The next step in Ellie Baker’s marriage: divorce. She and her husband, Jonah, are heading to Florida to break it to the family. No great drama to share. After twenty years of marriage, they’ve just fallen out of love. Simple. Not to their college-age daughter, Maggie, who is devastated. Or to Ellie’s father, Frank, who grows as cold as a retiree can get in Orlando. As for Ellie’s mother, Bunny: no, no, no. She doesn’t want to hear it. After a dreadful weekend, Ellie and Jonah return home to New Jersey with hearts and minds still set on a split.

Charlie Tannehill and her twin sister, Maggie, are just eight years old when an unfortunate scientific discovery upends their world—and the world order. The revelation? Extinction, encoded in every creature’s DNA. The expiration date for humans? Only four generations away. A decade later, unsure of what tomorrow holds, Charlie and Maggie enroll as counselors in a government-run human-husbandry program.

For generations, the fortune-telling women in Lo Zhao-Jensen’s family have foreseen The One—the great loves of their lives—before ever meeting them. Except for Lo, who has zero psychic abilities. Just memories of old rom-coms and a lot of poor judgment when it comes to love. Until now. When Lo finally has the vision she’s been waiting for, her delighted aunties are convinced she’ll meet The One on her backpacking trip in Italy. Vero amore, here she comes.

Uncertain of what tomorrow brings, Elliott Holland decides to live it up—on the eve of a stem cell transplant to treat her leukemia. It’s destiny when she crosses paths with handsome and charming Jamie Sullivan. The chemistry is magic. So is a beautiful evening that ends with a bittersweet kiss goodbye and no expectations of ever seeing each other again.

Tig Costello has arrived in Darren, Kentucky, commissioned to paint a portrait honoring her grandfather Benjamin. His contributions to the rural Appalachian town and his unimpeachable war service have made him a local hero. But to Tig, he’s a relative stranger. To find out more about him, Tig wants to talk to the person who knew her grandfather best: Eloise Price, the woman who murdered him fifty years ago.

Cat McCarthy has spent years extricating herself from the family business—an increasingly run-down theater camp—and all the drama contained within it. At thirty-seven, she’s putting the final touches on a new life as she renovates her dream cottage and awaits her first child. Does it worry her that the McCarthy legacy is in the hands of her disastrously irresponsible sister, Ginger? Sure. But the camp’s not Cat’s problem anymore.

On the eve of her wedding to Adam, Lily’s best friend Josh unexpectedly walked out of her life, and she hasn’t seen him since. Lily and Adam are blissfully happy, until he falls ill. As she cares for him in his final hours, Adam asks her to make a mysterious promise: to find Josh—and forgive them both.

Mira Salvi has the perfect life—a job she loves, a fiancé everyone adores, and the secure future she’s always imagined for herself. Really, she hasn’t a thing to complain about, not even when she has to go on her engagement trip to New York alone. While playing tourist in the city, Mira chances upon a lost ring, and her social media post to locate its owner goes viral. With everyone trying to claim the ring, only one person seems to want to find its owner as badly as Mira does: journalist Krish Hale.

Hollywood, 1955. As head costume designer for Lux Pictures, Lena Taylor hears startling confessions from the biggest movie stars. She knows how to keep their secrets—after all, none of their scandals can match her own. Lena was once Elsie Gruner, the daughter of an Ohio dressmaker. Her gift for fashion design helped her win a coveted spot at an art academy in Rome. While in Italy, she became enthralled by the charismatic Julia, who drew her into a shadowy world of jazz clubs, code words, and mysterious deliveries.

Remi Finch has spent the better part of her adult life avoiding family—especially her sisters. They just don’t click. Besides, her unconventional upbringing and major anxiety have convinced Remi that she can’t build a relationship with anyone. Period. When her parents plan a family reunion camping trip to celebrate their anniversary, Remi’s willing to reconnect, if only because she doesn’t have a choice. But then a dead body turns up at their campsite, and their sisterly bonding kicks into high gear.

