Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells - taken without her knowledge - became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than 60 years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects.

For the last 20 years, George Saunders has been teaching a class on the Russian short story to his MFA students at Syracuse University. In A Swim in a Pond in the Rain, he shares a version of that class with us, offering some of what he and his students have discovered together over the years. Paired with iconic short stories by Chekhov, Turgenev, Tolstoy, and Gogol, the seven essays in this book are intended for anyone interested in how fiction works and why it’s more relevant than ever in these turbulent times.

In the eyes of eighteen-year-old Hua Hsu, the problem with Ken—with his passion for Dave Matthews, Abercrombie & Fitch, and his fraternity—is that he is exactly like everyone else. Ken, whose Japanese American family has been in the United States for generations, is mainstream; for Hua, the son of Taiwanese immigrants, who makes ’zines and haunts Bay Area record shops, Ken represents all that he defines himself in opposition to. The only thing Hua and Ken have in common is that, however they engage with it, American culture doesn’t seem to have a place for either of them.

If you've ever laughed your way through David Sedaris's cheerfully misanthropic stories, you might think you know what you're getting with Calypso. You'd be wrong. When he buys a beach house on the Carolina coast, Sedaris envisions long, relaxing vacations spent playing board games and lounging in the sun with those he loves most. And it's as idyllic as he imagined, except for one tiny, vexing realization: it's impossible to take a vacation from yourself. With Calypso, Sedaris sets his formidable powers of observation - and dark humor - toward middle age and mortality.

Javier Zamora’s adventure is a three-thousand-mile journey from his small town in El Salvador, through Guatemala and Mexico, and across the U.S. border. He will leave behind his beloved aunt and grandparents to reunite with a mother who left four years ago and a father he barely remembers. Traveling alone amid a group of strangers and a “coyote” hired to lead them to safety, Javier expects his trip to last two short weeks.

We meet Andrew Leland as he’s suspended in the liminal state of the soon-to-be blind: he’s midway through his life with retinitis pigmentosa, a condition that ushers those who live with it from sightedness to blindness over years, even decades. He grew up with full vision, but starting in his teenage years, his sight began to degrade from the outside in. Soon— but without knowing exactly when—he will likely have no vision left. Full of apprehension but also dogged curiosity, Leland embarks on a sweeping exploration of the state of being that awaits him.

Playwright, author, and activist Eve Ensler has devoted her life to the female body - how to talk about it, how to protect and value it. Yet she spent much of her life disassociated from her own body - a disconnection brought on by her father’s sexual abuse and her mother’s remoteness. “Because I did not, could not inhabit my body or the Earth,” she writes, “I could not feel or know their pain.” But Ensler is shocked out of her distance.

Bringing a poetic sensibility to her prose to stunning effect, Lythcott-Haims briskly and stirringly evokes her personal battle with the low self-esteem that American racism routinely inflicts on people of color. The only child of a marriage between an African-American father and a white British mother, she shows indelibly how so-called "micro" aggressions in addition to blunt force insults can puncture a person's inner life with a thousand sharp cuts.

It’s 2011, and Samuel Andresen-Anderson—college professor, stalled writer—has a Nix of his own: his mother, Faye. He hasn’t seen her in decades, not since she abandoned the family when he was a boy. Now she’s re-appeared, having committed an absurd crime that electrifies the nightly news, beguiles the internet, and inflames a politically divided country. The media paints Faye as a radical hippie with a sordid past, but as far as Samuel knows, his mother was an ordinary girl who married her high-school sweetheart.

As an end-of-life doula, Nova Huston’s job - her calling, her purpose, her life - is to help terminally ill people make peace with their impending death. Unlike her business partner, who swears by her system of checklists, free-spirited Nova doesn’t shy away from difficult clients: the ones who are heartbreakingly young, or prickly, or desperate for a caregiver or companion.

Recently selected Best Author by readers of Entertainment Weekly, Nicholas Sparks is one of America's preeminent storytellers. Now, Sparks spins a tale about a man, a woman, and the devastating secret that threatens to keep them apart.

When a letter that was never meant to be seen by anyone draws high school senior Evan Hansen into a family's grief over the loss of their son, he is given the chance of a lifetime: to belong. He just has to stick to a lie he never meant to tell: that the notoriously troubled Connor Murphy was his secret best friend. Suddenly, Evan isn't invisible anymore - even to the girl of his dreams. And Connor Murphy's parents, with their beautiful home on the other side of town, have taken him in like he was their own, desperate to know more about their enigmatic son from his closest friend.

In rural Virginia, Young and Pak Yoo run an experimental medical treatment device known as the Miracle Submarine - a pressurized oxygen chamber that patients enter for therapeutic "dives" with the hopes of curing issues like autism or infertility. But when the Miracle Submarine mysteriously explodes, killing two people, a dramatic murder trial upends the Yoos’ small community. Who or what caused the explosion? Was it the mother of one of the patients, who claimed to be sick that day but was smoking down by the creek? Or was it Young and Pak themselves?

When Sarah meets Eddie, they connect instantly and fall in love. To Sarah, it seems as though her life has finally begun. And it's mutual: It's as though Eddie has been waiting for her, too. Sarah has never been so certain of anything. So when Eddie leaves for a long-booked vacation and promises to call from the airport, she has no cause to doubt him. But he doesn't call. Sarah's friends tell her to forget about him, but she can't. She knows something's happened - there must be an explanation.

A hopeful look at coping with the ravages of serious chronic illness by an accomplished journalist, a contributing columnist for the New York Times, and former senior producer of the CBS Evening News.

