When a baddie drops out of a sky-high window (Did he jump - heh heh - or was he pushed?), Daily Bugle publisher J. Jonah Jameson wants Spider-Man to take the rap. Has the wall-crawler come to the end of his rope? Does his life hang by a slender thread? To swing clear of this one, he's got to snoop on an international oil conference. There's blackmail! Radioactivity! And a welcoming committee of death-dealing arch-villains!

While visiting Japan, Wolverine is recruited to recover a stolen experimental drug, one that has the potential to be a true miracle cure for all human disease - or a sadistic means of enslaving the world. With every hour bringing mankind closer to tragedy, he embarks on a daring mission to identify the thieves and thwart their terrifying agenda.

Jean Grey awakens in an unfamiliar room. She is weak, disoriented, stripped of her telepathic and telekinetic powers - and trapped in someone else's body. Also prisoner are her teammates Cyclops, Wolverine, Rogue, and Nightcrawler - their minds held hostage within the bodies of strangers. Who has brought them here, and for what purpose? The answers lead to a terrifying plan that threatens not only the X-Men, but all of mutantkind.

The X-Men are mutants—born with extraordinary powers that set them apart from the very humanity they are sworn to protect. Now, groundbreaking research has revealed a method for reversing the genetic mutation responsible for mutant powers—whether the mutant wants it reversed or not. The US government wants to use this procedure to eliminate the so-called mutant menace once and for all—but the X-Men soon learn that the true source of the procedure is their old enemy, Sinister! And his agenda is far more complex and dangerous than even the X-Men can imagine.

A scared teenager on the run. An infant child some say is humanity's savior. A former lover whose life is now hobbled by a terrible secret. A law partner accused of a horrible crime. A city being overcome by an inscrutable menace. They need a guardian. Someone to protect them. Someone with faith in them. They need Daredevil.