Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

Perception marries academic rigor with mainstream accessibility. The research presented and the personalities profiled will show what it means to not only have, but be, your unique human body. The positive ramifications of viewing ourselves from this embodied perspective include greater athletic, academic, and professional achievement, more nourishing relationships, and greater personal well-being. The better we can understand what our bodies are - what they excel at, what they need, what they must avoid - the better we can live our lives.

In 1939, Richard Feynman, a brilliant graduate of MIT, arrived in John Wheeler's Princeton office to report for duty as his teaching assistant. A lifelong friendship and enormously productive collaboration was born, despite sharp differences in personality. The soft-spoken Wheeler, though conservative in appearance, was a raging nonconformist full of wild ideas about the universe. The boisterous Feynman was a cautious physicist who believed only what could be tested. Yet they were complementary spirits.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight-how the same simple chemistry gives rise to life and causes our demise.

James D. Watson, the Nobel laureate whose pioneering work helped unlock the mystery of DNA's structure, charts the greatest scientific journey of our time, from the discovery of the double helix to today's controversies to what the future may hold. Updated to include new findings in gene editing, epigenetics, and agricultural chemistry as well as two entirely new chapters on personal genomics and cancer research. This is the most comprehensive and authoritative exploration of DNA's impact on our society and our world.

You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door. So what, exactly, is your immune system? In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defenses.

One of our great contemporary scientists reveals the 10 profound insights that illuminate what everyone should know about the physical world.

Earth evolves. From first atom to molecule, mineral to magma, granite crust to single cell to verdant living landscape, ours is a planet constantly in flux. In this radical new approach to Earth’s biography, senior Carnegie Institution researcher and national best-selling author Robert M. Hazen reveals how the co-evolution of the geosphere and biosphere - of rocks and living matter - has shaped our planet into the only one of its kind in the Solar System, if not the entire cosmos.

Engrossing and captivating, Editing Humanity takes listeners inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces listeners to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.

A breakout best seller in Italy, now available for American listeners for the first time, Genesis: The Story of How Everything Began is a short, humanistic tour of the origins of the universe, earth, and life - drawing on the latest discoveries in physics to explain the seven most significant moments in the creation of the cosmos.

Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.

Oxygen takes the listener on an enthralling journey, as gripping as a thriller, as it unravels the unexpected ways in which oxygen spurred the evolution of life and death.

From Jack the Ripper to the modern-day drug cartels, discover the most notorious crimes and criminals in history. With a foreword written and narrated by best-selling crime author Peter James, The Crime Book explores over 100 crimes and examines the science, psychology and sociology of criminal behavior. Hear the gory details of each crime and how they were solved, with renowned quotes and detailed criminal profiles letting you delve into the criminal mind.