For 14-year-old Wallis Ann Stamper and her family, life in the Appalachian Mountains is simple and satisfying, though not for the tenderhearted. While her older sister, Laci - a mute, musically gifted savant - is constantly watched over and protected, Wallis Ann is as practical and sturdy as her name. When the Tuckasegee River bursts its banks, forcing them to flee in the middle of the night, those qualities save her life. But though her family is eventually reunited, the tragedy opens Wallis Ann's eyes to a world beyond the creek that's borne their name for generations.

During the Great Depression, labor camps crop up in remote areas throughout the American South. Destitute workers live under terrible conditions. Trapped in these isolated locations, workers are entirely dependent on the often greedy, abusive camp owners who provide food and housing at grossly inflated prices. But for the most desperate among America's vast unemployed, these camps are often the last and only option.

Generations of Sassers have made moonshine in the Brushy Mountains of Wilkes County, North Carolina. Their history is recorded in a leather-bound journal that belongs to Jessie Sasser's daddy, but Jessie wants no part of it. As far as she's concerned, moonshine caused her mother's death a dozen years ago. Her father refuses to speak about her mama, or about the day she died. But Jessie has a gnawing hunger for the truth - one that compels her to seek comfort in food.

In 1969 Dixie Dupree is 11 years old and already an expert liar. Sometimes the lies are for her mama Evie's sake - to explain away a bruise brought on by her quick-as-lightning temper. And sometimes the lies are to spite Evie, who longs to leave her unhappy marriage in Perry County, Alabama, and return to her beloved New Hampshire. But for Dixie and her brother, Alabama is home, a place of pine-scented breezes and hot, languid afternoons.

Growing up on their hardscrabble farm in rural Kentucky, 15-year-old Albertina "Bertie" Winslow has learned a lot from her mama, Polly. She knows how to lance a boil, make a pie crust, butcher a pig, and tend to every chore that needs doing. What she doesn't know, but is forced to reckon with all too soon, is how to look after children as a mother should. When Polly succumbs to a long illness, Bertie takes on responsibility for her four younger siblings and their dissolute, unreliable daddy.

In a North Carolina mountain town filled with moonshine and rotten husbands, Sadie Blue is only the latest girl to face a dead-end future at the mercy of a dangerous drunk. She's been married to Roy Tupkin for 15 days, and she knows now that she should have listened to the folks who said he was trouble. But when a stranger sweeps in and knocks the world off-kilter for everyone in town, Sadie begins to think there might be more to life than being Roy's wife.

In the ruggedness of the beautiful Kentucky mountains, Honey Lovett has always known that the old ways can make a hard life harder. As the daughter of the famed blue-skinned Troublesome Creek packhorse librarian, Honey and her family have been hiding from the law all her life. But when her mother and father are imprisoned, Honey realizes she must fight to stay free, or risk being sent away for good.

"The dead can't hurt you. Only the living can." Effie Jones, a former slave who escaped to the Union side as a child, knows the truth of her words. Taken in by an army surgeon and his wife during the War, she learned to read and write, to tolerate the sight of blood and broken bodies - and to forget what is too painful to bear. Now a young freedwoman, she has returned south to New Orleans and earns her living as an embalmer, her steady hand and skillful incisions compensating for her white employer's shortcomings.

Magnolia, South Carolina, 1980: Austin Foster is barely a teenager when her mama dies giving birth to twins, leaving her to pick up the pieces while holding her six siblings together and doing her best to stop her daddy from retreating into his personal darkness.

Early one morning in 1929, Mary Seneca Steele spontaneously packs a suitcase, gathers up her son and daughter, and drives away in her abusive and dissolute husband’s brand-new Auburn Phaeton automobile, leaving her privileged life in Charleston behind. It is the beginning of a journey of enlightenment that leads Mary “Sen” to the mountains and mysteries of Appalachia, where she will learn unexpected family secrets, create a new life for herself and her children, and finally experience love and happiness before tragedy will once again test her.

