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Superbugs
- The Race to Stop an Epidemic
- Narrated by: Matt McCarthy
- Length: 7 hrs and 45 mins
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Publisher's summary
International best seller
"An amazing, informative book that changes our perspective on medicine, microbes and our future." (Siddhartha Mukherjee, MD, New York Times best-selling author of The Emperor of All Maladies)
A New York Times best-selling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs.
Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively listenable Superbugs, and the results will impact nothing less than the future of humanity.
Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more.
The proverbial ticking clock will keep listeners on the edge of their seats. Can Dr. McCarthy save the lives of his patients infected with the deadly bacteria, who have otherwise lost all hope?
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Critic reviews
USA Today Book Not to Miss
One of Book Authority‘s Best Public Health Books of All Time
"Written from the front lines in the battle against resistant microbes, Superbugs will educate and inspire all those concerned about the growing threat to individuals and society. McCarthy offers a fast paced, vivid narrative that grips the reader from the opening pages and never lets go." (Jerome Groopman, MD; Recanati Professor, Harvard Medical School; co-author of New York Times best seller Your Medical Mind)
"There might not be another author who so fluidly combines a world-class doctor and researcher’s knowledge and experience with a memoirist’s sensibility. Matt McCarthy is Siddhartha Mukherjee and David Sedaris rolled into one. Who else but McCarthy could write a dispatch from the front lines of the secret fight for the future of the human race that is not just gripping and illuminating, but also poignant and funny?" (Ben Reiter, New York Times best-selling author of Astroball)
"A riveting insider's look at the race to find a cure for antibiotic-resistant infections, one of the most pressing challenges in modern medicine.... The author's storytelling is at once urgent and empathetic, a compelling combination that leaves readers feeling informed and optimistic. Insightful and honest, McCarthy effectively combines useful information about the latest advances in microbial research with accounts of the best aspects of humanity." (Kirkus)
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In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.
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A must read
- By kara kuntz on 05-20-21
By: Jason Karlawish
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A Shot to Save the World
- The Inside Story of the Life-or-Death Race for a COVID-19 Vaccine
- By: Gregory Zuckerman
- Narrated by: Jack Armstrong
- Length: 12 hrs and 6 mins
- Unabridged
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Few were ready when a mysterious respiratory illness emerged in Wuhan, China, in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization.
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Wow! Do not miss this one.
- By Jacob on 11-18-21
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The Emperor of All Maladies
- A Biography of Cancer
- By: Siddhartha Mukherjee
- Narrated by: Fred Sanders
- Length: 22 hrs and 18 mins
- Unabridged
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The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".
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Incredible
- By S.R.E. on 03-02-16
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State of the Heart
- Exploring the History, Science, and Future of Cardiac Disease
- By: Haider Warraich
- Narrated by: Neil Shah
- Length: 11 hrs and 8 mins
- Unabridged
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In State of the Heart, the journey to rid the world of heart disease is shown to be reflective of the journey of medical science at large. We are learning not only that women have as much heart disease as men, but that the type of heart disease women experience is diametrically different from that in men. We are learning that heart disease and cancer may have more in common than we could have imagined. And we are learning how human evolution itself may have led to the epidemic of heart disease
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Good information, bad organization
- By Conor Cox on 09-03-19
By: Haider Warraich
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Less Medicine, More Health
- 7 Assumptions That Drive Too Much Medical Care
- By: H. Gilbert Welch
- Narrated by: L. J. Ganser
- Length: 8 hrs and 18 mins
- Unabridged
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The author of the highly acclaimed Overdiagnosed describes seven widespread assumptions that encourage excessive, often ineffective, and sometimes harmful medical care. You might think the biggest problem in medical care is that it costs too much. Or that health insurance is too expensive, too uneven, too complicated - and gives you too many forms to fill out. But the central problem is that too much medical care has too little value.
