Genetic Disease

Trauma is a fact of life. Veterans and their families deal with the painful aftermath of combat; one in five Americans has been molested; one in four grew up with alcoholics; one in three couples have engaged in physical violence. Dr. Bessel van der Kolk, one of the world’s foremost experts on trauma, has spent more than three decades working with survivors. In The Body Keeps the Score, he uses recent scientific advances to show how trauma literally reshapes both body and brain, compromising sufferers’ capacities for pleasure, engagement, self-control, and trust.

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the 20-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics.

In Beat the Heart Attack Gene, world-renowned cardiovascular specialists Bradley Bale, MD, and Amy Doneen, ARNP, present a new model for understanding and preventing heart disease. They explain the three different genetic types of cholesterol profiles and tailor treatments for each type, using their cutting-edge Bale/Doneen Method, a simple, comprehensive prevention plan that detects cardiovascular disease (CVD) at early stages.

From an acclaimed Harvard professor and one of Time’s most influential people, this paradigm-shifting audiobook shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls listeners to consider a future where aging can be treated.

Contrary to conventional wisdom, chronic disease is not genetically predetermined but results from a mismatch between our genes and environment and lifestyle. What we call a "disease" is the outcome of an imbalance in one or more of the seven core physiological processes. Leveraging a lifetime on the cutting edge of research and practice, Dr. Jeffrey S. Bland lays out a road map for good health by helping us understand these processes and the root causes of chronic illness.

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML).

You are just 10% human. For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony. Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.

Every 69 seconds, someone is diagnosed with Alzheimer's disease. Of the top 10 killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can. The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer's, an inherited genetic mutation that causes the disease in 100 percent of cases, and has a 50 percent chance of being passed onto the next generation.

A leading expert in epigenetics - how genes switch on and off - provides a revolutionary, holistic, and personalized approach to better health by improving how your genes behave to prevent and reverse common ailments, chronic illnesses, and life-threatening diseases, including cardiovascular disease, autoimmune disorders, anxiety, depression, digestive issues, obesity, cancer, diabetes, and more.

A leading brain scientist's look at the neurobiology of pleasure-and how pleasures can become addictions. Whether eating, taking drugs, engaging in sex, or doing good deeds, the pursuit of pleasure is a central drive of the human animal. In The Compass of Pleasure Johns Hopkins neuroscientist David J. Linden explains how pleasure affects us at the most fundamental level: in our brain.

In The Genetic Lottery, Harden introduces listeners to the latest genetic science, dismantling dangerous ideas about racial superiority and challenging us to grapple with what equality really means in a world where people are born different. Weaving together personal stories with scientific evidence, Harden shows why our refusal to recognize the power of DNA perpetuates the myth of meritocracy, and argues that we must acknowledge the role of genetic luck if we are ever to create a fair society.

Do you live with a chronic, debilitating, yet invisible condition? You may feel isolated, out of step, judged, lonely, or misunderstood - and that's on top of dealing with your actual illness. Take heart. You are not alone, although sometimes it can feel that way. Written by a blogger who suffers from an invisible chronic illness, Surviving and Thriving with an Invisible Chronic Illness offers peer-to-peer support to help you stay sane, be your own advocate, and get back to living your life. This compelling guide is written for anyone suffering with an illness no one can see.

In Mercies in Disguise, acclaimed New York Times reporter and best-selling author Gina Kolata tells the story of the Baxleys, an upstanding family in small-town South Carolina. Many of them were doctors, but still, they are struck down by an inscrutable illness. Finally they discover the cause of the disease after a remarkable sequence of providential events. Meanwhile science, progressing for 50 years along a parallel track, handed the Baxleys a question - not a cure but a blood test that would reveal who had the gene for the disease.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

Oncologist and cancer gene hunter Theo Ross delivers the first authoritative go-to for people facing a genetic predisposition for cancer. This book empowers listeners to face their genetic heritage without fear and to make decisions that will keep them and their families healthy.

In this landmark book of popular science, Daniel E. Lieberman - chair of the department of human evolutionary biology at Harvard University and a leader in the field - gives us a lucid and engaging account of how the human body evolved over millions of years, even as it shows how the increasing disparity between the jumble of adaptations in our Stone Age bodies and advancements in the modern world is occasioning this paradox: greater longevity but increased chronic disease.

“Thought-provoking and exhilarating story - highly recommend!” “Finished this book in 24 hours, just didn’t want to put it down!” “Captivating! I stayed up way too long finishing it... Highly recommend!” In the heart of Antarctica, rookie researcher Sonny Evans celebrates drilling the world’s oldest ice core. The frozen window in time is the first glimpse of life millions of years ago. Soon after returning home, a deadly contagion sweeps across the globe, claiming victims at an alarming rate. As the body count grows, Sonny can't shake the feeling that his Antarctic ...

A Sick Life chronicles Tionne's journey from a childhood spent in and out of the hospital, told she wouldn't live to see 30 or have children, to becoming the superstar musician who is still living out her life's dream of performing. For the first time, Tionne will tell her full life story - the diagnosis, the tumultuous rise to fame, the life in the spotlight, and the hard-fought advocacy work.

In this book, biotechnology entrepreneur and CEO of The DNA Company Kashif Khan offers an action plan to help you live your best life. It starts by understanding your genetic makeup.

For patients with chronic pain and those who love them, an exploration of the causes of and treatments available for those with hypermobility.