Suspicious deaths. Broken bonds. Lives in peril. Redemption. Past-haunted emergency physician Zack Winston and case-hardened defense attorney Bridget Larsen battle a malicious malpractice suit. They uncover a medical conspiracy trading in drugs and murder. As they peel back layers of truth, past relationships and current alliances destabilize-threatening both their lives. A new bond ignites between them.

Twenty-eight-year-old Sean McGillin is the picture of health, until he fractures his leg while in-line skating in New York City's Central Park. Within 24 hours of his surgery, he dies.

Twenty-three-year-old Michael “Mitt” Fuller starts his surgical residency with great anticipation at the nearly three-hundred-year-old, iconic Bellevue Hospital, following in the footsteps of four previous, celebrated Fuller generations. The pressure is on for this newly minted doctor, and to his advantage he’s always had a secret sixth sense, a sensitivity to the nonphysical. But quickly one patient after another assigned to his care begin to die from mysterious causes.

Failed surgeon David McBride is in exile from the surgical community after making a costly error in judgment. Down but not out, he perseveres and is given a second chance to establish a career in surgery. But, as McBride stands on the threshold of a new life, the malignant underside of his fellow man intervenes. Under the threat of violence, David is forced to perform illegal organ harvests in a makeshift operating room hidden in a dilapidated meatpacking warehouse in lower Manhattan.

Sam Johnstone was hoping for renewal when he took a job at a boutique law firm in rustic Wyoming. The mountains and streams of the West would be a refreshing, quiet place to start over after years of war and turmoil in his personal life. But after a local woman is brutally murdered, Sam realizes that things aren’t so quiet in this rural American town. The accused is one Tommy Olsen, a known delinquent who had been sleeping with the victim. Sam is repulsed by the crime and wants nothing to do with the case but meets with Tommy to make sure he has legal representation.

Two little girls stand with their heads bowed in my living room. I’m told they’re my granddaughters. Daisy is nine, and Alice seven. Daisy is the spitting image of her mother. This is the first time I’ve met them since my daughter and I fell out after she married that waste of space, Vince. They’ve come to live with me because their mother — my daughter — was murdered. In her own home while they slept close by. I think Vince killed her. But the police can’t prove it. I’ve always known he was no good. He treated my daughter like dirt. I said he’d cheat on her — but she wouldn’t listen.

Lowen Ashleigh is a struggling writer on the brink of financial ruin when she accepts the job offer of a lifetime. Jeremy Crawford, husband of best-selling author Verity Crawford, has hired Lowen to complete the remaining books in a successful series his injured wife is unable to finish. Lowen arrives at the Crawford home, ready to sort through years of Verity's notes and outlines, hoping to find enough material to get her started. What Lowen doesn't expect to uncover in the chaotic office is an unfinished autobiography Verity never intended for anyone to read.

Who is Audrey Hoedemaker? It's a question her sister Maureen has heard more times than she can count, and she doesn't know what the short answer would be. Little sister, troubled teen, backpacker, musical theatre coach, con artist, childcare worker. Murderer. A tragic, traumatic childhood casts a long shadow on the Hoedemaker sisters. Maureen has worked hard to move beyond the violence of the past and build a good, honest life for herself. Audrey, however, just can't seem to do the same, careening from one state of chaos to another.

After the killing of a prominent mob lawyer, NYPD homicide detectives Jacob Jackson and Caitlin Grimes start receive chilling, written “rules” for how to commit the perfect murder. "Rule number one for the perfect murder: Evidence is your enemy. Leave none behind." Jackson (Reid Scott) and Grimes (Cobie Smulders) race to find the killer, setting them on a collision course with the city’s crime underbelly, and a perpetrator who seems happy to toy with them. “Rule number two. No crimes of passion. The perfect murder is always business, never pleasure.”

It’s 1984, and life has changed beyond recognition. Airstrip One, formerly known as Great Britain, is a place where Big Brother is always watching, and nobody can hide. Except, perhaps, for Winston Smith. Whilst working at the Ministry of Truth, rewriting history, he secretly dreams of freedom. And in a world where love and sex are forbidden, where it’s hard to distinguish between friend and foe, he meets Julia and O’Brien and vows to rebel.