Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

After Englishman John Blackthorne is lost at sea, he awakens in a place few Europeans know of and even fewer have seen—Nippon. Thrust into the closed society that is seventeenth-century Japan, a land where the line between life and death is razor-thin, Blackthorne must negotiate not only a foreign people, with unknown customs and language, but also his own definitions of morality, truth, and freedom. As internal political strife and a clash of cultures lead to seemingly inevitable conflict, Blackthorne’s loyalty and strength of character are tested by both passion and loss.

In this smart and funny book, celebrated cartoonist Zach Weinersmith and noted researcher Dr. Kelly Weinersmith give us a snapshot of what's coming next - from robot swarms to nuclear fusion powered-toasters. By weaving their own research and interviews with the scientists who are making these advances happen, the Weinersmiths investigate why these technologies are needed, how they would work, and what is standing in their way.

It’s 1965 and teenage Frances Adams is at an English country fair with her two best friends. But Frances’s night takes a hairpin turn when a fortune-teller makes a bone-chilling prediction: One day, Frances will be murdered. Frances spends a lifetime trying to solve a crime that hasn’t happened yet, compiling dirt on every person who crosses her path in an effort to prevent her own demise. For decades, no one takes Frances seriously, until nearly sixty years later, when Frances is found murdered, like she always said she would be.

Cosmos is one of the bestselling science books of all time. In clear-eyed prose, Sagan reveals a jewel-like blue world inhabited by a life form that is just beginning to discover its own identity and to venture into the vast ocean of space.

From launchpad explosions to a pernicious cricket infestation to the demanding management style of Musk himself, the rise of SpaceX was beset with challenges and far from inevitable. Find out how the startup beat the odds and flew high enough to outpace their rivals... and where they're going next.

A Zoo in My Luggage is the colorful, first-hand account of Gerald Durrell's six-month animal-collecting trip in British Cameroon, and his attempts to create his own zoo. Motivated by a passion for wildlife, and a desire to save endangered species from extinction, Durrell assembles a glorious panoply of exotic animals - including a female baboon called Georgina, who later runs amok in a department store; a black-eared squirrel, who tries to bury nuts in his ear; and a gentlemanly chimpanzee named Chumly, who greets him with an outstretched hand.

The Republic is perhaps the single most important, the most studied and the most quoted text of all of Plato's Socratic Dialogues. Through the medium of Socrates, Plato outlines his view and ideas concerning the ideal working of the city-state. Socrates narrates a conversation that took place the previous day with Cephalus, Glaucon, Thrasymachus and others. The dialogue is organised into 10 books and covers a broad range of topics, including the ideal community and the ideal rulers of the community.

In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and more.

What is the nature of space and time? How do we fit within the universe? How does the universe fit within us? There's no better guide through these mind-expanding questions than acclaimed astrophysicist and best-selling author Neil deGrasse Tyson. But today, few of us have time to contemplate the cosmos. So Tyson brings the universe down to Earth succinctly and clearly, with sparkling wit, in digestible chapters consumable anytime and anywhere in your busy day.

My Big TOE: Awakening, written by a nuclear physicist in the language of contemporary culture, unifies science and philosophy, physics and metaphysics, mind and matter, purpose and meaning, the normal and the paranormal. The entirety of human experience (mind, body, and spirit) including both our objective and subjective worlds is brought together under one seamless scientific understanding.

Chemistry and Our Universe: How It All Works is your in-depth introduction to this vital field, taught through 60 engaging half-hour lectures that are suitable for any background or none at all. Covering a year’s worth of introductory general chemistry at the college level, plus intriguing topics that are rarely discussed in the classroom, this amazingly comprehensive course requires nothing more advanced than high-school math. Your guide is Professor Ron B. Davis, Jr., a research chemist and award-winning teacher at Georgetown University.

Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.

How the Earth Works takes you on an astonishing journey through time and space. In 48 lectures, you will look at what went into making our planet - from the big bang, to the formation of the solar system, to the subsequent evolution of Earth.

We are in the midst of a global mental health crisis, and mental illnesses are on the rise. But what causes mental illness? And why are mental health problems so hard to treat? Drawing on decades of research, Harvard psychiatrist Dr. Chris Palmer outlines a revolutionary new understanding that for the first time unites our existing knowledge about mental illness within a single framework: mental disorders are metabolic disorders of the brain. Brain Energy will transform the field of mental health, and the lives of countless people around the world.

Welcome to the Universe is a personal guided tour of the cosmos by three of today's leading astrophysicists. Inspired by the enormously popular introductory astronomy course that Neil deGrasse Tyson, Michael A. Strauss, and J. Richard Gott taught together at Princeton, this book covers it all - from planets, stars, and galaxies to black holes, wormholes, and time travel.

Hilarious, fascinating, and a roller coaster of dizzying, historical what-ifs, Napoleon's Hemorrhoids is a potpourri for serious historians and casual history buffs. In one of Phil Mason's many revelations, you'll learn that Communist jets were two minutes away from opening fire on American planes during the Cuban missile crisis, when they had to turn back as they were running out of fuel. You'll discover that before the Battle of Waterloo, Napoleon's painful hemorrhoids prevented him from mounting his horse to survey the battlefield.

Dr. Catherine Kleier invites us to open our eyes to the phenomenal world of plant life and to the process she calls “Natura Revelata”, the joy of celebrating and learning from the secrets of nature. As Dr. Kleier shares her knowledge with contagious excitement for her subject, she emphasizes the middle ground: Instead of focusing on cell microbiology or the study of ecosystems and habitats, she stresses the basic biology, function, and the amazing adaptations of the plants we see all around us.

