Humankind, paleoanthropologist Sang-Hee Lee explores some of our biggest evolutionary questions from unexpected new angles. Through a series of entertaining, bite-sized chapters, we gain new perspectives into our first hominin ancestors, our first steps on two feet, and more.

In our unique genomes, every one of us carries the story of our species - births, deaths, disease, war, famine, migration, and a lot of sex. But those stories have always been locked away - until now. Who are our ancestors? Where did they come from? Geneticists have suddenly become historians, and the hard evidence in our DNA has completely upended what we thought we knew about ourselves. Acclaimed science writer Adam Rutherford explains exactly how genomics is completely rewriting the human story - from 100,000 years ago to the present.

DNA is the genetic material that defines us as individuals. Over the last two decades, it has emerged as a powerful tool for solving crimes and determining guilt and innocence. But, very recently, an important new aspect of DNA has been revealed: it contains a detailed record of evolution. That is, DNA is a living chronicle of how the marvelous creatures that inhabit our planet have adapted to its many environments, from the freezing waters of the Antarctic to the lush canopy of the rain forest.

Why are conditions like autism, asthma, obesity, and allergies exploding at unprecedented rates? Why are we living longer, getting smarter, having far fewer kids? If Darwin were alive today, how would he explain this new world?

This new book by Spencer Wells, the internationally known geneticist, anthropologist, author, and director of the Genographic Project, focuses on the seminal event in human history: mankind's decision to become farmers rather than hunter-gatherers.

Suddenly, research findings require a paradigm shift in our view of the microbial world. The Human Microbiome Project at the National Institutes of Health is well under way, and unprecedented scientific technology now allows the censusing of trillions of microbes inside and on our bodies as well as in the places where we live, work, and play. This intriguing, up-to-the-minute book for scientists and nonscientists alike explains what researchers are discovering about the microbe world and what the implications are for modern science and medicine.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.

Just in the last three years a flood of new scientific findings, driven by revelations discovered in the human genome, has provided compelling new answers to many long-standing mysteries about our most ancient ancestors, the people who first evolved in Africa and then went on to colonize the whole world. Nicholas Wade weaves this host of news-making findings together for the first time into an intriguing new history of the human story before the dawn of civilization.

In Missing Microbes, Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now this invisible eden is being irrevocably damaged by some of our most revered medical advances-antibiotics-threatening the extinction of our irreplaceable microbes with terrible health consequences.

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

In movies, in novels, in comic strips, and on television, we've all seen dinosaurs - or at least somebody's educated guess of what they would look like. But what if it were possible to build, or grow, a real dinosaur without finding ancient DNA? Jack Horner, the scientist who advised Steven Spielberg on the blockbuster film Jurassic Park and a pioneer in bringing paleontology into the 21st century, teams up with the editor of the New York Times's Science Times section to reveal exactly what's in store.

Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.

From the very beginning, life on Earth has been defined by war. Today, those first wars continue to be fought around and literally inside us, influencing our individual behavior and that of civilization as a whole. War between populations - whether between different species or between rival groups of humans - is seen as an inevitable part of the evolutionary process. The popular concept of "the survival of the fittest" explains and often excuses these actions.

Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way.

When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.

Asserting that religious creeds and philosophical questions can be reduced to purely genetic and evolutionary components, and that the human body and mind have a physical base obedient to the laws of physics and chemistry, Genesis demonstrates that the only way for us to fully understand human behavior is to study the evolutionary histories of nonhuman species. Of these, Wilson demonstrates that at least 17 - among them the African naked mole rat and the sponge-dwelling shrimp - have been found to have advanced societies based on altruism and cooperation.

Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks listeners through the astonishing and controversial process of de-extinction.