The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".

Even more relevant than when it was first published, this edition addresses contemporary issues in end-of-life care and includes an all-embracing and incisive afterword that examines the state of health care and our relationship with life as it approaches its terminus. How We Die also discusses how we can take control of our own final days and those of our loved ones.

A riveting exploration of the most difficult and important part of what doctors do, by Yale School of Medicine physician Dr. Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis", the inspiration for the hit Fox TV series House, M.D. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.

Understanding our humanity - the essence of who we are - is one of the deepest mysteries and biggest challenges in modern science. Why do we have bad moods? Why are we capable of having such strange dreams? How can metaphors in our language hold such sway on our actions? As we learn more about the mechanisms of human behavior through evolutionary biology, neuroscience, anthropology, and other related fields, we're discovering just how intriguing the human species is.

A work of great personal courage and a literary tour de force, this bestseller is Styron's true account of his experience of crippling depression. Styron is perhaps the first writer to convey the full terror of depression's psychic landscape, as well as the illuminating path to recovery.

At the age of 27, married, living in New York, and working in book design, Mary Cregan gives birth to her first child, a daughter she names Anna. But it’s apparent that something is terribly wrong, and two days later, Anna dies - plunging Cregan into suicidal despair. Decades later, sustained by her work, a second marriage, and a son, Cregan reflects on this pivotal experience and attempts to make sense of it. She weaves together literature and research with details from her own ordeal - and the still visible scar of her suicide attempt....

Does time exist? What is infinity? Why do mirrors reverse left and right but not up and down? In this scintillating collection, Holt explores the human mind, the cosmos, and the thinkers who’ve tried to encompass the latter with the former. With his trademark clarity and humor, Holt probes the mysteries of quantum mechanics, the quest for the foundations of mathematics, and the nature of logic and truth. Along the way, he offers intimate biographical sketches of celebrated and neglected thinkers, from the physicist Emmy Noether to the computing pioneer Alan Turing and the discoverer of fractals, Benoit Mandelbrot.

The Naked Communist has sold almost two million copies. It found its way into the libraries of the CIA, the FBI, the White House, and homes all across America and the world. The Naked Communist contains a distillation of more than a hundred books and treatises on communism, many written by Marxist authors. We see the communist the way he sees himself - stripped of propaganda and pretense. Explained here is the amazing appeal of communism, its history, and its basic and unchanging concepts.

In this major statement, the renowned international-relations scholar John Mearsheimer argues that liberal hegemony, the foreign policy pursued by the United States since the Cold War ended, is doomed to fail. It makes far more sense, he maintains, for Washington to adopt a more restrained foreign policy based on a sound understanding of how nationalism and realism constrain great powers abroad.

In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.

Why was gin and tonic the cocktail of choice for British colonists in India and Africa? What does Starbucks have to thank for its global domination? What has protected the lives of popes for millennia? Why did Scotland surrender its sovereignty to England? What was George Washington's secret weapon during the American Revolution? The answer to all these questions, and many more, is the mosquito. Driven by surprising insights and fast-paced storytelling, The Mosquito is the extraordinary untold story of the mosquito’s reign through human history.

This is a thrilling historical account of the worst cholera outbreak in Victorian London and a brilliant exploration of how Dr. John Snow's solution revolutionized the way we think about disease, cities, science, and the modern world.

In the winter of 1918, at the height of World War I, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 weeks than AIDS has killed in 24 years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision between modern science and epidemic disease.

The Great War of 1914-1918 burst on the European scene with a brutality to mankind not yet witnessed by the civilized world. Modern warfare was no longer the stuff of chivalry and honor; it was a mutilative, deadly, and humbling exercise to wipe out the very presence of humanity. Suddenly, thousands upon thousands of maimed, beaten, and bleeding men surged into aid stations and hospitals with injuries unimaginable in their scope and destruction. Doctors scrambled to find some way to salvage not only life but limb.

Plagues upon the Earth is a monumental history of humans and their germs. Weaving together a grand narrative of global history with insights from cutting-edge genetics, Kyle Harper explains why humanity’s uniquely dangerous disease pool is rooted deep in our evolutionary past, and why its growth is accelerated by technological progress. He shows that the story of disease is entangled with the history of slavery, colonialism, and capitalism, and reveals the enduring effects of historical plagues all around us, in patterns of wealth, health, power, and inequality.

In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB - often called consumption - was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy - a remedy that would be his undoing. When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event.

In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.

Praised for his erudite writing, renowned scientist Frank Gonzalez-Crussi penned this concise history of medicine, beginning with the most primitive health-care practices and ending with the technology of modern medicine that we enjoy today. As with all Modern Library Chronicles, A Short History of Medicine is a wonderful primer for anyone interested in the subject.