From launchpad explosions to a pernicious cricket infestation to the demanding management style of Musk himself, the rise of SpaceX was beset with challenges and far from inevitable. Find out how the startup beat the odds and flew high enough to outpace their rivals... and where they're going next.

One of the most complicated and advanced computers on Earth can't be purchased in any store. This astonishing device, responsible for storing and retrieving vast quantities of information that can be accessed at a moment's notice, is the human brain. How does such a dynamic and powerful machine make memories, learn a language, and remember how to drive a car? What habits can we adopt in order to learn more effectively throughout our lives? The answers to these questions are merely the tip of the iceberg in The Learning Brain.

Bill Bryson once again proves himself to be an incomparable companion as he guides us through the human body - how it functions, its remarkable ability to heal itself, and (unfortunately) the ways it can fail. Full of extraordinary facts (your body made a million red blood cells since you started reading this) and irresistible Bryson-esque anecdotes, The Body will lead you to a deeper understanding of the miracle that is life in general and you in particular. As Bill Bryson writes, "We pass our existence within this wobble of flesh and yet take it almost entirely for granted."

In Made in America, Bryson de-mythologizes his native land, explaining how a dusty hamlet with neither woods nor holly became Hollywood, how the Wild West wasn't won, why Americans say 'lootenant' and 'Toosday', how Americans were eating junk food long before the word itself was cooked up, as well as exposing the true origins of the G-string, the original $64,000 question, and Dr Kellogg of cornflakes fame.

In the first of three essays included in this audiobook, Bill Bryson decides to move his wife and kids back to his homeland, the United States, after nearly two decades in Britain. But not before taking one last trip around Britain, a sort of valedictory tour of the green and kindly island that had so long been his home. The result is a hilarious social commentary.

Designed for non-scientists, Six Easy Pieces is an unparalleled introduction to the world of physics by one of the greatest teachers of all time.

Superintelligence asks the questions: What happens when machines surpass humans in general intelligence? Will artificial agents save or destroy us? Nick Bostrom lays the foundation for understanding the future of humanity and intelligent life. The human brain has some capabilities that the brains of other animals lack. It is to these distinctive capabilities that our species owes its dominant position. If machine brains surpassed human brains in general intelligence, then this new superintelligence could become extremely powerful - possibly beyond our control.

Christmas is the single biggest annual event on the planet, a time for merry-making, over-indulgence, peace, goodwill, and the occasional family row. It’s as comfortable and familiar as a pair of old shoes and yet still glittery and exciting. But what do you really know about it? It’s stuffed full of traditions and rituals that most of us have been observing all our lives without having the slightest idea of where they come from.

The latest groundbreaking tome from Tim Ferriss, the number-one New York Times best-selling author of The 4-Hour Workweek. For the last two years, I've interviewed more than 200 world-class performers for my podcast, The Tim Ferriss Show. The guests range from super celebs (Jamie Foxx, Arnold Schwarzenegger, etc.) and athletes (icons of powerlifting, gymnastics, surfing, etc.) to legendary Special Operations commanders and black-market biochemists. For most of my guests, it’s the first time they’ve agreed to a two-to-three-hour interview.

Today's "machine-learning" systems, trained by data, are so effective that we've invited them to see and hear for us - and to make decisions on our behalf. But alarm bells are ringing. Systems cull résumés until, years later, we discover that they have inherent gender biases. Algorithms decide bail and parole - and appear to assess black and white defendants differently. We can no longer assume that our mortgage application, or even our medical tests, will be seen by human eyes. And autonomous vehicles on our streets can injure or kill.

In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and more.

From the celebrated neurobiologist and primatologist, a landmark, genre-defining examination of human behavior, both good and bad, and an answer to the question: Why do we do the things we do? Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: He starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its evolutionary legacy.

From an acclaimed Harvard professor and one of Time’s most influential people, this paradigm-shifting audiobook shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls listeners to consider a future where aging can be treated.

Robert Sapolsky’s Behave, his now classic account of why humans do good and why they do bad, pointed toward an unsettling conclusion: We may not grasp the precise marriage of nature and nurture that creates the physics and chemistry at the base of human behavior, but that doesn’t mean it doesn’t exist. Now, in Determined, Sapolsky takes his argument all the way, mounting a brilliant (and in his inimitable way, delightful) full-frontal assault on the pleasant fantasy that there is some separate self telling our biology what to do.

Having done field work in New Guinea for more than 30 years, Jared Diamond presents the geographical and ecological factors that have shaped the modern world. From the viewpoint of an evolutionary biologist, he highlights the broadest movements both literal and conceptual on every continent since the Ice Age, and examines societal advances such as writing, religion, government, and technology.

How did Fidel Castro fool the CIA for a generation? Why did Neville Chamberlain think he could trust Adolf Hitler? Why are campus sexual assaults on the rise? Do television sitcoms teach us something about the way we relate to each other that isn't true? While tackling these questions, Malcolm Gladwell was not solely writing a book for the page. He was also producing for the ear. In the audiobook version of Talking to Strangers, you’ll hear the voices of people he interviewed - scientists, criminologists, military psychologists.

"While the history books are filled with tales of obsessive visionary geniuses who remade the world in their images with sheer, almost irrational force, I've found that history is also made by individuals who fought their egos at every turn, who eschewed the spotlight, and who put their higher goals above their desire for recognition." (From the prologue)