The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

The runaway success of the microchip may finally be reaching its end. As shrinking transistors approach the size of atoms, the phenomenal growth of computational power inevitably collapses. But this change heralds the birth of a revolutionary new type of computer, one that calculates on atoms themselves. Quantum computers promise unprecedented gains in computing power, enabling advancements that could overturn every aspect of our daily lives.

In a rarified world of scientific research, a revolution has been brewing. Its activists are not anarchists, but rather Nobel Laureates in physics and economics and pony-tailed graduates, mathematicians, and computer scientists from all over the world. They have formed an iconoclastic think-tank and their radical idea is to create a new science: complexity. They want to know how a primordial soup of simple molecules managed to turn itself into the first living cell--and what the origin of life some four billion years ago can tell us about the process of technological innovation today.

For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.

From legendary investor Ray Dalio, author of the number-one New York Times best seller Principles, who has spent half a century studying global economies and markets, Principles for Dealing with the Changing World Order examines history’s most turbulent economic and political periods to reveal why the times ahead will likely be radically different from those we’ve experienced in our lifetimes - and to offer practical advice on how to navigate them well.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

The term metaverse is suddenly everywhere, from debates over Fortnite to the pages of the New York Times to the speeches of Mark Zuckerberg, who proclaimed in June 2021 that “the overarching goal” of Facebook is to “bring the metaverse to life”. But what, exactly, is the metaverse? As pioneering theorist and venture capitalist Matthew Ball explains, it is the successor to the mobile internet that has defined the last two decades.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

The father of three sons, a journalist, and a Brookings Institution scholar, Richard V. Reeves has spent twenty-five years worrying about boys both at home and work. His new book, Of Boys and Men, tackles the complex and urgent crisis of boyhood and manhood. Reeves looks at the structural challenges that face boys and men and offers fresh and innovative solutions that turn the page on the corrosive narrative that plagues this issue. Of Boys and Men argues that helping the other half of society does not mean giving up on the ideal of gender equality.

Whether pondering black holes or predicting discoveries at CERN, physicists believe the best theories are beautiful, natural, and elegant, and this standard separates popular theories from disposable ones. This is why, Sabine Hossenfelder argues, we have not seen a major breakthrough in the foundations of physics for more than four decades. The belief in beauty has become so dogmatic that it now conflicts with scientific objectivity: Observation has been unable to confirm mindboggling theories, like supersymmetry or grand unification, invented by physicists based on aesthetic criteria.

Challenging leading scientific theories that claim that our senses report back objective reality, cognitive scientist Donald Hoffman argues that while we should take our perceptions seriously, we should not take them literally. How can it be possible that the world we see is not objective reality? And how can our senses be useful if they are not communicating the truth? Hoffman grapples with these questions and more over the course of this eye-opening work.

For generations, everything has been getting faster, better, and cheaper. Finally, we reached the point that almost anything you could ever want could be sent to your home within days - even hours - of when you decided you wanted it. America made that happen, but now America has lost interest in keeping it going.

You may be surprised to learn that microchips are the new oil—the scarce resource on which the modern world depends. Today, military, economic, and geopolitical power are built on a foundation of computer chips. Virtually everything—from missiles to microwaves—runs on chips, including cars, smartphones, the stock market, even the electric grid. Until recently, America designed and built the fastest chips and maintained its lead as the #1 superpower, but America’s edge is in danger of slipping, undermined by players in Taiwan, Korea, and Europe taking over manufacturing.

Oxygen takes the listener on an enthralling journey, as gripping as a thriller, as it unravels the unexpected ways in which oxygen spurred the evolution of life and death.

Jim Simons is the greatest money maker in modern financial history. No other investor - Warren Buffett, Peter Lynch, Ray Dalio, Steve Cohen, or George Soros - can touch his record. Since 1988, Renaissance's signature Medallion fund has generated average annual returns of 66 percent. The firm has earned profits of more than $100 billion; Simons is worth 23 billion dollars.

Biomimicry is rapidly transforming life on earth. Biomimics study nature's most successful ideas over the past 3.5 million years, and adapt them for human use. The results are revolutionizing how materials are invented and how we compute, heal ourselves, repair the environment, and feed the world. Janine Benyus takes listeners into the lab and in the field with maverick thinkers as they: discover miracle drugs by watching what chimps eat when they're sick; learn how to create by watching spiders weave fibers; and many more examples.

