The Genome Odyssey
Medical Mysteries and the Incredible Quest to Solve Them
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Narrated by:
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Dr. Euan Angus Ashley
About this listen
This program is read by the author.
In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.
Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere 40 cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000.
For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human.
In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces listeners to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures.
He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome.
These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.
A Macmillan Audio production from Celadon Books
PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.
©2021 Dr. Euan Angus Ashley (P)2021 Macmillan AudioListeners also enjoyed...
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- Unabridged
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The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".
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Incredible
- By S.R.E. on 03-02-16
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A Shot to Save the World
- The Inside Story of the Life-or-Death Race for a COVID-19 Vaccine
- By: Gregory Zuckerman
- Narrated by: Jack Armstrong
- Length: 12 hrs and 6 mins
- Unabridged
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Few were ready when a mysterious respiratory illness emerged in Wuhan, China, in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization.
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Wow! Do not miss this one.
- By Jacob on 11-18-21
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Plague of Corruption
- Restoring Faith in the Promise of Science
- By: Dr. Judy Mikovits, Kent Heckenlively, Robert F. Kennedy Jr.
- Narrated by: Mariel Hemingway
- Length: 10 hrs and 10 mins
- Unabridged
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Dr. Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys' club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried.
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If only most of the public knew these facts
- By David Getoff, CCN on 06-18-20
By: Dr. Judy Mikovits, and others
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How Doctors Think
- By: Jerome Groopman M.D.
- Narrated by: Michael Prichard
- Length: 10 hrs and 27 mins
- Unabridged
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On average, a physician will interrupt a patient describing her symptoms within 12 seconds. In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong: with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make.
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Disappointing
- By Audiophile on 05-13-07
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The Heart Healers
- The Misfits, Mavericks, and Rebels Who Created the Greatest Medical Breakthrough of Our Lives
- By: James Forrester MD
- Narrated by: Jonathan Yen
- Length: 15 hrs and 45 mins
- Unabridged
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At one time heart disease was a death sentence. By the middle of the 20th century, it was killing millions, and, as with the Black Death centuries before, physicians stood helpless. Visionaries, though, had begun to make strides earlier. On September 7, 1895, Ludwig Rehn successfully sutured the heart of a living man with a knife wound to the chest for the first time.
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Great review of the landmark achievements in Cardiology.
- By Trauma NP on 12-14-15
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- By: Daniel M. Davis
- Narrated by: Christopher Grove
- Length: 7 hrs and 48 mins
- Unabridged
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Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
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The Cancer Chronicles
- Unlocking Medicine's Deepest Mystery
- By: George Johnson
- Narrated by: Arthur Morey
- Length: 8 hrs and 19 mins
- Unabridged
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When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.
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A quick read - hard to put down
- By Digital Dilema on 09-06-13
By: George Johnson
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Happy Accidents
- Serendipity in Major Medical Breakthroughs in the Twentieth Century
- By: Morton A. Meyers
- Narrated by: Richard Waterhouse
- Length: 12 hrs and 37 mins
- Unabridged
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Happy Accidents is a fascinating, entertaining, and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the 20th century. What do penicillin, chemotherapy drugs, X-rays, Valium, the Pap smear, and Viagra have in common? They were each discovered accidentally, stumbled upon in the search for something else. In discussing medical breakthroughs, Dr. Morton Meyers makes a cogent, highly engaging argument for a more creative, rather than purely linear, approach to science. And it may just save our lives!
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Don't waste your money!
- By Amazon Customer on 03-20-16
By: Morton A. Meyers
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Missing Microbes
- How the Overuse of Antibiotics Is Fueling Our Modern Plagues
- By: Martin J. Blaser
- Narrated by: Patrick Lawlor
- Length: 8 hrs and 43 mins
- Unabridged
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In Missing Microbes, Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now this invisible eden is being irrevocably damaged by some of our most revered medical advances-antibiotics-threatening the extinction of our irreplaceable microbes with terrible health consequences.
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Very enlightening and information well supported
- By James on 05-03-15
By: Martin J. Blaser
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A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- By: Jennifer A. Doudna, Samuel H. Sternberg
- Narrated by: Erin Bennett
- Length: 9 hrs and 22 mins
- Unabridged
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Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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In to the abyss we ascend, a scary future
- By Philomath on 06-17-17
By: Jennifer A. Doudna, and others
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Chronic
- The Hidden Cause of the Autoimmune Pandemic and How to Get Healthy Again
- By: Steven Phillips MD, Dana Parish, Kristin Loberg
- Narrated by: Teri Schnaubelt, Thomas Allen
- Length: 10 hrs and 42 mins
- Unabridged
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In this timely book, Steven Phillips, MD, and his former patient, Sony singer-songwriter Dana Parish, reveal striking evidence that a broad range of common infections, from COVID-19 to Lyme and many others, cause a variety of autoimmune, psychiatric, and chronic conditions. Chronic explores the science behind what makes them difficult to diagnose and treat, debunks widely held beliefs by doctors and patients alike, and provides solutions that empower sufferers to reclaim their lives.
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A must read book
- By Amazon Customer on 03-01-21
By: Steven Phillips MD, and others
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- By: Thomas Hager
- Narrated by: Angelo Di Loreto
- Length: 8 hrs and 39 mins
- Unabridged
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Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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Engrossing to physicians & lay persons alike
- By C. White on 03-08-19
By: Thomas Hager
What listeners say about The Genome Odyssey
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Austin Bow
- 03-17-21
Great Narration and Content!
A concise and easy to follow exploration into the complex topic of genomics. The ever blossoming field of multi-omics can be daunting but works like this offer all the more encouragement for approaching such topics to further research that can have a direct and meaningful impact on lives.
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2 people found this helpful
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- Anonymous User
- 03-29-21
Fascinating
As someone interested in healthcare and technology but without a lot of formal biology training, this book offered a blend of interesting narrative and review of the science or applying genomics in medicine. Would highly recommend to fans of Gawande and Topol.
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3 people found this helpful
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- Amazon Customer
- 04-05-21
if you are human, read ir
I am still processing but this is a book that has changed me and my place in this world in ways I have yet to understand.
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3 people found this helpful
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- Placeholder
- 10-06-23
Outstanding story of the genome revolution
An incredible account of the genome revolution from the front lines! Uniquely, narrated by the author, Dr. Ashley who has an incredible story to tell of how the foundations for the revolution were laid at Stanford and how that work has translated to remarkable stories of how patients were diagnosed and treated in the clinic. One of the best books I've read in recent times, highly recommended for anyone interested in genomics and its application in practice.
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- Ori
- 03-17-21
Easy to understand and to follow
Good, not excellent.
Undoubtedly, shade the light on the future potential of genetics in genetics genetics treatment.
Written for the general audience. For new comers to the genetics field it provides good introduction for the current use and future potential of genomics in medicine and health care.
Tnx for the reference.
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3 people found this helpful
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- kenissur
- 07-11-22
Interesting at times but repetitive, badly written
Some of the stories are very interesting, but the author did a bad job of making a book or story out of them. The characters, doctors, scientists and patients, are all flawlessly positive and outstanding in several ways, making this book sound like a collection of high school level assays.
Also, there is an unmistakable thread of arrogance and pride of the author himself, with sparkles of flase modesty, that make this into an unpleasant read/listen.
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3 people found this helpful