It was 1970 when thirteen-year-old runaway Kit Walker was abducted by Manny Romero, a smooth-talking, low-level criminal, who first coddled her and then groomed her into his partner-in-crime. Before long, Kit and Manny were infamous for their string of gas station robberies throughout Texas, making a name for themselves as the Texaco Twosome.

It's 1924 in Branchville, South Carolina, and three women have come to a crossroads. Gertrude, a mother of four, must make an unconscionable decision to save her daughters. Retta, a first-generation freed slave, comes to Gertrude's aid by watching her children, despite the gossip it causes in her community. Annie, the matriarch of the influential Coles family, offers Gertrude employment at her sewing circle, while facing problems of her own at home.

The McKenzie women, empowered with a formidable history rooted in the foothills of Appalachia, have passed down their folk-healing wisdom through generations. Rosalee, the last living headstrong daughter in Granny McKenzie’s line, soaked up everything she could about the secrets of the forest before a series of tragedies left her alone, without the protection of the women who came before her.

Olivia McAfee knows what it feels like to start over. Her picture-perfect life—living in Boston, married to a brilliant cardiothoracic surgeon, raising their beautiful son, Asher—was upended when her husband revealed a darker side. She never imagined that she would end up back in her sleepy New Hampshire hometown, living in the house she grew up in and taking over her father’s beekeeping business. Lily Campanello is familiar with do-overs, too. When she and her mom relocate to Adams, New Hampshire, for her final year of high school, they both hope it will be a fresh start.

1857. Three women—once strangers—come together in unpredictable Utah Territory. Hopeful, desperate, and willful, they’ll allow nothing on Earth or in Heaven to stand in their way. Following the call of their newfound Mormon faith, Tamar Loader and her family weather a brutal pilgrimage from England to Utah, where Tamar is united with her destined husband, Thomas Ricks. Clinging to a promise for the future, she abides an unexpected surprise: Thomas is already wedded to one woman—Tabitha, a local healer—and betrothed to still another.

For 14-year-old Wallis Ann Stamper and her family, life in the Appalachian Mountains is simple and satisfying, though not for the tenderhearted. While her older sister, Laci - a mute, musically gifted savant - is constantly watched over and protected, Wallis Ann is as practical and sturdy as her name. When the Tuckasegee River bursts its banks, forcing them to flee in the middle of the night, those qualities save her life. But though her family is eventually reunited, the tragedy opens Wallis Ann's eyes to a world beyond the creek that's borne their name for generations.

In 1969 Dixie Dupree is 11 years old and already an expert liar. Sometimes the lies are for her mama Evie's sake - to explain away a bruise brought on by her quick-as-lightning temper. And sometimes the lies are to spite Evie, who longs to leave her unhappy marriage in Perry County, Alabama, and return to her beloved New Hampshire. But for Dixie and her brother, Alabama is home, a place of pine-scented breezes and hot, languid afternoons.

During the Great Depression, labor camps crop up in remote areas throughout the American South. Destitute workers live under terrible conditions. Trapped in these isolated locations, workers are entirely dependent on the often greedy, abusive camp owners who provide food and housing at grossly inflated prices. But for the most desperate among America's vast unemployed, these camps are often the last and only option.

Generations of Sassers have made moonshine in the Brushy Mountains of Wilkes County, North Carolina. Their history is recorded in a leather-bound journal that belongs to Jessie Sasser's daddy, but Jessie wants no part of it. As far as she's concerned, moonshine caused her mother's death a dozen years ago. Her father refuses to speak about her mama, or about the day she died. But Jessie has a gnawing hunger for the truth - one that compels her to seek comfort in food.

Talk of impending war is a steady drumbeat throughout North Carolina, though Joetta McBride pays it little heed. She and her husband, Ennis, have built a modest but happy life for themselves, raising two sons, fifteen-year-old Henry, and eleven-year-old Robert, on their small subsistence farm. They do not support the Confederacy's position on slavery, but Joetta considers her family to be neutral, believing this is simply not their fight. Her opinion is not favored by many in their community, including Joetta's own father-in-law, Rudean.

