• The 2022 ESC/ERS Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension With First Author, Marc Humbert
    Oct 20 2022

    Drs Vallerie McLaughlin and Marc Humbert discuss the 2022 guidelines on pulmonary arterial hypertension by the European Society of Cardiology (ESC) and the European Respiratory Society (ERS).

    Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/968551). The topics and discussions are planned, produced, and reviewed independently of advertiser. This podcast is intended only for US healthcare professionals.

    Resources

    Pulmonary Arterial Hypertension https://emedicine.medscape.com/article/303098-overview

    2022 ESC/ERS Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehac237/6673929

    Pulmonary Arterial Hypertension Risk Stratification https://www.medscape.com/viewarticle/968547

    Pulmonary Function Testing https://emedicine.medscape.com/article/303239-overview

    Pulmonary Angiography Technique https://emedicine.medscape.com/article/2116480-overview

    Show more Show less
    25 mins
  • Diagnosis and Treatment of Chronic Thromboembolic Pulmonary Hypertension
    Sep 22 2022

    Drs Vallerie McLaughlin and Richard Channick discuss the diagnosis and treatment of chronic thromboembolic pulmonary hypertension.

    Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/968550). The topics and discussions are planned, produced, and reviewed independently of advertiser. This podcast is intended only for US healthcare professionals.

    Resources

    Pulmonary Hypertension https://www.medscape.com/answers/303098-93380/what-is-pulmonary-hypertension

    Chronic Thromboembolic Pulmonary Hypertension (CTEPH) https://emedicine.medscape.com/article/2500057-overview

    Pulmonary Embolism https://emedicine.medscape.com/article/300901-overview

    Determinants of Diagnostic Delay in Chronic Thromboembolic Pulmonary Hypertension: Results From the European CTEPH Registry https://erj.ersjournals.com/content/52/6/1801687

    Pulmonary Embolism Response Teams: Purpose, Evidence for Efficacy, and Future Research Directions https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611377

    V/Q Scan https://www.medscape.com/answers/300901-8522/how-is-vq-scanning-used-for-the-diagnosis-of-pulmonary-embolism-pe

    Multidetector Computed Tomography for Acute Pulmonary Embolism https://www.nejm.org/doi/10.1056/NEJMoa052367

    Pulmonary Thromboendarterectomy https://www.medscape.org/viewarticle/556058_4

    Dynamic Risk Stratification of Patient Long-term Outcome After Pulmonary Endarterectomy: Results From the United Kingdom National Cohort https://pubmed.ncbi.nlm.nih.gov/27052413/

    Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension https://err.ersjournals.com/content/26/143/160119

    Balloon Pulmonary Angioplasty as a Treatment in Chronic Thromboembolic Pulmonary Hypertension: Past, Present, and Future https://pubmed.ncbi.nlm.nih.gov/32056029/

    Pulmonary Arterial Hypertension Clinical Presentation https://emedicine.medscape.com/article/303098-clinical

    Riociguat https://reference.medscape.com/drug/adempas-riociguat-999863

    Long-term Clinical Value and Outcome of Riociguat in Chronic Thromboembolic Pulmonary Hypertension https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396196/

    Riociguat Prescribing Information https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/204819s006lbl.pdf

    Show more Show less
    23 mins
  • Identifying and Navigating Challenging Clinical Scenarios in Pulmonary Arterial Hypertension
    Aug 25 2022

    Drs Vallerie McLaughlin and Oksana Shlobin discuss methods of identifying and navigating challenging clinical scenarios in pulmonary arterial hypertension.

    Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/968548). The topics and discussions are planned, produced, and reviewed independently of advertiser. This podcast is intended only for US healthcare professionals.

    Resources

    What Is Pulmonary Hypertension? https://www.medscape.com/answers/303098-93380/what-is-pulmonary-hypertension

    What Are the WHO Clinical Classifications of Pulmonary Hypertension? https://www.medscape.com/answers/303098-93381/what-are-the-who-clinical-classifications-of-pulmonary-hypertension

    Interstitial Lung Disease: Pathophysiology and Genetic Predisposition https://www.medscape.com/viewarticle/408750

    What Is the Role of Pulmonary Function Testing in the Evaluation of Restrictive Lung Disease? https://www.medscape.com/answers/301760-187987/what-is-the-role-of-pulmonary-function-testing-in-the-evaluation-of-restrictive-lung-disease

    What Is the Six-Minute Walk Test (6mwt) in Pulmonary Function Testing? https://www.medscape.com/answers/303239-77869/what-is-the-six-minute-walk-test-6mwt-in-pulmonary-function-testing

    Respiratory Failure-V/Q Mismatch https://emedicine.medscape.com/article/167981-overview#a4