What is life? Humans have been asking this question for thousands of years. But as technology has advanced and our understanding of biology has deepened, the answer has evolved. For decades, scientists have been exploring the limits of nature by modifying and manipulating DNA, cells, and whole organisms to create new ones that could never have previously existed on their own.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

Space entrepreneur turned innovation pioneer Peter H. Diamandis and award-winning science writer Steven Kotler document how progress in artificial intelligence, robotics, digital manufacturing synthetic biology, and other exponentially growing technologies will enable us to make greater gains in the next two decades than we have in the previous 200 years.

K. Eric Drexler is the founding father of nanotechnology - the science of engineering on a molecular level. In Radical Abundance, he shows how rapid scientific progress is about to change our world. Thanks to atomically precise manufacturing, we will soon have the power to produce radically more of what people want, and at a lower cost. The result will shake the very foundations of our economy and environment.

New York Times, Wired, Atlantic Monthly, Discover bestselling author Steven Kotler has written extensively about those pivotal moments when science fiction became science fact...and fundamentally reshaped the world. Now he gathers the best of his best, updated and expanded upon, to guide listeners on a mind-bending tour of the far frontier, and how these advances are radically transforming our lives.

Paul Falkowski looks "under the hood" of microbes to find the engines of life, the actual working parts that do the biochemical heavy lifting for every living organism on Earth. With insight and humor, he explains how these miniature engines are built - and how they have been appropriated by and assembled like Lego sets within every creature that walks, swims, or flies. Falkowski shows how evolution works to maintain this core machinery of life, and how we and other animals are veritable conglomerations of microbes.

Scientific developments radically alter our understanding of the world. Whether it's technology, climate change, health research, or the latest revelations of neuroscience, physics, or psychology, science has, as Edge editor John Brockman says, "become a big story, if not the big story". In that spirit this new addition to Edge.org's fascinating series asks a powerful and provocative question: What do you consider the most interesting and important recent scientific news?

In this smart and funny book, celebrated cartoonist Zach Weinersmith and noted researcher Dr. Kelly Weinersmith give us a snapshot of what's coming next - from robot swarms to nuclear fusion powered-toasters. By weaving their own research and interviews with the scientists who are making these advances happen, the Weinersmiths investigate why these technologies are needed, how they would work, and what is standing in their way.

This new book by Spencer Wells, the internationally known geneticist, anthropologist, author, and director of the Genographic Project, focuses on the seminal event in human history: mankind's decision to become farmers rather than hunter-gatherers.

The hazards of electronic pollution may once have been the stuff of science fiction, but now we know they're all too real. And with the advent of 5G ultra-wideband technology, the danger is greater than ever. Dr. Joseph Mercola, one of the world's foremost authorities on alternative health, has mined the scientific literature to offer a radical new understanding of how electromagnetic fields impact your body and mind.

The human brain is perhaps the most powerful and mysterious arrangement of matter in the known universe. New discoveries that unravel this mystery and let us tap into this power offer almost limitless potential - the ability to reshape ourselves and our thought processes, to improve our health and extend our lives, and to enhance and augment the ways we interact with the world around us. In The NeuroGeneration, award-winning inventor Tan Le explores exciting advancements in brain science and neurotechnology that are revolutionizing the way we think, work, and heal.

Engrossing and captivating, Editing Humanity takes listeners inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces listeners to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.

Today, not only is everything digital getting faster, cheaper, and smaller at an exponential rate, we also have the Internet. When these two revolutions - one in technology and the other in communications - joined, an explosive force was unleashed that changed the very nature of innovation. And with any change, we have seen many strategic blunders and extraordinary learning curves along the way.

The Earth teems with life: in its oceans, forests, skies, and cities. Yet there's a black hole at the heart of biology. We do not know why complex life is the way it is, or, for that matter, how life first began. In The Vital Question, award-winning author and biochemist Nick Lane radically reframes evolutionary history, putting forward a solution to conundrums that have puzzled generations of scientists.