Growing up on their hardscrabble farm in rural Kentucky, 15-year-old Albertina "Bertie" Winslow has learned a lot from her mama, Polly. She knows how to lance a boil, make a pie crust, butcher a pig, and tend to every chore that needs doing. What she doesn't know, but is forced to reckon with all too soon, is how to look after children as a mother should. When Polly succumbs to a long illness, Bertie takes on responsibility for her four younger siblings and their dissolute, unreliable daddy.

Deep in the tobacco land of North Carolina, nothing's been the same since the boys shipped off to war and worry took their place. Thirteen-year-old Lucy Brown is precocious and itching for adventure. Then Allie Bert Tucker wanders into town, an outcast with a puzzling past, and Lucy figures the two of them can solve any curious crime they find - just like her hero, Nancy Drew. Their chance comes when a man goes missing, a woman stops speaking, and an eccentric gives the girls a mystery to solve that takes them beyond the ordinary.

On the last day of eighth grade, Maggie begins to dream of finding a way to escape the drudgery and confinement of life in the hollow and establish her independence. Her plan begins to fall in place when she enters high school and discovers she has a natural talent for excelling in shorthand, typing, and other business classes. Meanwhile she spares no effort in helping her family continue to survive despite their poverty, a less than fertile few acres, and a family history of instability.

For years, the town of Silver Bell, Arkansas has quietly mourned the hospital fire that claimed the lives of nine of its residents—the town doctor, a young expectant mother, and seven infants. So, when journalist Finn Hardwick is assigned the story as part of a national thirtieth anniversary memorial service, he arrives at the town ready to interview its residents, thinking they’ll be ready to share and eager to make headlines. He isn’t prepared for the resistance. Or for what appears to be a collective unwillingness to answer his questions.

Although Jessilyn and Gemma’s friendship has weathered the storms of heartache and prejudice, the turbulent summer of 1936 threatens to shatter the ties that bind. After the hit-and-run death of a little girl, Gemma’s explosive revelation could save an innocent man’s life—but not without jeopardizing the livelihood of Jessilyn’s family.

"The dead can't hurt you. Only the living can." Effie Jones, a former slave who escaped to the Union side as a child, knows the truth of her words. Taken in by an army surgeon and his wife during the War, she learned to read and write, to tolerate the sight of blood and broken bodies - and to forget what is too painful to bear. Now a young freedwoman, she has returned south to New Orleans and earns her living as an embalmer, her steady hand and skillful incisions compensating for her white employer's shortcomings.

Eleven-year-old Grace Carter has a talent for hiding things. She's had plenty of practice, burying thoughts and feelings that might anger her strict evangelical pastor father. The Knowing, as Grace calls it, offers glimpses of people's pasts and futures. It enables her to see into the depth of her mother's sadness, and even allows Grace to talk to Isaac, her twin brother who died at birth. To her wise, loving Aunt Pearl, the Knowing is a family gift; to her daddy, it's close to witchcraft.

Sage Winters always knew her sister was a little different even though they were identical twins. They loved the same things and shared a deep understanding, but Rosemary—awake to every emotion, easily moved to joy or tears—seemed to need more protection from the world. Six years after Rosemary's death from pneumonia, Sage, now sixteen, still misses her deeply. Their mother perished in a car crash, and Sage's stepfather, Alan, resents being burdened by a responsibility he never wanted.

On a summer evening in 1931, Lilly Blackwood glimpses circus lights from the grimy window of her attic bedroom. Lilly isn't allowed to explore the meadows around Blackwood Manor. She's never even ventured beyond her narrow room. Momma insists it's for Lilly's own protection, that people would be afraid if they saw her. But on this unforgettable night, Lilly is taken outside for the first time - and sold to the circus sideshow.

Fragrant blossoms herald spring, but the orchard is also a place of secrets and heartache. After the death of her husband Frank, Eliza is left with three young children and mounting debts. When a gentle stranger enters her orchard, she experiences a peculiar sensation of familiarity with the man. But will his unknown past jeopardize all that she has fought for?