    Efficacy and Safety of Riociguat in Patients With Symptomatic Pulmonary Hypertension (PH) Associated With Idiopathic Interstitial Pneumonias (IIP) (RISE-IIP) https://clinicaltrials.gov/ct2/show/NCT02138825

    Pulmonary Veno-Occlusive Disease https://emedicine.medscape.com/article/1464015-overview

    Sodium-Glucose Cotransporter 2 Inhibitors: An Overview https://www.medscape.com/viewarticle/892957_9

    Treatment Approach to Connective Tissue Disease-Associated Interstitial Lung Disease https://www.sciencedirect.com/science/article/abs/pii/S1471489222000728

    Show more Show less
    21 mins
  • Pulmonary Arterial Hypertension Risk Stratification
    Jul 21 2022

    Drs Vallerie McLaughlin and Ioana Preston discuss how equations and prediction models guide risk stratification of patients diagnosed with pulmonary arterial hypertension.

    Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/968547). The topics and discussions are planned, produced, and reviewed independently of advertiser. This podcast is intended only for US healthcare professionals.

    Resources

    Pulmonary Arterial Hypertension https://emedicine.medscape.com/article/303098-overview

    REVEAL Registry: Registry to Evaluate Early and Long-term PAH Disease Management https://clinicaltrials.gov/ct2/show/NCT00370214

    Predicting Survival in Pulmonary Arterial Hypertension: Insights From the Registry to Evaluate Early and Long-term Pulmonary Arterial Hypertension Disease Management (REVEAL) https://doi.org/10.1161/CIRCULATIONAHA.109.898122

    Predicting Survival in Patients With Pulmonary Arterial Hypertension: The REVEAL Risk Score Calculator 2.0 and Comparison With ESC/ERS-Based Risk Assessment Strategies https://doi.org/10.1016/j.chest.2019.02.004

    Development and Validation of an Abridged Version of the REVEAL 2.0 Risk Score Calculator, REVEAL Lite 2, for Use in Patients With Pulmonary Arterial Hypertension https://doi.org/10.1016/j.chest.2020.08.2069

    REVEAL Lite 2 Risk Calculator https://pahriskcalculatorlt.com/

    Brain-Type Natriuretic Peptide (BNP) https://emedicine.medscape.com/article/2087425-overview

    2015 ESC/ERS Guidelines for the diagnosis and Treatment of Pulmonary Hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT) https://doi.org/10.1093/eurheartj/ehv317

    Risk Assessment in Pulmonary Arterial Hypertension https://erj.ersjournals.com/content/51/3/1702606

    A Comprehensive Risk Stratification at Early Follow-up Determines Prognosis in Pulmonary Arterial Hypertension https://doi.org/10.1093/eurheartj/ehx257

    Risk Assessment, Prognosis and Guideline Implementation in Pulmonary Arterial Hypertension https://doi.org/10.1183/13993003.00889-2017

    Risk Assessment in Pulmonary Arterial Hypertension https://doi.org/10.1183/13993003.02606-2017

    Regular Risk Assessment in Pulmonary Arterial Hypertension - A Whistleblower for Hidden Disease Progression https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888324

    A Pragmatic Approach to Risk Assessment in Pulmonary Arterial Hypertension Using the 2015 European Society of Cardiology/European Respiratory Society Guidelines https://openheart.bmj.com/content/8/2/e001725.long

    Risk Assessment in Precapillary Pulmonary Hypertension: A Comparative Analysis https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-021-01624-z

    Diagnostic and Predictive Value of Right Heart Catheterization-Derived Measurements in Pulmonary Hypertension https://doi.org/10.36740/WLek202103130

    Scleroderma https://emedicine.medscape.com/article/331864-overview

    COMPERA 2.0: A Refined 4-Strata Risk Assessment Model for Pulmonary Arterial Hypertension https://doi.org/10.1183/13993003.02311-2021

    Show more Show less
    24 mins
  • Diagnosis of PAH: What Are the Causes and Why Does It Take So Long?
    Jun 23 2022

    Drs Vallerie McLaughlin and Paul Forfia discuss the diagnosis of PAH. What are the causes and why does it take so long?

    Relevant disclosures can be found with the episode show notes on Medscape.com (https://www.medscape.com/viewarticle/968546). The topics and discussions are planned, produced, and reviewed independently of advertiser. This podcast is intended only for US healthcare professionals.