When Lizzie’s car crashes with her two daughters inside, she faces a terrible choice. And when she recovers from her injuries, she must deal with the impact of that tragedy and the police investigation into it. As Lizzie and her family struggle to come to terms with the events of that night, things take an even darker turn. What exactly happened on that remote country road? Who is responsible? And can the family get through this together…or will the truth finally tear them apart?

During a terrible heat wave in 1991 - the worst in a decade - 10-year-old Anton has been locked in an apartment in the projects, alone, for seven days, without air conditioning or a fan. With no electricity, the refrigerator and lights do not work. Hot, hungry, and desperate, Anton shatters a window and climbs out. Cutting his leg on the broken glass, he is covered in blood when the police find him. Juanita, his mother, is discovered in a crack house less than three blocks away, nearly unconscious and half-naked.

While his successful wife goes off to her law office each day, Simon Connolly takes care of their kids, Jake and Laney. Now that they are in high school, the angst-ridden father should feel more relaxed, but he doesn't. He's seen the statistics, read the headlines. And now, his darkest fear is coming true. There has been a shooting at school.

From the moment Martha and her husband, John, conceived their second child, all hell broke loose. They were a couple obsessed with success. After years of matching IQs and test scores with less driven peers, they had two Harvard degrees apiece and were gunning for more. But the dream had begun to disintegrate. Then, when their unborn son, Adam, was diagnosed with Down syndrome, doctors, advisers, and friends in the Harvard community warned them not to keep the baby.

What’s happening in Acker’s Gap, West Virginia? Three elderly men are gunned down over their coffee at a local diner, and seemingly half the town is there to witness the act. Still, it happened so fast, and no one seems to have gotten a good look at the shooter. Was it random? Was it connected to the spate of drug violence plaguing poor areas of the country just like Acker’s Gap? Or were Dean Streeter, Shorty McClurg, and Lee Rader targeted somehow?

What does it really mean to be a man? In Man Alive, Thomas Page McBee attempts to answer that question by focusing on two of the men who most impacted his life - one, his otherwise ordinary father who abused him as a child, and the other, a mugger who almost killed him. Standing at the brink of the life-changing decision to transition from female to male, McBee seeks to understand these examples of flawed manhood and tells us how a brush with violence sent him on the quest to untangle a sinister past and freed him to become the man he was meant to be.

Years and distance kept the memories at bay. But back at home, the past is ready and waiting to haunt her... Eighteen years have passed since Joy's childhood best friend, Jenny, met her death in a tragic car accident just a few days after their senior prom. A broken Joy left their small Kentucky hometown shortly after - determined never to come back. But when her father's illness forces her to return, she realizes that neither time nor distance have truly healed her troubled soul.

Meet Riley Ellison, a smart, quirky, young library assistant who's become known in her hometown of Tuttle Corner, Virginia, as Riley Bless-Her-Heart. Ever since her beloved granddaddy died and her longtime boyfriend broke up with her, Riley has been withdrawing from life. In an effort to rejoin the living, she signs up for an online dating service and tries to reconnect with her childhood best friend, Jordan James, a reporter at the Tuttle Times.

Award-winning poet Marisa de los Santos crafts an irresistibly touching debut novel. Love Walked In is a contemporary tale, steeped in nostalgic, cinematic charm, of love in all its forms. Unapologetically idealistic about love, Cornelia Brown appears to catch the break of a lifetime when the dashing Martin Grace, her own personal Cary Grant, comes strolling into her life. But it is Martin's connection to 11-year-old Clare Hobbes that touches Cornelia's heart in ways she never imagined.

A fierce memoir of a mother's murder, a daughter's coming-of-age in the wake of immense loss, and her ultimate mission to know the woman who gave her life.

"Something is murdering my men." Thus reads the message received from a Nazi commander stationed in a small castle high in the remote Transylvanian Alps. Invisible and silent, the enemy selects one victim per night, leaving the bloodless and mutilated corpses behind to terrify its future victims. When an elite SS extermination squad is dispatched to solve the problem, the men find something that's both powerful and terrifying. Panicked, the Nazis bring in a local expert on folklore - who just happens to be Jewish - to shed some light on the mysterious happenings.

Real estate expert Olivia Bellamy reluctantly trades a trendy Manhattan summer for her family's old resort camp in the Catskills, where her primary task will be renovating the bungalow colony for her grandparents, who want one last summer together filled with fun, friends and family. A posh resort in its heyday, the camp is now in disarray and Olivia is forced to hire contractor Connor Davis - a still-smoldering flame from her own summers at camp.

True biz? The students at the River Valley School for the Deaf just want to hook up, pass their history finals, and have politicians, doctors, and their parents stop telling them what to do with their bodies. This revelatory novel plunges listeners into the halls of a residential school for the deaf, where they’ll meet Charlie, a rebellious transfer student who’s never met another deaf person before; Austin, the school’s golden boy, whose world is rocked when his baby sister is born hearing; and February, the hearing headmistress.

David Menasche lived for his work as a high school English teacher. His passion inspired his students, and between lessons on Shakespeare and sentence structure, he forged a unique bond with his kids, buoying them through personal struggles while sharing valuable life lessons.

For years, Sarah Farber and her best friend, Jennifer, kept what they called the Never List: A list of actions to be avoided at all costs, for safety’s sake. But one night, against their best instincts, they accept a cab ride -one with grave, everlasting consequences. For the next three years, they are held captive with two other girls in a dungeon-like cellar by a connoisseur of sadism. Ten years later, Sarah’s abductor is up for parole and she can no longer ignore the twisted letters he sends to her from prison.