Twenty-eight-year-old Sean McGillin is the picture of health, until he fractures his leg while in-line skating in New York City's Central Park. Within 24 hours of his surgery, he dies.

DC Heart surgeon Dr. Steven Leeds is suddenly besieged by a handful of immensely complicated heart attack and stroke cases, all caused by a rare arterial injury—a dissection. Private detective Kirk Miner and FBI agent Jack Mulville investigate, and they immediately suspect Leeds’ former lover, who harbors a grudge against all the victims. Then when prominent people in the US government begin to experience these same deadly cardiac emergencies, it falls to the unlikely team of three to snuff out a catastrophic plot that only the medically astute can divine.

Dr. Carrie Bryant's four years as a neurosurgical resident at White Memorial Hospital have earned her the respect and admiration from peers and staff alike. When given the chance of performing her first unsupervised brain surgery, Carrie jumps at the opportunity. What should have been a routine, hours-long operation turns horribly wrong and jeopardizes her patient's life. Emotionally and physically drained, Carrie is rushed back to the OR to assist in a second surgery.

When President Geoffrey Hilliard’s son Cam, a 16-year-old chess champion, experiences extreme fatigue, moodiness, and an uncharacteristic violent outburst, doctors are quick to dismiss his troubles as teen angst. But Secret Service agent Karen Ray summons her physician ex-husband for a second opinion. Dr. Lee Blackwood’s concerns are dismissed by the president's team - until Cam gets sicker. Lee must make a diagnosis from a puzzling array of symptoms he's never seen before. His only clue is a patient named Susie Banks, a young musical prodigy who seems to be suffering from the same baffling condition as Cam.

When her elderly patients start dying at home days after minor surgery, anesthesiologist Dr. Kate Downey wants to know why. The surgeon, not so much. “Old people die, that’s what they do,” is his response. When Kate presses, surgeon Charles Ricken places the blame squarely on her shoulders. Kate is currently on probation, and the chief of staff sides with the surgeon, leaving Kate to prove her innocence and save her own career. With her husband in a prolonged coma, it’s all she has left.

Returning to practice after a suspension for stealing opioids, a young doctor takes the only job he can find: a post as a physician at the struggling St. Luke's Hospital in east London. Amid the maelstrom of sick patients, overworked staff and underfunded wards, a more insidious secret soon declares itself: too many patients are dying. And a murderer may be lurking in plain sight.

After she and her new friend, Tim Brown, gain entrance into this dream school, everything soon becomes a waking nightmare as student after student begins behaving as if they were brainwashed. Now Quinn and Tim must hurry to uncover the dark truth before it's too late . . .

Dr. Toby Harper works the night shift in an emergency room. She spends her daytime hours alone with her mother who suffers from Alzheimer's disease. When elderly Alzheimer's patients from the same retirement home start dying mysteriously, Toby is the only one suspicious enough to investigate. As a result she finds herself, her mother, and her own sanity at risk.

For San Francisco’s newest medical examiner, Dr. Jessie Teska, it was supposed to be a fresh start. A new job in a new city. A way to escape her own dark past. Instead, she faces a chilling discovery when an opioid-overdose case contains hints of something more sinister. Jessie’s superiors urge her to close the case, but as more bodies land on her autopsy table, she uncovers a constellation of deaths that point to an elaborate plot involving drug dealers and Bitcoin brokers.

Dr. Julie Devereux is an outspoken advocate for the right to die - until a motorcycle accident leaves her fiancé, Sam Talbot, a quadriplegic. Sam begs to end his life, but Julie sees hope in a life together. With the help of an organization that opposes physician-assisted suicide, Julie has Sam coming around to her point of view when he suddenly dies from an unexpected heart attack.

In the tightly knit world of Boston medicine, the Randall family reigns supreme. When heart surgeon J. D. Randall’s teenage daughter dies during a botched abortion, the medical community threatens to explode. Was it malpractice? A violation of the Hippocratic Oath? Or was Karen Randall murdered in cold blood? The natural suspect is Arthur Lee, a brilliant surgeon and known abortionist, who has been carrying out the illegal procedure with the help of pathologist John Berry.