Vivian Quackenbush enjoys a typical life. She has winesday evenings with her two best friends. Her son is in college. She and her husband, Mitch, are planning the next move for their empty-nester future. But to Vivian’s blindsided surprise…not together. After nearly twenty-five years of marriage, Mitch wants a divorce. He confesses that he doesn’t love her anymore. He never even liked her chicken salad! Brutal. What is Vivian to do but channel her anger, frustration, and pain into a video she posts online.

As a relationship therapist, Nora helps patients explore their feelings honestly. But she’s hiding an embarrassing relationship secret of her own: she’s in love with someone she’s never even met. J edits the advice column Nora’s been writing anonymously for the last seven years. He’s in London, she’s in New York, and they communicate solely through shared files. When he confides that his girlfriend’s out of the picture, and her boss asks her to come to London, Nora takes both as a sign.

Once upon a time, Dr. Emily Nichols—the academic kind, not the physician kind—was an eco-crusader who was shot with water cannons, hunted by poachers, and chased by a bulldozer. Now? Action Emily lives in a bland condo with gray walls and teaches disengaged students at a university alongside a risk-allergic boyfriend, asking herself every day: How did I get here?

Art student Jo Kozak and her fellow classmates and best friends, Caroline, Finch, Amrita, and Saz, are one another’s muses—so close they have their own language and so devoted to the craft that they’ll do anything to keep their inspiration alive. Even if it means naively resorting to the occult to unlock their creativity and to curse their esteemed, if notoriously creepy, professor. They soon learn the horrible price to be paid for such a transgressive ritual.

In the same week, Marlen and Hilda’s family receives two significant pieces of news: One, Marlen has been diagnosed with a terminal illness. Two, a cosmic blast is set to render humanity extinct within a matter of months. It seems the coming Christmas on their Saskatchewan farm could be everyone’s last. Preparing for the inevitable, they navigate the time they have left together. Marlen and Hilda channel their energy into improbably prophetic works of art. Hilda’s elderly father receives a longed-for visitor from his past.

In the 1930s, Germany was a hotbed of scientific thought. But after the Nazis took power, Jewish and female citizens were forced out of their academic positions. Hedwig Kohn, Lise Meitner, Hertha Sponer and Hildegard Stücklen were eminent in their fields, but they had no choice but to flee due to their Jewish ancestry or anti-Nazi sentiments. Their harrowing journey out of Germany became a life-and-death situation that required Herculean efforts of friends and other prominent scientists.

Full of larger than life characters and cinematically written, The Cure for Women documents the birth of a sexist science still haunting us today as the fight for control of women’s bodies and lives continues.

Betty MacDonald was a 28-year-old reporter from Hawaii. Zuzka Lauwers grew up in a tiny Czechoslovakian village and knew five languages by the time she was 21. Jane Smith-Hutton was the wife of a naval attaché living in Tokyo. Marlene Dietrich, the German-American actress and singer, was of course one of the biggest stars of the 20th century. These four women, each fascinating in her own right, together contributed to one of the most covert and successful military campaigns in WWII.

The year was 1917. As a war raged across the world, young American women flocked to work, painting watches, clocks, and military dials with a special luminous substance made from radium. It was a fun job, lucrative and glamorous - the girls themselves shone brightly in the dark, covered head to toe in the dust from the paint. They were the radium girls. As the years passed, the women began to suffer from mysterious and crippling illnesses.

Emma Rini is in a rut so deep she could shelve books there. While her sister awaits her first baby, and her parents kick off retirement with vow renewals and travel, Emma stays put among the stacks of the family bookshop. In fact, she can’t remember the last time she took a vacation. Or had a romance that hovered above disappointing. When her parents assume she’ll take over the shop for them without a break, she realizes she needs to get away—back to the nineteenth century.