Dr. Jacey Flanigan has worked tirelessly to achieve her dream of becoming a pediatric cardiologist. But when she moves to Manhattan to begin her career at a prestigious children's hospital, she discovers that the medical profession may not be what she expected. An encounter with an arrogant heart surgeon on her first day sets the tone for what's to come - a world of enigmatic physician behavior and questionable cardiac surgical practices cloaked in secrecy.

Dr. Jack Wyatt is renowned for solving the unsolvable. When a colleague approaches him about a dangerous new malady affecting only Leukemia patients at a prestigious oncology hospital, the mysterious case is too intriguing to pass up. So he and the brilliant Dr. Madison Shaw, a physician who shares not only his expertise but also his devotion to medicine, embark in a race against time to save the children as cases mount. Within the hospital walls, they confront a labyrinth of medical conundrums, hostile colleagues guarding their territory, and a web of political intrigue.

DC Heart surgeon Dr. Steven Leeds is suddenly besieged by a handful of immensely complicated heart attack and stroke cases, all caused by a rare arterial injury—a dissection. Private detective Kirk Miner and FBI agent Jack Mulville investigate, and they immediately suspect Leeds’ former lover, who harbors a grudge against all the victims. Then when prominent people in the US government begin to experience these same deadly cardiac emergencies, it falls to the unlikely team of three to snuff out a catastrophic plot that only the medically astute can divine.

As if her life wasn't complicated enough, people start dropping like flies in her rural ER. As she looks for the cause, she gets caught in a web of deception and death, threatening everything she loves. Using her courage and medical knowledge, Emma fights the fight of her life to protect those she holds dear. Will she destroy the evil, or will it crush her first?

Across the Pacific Northwest, a twisted killer stalks victims representing ancient archetypes: The Ruler. The Warrior. The Scholar. The Priest. Four are dead, leaving FBI investigators puzzled by the macabre, color-coded shrines the killer left behind. And clues now point to a fifth victim.

When her elderly patients start dying at home days after minor surgery, anesthesiologist Dr. Kate Downey wants to know why. The surgeon, not so much. “Old people die, that’s what they do,” is his response. When Kate presses, surgeon Charles Ricken places the blame squarely on her shoulders. Kate is currently on probation, and the chief of staff sides with the surgeon, leaving Kate to prove her innocence and save her own career. With her husband in a prolonged coma, it’s all she has left.

Dr. Mallory Hayes, a Centers for Disease Control and Prevention (CDC) medical investigator, is a committed physician and researcher quietly battling height and air-flight anxiety. When a tsunami devastates the coast of Southern California, the Federal Emergency Management Agency (FEMA) establishes a camp to house the tens of thousands of people displaced by the disaster, and the Army is brought in to provide medical services.

Special Agent Constant Marlowe is tasked with taking over the investigation of an obsessed serial killer trolling the small town of Clark Valley in the quiet—and eerie—plains of the Midwest. Two female victims in quick succession, the same brutal MO, and every indication that victim number three is only days away. Also in the killer’s scope is Constant herself. When she interviews a local family who may be potential witnesses, she leads the devil to their doorstep, throwing their lives into chaos.

Twenty-three-year-old Michael “Mitt” Fuller starts his surgical residency with great anticipation at the nearly three-hundred-year-old, iconic Bellevue Hospital, following in the footsteps of four previous, celebrated Fuller generations. The pressure is on for this newly minted doctor, and to his advantage he’s always had a secret sixth sense, a sensitivity to the nonphysical. But quickly one patient after another assigned to his care begin to die from mysterious causes.

Thomas Austin was once a prominent NYPD detective, known for locking up a psychopathic serial killer dubbed "The Holiday Baby Butcher". Now retired in a small beach town in the Pacific Northwest, Austin runs a little café, trying to overcome the loss of his wife, a DA who was gunned down only one year ago.

After she and her new friend, Tim Brown, gain entrance into this dream school, everything soon becomes a waking nightmare as student after student begins behaving as if they were brainwashed. Now Quinn and Tim must hurry to uncover the dark truth before it's too late . . .

Brooklyn Sloane works as a special consultant to the FBI as one of the most adept profilers in the agency's history. She had been recruited at a relatively young age from her career in academics, but her colleagues have no idea the disturbing motive for her success.

Inside Boston Doctors Hospital, patients are dying. In the glare of the operating room, they survive the surgeon's knife. But in the dark, hollow silence of the night, they die. Suddenly, inexplicably, horribly. A tough, bright doctor will risk his very life for a dedicated young nurse who unknowingly holds the answers.

