Robert Sapolsky’s Behave, his now classic account of why humans do good and why they do bad, pointed toward an unsettling conclusion: We may not grasp the precise marriage of nature and nurture that creates the physics and chemistry at the base of human behavior, but that doesn’t mean it doesn’t exist. Now, in Determined, Sapolsky takes his argument all the way, mounting a brilliant (and in his inimitable way, delightful) full-frontal assault on the pleasant fantasy that there is some separate self telling our biology what to do.

At every moment, within our bodies and all around us, trillions of microscopic combatants are waging a war that shapes our health and life on Earth. Countless times per second, viruses known as phages attack and destroy bacteria while leaving all other life forms, including us, unscathed. Vastly outnumbering the viruses that do us harm, phages power ecosystems, drive evolutionary innovation, and harbor a remarkable capacity to heal life-threatening infections when conventional antibiotics fail. Yet most of us have never heard of them, thinking of viruses only as enemies to be feared.

For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight-how the same simple chemistry gives rise to life and causes our demise.

You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door. So what, exactly, is your immune system? In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defenses.

We are approaching a critical threshold in the history of our species. Everything is about to change. Soon you will live surrounded by AIs. They will organize your life, operate your business, and run core government services. You will live in a world of DNA printers and quantum computers, engineered pathogens and autonomous weapons, robot assistants and abundant energy. None of us are prepared. As co-founder of DeepMind, part of Google, Mustafa Suleyman has been at the center of this revolution. The coming decade, he argues, will be defined by this wave of powerful new technologies.

For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

Just over 125,000 years ago, humanity was going extinct until a dramatic shift occurred—Homo sapiens started tracking the tides in order to eat the nearby oysters. Before long, they’d pulled themselves back from the brink of extinction. The human brain, and its evolutionary journey, is unlike anything else in history. In A History of the Human Brain, Bret Stetka takes listeners through that far-reaching journey. He also tackles the question of where the brain will take us next, exploring the burgeoning con­cepts of epigenetics and new technologies like CRISPR.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

Achieve more with less effort: The secret to weight loss, fitness, and wellness lies in the most basic and most overlooked function of your body - how you breathe. One of the biggest obstacles to better health and fitness is a rarely identified problem: chronic overbreathing. We often take many more breaths than we need without realizing it, contributing to poor health and fitness, including a host of disorders, from anxiety and asthma to insomnia and heart problems.

Drawing on his decades of field research and up-to-the-minute understanding of the latest science, renowned geologist Andrew H. Knoll delivers a rigorous yet accessible biography of Earth, charting our home planet's epic 4.6 billion-year story. Placing 21st-century climate change in deep context, A Brief History of Earth is an indispensable look at where we’ve been and where we’re going.

What if we held within our minds the potential to transform our personal lives and the collective life of our species? In this unabridged audio of the updated and expanded 10th-anniversary edition of the book, you’ll learn how to turn the immense power of your subconscious into your most valuable tool for health, well-being, and much more.

James D. Watson, the Nobel laureate whose pioneering work helped unlock the mystery of DNA's structure, charts the greatest scientific journey of our time, from the discovery of the double helix to today's controversies to what the future may hold. Updated to include new findings in gene editing, epigenetics, and agricultural chemistry as well as two entirely new chapters on personal genomics and cancer research. This is the most comprehensive and authoritative exploration of DNA's impact on our society and our world.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

Astrophysicist Neil deGrasse Tyson has attracted one of the world’s largest online followings with his fascinating, widely accessible insights into science and our universe. Now, Tyson invites us to go behind the scenes of his public fame by unveiling his candid correspondence with people across the globe who have sought him out in search of answers. In this hand-picked collection of 100 letters, Tyson draws upon cosmic perspectives to address a vast array of questions about science, faith, philosophy, life, and of course, Pluto.

Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.

