Madame Restell is a sharp, witty Gilded Age medical history which introduces us to an iconic, yet tragically overlooked, feminist heroine: a glamorous women’s healthcare provider in Manhattan, known to the world as Madame Restell. A celebrity in her day with a flair for high fashion and public, petty beefs, Restell was a self-made woman and single mother who used her wit, her compassion, and her knowledge of family medicine to become one of the most in-demand medical workers in New York.

Spanning eras and cultures from ancient Rome to medieval England to 1950s Hollywood, Jennifer Wright's It Ended Badly guides you through the worst of the worst in historically bad breakups. In the throes of heartbreak, Emperor Nero had just about everyone he ever loved - from his old tutor to most of his friends - put to death. Oscar Wilde's lover, whom he went to jail for, abandoned him when faced with being cut off financially from his wealthy family.

The story of poison is the story of power. For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns, and antidotes tested on condemned prisoners. Servants licked the royal family's spoons, tried on their underpants, and tested their chamber pots. Ironically, royals terrified of poison were unknowingly poisoning themselves daily with their cosmetics, medications, and filthy living conditions.

Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

In this fascinating and thought-provoking book, author Nick Lane brings together the latest research findings in the exciting field of mitochondria research to reveal how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death.

The Viking Age - from 750 to 1050 saw an unprecedented expansion of the Scandinavian peoples into the wider world. As traders and raiders, explorers and colonists, they ranged from eastern North America to the Asian steppe. But for centuries, the Vikings have been seen through the eyes of others, distorted to suit the tastes of medieval clerics and Elizabethan playwrights, Victorian imperialists, Nazis, and more. None of these appropriations capture the real Vikings, or the richness and sophistication of their culture.

From colorful 30,000-year-old threads found on the floor of a Georgian cave to the Indian calicoes that sparked the Industrial Revolution, The Golden Thread weaves an illuminating story of human ingenuity. Design journalist Kassia St. Clair guides us through the technological advancements and cultural customs that would redefine human civilization - from the fabric that allowed mankind to achieve extraordinary things (traverse the oceans and shatter athletic records) and survive in unlikely places (outer space and the South Pole).

In Will My Cat Eat My Eyeballs?, Doughty blends her mortician’s knowledge of the body and the intriguing history behind common misconceptions about corpses to offer factual, hilarious, and candid answers to 35 distinctive questions posed by her youngest fans. In her inimitable voice, Doughty details lore and science of what happens to, and inside, our bodies after we die. Why do corpses groan? What causes bodies to turn colors during decomposition? And why do hair and nails appear longer after death?

Devil Take the Hindmost is a lively, original, and challenging history of stock market speculation from the 17th century to the present day. Edward Chancellor traces the origins of the speculative spirit back to ancient Rome and chronicles its revival in the modern world.

In this illuminating audiobook, Tyson and coauthor James Trefil, a renowned physicist and science popularizer, take on the big questions that humanity has been posing for millennia - How did life begin? What is our place in the universe? Are we alone? - and provide answers based on the most current data, observations, and theories.

Informed by cutting-edge scientific research and sparkling with memorable characters - from the modern druids who worship at Stonehenge each solstice to the Amish farmers who may have the right idea about healthy sleep patterns - Linda Geddes’s Chasing the Sun analyzes all aspects of our relationship to the sun. The fascinating stories, innovative science, and unique perspectives in this book make it clear that the ancients were right to put the sun at the center of our world and that it is crucial that we remember this bond as we shape our lives today.

In this award-winning Audible Studios production, Trevor Noah tells his wild coming-of-age tale during the twilight of apartheid in South Africa. It’s a story that begins with his mother throwing him from a moving van to save him from a potentially fatal dispute with gangsters, then follows the budding comedian’s path to self-discovery through episodes both poignant and comical.

In the winter of 1918, at the height of World War I, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 weeks than AIDS has killed in 24 years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision between modern science and epidemic disease.

For two thousand years, cadavers have been involved in science's boldest strides and weirdest undertakings. They've tested France's first guillotines, ridden the NASA Space Shuttle, been crucified in a Parisian laboratory to test the authenticity of the Shroud of Turin, and helped solve the mystery of TWA Flight 800. For every new surgical procedure, from heart transplants to gender reassignment surgery, cadavers have been there alongside surgeons, making history in their quiet way.