Dr. Julie Devereux is an outspoken advocate for the right to die - until a motorcycle accident leaves her fiancé, Sam Talbot, a quadriplegic. Sam begs to end his life, but Julie sees hope in a life together. With the help of an organization that opposes physician-assisted suicide, Julie has Sam coming around to her point of view when he suddenly dies from an unexpected heart attack.

This trial should be a slam-dunk. A faceless powerbroker has other ideas.... Small-town prosecutor Mara Brent must be tough as nails to succeed in her male-dominated profession. But she harbors a soft spot for the victims who rely on her courtroom skill, especially the wheelchair-bound rape survivor she’s known since her first day on the job. So when her friend’s unsolved case reopens with a DNA match and an arrest, she’s determined to finally bring a monster to justice.

Two little girls stand with their heads bowed in my living room. I’m told they’re my granddaughters. Daisy is nine, and Alice seven. Daisy is the spitting image of her mother. This is the first time I’ve met them since my daughter and I fell out after she married that waste of space, Vince. They’ve come to live with me because their mother — my daughter — was murdered. In her own home while they slept close by. I think Vince killed her. But the police can’t prove it. I’ve always known he was no good. He treated my daughter like dirt. I said he’d cheat on her — but she wouldn’t listen.

Lowen Ashleigh is a struggling writer on the brink of financial ruin when she accepts the job offer of a lifetime. Jeremy Crawford, husband of best-selling author Verity Crawford, has hired Lowen to complete the remaining books in a successful series his injured wife is unable to finish. Lowen arrives at the Crawford home, ready to sort through years of Verity's notes and outlines, hoping to find enough material to get her started. What Lowen doesn't expect to uncover in the chaotic office is an unfinished autobiography Verity never intended for anyone to read.

Who is Audrey Hoedemaker? It's a question her sister Maureen has heard more times than she can count, and she doesn't know what the short answer would be. Little sister, troubled teen, backpacker, musical theatre coach, con artist, childcare worker. Murderer. A tragic, traumatic childhood casts a long shadow on the Hoedemaker sisters. Maureen has worked hard to move beyond the violence of the past and build a good, honest life for herself. Audrey, however, just can't seem to do the same, careening from one state of chaos to another.

After the killing of a prominent mob lawyer, NYPD homicide detectives Jacob Jackson and Caitlin Grimes start receive chilling, written “rules” for how to commit the perfect murder. "Rule number one for the perfect murder: Evidence is your enemy. Leave none behind." Jackson (Reid Scott) and Grimes (Cobie Smulders) race to find the killer, setting them on a collision course with the city’s crime underbelly, and a perpetrator who seems happy to toy with them. “Rule number two. No crimes of passion. The perfect murder is always business, never pleasure.”

Kidnappers grabbed Jenna in broad daylight, right in front of her children and their horrified classmates. Her family was issued an insane ransom demand: $25 million in cash and jewels, payable by the end of the school day, otherwise they’ll never see her again. As Jenna’s mother scrambles to gather the money, detectives Mo Butler and George Ortega follow the trail of the kidnappers, which will lead them through a sordid landscape of jealous lovers, broken dreamers, and twisted schemers. But every second counts, and there’s one thing Jenna Wade doesn’t have: very much time.

When her elderly patients start dying at home days after minor surgery, anesthesiologist Dr. Kate Downey wants to know why. The surgeon, not so much. “Old people die, that’s what they do,” is his response. When Kate presses, surgeon Charles Ricken places the blame squarely on her shoulders. Kate is currently on probation, and the chief of staff sides with the surgeon, leaving Kate to prove her innocence and save her own career. With her husband in a prolonged coma, it’s all she has left.

DC Heart surgeon Dr. Steven Leeds is suddenly besieged by a handful of immensely complicated heart attack and stroke cases, all caused by a rare arterial injury—a dissection. Private detective Kirk Miner and FBI agent Jack Mulville investigate, and they immediately suspect Leeds’ former lover, who harbors a grudge against all the victims. Then when prominent people in the US government begin to experience these same deadly cardiac emergencies, it falls to the unlikely team of three to snuff out a catastrophic plot that only the medically astute can divine.

Dr. Jacey Flanigan has worked tirelessly to achieve her dream of becoming a pediatric cardiologist. But when she moves to Manhattan to begin her career at a prestigious children's hospital, she discovers that the medical profession may not be what she expected. An encounter with an arrogant heart surgeon on her first day sets the tone for what's to come - a world of enigmatic physician behavior and questionable cardiac surgical practices cloaked in secrecy.