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The truth will set you free
- By Rene B Milner on 04-01-16
By: H. Gilbert Welch
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- By: Thomas Hager
- Narrated by: Angelo Di Loreto
- Length: 8 hrs and 39 mins
- Unabridged
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Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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Engrossing to physicians & lay persons alike
- By C. White on 03-08-19
By: Thomas Hager
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Heart
- A History
- By: Sandeep Jauhar
- Narrated by: Patrick Lawlor
- Length: 8 hrs and 43 mins
- Unabridged
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For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As cardiologist and best-selling author Sandeep Jauhar tells in The Heart, it was only recently that we demolished age-old taboos and devised the transformative procedures that changed the way we live. Deftly alternating between historical episodes and his own work, Jauhar tells the colorful and little known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ.
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Fascinating Insight
- By Ironcharles on 10-27-18
By: Sandeep Jauhar
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The Desperate Hours
- One Hospital's Fight to Save a City on the Pandemic's Front Lines
- By: Marie Brenner
- Narrated by: Kirsten Potter
- Length: 15 hrs and 41 mins
- Unabridged
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In the spring of 2020, COVID-19 arrived in New York City. Before long, America’s largest metropolis was at war against a virus that mercilessly swept through its five boroughs. In The Desperate Hours, award-winning journalist Marie Brenner, having been granted unprecedented 18-month access to the entire New York-Presbyterian hospital system, tells the story of the doctors, nurses, residents, researchers, and suppliers who tried to save lives across Manhattan, Queens, and Brooklyn and the northern periphery of the city.
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Way too much politics
- By Josh on 07-18-22
By: Marie Brenner
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God's Hotel
- A Doctor, a Hospital, and a Pilgrimage to the Heart of Medicine
- By: Victoria Sweet
- Narrated by: Victoria Sweet
- Length: 13 hrs and 44 mins
- Unabridged
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San Francisco's Laguna Honda Hospital is the last almshouse in the country, a descendant of the Hôtel-Dieu (God's hotel) that cared for the sick in the Middle Ages. Ballet dancers and rock musicians, professors and thieves - "anyone who had fallen, or, often, leapt, onto hard times" and needed extended medical care - ended up here. So did Victoria Sweet, who came for two months and stayed for 20 years. Laguna Honda, lower-tech but human-paced, gave Sweet the opportunity to practice a kind of attentive medicine that has almost vanished.
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Great read
- By kayla solomon on 04-08-17
By: Victoria Sweet
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Influenza
- The Hundred-Year Hunt to Cure the 1918 Spanish Flu Pandemic
- By: Dr. Jeremy Brown
- Narrated by: Holter Graham
- Length: 6 hrs and 28 mins
- Unabridged
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On the 100th anniversary of the devastating pandemic of 1918, Jeremy Brown, a veteran ER doctor, explores the troubling, terrifying, and complex history of the flu virus, from the origins of the Great Flu that killed millions, to vexing questions such as: are we prepared for the next epidemic, should you get a flu shot, and how close are we to finding a cure?
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Important read
- By Kathryn C. on 12-21-18
By: Dr. Jeremy Brown
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Plague of Corruption
- Restoring Faith in the Promise of Science
- By: Dr. Judy Mikovits, Kent Heckenlively, Robert F. Kennedy Jr.
- Narrated by: Mariel Hemingway
- Length: 10 hrs and 10 mins
- Unabridged
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Dr. Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys' club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried.
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If only most of the public knew these facts
- By David Getoff, CCN on 06-18-20
By: Dr. Judy Mikovits, and others
What listeners say about Superbugs
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Robert Edward Price
- 02-26-21
Excellent 👌
Dr. McCarthy nails the balance between compellingingly human and groundbreaking clinical medicine by walking us through his "translational" research with Dalba. At the same time, by celebrating the clear brilliance of Dr. Walsh whose work has prevented countless deaths to infection he also puts to the page an ode to the experienced mind in medicine that will always have it's place among the latest and greatest antibiotics since those hard-earned drugs will only be so powerful as those who wield their powers. If more doctors in training would read this book I believe both over prescription and white-coated pride could be prevented in a large degree. In any case, an excellent read. Thanks Dr. McCarthy.
