She Has Her Mother's Laugh
The Powers, Perversions, and Potential of Heredity
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Narrated by:
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Joe Ochman
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By:
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Carl Zimmer
About this listen
2019 PEN/E.O. Wilson Literary Science Writing Award Finalist
"Science book of the year"—The Guardian
One of New York Times 100 Notable Books for 2018
One of Publishers Weekly's Top Ten Books of 2018
One of Kirkus's Best Books of 2018
One of Mental Floss's Best Books of 2018
One of Science Friday's Best Science Books of 2018
“Extraordinary”—New York Times Book Review
"Magisterial"—The Atlantic
"Engrossing"—Wired
"Leading contender as the most outstanding nonfiction work of the year"—Minneapolis Star-Tribune
Celebrated New York Times columnist and science writer Carl Zimmer presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities...
But, Zimmer writes, “Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are—our appearance, our height, our penchants—in inconceivably subtle ways.” Heredity isn’t just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors—using a word that once referred to kingdoms and estates—but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer’s lucid exposition and storytelling, this resounding tour de force delivers it.
Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world’s best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.
©2018 Carl Zimmer (P)2018 Penguin AudioListeners also enjoyed...
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“Extraordinary...This book is Zimmer at his best: obliterating misconceptions about science with gentle prose. He brings the reader on his journey of discovery as he visits laboratory after laboratory, peering at mutant mosquitoes and talking to scientists about traces of Neanderthal ancestry within his own genome. Any fan of his previous books or his journalism will appreciate this work. But so, too, will parents wishing to understand the magnitude of the legacy they’re bequeathing to their children, people who want to grasp their history through genetic ancestry testing and those seeking a fuller context for the discussions about race and genetics so prevalent today.”—The New York Times Book Review
"Zimmer dispels longstanding scientific misconceptions, introduces facts that may surprise you and brings readers on a delightful journey of genetic discovery."—The New York Times, "Paperback Row"
“Magisterial...In Zimmer’s pages, we discover a world minutely threaded with myriad streams of heredity flowing in all directions, in variegated patterns and different registers.”—The Atlantic
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When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.
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A quick read - hard to put down
- By Digital Dilema on 09-06-13
By: George Johnson
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How to Build a Dinosaur
- Extinction Doesn't Have to Be Forever
- By: Jack Horner, James Gorman
- Narrated by: Patrick Lawlor
- Length: 6 hrs and 36 mins
- Unabridged
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In movies, in novels, in comic strips, and on television, we've all seen dinosaurs - or at least somebody's educated guess of what they would look like. But what if it were possible to build, or grow, a real dinosaur without finding ancient DNA? Jack Horner, the scientist who advised Steven Spielberg on the blockbuster film Jurassic Park and a pioneer in bringing paleontology into the 21st century, teams up with the editor of the New York Times's Science Times section to reveal exactly what's in store.
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Good book but misplaced title
- By Robert on 06-19-15
By: Jack Horner, and others
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- By: Daniel M. Davis
- Narrated by: Christopher Grove
- Length: 7 hrs and 48 mins
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Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
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A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- By: Jennifer A. Doudna, Samuel H. Sternberg
- Narrated by: Erin Bennett
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Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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In to the abyss we ascend, a scary future
- By Philomath on 06-17-17
By: Jennifer A. Doudna, and others
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An Epidemic of Absence
- A New Way of Understanding Allergies and Autoimmune Diseases
- By: Moises Velasquez-Manoff
- Narrated by: Chris Sorensen
- Length: 17 hrs and 6 mins
- Unabridged
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An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
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The point of view from a Veterinarian immunologist
- By rtgymnast on 11-03-17
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Herding Hemingway's Cats
- Understanding How Our Genes Work
- By: Kat Arney
- Narrated by: Kat Arney
- Length: 8 hrs and 39 mins
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The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work?
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A non-scientists misguided interpretation
- By AraSevera on 05-15-16
By: Kat Arney
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Superlative
- The Biology of Extremes
- By: Matthew D. LaPlante
- Narrated by: George Newbern
- Length: 9 hrs and 27 mins
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The world's largest land mammal could help us end cancer. The fastest bird is showing us how to solve a century-old engineering mystery. The oldest tree is giving us insights into climate change. The loudest whale is offering clues about the impact of solar storms. For a long time, scientists ignored superlative life forms as outliers. Increasingly, though, researchers are coming to see great value in studying plants and animals that exist on the outermost edges of the bell curve.
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Fascinating survey of amazing biology
- By Nerd's-eye view on 12-06-19
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Neanderthal Man
- In Search of Lost Genomes
- By: Svante Pääbo
- Narrated by: Dennis Holland
- Length: 10 hrs and 36 mins
- Unabridged
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A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.
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Excellent science tale
- By Neuron on 01-19-15
By: Svante Pääbo
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Pandora's Seed
- The Unforeseen Cost of Civilization
- By: Spencer Wells
- Narrated by: Spencer Wells
- Length: 6 hrs and 40 mins
- Unabridged
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This new book by Spencer Wells, the internationally known geneticist, anthropologist, author, and director of the Genographic Project, focuses on the seminal event in human history: mankind's decision to become farmers rather than hunter-gatherers.
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Short and unfocused, but often quite interesting.
- By Alan on 06-23-10
By: Spencer Wells
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At the Edge of Uncertainty
- 11 Discoveries Taking Science by Surprise
- By: Michael Brooks
- Narrated by: Sean Runnette
- Length: 9 hrs and 12 mins
- Unabridged
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The atom, the big bang, DNA, natural selection - all are ideas that have revolutionized science; and all were dismissed out of hand when they first appeared. The surprises haven't stopped in recent years, and in At the Edge of Uncertainty, best-selling author Michael Brooks investigates the new wave of radical insights that are shaping the future of scientific discovery.