Welcome to the Universe is a personal guided tour of the cosmos by three of today's leading astrophysicists. Inspired by the enormously popular introductory astronomy course that Neil deGrasse Tyson, Michael A. Strauss, and J. Richard Gott taught together at Princeton, this book covers it all - from planets, stars, and galaxies to black holes, wormholes, and time travel.

How the Earth Works takes you on an astonishing journey through time and space. In 48 lectures, you will look at what went into making our planet - from the big bang, to the formation of the solar system, to the subsequent evolution of Earth.

Hilarious, fascinating, and a roller coaster of dizzying, historical what-ifs, Napoleon's Hemorrhoids is a potpourri for serious historians and casual history buffs. In one of Phil Mason's many revelations, you'll learn that Communist jets were two minutes away from opening fire on American planes during the Cuban missile crisis, when they had to turn back as they were running out of fuel. You'll discover that before the Battle of Waterloo, Napoleon's painful hemorrhoids prevented him from mounting his horse to survey the battlefield.

Chemistry and Our Universe: How It All Works is your in-depth introduction to this vital field, taught through 60 engaging half-hour lectures that are suitable for any background or none at all. Covering a year’s worth of introductory general chemistry at the college level, plus intriguing topics that are rarely discussed in the classroom, this amazingly comprehensive course requires nothing more advanced than high-school math. Your guide is Professor Ron B. Davis, Jr., a research chemist and award-winning teacher at Georgetown University.

From launchpad explosions to a pernicious cricket infestation to the demanding management style of Musk himself, the rise of SpaceX was beset with challenges and far from inevitable. Find out how the startup beat the odds and flew high enough to outpace their rivals... and where they're going next.

In this illuminating audiobook, Tyson and coauthor James Trefil, a renowned physicist and science popularizer, take on the big questions that humanity has been posing for millennia - How did life begin? What is our place in the universe? Are we alone? - and provide answers based on the most current data, observations, and theories.

From batting averages and political polls to game shows and medical research, the real-world application of statistics continues to grow by leaps and bounds. How can we catch schools that cheat on standardized tests? How does Netflix know which movies you'll like? What is causing the rising incidence of autism? As best-selling author Charles Wheelan shows us in Naked Statistics, the right data and a few well-chosen statistical tools can help us answer these questions and more.

How do today's most successful tech companies - Amazon, Google, Facebook, Netflix, Tesla - design, develop, and deploy the products that have earned the love of literally billions of people around the world? Perhaps surprisingly, they do it very differently from the vast majority of tech companies. In Inspired, technology product management thought leader Marty Cagan provides listeners with a master class in how to structure and staff a vibrant and successful product organization and how to discover and deliver technology products that your customers will love.

By the mid 1980s, AIDS hysteria was so rampant that a fearful and prejudiced public ignored stories of gay men falling ill with lesions and mouth ulcers. President Reagan avoided mentioning the disease entirely. Then, as chronicled in Blood Farm, a new HIV-positive population emerged, one that included kids like Ken Dixon, Brad Cross, and Ryan White who had been infected as young as ten years old. But how?

Invisible in the food we eat, the people we kiss, and inside our own bodies, viruses flourish - with the power to shape not only our health, but our social, political, and economic systems. Drawing on his expertise in microbiology, Joseph Osmundson brings listeners under the microscope to understand the structure and mechanics of viruses and to examine how viruses like HIV and COVID-19 have redefined daily life. Virology is a critical warning, a necessary reflection, and a call for a better future.

Could humans unknowingly be a part of a larger superorganism—one with its own motivations and goals, one that is alive, and conscious, and has the power to shape the future of our species? This is the fascinating theory from author and futurist Byron Reese, who calls this human superorganism “Agora.” In We Are Agora, Reese starts by asking the question, “What is life and how did it form?” From there, he looks at how multicellular life came about, how consciousness emerged, and how other superorganisms in nature have formed.

What is life? In this penetrating and wide-ranging book, world-renowned physicist and science communicator Paul Davies searches for answers in a field so new and fast-moving that it lacks a name; it is a domain where biology, computing, logic, chemistry, quantum physics, and nanotechnology intersect.