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- Elaine
- 06-16-20
Not a scientific book
A good book of the backstory of bringing a new drug to market. Interesting read.
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- Rebecca B. Clark
- 07-16-19
Beyond Clinical Competence
The clinical challenges of fighting superbugs makes for a compelling listen. But the hidden gift of this book is its focus on Tom Walsh, the author’s mentor. Walsh is an energetic polymath whose insight and expertise bring hope to hopeless cases, yet his relentless optimism can’t prevent him from absorbing the pain of suffering patients. Matt McCarthy reveals what Tom Walsh has taught him along the way: patience, humility, curiosity, and unflinching dedication to the mission of helping the helpless.
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2 people found this helpful
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LOVED IT !
I couldn't stop listening. It elicited so many memories of good and bad. Thank you for writing the book.
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1 person found this helpful
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- RubErDuckee
- 08-02-19
Excellent, well written depiction of superbugs
I was nerding out the whole time! As a Laboratory Scientist this was an easy book to follow, and I would recommend it to anyone that is in the medical field. I also think it would be great for people that are curious about the world of antibiotics and treatment for bacteria, fungus etc. The author does a phenomenal job of bringing the history of antibiotics and superbugs. I thoroughly enjoyed this one!
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- Amazon Customer
- 12-01-19
The humanity of medicine & research
I liked the author's other book, The Real Doctor Will See You Shortly, a lot too. I'm a medical student interested in research and infectious disease, so I learned a lot about history and development of bugs and drugs through this story. I always appreciate gaining insight into life in medicine and the humanity and ethics of healthcare.
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- Hans Rigelman
- 09-30-21
A Very Personal Look at the War on Superbugs
Matt McCarthy tells a very real story about his patients and their personal battles against some very nasty bacterial infections that prove to be resistant to the more common antibiotics used to fight them. This story is far from over.
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- Rebecca
- 07-25-19
Fascinating/Scary
Informative as to the processes of developing a new drug, fascinating because of the patient experiences and scary because bacteria can hurt us so badly. I appreciate people like the author who strive to find answers.
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- Semper Curiosus
- 09-16-20
Terrific even as somebody in medicine.
I’m always hesitant to start a book that might be targeted to the general public but after “The Real Doctor Will See You Shortly” I had hope. It was not misplaced; this book was excellent as a soon to be physician. I’ve heard some of it before but I appreciated the historical aspects and clinical wisdom of trials that I definitely wouldn’t get anywhere else.
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- India Clamp
- 07-23-19
Brilliant read by Dr. Matt McCarthy!
This is not my first book review of Author/MD/Assistant Professor of Medicine Matt McCarthy and given his content I will persevere to review additional literary orchestrations as they are never trite. If virology is your “chocolate fix” then “Superbugs: The Race to Stop an Epidemic” is the signal to “Graviora manent.”
The question is what always motivates the genius. In this case a decade was spent in a lab as Little Flem asked himself, “How did bacteria thrive and how could they be killed?” Not quite the Nobel prize winner (yet) we meet---via Dr. McCarthy---Alexander Fleming in his humble days as a “triage medic” transporting dead and dying patients.
“...Little Flem as he was known, was not drawn to controversy, or to combat or even a conversation. (One colleague claimed that trying to speak to him was like playing tennis with a man who, when he received a serve, put the ball in his pocket.)”
---Matt McCarthy, MD
Knowledge brings sadness and the question “Why?" Confronted with wisdom that not all physicians act on behalf of patients. Recount of the Tuskegee study is given. Eighty two percent were black and twenty-two percent could not read or write. What must it be like to do 20 spinal taps on a quotidian basis and watch suffering men with syphilis?
"Superbugs: The Race to Stop an Epidemic” is on the level of literary star “Siddhartha Mukherjee, MD” in originality and brevity. Dr. Matt McCarthy opens wide the doors to a brilliant introvert and Nobel Prize winner Sir Alexander Fleming---who engineered the drug penicillin. He adored music. Sad, realistic and honest. Buy and read.
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2 people found this helpful