Savannah was four years old when her twin sister, Georgia, went missing from their small Louisiana town, fracturing their family. Twenty-eight years later, Savannah convinces her estranged older sisters, Rayanne and Sue Ellen, to honor the pact they made as children and retrieve the time capsule they buried in their old backyard. But coming home means confronting old ghosts…and their stubborn grandmother, Meemaw.

Midwife Patience Murphy has a gift: a talent for escorting mothers through the challenges of bringing children into the world. Working in the hardscrabble conditions of Appalachia during the Depression, Patience takes the jobs that no one else wants, helping those most in need - and least likely to pay. She knows a successful midwifery practice must be built on a foundation of openness and trust - but the secrets Patience is keeping are far too intimate and fragile for her to ever let anyone in.

In the quaint town of Hart's Ridge, Deputy Taylor Gray is a force to be reckoned with. From clawing her way out of poverty and foster care to achieving her dream of being in law enforcement, Taylor is determined to make a difference in her community. When a five-year-old girl named Molly walks into a gas station alone and barely speaking, Taylor's determination is put to the test. As she delves deeper into the investigation, Taylor discovers that even the most idyllic towns have their secrets. But this time, the stakes are higher than ever before.

Del Wensley, wife of the most celebrated preacher in Harlan County, tries to mind her place. Until her husband’s infidelity pushes an already strained marriage to a breaking point. Clinging to her last hope for self-respect, Del turns her back on the rigid life she’s known. A coal train is rolling through the valley. With her eyes wide open to the unfamiliar, and to the freedom she craves, Del takes to the rails.

On Memorial Day in Jewel, Minnesota, the body of wealthy landowner Jimmy Quinn is found floating in the Alabaster River, dead from a shotgun blast. The investigation falls to Sheriff Brody Dern, a highly decorated war hero who still carries the physical and emotional scars from his military service. Even before Dern has the results of the autopsy, vicious rumors begin to circulate that the killer must be Noah Bluestone, a Native American WWII veteran who has recently returned to Jewel with a Japanese wife.

With all his family and friends gone except an estranged grandson, retired Major League ballplayer Murray McBride is looking for a reason to live. He finds it in Jason Cashman, a spirited 10-year-old boy with a terminal heart defect and a list of five things he wants to do before he dies. Murray is determined to help Jason fulfill his dreams. Together, they race against the limited time each has left, ticking off Jason's wishes one by one.

Brooklyn, 1924. As New York City enters the jazz age, the lives of three very different women are about to converge in unexpected ways. Recently arrived from New Orleans, Beatrice is working to establish a chic new dress shop with help from Alice, the orphaned teenage ward she brought north with her. Down the block, newlywed Catherine is restless in her elegant brownstone, longing for a baby she cannot conceive.

Aleen Cust has big dreams. And no one―not her family, society, or the law―will stop her. Born in Ireland in 1868 to an aristocratic English family, Aleen knows she is destined to work with animals, even if her family is appalled by the idea of a woman pursuing a veterinary career. Going against their wishes but with the encouragement of the guardian assigned to her upon her father’s death, Aleen attends the New Veterinary College in Edinburgh, enrolling as A. I. Custance to spare her family the humiliation they fear.

In the ruggedness of the beautiful Kentucky mountains, Honey Lovett has always known that the old ways can make a hard life harder. As the daughter of the famed blue-skinned Troublesome Creek packhorse librarian, Honey and her family have been hiding from the law all her life. But when her mother and father are imprisoned, Honey realizes she must fight to stay free, or risk being sent away for good.

At the end of the Second World War, Cyril Conroy combines luck and a single canny investment to begin an enormous real estate empire, propelling his family from poverty to enormous wealth. His first order of business is to buy the Dutch House, a lavish estate in the suburbs outside of Philadelphia. Meant as a surprise for his wife, the house sets in motion the undoing of everyone he loves. The story is told by Cyril’s son Danny, as he and his older sister, the brilliantly acerbic and self-assured Maeve, are exiled from the house where they grew up by their stepmother.

The great scholar, W. E. B. Du Bois, once wrote about the problem of race in America, and what he called “Double Consciousness,” a sensitivity that every African American possesses in order to survive. Since childhood, Ailey Pearl Garfield has understood Du Bois’s words all too well. Bearing the names of two formidable Black Americans—the revered choreographer Alvin Ailey and her great grandmother Pearl, the descendant of enslaved Georgians and tenant farmers—Ailey carries Du Bois’s problem on her shoulders.

1950s Philadelphia: fifteen-year-old Ruby Pearsall is on track to becoming the first in her family to attend college. But a taboo love affair threatens to pull her back down into the poverty and desperation that has been passed on to her like a birthright. Eleanor Quarles arrives in Washington, DC, with ambition and secrets. When she meets the handsome William Pride at Howard University, they fall madly in love. But William hails from one of DC’s elite wealthy Black families, and his par­ents don’t let just anyone into their fold.

John Russell's heart aches from the loss of his wife, but the Shenandoah Valley frontiersman needs to marry again for his daughter's sake. At first he believes he has found the right young woman, despite their differences, but his faith falters when time reveals she isn't quite what she seemed. Can he truly love her? Unlike her disgraced sister, Abigail Williams obeys the Commandments. At least, she thinks herself a Christian until a buckskin-clad newcomer courts her. He treats her kindly but also introduces her to a sermon by the controversial preacher, George Whitefield.

Nicole Chung couldn’t hightail it out of her overwhelmingly white Oregon hometown fast enough. As a scholarship student at a private university on the East Coast, no longer the only Korean she knew, she found community and a path to the life she'd long wanted. But the middle class world she begins to raise a family in–where there are big homes, college funds, nice vacations–looks very different from the middle class world she thought she grew up in, where paychecks have to stretch to the end of the week, health insurance is often lacking, and there are no safety nets.

It's 1947. War's over, cherry-print dresses, parking above the city lights, swing dancing. Beautiful, 17-year-old Violet lives in a perfect world. Everybody loves her. In 2012, she's still beautiful, charming, and surrounded by admirers. Veronica "Ronni" Johnson, licensed practical nurse and aspiring writer, meets the captivating Violet in the assisted living facility where Violet requires no assistance, just lots of male attention. When she dies, she leaves Ronni a very generous bequest - only if Ronni completes a book about her life within one year.