Written by an author with plenty of experience holding a scalpel, Dr. David Schneider's in-depth biography is an encompassing history of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing implant revolution of the 20th century.

In The Knife Man, Wendy Moore unveils John Hunter's murky and macabre world - a world characterized by public hangings, secret expeditions to dank churchyards, and gruesome human dissections in pungent attic rooms. This is a fascinating portrait of a remarkable pioneer and his determined struggle to haul surgery out of the realms of meaningless superstitious ritual and into the dawn of modern medicine.

Elinor Cleghorn became an unwell woman 10 years ago. She was diagnosed with an autoimmune disease after a long period of being told her symptoms were anything from psychosomatic to a possible pregnancy. As Elinor learned to live with her unpredictable disease, she turned to history for answers, and found an enraging legacy of suffering, mystification, and misdiagnosis. In Unwell Women, Elinor Cleghorn traces the almost unbelievable history of how medicine has failed women by treating their bodies as alien and other, often to perilous effect.

In the winter of 1918, at the height of World War I, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 weeks than AIDS has killed in 24 years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision between modern science and epidemic disease.

Galen of Pergamum (A.D. 129-ca. 216) began his remarkable career tending to wounded gladiators in provincial Asia Minor. Later in life he achieved great distinction as one of a small circle of court physicians to the family of Emperor Marcus Aurelius, at the very heart of Roman society. Susan Mattern's The Prince of Medicine offers the first authoritative biography in English of this brilliant, audacious, and profoundly influential figure.

Important and provocative, The Undead examines why even with the tools of advanced technology, what we think of as life and death, consciousness and nonconsciousness, is not exactly clear - and how this problem has been further complicated by the business of organ harvesting.

From evolution to the epidural and beyond, Tina Cassidy presents an intelligent, enlightening, and impeccably researched cultural history of how and why we're born the way we are. Women have been giving birth for millennia, but that's about the only constant in the final stage of the great process that is human reproduction. Why is it that every culture and generation seems to have its own ideas about the best way to give birth?

The Panic Virus is a gripping scientific detective story about how grassroots radicals, snake-oil salesmen, and cynical journalists have perpetrated the biggest health-scare hoax of all time. It explores what happens when the media treats all viewpoints as equally valid, regardless of facts, from parents who are convinced that vaccines caused their children's autism to right-wing radicals who believe that climate change is a myth

In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.

On average, a physician will interrupt a patient describing her symptoms within 12 seconds. In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong: with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make.

At one time heart disease was a death sentence. By the middle of the 20th century, it was killing millions, and, as with the Black Death centuries before, physicians stood helpless. Visionaries, though, had begun to make strides earlier. On September 7, 1895, Ludwig Rehn successfully sutured the heart of a living man with a knife wound to the chest for the first time.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

Antoine Lavoisier reinvented chemistry, overthrowing the long-established principles of alchemy and inventing an entirely new terminology, one still in use by chemists. Madison Smartt Bell’s enthralling narrative comes across like a race to the finish line, as the very circumstances that enabled Lavoisier to secure his reputation as the father of modern chemistry—a considerable fortune and social connections with the likes of Benjamin Franklin—also caused his glory to be cut short by the French Revolution.

Now published in five languages, Strange Medicine casts a gimlet eye on the practice of medicine through the ages that highlights the most dubious ideas, bizarre treatments, and biggest blunders. From bad science and oafish behavior to stomach-turning procedures that hurt more than helped, Strange Medicine presents strange but true facts and an honor roll of doctors, scientists, and dreamers who inadvertently turned the clock of medicine backward.

John Roebling was one of the 19th century's most brilliant engineers, ingenious inventors, successful manufacturers, and fascinating personalities. Raised in a German backwater amid the war-torn chaos of the Napoleonic Wars, he immigrated to the US in 1831, where he became wealthy and acclaimed, eventually receiving a carte-blanche contract to build one of the 19th century's most stupendous and daring works of engineering: a gigantic suspension bridge to span the East River between New York and Brooklyn.

In 1938, a young German rocket enthusiast named Wernher von Braun had dreams of building a rocket that could fly him to the moon. In Ray, North Dakota, a young farm girl named Mary Sherman was attending high school. In an age when girls rarely dreamed of a career in science, Mary wanted to be a chemist. A decade later, the dreams of these two disparate individuals would coalesce in ways neither could have imagined.

Most stories of medical progress come with ready-made heroes. John Snow traced the origins of London's 1854 cholera outbreak to a water pump, leading to the birth of epidemiology. Florence Nightingale's contributions to the care of soldiers in the Crimean War transformed hospitals from crucibles of infection to sanctuaries of recuperation. Yet histories of individual innovators ignore many key sources of medical knowledge.