Once upon a time, Dr. Emily Nichols—the academic kind, not the physician kind—was an eco-crusader who was shot with water cannons, hunted by poachers, and chased by a bulldozer. Now? Action Emily lives in a bland condo with gray walls and teaches disengaged students at a university alongside a risk-allergic boyfriend, asking herself every day: How did I get here?

Vivian Quackenbush enjoys a typical life. She has winesday evenings with her two best friends. Her son is in college. She and her husband, Mitch, are planning the next move for their empty-nester future. But to Vivian’s blindsided surprise…not together. After nearly twenty-five years of marriage, Mitch wants a divorce. He confesses that he doesn’t love her anymore. He never even liked her chicken salad! Brutal. What is Vivian to do but channel her anger, frustration, and pain into a video she posts online.

When sixteen-year-old Angie Stewart starts hearing a mysterious voice in her house, she’s thrilled at the possibility of a ghost. Finally, something interesting is happening in her boring hometown of East Henderson, Pennsylvania. But why is she the only one who can hear it? And what does it want from her?

Remi Finch has spent the better part of her adult life avoiding family—especially her sisters. They just don’t click. Besides, her unconventional upbringing and major anxiety have convinced Remi that she can’t build a relationship with anyone. Period. When her parents plan a family reunion camping trip to celebrate their anniversary, Remi’s willing to reconnect, if only because she doesn’t have a choice. But then a dead body turns up at their campsite, and their sisterly bonding kicks into high gear.

Prairie Nightingale is both the midlife mother of two teenage girls and a canny entrepreneur who has turned homemaking into a salaried profession. She’s also fascinated with the gritty details of other people’s lives. So when seemingly perfect Lisa Radcliffe, a member of her former mom-friends circle, suddenly disappears, it’s in Prairie’s nature to find out why. Given her innate talent for vital pattern recognition, Prairie is out to catch a few clues by taking a long, hard look at everyone in Lisa’s life—and uncovering their secrets.

In the 1970s, a new wave of feminism was sweeping America. But in the boys’ club of banking and finance, women were still infantilized—no credit without a male cosigner, and their income was dismissed as unreliable. If bankers weren’t going to accommodate women, then women had to take control of their own futures. In 1978 in Denver, Colorado, the opening of the Women’s Bank changed everything.

The next step in Ellie Baker’s marriage: divorce. She and her husband, Jonah, are heading to Florida to break it to the family. No great drama to share. After twenty years of marriage, they’ve just fallen out of love. Simple. Not to their college-age daughter, Maggie, who is devastated. Or to Ellie’s father, Frank, who grows as cold as a retiree can get in Orlando. As for Ellie’s mother, Bunny: no, no, no. She doesn’t want to hear it. After a dreadful weekend, Ellie and Jonah return home to New Jersey with hearts and minds still set on a split.

The last thing Alice expects to see at her husband’s graveside on his birthday is a giant, talking frog. On closer inspection, it’s a grown man dressed as Kermit. Turns out Alice’s husband is buried next to Ben’s older brother Harry, who—as a parting practical joke in his will—insisted that Ben visit his grave each year, on this specific day, dressed in an as-yet-undisclosed pageant of embarrassing fancy dress.

After too many dates, thirtysomething Mimi Perkins is still single, unmoored, and longing for love. So when Ren Yardley—a handsome, divorced fellow drama teacher and single father—falls in love with her and proposes, she’s sure this is at last the good news her psychic predicted. Soon after proposing, Ren receives the devastating news that his ex-wife has been in a debilitating car accident, prompting him to temporarily move back into his former home to care for her and his daughters.

New York City, 1950. Dreams come true for radio personality Maggie Lane when she gets her big break in the exciting new world of television. The Maggie Lane Baking Show is on the air. All she has to do is act like the ideal housewife, create sumptuous desserts, charm the show’s sponsors, and sign a morality clause to ensure that her girl-next-door image remains untarnished. Although newlywed Maggie has never baked so much as a cookie, and knows even less about maintaining a home, keeping up appearances is a necessary ingredient for success. Easy.

Everyone says falling in love is supposed to be easy. But what happens when you meet the perfect man…in your dreams? Especially when you find out he was real and died one year ago–on the bridge you had agreed to meet on for your first date. Wouldn’t you try to go back in time and change the course of destiny to create your very own happy-ever-after? But the path to true love is never without complications, and meddling with the past can have unexpected consequences…

In the same week, Marlen and Hilda’s family receives two significant pieces of news: One, Marlen has been diagnosed with a terminal illness. Two, a cosmic blast is set to render humanity extinct within a matter of months. It seems the coming Christmas on their Saskatchewan farm could be everyone’s last. Preparing for the inevitable, they navigate the time they have left together. Marlen and Hilda channel their energy into improbably prophetic works of art. Hilda’s elderly father receives a longed-for visitor from his past.

Addison Torres has nothing left to lose in New York: no job, no fiancé, no parents to lean on. So when Uncle Arnie offers her a concierge gig in sunny California, she hops on a plane without looking back. Before it all came crashing down, Addison had a matchmaking career and handsome partner—then she got a little too cozy with a client. Digging her way out of the wreckage, she’s taken a strict vow of celibacy. Unfortunately, Addison’s new home is where such promises go to die.

Emma Rini is in a rut so deep she could shelve books there. While her sister awaits her first baby, and her parents kick off retirement with vow renewals and travel, Emma stays put among the stacks of the family bookshop. In fact, she can’t remember the last time she took a vacation. Or had a romance that hovered above disappointing. When her parents assume she’ll take over the shop for them without a break, she realizes she needs to get away—back to the nineteenth century.

As a relationship therapist, Nora helps patients explore their feelings honestly. But she’s hiding an embarrassing relationship secret of her own: she’s in love with someone she’s never even met. J edits the advice column Nora’s been writing anonymously for the last seven years. He’s in London, she’s in New York, and they communicate solely through shared files. When he confides that his girlfriend’s out of the picture, and her boss asks her to come to London, Nora takes both as a sign.