An inside account of the fight to contain the world's deadliest diseases - and the panic and corruption that make them worse. The Next Pandemic is a firsthand account of disasters like anthrax, bird flu, and others - and how we could do more to prevent their return. It is both a gripping story of our brushes with fate and an urgent lesson on how we can keep ourselves safe from the inevitable next pandemic.

In 1918, the world was still in the throes of the Great War, the deadliest conflict in human history at that point, but while World War I would be a catastrophic war surpassed only by World War II, an unprecedented influenza outbreak that same year inflicted casualties that would make both wars pale in comparison.

For 200 years, a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. What these strange conditions share is their cause: prions.

In this gripping narrative history, Laura Spinney traces the overlooked pandemic to reveal how the virus travelled across the globe, exposing mankind's vulnerability and putting our ingenuity to the test. As socially significant as both world wars, the Spanish flu dramatically disrupted - and often permanently altered - global politics, race relations, and family structures while spurring innovation in medicine, religion, and the arts.

It can come in waves - like tidal waves. It changes societies. It disrupts life. It ends lives. As far back as 3000 B.C.E. (the Bronze Age), plagues have stricken mankind. COVID-19 is just the latest example, but history shows that life continues. It shows that knowledge and social cooperation can save lives. Viruses are neither alive nor dead and are the closest thing we have to zombies. Their only known function is to replicate themselves, which can have devastating consequences on their hosts.

In the winter of 1918, at the height of World War I, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 weeks than AIDS has killed in 24 years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision between modern science and epidemic disease.

A fascinating account of the world’s most famous disease - polio - told as you have never heard it before. Epidemics of paralysis began to rage in the early 1900s, seemingly out of nowhere. Doctors, parents, and health officials were at a loss to explain why this formerly unheard-of disease began paralyzing so many children. Why did this disease start to become such a horrible problem during the late 1800s? Why did it affect children more often than adults? Why was it originally called teething paralysis by mothers and their doctors?

The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic medication. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.

In 1918, a world war raged, and a lethal strain of influenza circled the globe. In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it spread worldwide, leaving millions dead or locked in institutions. Then, in 1927, it disappeared as suddenly as it had arrived. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and asylums as they try to solve this epidemic and treat its victims - who learned the worst fate was not dying of it, but surviving it.

David Oshinsky, whose last book, Polio: An American Story, was awarded a Pulitzer Prize, chronicles the history of America's oldest hospital and in so doing also charts the rise of New York to the nation's preeminent city, the path of American medicine from butchery and quackery to a professional and scientific endeavor, and the growth of a civic institution.

When three-month-old Lia Lee arrived at the county hospital emergency room in Merced, California, a chain of events was set in motion from which neither she nor her parents nor her doctors would ever recover. Lia's parents, Foua and Nao Kao, were part of a large Hmong community in Merced, refugees from the CIA-run "Quiet War" in Laos.

What won't we try in our quest for perfect health, beauty, and the fountain of youth? Well, just imagine a time when doctors prescribed morphine for crying infants. When liquefied gold was touted as immortality in a glass. And when strychnine - yes, that strychnine, the one used in rat poison - was dosed like Viagra. Looking back with fascination, horror, and not a little dash of dark, knowing humor, Quackery recounts the lively, at times unbelievable, history of medical misfires and malpractices.

This comprehensive and gripping narrative, which received the 2006 Pulitzer Prize for history, covers all the challenges, characters, and controversies in America's relentless struggle against polio. Funded by philanthropy and grassroots contributions, Salk's killed-virus vaccine (1954) and Sabin's live-virus vaccine (1961) began to eradicate this dreaded disease.

Feeling feverish, tired, or achy? Listening to Gina Kolata's engrossing account of the 1918 Influenza epidemic is sure to give you the chills. A gripping work of science writing, Flu addresses the prospects for a great epidemic recurring, and considers what can be done to prevent it.

In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.

Few diseases are more gruesome than typhus. Transmitted by body lice, it afflicts the dispossessed - refugees, soldiers, and ghettoized peoples - causing hallucinations, terrible headaches, boiling fever, and often death. The disease plagued the German army on the Eastern Front and left the Reich desperate for a vaccine. For this they turned to the brilliant and eccentric Polish zoologist Rudolf Weigl.