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All smoke, no fire
- By Kenton on 07-25-15
By: Michael Brooks
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Time, Love, Memory
- A Great Biologist and His Quest for the Origins of Behavior
- By: Jonathan Weiner
- Narrated by: Kevin Pariseau
- Length: 11 hrs and 37 mins
- Unabridged
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Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch, brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.
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This is a profound science book
- By Timothy A. Smith on 05-12-10
By: Jonathan Weiner
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Vagina Obscura
- An Anatomical Voyage
- By: Rachel E. Gross
- Narrated by: Siho Ellsmore
- Length: 10 hrs and 50 mins
- Unabridged
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The Latin term for the female genitalia, pudendum, means “parts for which you should be ashamed”. Until 1651, ovaries were called female testicles. The fallopian tubes are named for a man. Named, claimed, and shamed: Welcome to the story of the female body, as penned by men. Today, a new generation of (mostly) women scientists is finally redrawing the map. With modern tools and fresh perspectives, they’re looking at the organs traditionally bound up in reproduction—the uterus, ovaries, vagina—and seeing within them a new biology of change and resilience.
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poor narration
- By Jane on 08-23-22
By: Rachel E. Gross
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Headstrong
- 52 Women Who Changed Science-and the World
- By: Rachel Swaby
- Narrated by: Lauren Fortgang
- Length: 7 hrs and 1 min
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In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation.
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Role models for young women
- By mtsuda90 on 06-25-16
By: Rachel Swaby
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Moonwalking with Einstein
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An instant best seller that is poised to become a classic, Moonwalking with Einstein recounts Joshua Foer's yearlong quest to improve his memory under the tutelage of top "mental athletes". He draws on cutting-edge research, a surprising cultural history of remembering, and venerable tricks of the mentalist's trade to transform our understanding of human memory. From the United States Memory Championship to deep within the author's own mind, this is an electrifying work of journalism that reminds us that, in every way that matters, we are the sum of our memories.
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What listeners say about She Has Her Mother's Laugh
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Karen Trythall
- 08-13-19
Fascinating target shift
Great genetics historic overview with information shifting for youth to elderly as in popular page turned genres. Entertaining. Informative.
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- Amazon Customer
- 12-15-23
Intriguing Insights
The concept of mosaic inheritance was mind boggling. Also the idea that DNA from my daughter and her father may be lingering in my body is awesome. The exploration of the range of possibilities of how DNA forms each person’s individual sexuality is truly eye opening.
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- Nenn
- 08-20-18
Very informative!
If you like reading research on research, this book in incredibly informative! From the philosophical arguments about heredity to the current science and status of genetic engineering, this book is a thorough and interesting investigation into how we perceive WHAT we are is passed on to future generations. Not only is the scientific significance examined, but as well as the ethical and legal ramifications of these findings.
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5 people found this helpful
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- Christopher Dulaney
- 03-28-19
excellent science writing
I picked this title because I hoped to develop a better understanding genetic heredity. The book delivers a social and scientific history of the concept of heredity: from the development of royal bloodlines and family trees to the rise of racism and eugenics. It was as interesting to learn about this history as it was to delve into the future of gene editing and its moral and social implications. I throughly enjoyed this book.
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- drbobo
- 08-06-18
Amazing overview
Highly recommended. May be too much detail for some but still an excellent resource. Worthy of your time :-)
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5 people found this helpful
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- derek veazey
- 08-07-18
Good overview of inheritance
Starts off slow with stories that have little to do with inheritance, but I'm glad I stuck with it. Zimmer provides a good up to date research in genentics. A good overview for anyone interested in the study of heredity.
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1 person found this helpful
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- James Tharpe
- 01-15-21
Multiple mind-blowing moments
From history you never imagined to evolutionary quirks you've never heard of, this book is continually mind-blowing.
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- Chetzmom4
- 01-19-19
The Zombie Apocalypse is coming.
I am not a scientist, but I like science books. Though some of this became a bit dry, I still picked up enough that I really enjoyed it. The history of geneticists, and how their ideas & theories ~ interestingly ~ evolved was fascinating! The stories used to explain the science progress, help to make it relatable. This is how genes & our definition of hereditary relates to actual humans (and other animals).
All the "fun" dissipated in the final chapters. Scientists sitting in a corporation's lab, trying to come up with a gene to make insects infertile, or creating a way to make natural conception unnecessary. Corporations do not care about the results of their actions. They ONLY care if it makes immediate profits.
To quote Dr.Ian Malcolm from Jurassic Park,
"Your scientists were so preoccupied with whether they could, they didn't stop to think if they should." The world is a big place, and it's only a matter of time, before we "science" ourselves right out of it.
Enter, Stage right...Zombie Apocalypse.
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- William L Eckman
- 01-08-19
Zimmer is one of the best popular science writers.
Most scientists suffer from what is known as the curse of knowledge a cognitive bias that occurs when an individual, communicating with other individuals, unknowingly assumes that the others have the background to understand. Zimmer isn't a scientist instead he's an exemplary story teller. He's crafted this abstruse subject matter into a narrative more akin to a story. This is my first book of his that I've read and it won't be my last.
I think one of the biggest challenges for a sweeping story like this for the author is their conclusion or summarization. But in the final chapter Zimmer adroitly pulled the story of heredity in particular and genetics more broadly into a cautionary tale with cause for optimism as well as worry. This is a very good book.
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- Michael Daniec
- 08-26-20
Fascinating in breadth and depth
A fascinating, near encyclopedic. review of history and current state of genetics and heredity. Masterful presentation that manages to convey the highlights and some of the arcana to deepen our understanding of this fundamental and important body of knowledge. of ourselves.
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