Black holes are the most extreme objects in the universe, and yet they are ubiquitous. Frighteningly enigmatic, these dark giants continue to astound even the scientists who spend their careers studying them. Einstein’s Monsters reveals how our comprehension of black holes is intrinsically linked to how we make sense of the universe and our place within it. From the small questions to the big ones - from the tiniest particles to the nature of space-time itself - black holes might be the key to a deeper understanding of the cosmos.

The Indian subcontinent was the scene of dramatic upheavals a few thousand years ago. The Northwest region entered an arid phase, and erosion coupled with tectonic events played havoc with river courses. One of them disappeared. Celebrated as Sarasvati in the Rig Veda and the Mahabharata, this river was rediscovered in the early 19th century through topographic explorations by British officials. Recently, geological and climatological studies have probed its evolution and disappearance, while satellite imagery has traced the river's buried courses....

The American war in Vietnam has left many long-lasting scars that have not yet been sufficiently examined. The worst of them were inflicted in a tiny area bounded by the demilitarized zone between North and South and the Ho Chi Minh Trail in neighboring Laos. That small region saw the most intense aerial bombing campaign in history, the massive use of toxic chemicals, and the heaviest casualties on both sides.

Iceland is home to only 330,000 people but more than 265 museums and public collections, ranging from the intensely physical, like the Icelandic Phallological Museum, which collects the penises of every mammal known to exist in Iceland, to the vaporously metaphysical, like the Museum of Icelandic Sorcery and Witchcraft, which poses a particularly Icelandic problem: how to display what can't be seen?

With temperatures rising and the risk of disasters growing, our world is increasingly vulnerable. Most people see disasters as freak, natural events that are unpredictable and unpreventable. But that simply isn’t the case - disasters are avoidable, but when they do strike, there are strategic ways to manage the fallout.

In a remote pocket of Nazi-held France, ordinary people risked their lives to rescue many hundreds of strangers, mostly Jewish children. Was this a fluke of history, or something more? Anthropologist Maggie Paxson, certainties shaken by years of studying strife, arrives on the Plateau to explore this phenomenon: What are the traits that make a group choose selflessness?

Alyssa Ages was the strongest she’d ever been, able to flip monster truck tires and walk with 300 pounds on her back. She felt invincible, until the day her body betrayed her, leaving her vulnerable and grasping for control. Rebuilding her strength slowly brought her back to life. She began to wonder: What if strength isn't about how much we can lift? What if it's about how we manage life’s struggles? In Secrets of Giants, Ages, now a mom of two, embarks on an immersive journey to the fringe of the weight-lifting world, the sport of strongman.

Humanity has long looked to the sky and marveled at the world around us. We've wondered why the world is the way it is and whether it has to be that way. And we dream of a time when we have developed a theory of everything—a theory that answers all questions. Einstein's Unfinished Dream explores the cutting-edge research of modern particle physicists that pushes us slowly towards a theory of everything....

Just as the documentary Eyes on the Prize captured the rich drama of the civil rights movement, Sacred Liberty brings to life the remarkable story of how America became one of the few nations in world history that has religious freedom, diversity, and high levels of piety at the same time. Finally, Sacred Liberty provides a road map for how, in the face of modern threats to religious freedom, this great achievement can be preserved.

VC tells the riveting story of how the industry arose from the United States' long-running orientation toward entrepreneurship. Venture capital has been driven from the start by the pull of outsized returns through a skewed distribution of payoffs - a faith in low-probability but substantial financial rewards that rarely materialize. Whether the gamble is a whaling voyage setting sail from New Bedford or the newest startup in Silicon Valley, VC is not just a model of finance that has proven difficult to replicate in other countries.

The Book of Phobias and Manias is a thrilling compendium of 99 obsessions that have shaped us all, the rare and the familiar, from ablutophobia (a horror of washing) to syllogomania (a compulsion to hoard) to zoophobia (a fear of animals).