As if her life wasn't complicated enough, people start dropping like flies in her rural ER. As she looks for the cause, she gets caught in a web of deception and death, threatening everything she loves. Using her courage and medical knowledge, Emma fights the fight of her life to protect those she holds dear. Will she destroy the evil, or will it crush her first?

Dr. Carrie Bryant's four years as a neurosurgical resident at White Memorial Hospital have earned her the respect and admiration from peers and staff alike. When given the chance of performing her first unsupervised brain surgery, Carrie jumps at the opportunity. What should have been a routine, hours-long operation turns horribly wrong and jeopardizes her patient's life. Emotionally and physically drained, Carrie is rushed back to the OR to assist in a second surgery.

Dr. Jack Wyatt is renowned for solving the unsolvable. When a colleague approaches him about a dangerous new malady affecting only Leukemia patients at a prestigious oncology hospital, the mysterious case is too intriguing to pass up. So he and the brilliant Dr. Madison Shaw, a physician who shares not only his expertise but also his devotion to medicine, embark in a race against time to save the children as cases mount. Within the hospital walls, they confront a labyrinth of medical conundrums, hostile colleagues guarding their territory, and a web of political intrigue.

When Dr. John Meacham goes on a shooting spree the office, his business partner, staff, and two patients are killed in the bloodbath. Then Meacham turns the gun on himself. The blame falls on Dr. Lou Welcome. Welcome worked with Meacham years before as a counselor after John's medical license had been revoked for drug addiction. Lou knew that John was an excellent doctor and deserved to be practicing medicine and fought hard for his license to be restored.

When San Francisco–based FDA epidemiologist Dr. Carrie Hediger uncovers a rash of unexplained deaths while investigating the suspiciously convenient death of her best friend, she becomes determined to find answers—even if it leads her to a murderer, and even if confronting authority, using her wiles, and bending the rules to get justice risks her future in the FDA. To unravel the puzzle, Carrie assembles a team: some talented post-doctoral fellows, a quirky pharmacologist, an unctuous chemist, and a skeptical FBI agent that she can’t help her attraction for.

DS George Cross can be rude, difficult and awkward with people. But his unfailing logic and dogged pursuit of the truth means his conviction rate is the best on the force. So when his police colleagues dismiss the death of a man as a squabble among Bristol's homeless community, Detective Sergeant George Cross is not convinced.

Running away from a past she’d rather forget, Doctor Alison Wilson has moved to a new town to take up the role of Medical Officer at failing hospital St Margaret’s. Tasked with shaking things up, she quickly learns that things are worse than they initially seem: patient records are in disarray, staff morale is low, and there’s something afoot that she can’t quite put her finger on As Alison starts to dig into the hospital’s past, she gradually discovers a trail of lies that runs deeper and darker than she could have ever imagined.

Kate Bennett - a bright hospital pathologist with a loving husband and a solid future. Until one day her world turns dark. A strange, puzzling illness has killed two women. Now it endangers Kate's closest friend. Soon it will threaten Kate's marriage. Her sanity. Her life. Kate has uncovered a horrifying secret. Important people will stop at nothing to protect it. It is a terrifying medical discovery. And its roots lie in one of the greatest evils in the history of humankind.

Dr. Brian Holbrook - former football star and disgraced chief of cardiology - is given the chance of a lifetime when he gets a call from the prestigious Boston Heart Institute. They need him to join an elite team testing the new miracle drug Vasclear. With his father suffering from a dangerous heart condition, Holbrook seizes the opportunity to save his reputation, and also his father's life. However, when patients start dying mysteriously, and colleagues begin to disappear, it's up to Holbrook to find the truth before it's too late.

When Dr. Tom More (of Love in the Ruins) is released on parole from state prison, he returns to Feliciana, Louisiana, the parish where he was born and bred, and where he practiced psychiatry before his arrest. Upon arriving, he notices something strange in almost everyone around him: unusual sexual behavior in women patients, a bizarre loss of inhibition, a lack of complexity in speech - even his own wife’s extraordinary success at bridge tournaments, during which her mind seems to function like a computer.

After she and her new friend, Tim Brown, gain entrance into this dream school, everything soon becomes a waking nightmare as student after student begins behaving as if they were brainwashed. Now Quinn and Tim must hurry to uncover the dark truth before it's too late . . .

Here, Michael Palmer has created a cat-and-mouse game where one woman must confront a conspiracy of doctors to uncover an evil practice that touches every single person who ever has a medical test. With unforgettable characters and twists and betrayals that come from the most unlikely places, The Second Opinion will keep you guessing...and looking over your shoulder.