A lorry crashes on a dark, wet road. In the wake of the tragedy, a dying man receives another chance at life - but does he really deserve it? And if he lives, will those around him wish he hadn't? When critically ill Jacob Wilson has a heart transplant, his behaviour becomes very strange. His worried parents and girlfriend try their best to understand his sudden mood swings, but as things worsen, they begin to live in terror of what they might find in their son's bedroom next - and as Jacob's personality morphs, so, too, do the lives of those around him....

After losing her job and boyfriend, Jan Hamlin is in desperate need of a fresh start. So she jumps at the chance to rent a secluded cottage on the edge of Coleshaw Woods. Very quickly though, things take a dark turn. At night, Jan hears strange noises, and faint taps at the window. Something, or someone, is out there.

Eight-year-old Leila Smith has seen and heard things that no child should ever have to. On the Hawthorn Estate, where she lives, she often stays out in the playground long after the other children have left, just so she can avoid her own home for longer. But what Leila doesn't know is that someone has been watching her. One day, she disappears without a trace. The police search start a nationwide search, but it's as if Leila has vanished into thin air. Who kidnapped her? What do they want? Will she return home safe and sound, or is she lost forever?

When Emily and Ben move in next door to Dr Burman and his wife, Anita, they are keen to get to know their new neighbours. Outgoing and sociable, Emily tries to befriend the doctor’s wife, but Anita is strangely subdued, barely leaving the house, and terrified of answering the phone. When Emily goes missing a few weeks later, Ben is plunged into a panic. His wife has left him a note, but can she really have abandoned him for another man? Or has Emily’s curiosity about the couple next door led her straight into danger?

Damian is just seven when he is taken in by foster carer Cathy Glass. His mother, Rachel, loves her three young children dearly, but she is vulnerable, naïve and unable to cope on her own. Cathy sets about helping Damian overcome his eating issues, with the hope that he will eventually return home. But when Rachel’s new boyfriend, Troy, arrives on the scene, Cathy becomes deeply concerned. She soon realises that Damian and his siblings are in great danger.

As I sit in her dimly lit bedroom, surrounded by flickering candles, I feel the crushing weight of my daughter’s absence. It's been two years since Layla was murdered. The police have searched tirelessly for her killer, but they've found nothing – it's like whoever did it vanished into thin air. My once-perfect marriage is falling apart, we can hardly look at each other anymore. Our ten-year-old son Gale is struggling. He’s changed since she died. He’s more secretive and also…

Every morning and evening, Zoe Walker takes the same route to the train station, waits at a certain place on the platform, finds her favorite spot in the car, never suspecting that someone is watching her. It all starts with a classified ad. During her commute home one night, while glancing through her local paper, Zoe sees her own face staring back at her - a grainy photo along with a phone number and a listing for a website called FindTheOne.com.

My darling son, Sam, is marrying his childhood sweetheart, and I couldn’t be prouder of the man he’s grown into. Walking out on his abusive father all those years ago was the best thing I ever did. And today he stands, tall and handsome, saying "I do" to my dream daughter-in-law. If I hadn’t pushed them together all those years ago, he might never have found a girl as perfect as Lauren. It’s true what they say, mother always knows best.

Special Agent Macy Crow is a survivor. After a vicious hit-and-run nearly kills her, she gets right back to work, and now she’s gunning for a spot on the FBI’s elite profiling team. As an audition, she offers to investigate the recently discovered bones of Tobi Turner, a high school girl who disappeared fifteen years ago. While investigating with local sheriff Mike Nevada, a former colleague and onetime lover, Macy discovers a link between Tobi’s case and several others that occurred around the same time as her disappearance.

One year ago, Lucy’s sister, Nicki, left to meet friends at a pub in Dublin and never came home. The third Irish woman to vanish inexplicably in as many years, the agony of not knowing what happened that night has turned Lucy’s life into a waking nightmare. So, she’s going to take matters into her own hands. Angela works as a paper-pusher in the Missing Persons Unit, but wants nothing more than to be a fully fledged member of An Garda Síochána, the Irish police force. With the investigation into the missing women stalled, she begins pulling on a thread that could break the case wide open.

At loose ends after the devastating death of her mother, Una Richardson responds to an advertisement for a ladies’ companion, a position that leads her into the wealthy, secluded world of Mrs. Elspeth McKenzie. But Elspeth's home isn’t the comforting haven it seems. Kathryn, her cold and bitter daughter, resents Una's presence. More disturbing is evidence suggesting two girls lived here before her.

When Mel receives an unexpected email from her oldest friend Abi, it brings back memories she thought she had buried forever. Their friendship belonged in the past. To those carefree days at university. But Abi is in trouble and needs Mel’s help, and she wants a place to stay. Just for a few days, while she sorts things out. It’s the least Mel can do. After all, friends look out for each other, don’t they?

Lara was seven when her birth mother died from a drug overdose. With no extended family to look after her, she was put into foster care. The care system failed Lara and now she is failing her son. Lara and her one-year-old son, Arthur, are brought to experienced foster carer, Cathy Glass, by their social worker. Lara has fled an abusive relationship and Arthur has suspected non-accidental injuries. Cathy must monitor Lara whenever she is with her son, day and night. She cannot let them out of her sight for a minute.

Alicia Berenson’s life is seemingly perfect. A famous painter married to an in-demand fashion photographer, she lives in a grand house with big windows overlooking a park in one of London’s most desirable areas. One evening, her husband, Gabriel, returns home late from a fashion shoot, and Alicia shoots him five times in the face and then never speaks another word. Alicia’s refusal to talk, or give any kind of explanation, turns a domestic tragedy into something far grander, a mystery that captures the public imagination and casts Alicia into notoriety.

When Chloe Davis was twelve, six teenage girls went missing in her small Louisiana town. By the end of the summer, her own father had confessed to the crimes and was put away for life, leaving Chloe and the rest of her family to grapple with the truth and try to move forward while dealing with the aftermath.