    Resources

    Pulmonary Arterial Hypertension https://emedicine.medscape.com/article/303098-overview

    The 'Great Wait' for Diagnosis in Pulmonary Arterial Hypertension https://onlinelibrary.wiley.com/doi/full/10.1111/resp.13814

    Systemic Consequences of Pulmonary Hypertension and Right-Sided Heart Failure https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.116.022362

    Management of Coronary Artery Disease and Chronic Stable Angina https://www.medscape.com/viewarticle/881468

    What Is Myocardial Ischemia? https://www.medscape.com/answers/352401-192899/what-is-myocardial-ischemia

    Chronic Obstructive Pulmonary Disease (COPD) https://emedicine.medscape.com/article/297664-overview

    Group 4 Pulmonary Hypertension https://emedicine.medscape.com/article/2500057-overview

    Pulmonary Arterial Hypertension in Connective Tissue Disorders: Pathophysiology and Treatment https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405825

    Scleroderma https://emedicine.medscape.com/article/331864-overview

    Pulmonary Hypertension Phenotypes in Patients With Systemic Sclerosis https://err.ersjournals.com/content/30/161/210053.long

    Mixed Connective-Tissue Disease (MCTD) https://emedicine.medscape.com/article/335815-overview

    Systemic Lupus Erythematosus (SLE) https://emedicine.medscape.com/article/332244-overview

    Sjogren Syndrome https://emedicine.medscape.com/article/332125-overview

    Pulmonary Arterial Hypertension in Patients Infected With the Human Immunodeficiency Virus https://www.sciencedirect.com/science/article/abs/pii/S0733865121000679?via%3Dihub

    Portal Hypertension https://emedicine.medscape.com/article/182098-overview

    Liver Abnormalities in Pulmonary Arterial Hypertension https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544777/

    Pulmonary Hypertension in Adults With Congenital Heart Disease https://www.sciencedirect.com/science/article/abs/pii/S0733865121000692?via%3Dihub

    Atrial Septal Defect https://emedicine.medscape.com/article/162914-overview

    Anorexigens and Pulmonary Hypertension in the United States https://linkinghub.elsevier.com/retrieve/pii/S0012-3692(15)32749-5

    Methamphetamine and the Risk of Pulmonary Arterial Hypertension https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880795/

    Echocardiography in Pulmonary Arterial Hypertension: Comprehensive Evaluation and Technical Considerations https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348437/pdf/jcm-10-03229.pdf

    Echocardiography https://emedicine.medscape.com/article/1820912-overview

    Echocardiography Can Identify Patients With Increased Pulmonary Vascular Resistance by Assessing Pressure Reflection in the Pulmonary Circulation https://www.ahajournals.org/doi/10.1161/circimaging.109.913467

    Pulmonary Resistance https://reference.medscape.com/calculator/189/pulmonary-resistance

    Right Heart Adaptation to Pulmonary Arterial Hypertension: Physiology and Pathobiology https://www.sciencedirect.com/science/article/pii/S0735109713058701?via%3Dihub

    RV Systolic Pressure (TR Jet) https://reference.medscape.com/calculator/200/rv-systolic-pressure-tr-jet

    Modified Bernoulli Formula https://reference.medscape.com/calculator/150/modified-bernoulli-equation

    Limitations and Strengths of Doppler/Echo Pulmonary Artery Systolic Pressure-Right Heart Catheterization Correlations: A Systematic Literature Review https://onlinelibrary.wiley.com/doi/10.1111/echo.12594

    Show more Show less
    23 mins
  • Classifications and Causes of Pulmonary Hypertension
    Jun 23 2022

    Drs Vallerie McLaughlin and Raymond Benza discuss the classifications and causes of pulmonary hypertension.

    Relevant disclosures can be found with the episode show notes on Medscape.com (https://www.medscape.com/viewarticle/968545). The topics and discussions are planned, produced, and reviewed independently of advertiser. This podcast is intended only for US healthcare professionals.

    Resources

    Pulmonary Arterial Hypertension https://emedicine.medscape.com/article/303098-overview#a4

    The Definition of Pulmonary Hypertension: History, Practical Implications and Current Controversies https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753640/pdf/EDU-0076-2021.pdf

    Pulmonary Hypertension https://phassociation.org/types-pulmonary-hypertension-groups/

    Group 2 Pulmonary Hypertension https://emedicine.medscape.com/article/2500055-overview

    Group 3 Pulmonary Hypertension https://emedicine.medscape.com/article/2500056-overview

    Group 4 Pulmonary Hypertension https://emedicine.medscape.com/article/2500057-overview

    Predicting Survival in Pulmonary Arterial Hypertension: Insights From the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL) https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.109.898122

    Evidence-Based Detection of Pulmonary Arterial Hypertension in Systemic Sclerosis: The DETECT Study https://ard.bmj.com/content/73/7/1340

    Show more Show less
    23 mins