Spanning eras and cultures from ancient Rome to medieval England to 1950s Hollywood, Jennifer Wright's It Ended Badly guides you through the worst of the worst in historically bad breakups. In the throes of heartbreak, Emperor Nero had just about everyone he ever loved - from his old tutor to most of his friends - put to death. Oscar Wilde's lover, whom he went to jail for, abandoned him when faced with being cut off financially from his wealthy family.

We live in a world of seeds. From our morning toast to the cotton in our clothes, they are quite literally the stuff and staff of life, supporting diets, economies, and civilizations around the globe. Just as the search for nutmeg and the humble peppercorn drove the Age of Discovery, so did coffee beans help fuel the Enlightenment and cottonseed help spark the Industrial Revolution. And from the fall of Rome to the Arab Spring, the fate of nations continues to hinge on the seeds of a Middle Eastern grass known as wheat.

The story of poison is the story of power. For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns, and antidotes tested on condemned prisoners. Servants licked the royal family's spoons, tried on their underpants, and tested their chamber pots. Ironically, royals terrified of poison were unknowingly poisoning themselves daily with their cosmetics, medications, and filthy living conditions.

Lucie Blackman - tall, blond, 21 years old - stepped out into the vastness of Tokyo in the summer of 2000 and disappeared. The following winter, her dismembered remains were found buried in a seaside cave. The seven months in between had seen a massive search for the missing girl involving Japanese policemen, British private detectives, and Lucie’s desperate but bitterly divided parents. Had Lucie been abducted by a religious cult or snatched by human traffickers? Who was the mysterious man she had gone to meet? And what did her work as a hostess in the notorious Roppongi district of Tokyo really involve?

Filled to the brim with far-out facts, this wickedly informative narrative from the author of National Geographic's popular Gory Details blog takes us on a fascinating journey through an astonishing new reality. Blending humor and journalism in the tradition of Mary Roach, acclaimed science reporter Erika Engelhaupt investigates the gross, strange, and morbid absurdities of our bodies and our universe.

From the masters of storytelling-meets-science, Patient Zero tells the long and fascinating history of disease outbreaks—how they start, how they spread, the science that lets us understand them, and how we race to destroy them before they destroy us. Written in the authors’ lively style, chapters include gripping medical stories about a particular disease or virus—smallpox, Bubonic plague, polio, HIV—that combine “Patient Zero” narratives, or the human stories behind outbreaks, with historical examinations of missteps, milestones, scientific theories, and more.

Drawing on his decades of field research and up-to-the-minute understanding of the latest science, renowned geologist Andrew H. Knoll delivers a rigorous yet accessible biography of Earth, charting our home planet's epic 4.6 billion-year story. Placing 21st-century climate change in deep context, A Brief History of Earth is an indispensable look at where we’ve been and where we’re going.

In February 1959, a group of nine experienced hikers in the Russian Ural Mountains died mysteriously on an elevation known as Dead Mountain. Eerie aspects of the incident—unexplained violent injuries, signs that they cut open and fled the tent without proper clothing or shoes, a strange final photograph taken by one of the hikers, and elevated levels of radiation found on some of their clothes—have led to decades of speculation over what really happened.

On the west bank of the Mississippi lies the New Orleans neighborhood of Algiers. Short on hope but big on dreams, its mostly poor and marginalized residents find joy on Friday nights when the Cougars of Edna Karr High School take the field. For years, this football program has brought glory to Algiers, winning three consecutive state championships and sending dozens of young men to college on football scholarships. Although he is preparing for a fourth title, Head Coach Brice Brown is focused on something else: keeping his players alive.

In April of 1846, 21-year-old Sarah Graves, intent on a better future, set out west from Illinois with her new husband, her parents, and eight siblings. Seven months later, after joining a party of pioneers led by George Donner, they reached the Sierra Nevada Mountains as the first heavy snows of the season closed the pass ahead of them. In early December, starving and desperate, Sarah and 14 others set out for California on snowshoes and over the next 32 days endured almost unfathomable hardships and horrors.