Charlie Gordon knows that he isn't very bright. At 32, he mops floors in a bakery and earns just enough to get by. Three evenings a week, he studies at a center for mentally challenged adults. But all of this is about to change for Charlie. As part of a daring experiment, doctors are going to perform surgery on Charlie's brain. They hope the operation and special medication will increase his intelligence, just as it has for the laboratory mouse, Algernon.

Knowledge is power. That would be the motto of Lander University, had it not been snatched up and used to death by others long before the school was founded. For while Lander offers a full range of courses to nearly all students, it also offers a small number of specialty classes to a very select few.

Three people living lives they never wanted, hiding secrets that even those closest to them would never suspect, will find that the past never truly fades away. Even as the terrible consequences of long-ago events crash together in the present and threaten to ruin lives, they will come to the startling realization that they may not want to forget the past at all.

The Stranger appears out of nowhere, perhaps in a bar or a parking lot or at the grocery store. His identity is unknown. His motives are unclear. His information is undeniable. Then he whispers a few words in your ear and disappears, leaving you picking up the pieces of your shattered world.

Mia Hamilton lived the perfect life with her husband, university teacher Zach, and their two-year-old daughter. But everything changed when Zach committed suicide on the same night one of his students vanished. Five years later, just when Mia is beginning to heal, stranger Alison walks into her life, saying her husband didn't kill himself. Fragile, slight Alison leads Mia on a path into Zach's past, and Mia begins to think she never really knew her own husband.

Ophelia's husband disappears at the most inopportune times. After 10 years, she's not sure why she puts up with it, other than the fact that she's loved him since she first saw him in college, before the physics experiment that started Will involuntarily sliding through time. And there's nothing anyone can do about it. Or is there?

Every morning, A wakes in a different person’s body, a different person’s life. There’s never any warning about where it will be or who it will be. A has made peace with that, even established guidelines by which to live: Never get too attached. Avoid being noticed. Do not interfere. It’s all fine until the morning that A wakes up in the body of Justin and meets Justin’s girlfriend, Rhiannon. From that moment, the rules by which A has been living no longer apply....

They are just children when they first meet: Charlotte, daughter of the French ambassador, and Hiroshi, a laundress’s son. One day in the playground, Hiroshi declares that he has an idea that will change the world. An idea that will sweep away all differences between rich and poor. When Hiroshi runs into Charlotte several years later, he is trying to build a brighter future through robotics.

When reformed dream hacker Nix Nighthawk's sleep chip malfunctions, he is forced to seek help from a world he is trying to avoid - his old friends in the pirate dream network. But that world has changed, and Nix soon finds himself at the center of a complex plot to overthrow the vast corporation that controls every aspect of society.

At 30 years old, Phil is an unemployed gamer who struggles to make ends meet. His only source of income is freelance writing (when he feels inspired enough to add another article to his less-than-popular blog). His wife has just walked out on him, leaving him without money, purpose, or food in the fridge. On the day his wife dumps him, Phil receives a mysterious piece of wetware. A game interface seems to have been implanted in his brain, which allows him to see the world through the eyes of an RPG player. Now that Phil discovers his real-life stats, he can see they're below average.

Every day Iona, a larger-than-life magazine advice columnist, travels the ten stops from Hampton Court to Waterloo Station by train, accompanied by her dog, Lulu. Every day she sees the same people, whom she knows only by nickname: Impossibly-Pretty-Constant-Reader and Terribly-Lonely-Teenager. Of course, they never speak. Seasoned commuters never do. Then one morning, the man she calls Smart-But-Sexist-Manspreader chokes on a grape right in front of her. He’d have died were it not for the timely intervention of Sanjay, a nurse, who gives him the Heimlich maneuver.

Rebecca Wright has reclaimed her life, finding her way out of her grief and depression following a personal tragedy years ago. She spends her days working in customer support for the Internet dating site where she first met her husband. But she has a strange, persistent sense that everything around her is somewhat off-kilter: She constantly feels as if she has walked into a room and forgotten what she intended to do there; on TV, the president seems to be the wrong person in the wrong place; her dreams are full of disquiet.

Parker Santé hasn't spoken a word in five years. While his classmates plan for bright futures, he skips school to hang out in hotels, killing time by watching the guests. But when he meets a silver-haired girl named Zelda Toth, a girl who claims to be quite a bit older than she looks, he'll discover there just might be a few things left worth living for.

In the near future, a signal is detected coming from the Alpha Centauri system. Mysterious, unintelligible data streams in for ten years. Heather Davis, a professor in the University of Toronto psychology department, has devoted her career to deciphering the message. Her estranged husband, Kyle, is working on the development of artificial intelligence systems and new computer technology utilizing quantum effects to produce a near-infinite number of calculations simultaneously.

Abby Kimball has just moved to New England with her boyfriend and is trying to settle in, but the experience is proving to be quite unsettling, to say the least. While on a tour of local historic homes, Abby witnesses a family scene that leaves her gasping for breath - because the family has been dead for nearly a century. Another haunting episode follows, and another, until it seems to Abby that everything she touches is drawing her in, calling to her from the past.