The master of medical suspense brings us another novel of controversy, biology, and human greed. Internist Matt Rutledge has spent the last five years trying to find links between the deaths of his wife and his father. He suspects the Belinda Coke and Coal Company has released toxic chemicals into the environment that have caused the "Belinda Syndrome," a miasma of symptoms that include violent and deadly paranoia in some, Ebola-like hemorrhaging in others. But he lacks proof.

Someone is stalking the UCLA Medical Center - a depraved madman who is preying upon the staff, particularly those who are young and female. No stranger to the terrible ravages of senseless violence, E.R. Chief Dr. David Spier must keep the emergency room running smoothly and efficiently, even as his terrified co-workers wonder who will be the next victim. But when the monster himself is dragged into the E.R. in handcuffs - hideously burned, suffering, and begging for mercy - the nightmare is far from over. It has only just begun.

Dr. Mallory Hayes, a Centers for Disease Control and Prevention (CDC) medical investigator, is a committed physician and researcher quietly battling height and air-flight anxiety. When a tsunami devastates the coast of Southern California, the Federal Emergency Management Agency (FEMA) establishes a camp to house the tens of thousands of people displaced by the disaster, and the Army is brought in to provide medical services.

Attorney Nate Shepherd left a big firm to go out on his own. He sees nothing but opportunity when an out-of-town lawyer wants to hire him as local counsel on a high-profile murder case. Though his family worries that the case hits too close to home, Nate joins the defense team. When circumstances force him to take on a bigger role, Nate ignores his family’s fears and throws himself into his client’s defense.

Growing up abandoned by her father and raised by a single mother, Celeste was determined to create the perfect family - but even perfect families have secrets. Her days are filled with a rewarding career, a devoted husband, and her four-year-old daughter. Celeste is the only one who knows the precarious house of cards her family is built upon - until the day her daughter falls critically ill. Then her world quickly spirals out of control, her secret threatening to destroy her marriage, family, reputation, and sanity.

"Something is murdering my men." Thus reads the message received from a Nazi commander stationed in a small castle high in the remote Transylvanian Alps. Invisible and silent, the enemy selects one victim per night, leaving the bloodless and mutilated corpses behind to terrify its future victims. When an elite SS extermination squad is dispatched to solve the problem, the men find something that's both powerful and terrifying. Panicked, the Nazis bring in a local expert on folklore - who just happens to be Jewish - to shed some light on the mysterious happenings.

After almost 20 years together, Stella and Simon are starting to run into problems. An up-and-coming rock musician when they first met, Simon has been clinging to dreams of fame even as the possibility of it has grown dimmer, and now that his band might finally be on the brink again, he wants to go on the road, leaving Stella behind.

Imagine a young doctor, trained in the latest medical knowledge and state-of-the-art equipment, suddenly transported back to one of the world’s most isolated and unforgiving environments - Nome, Alaska. That’s what happen to Dr. Sims. His plans to become a pediatric surgeon were drastically changed when, on the eve of being drafted into the army to serve as a MASH surgeon in Vietnam, he was offered a commission in the US Public Health for assignment in Anchorage, Alaska, where he was scheduled to act as chief of pediatrics at the Alaska Native Medical Center.

Assistant District Attorney Elizabeth Holt has spent over a decade fighting for justice, but when DNA evidence cracks a cold case will justice finally be served? Someone is watching. Just months from her college graduation, Elizabeth Holt is in love and her future is brighter than the sun. But all that changes when, after a romantic birthday with her fiancée, Elizabeth returns home, unaware a secret watcher has unimaginably horrible plans for her.

Four years ago, 19-year-old Travis Brown made a choice: to raise his newborn daughter on his own. While most of his friends were out partying and meeting girls, Travis was at home, changing diapers and worrying about keeping food on the table. But he's never regretted his decision. Bella is the light of his life. The reason behind every move he makes. And so far, she is fed. Cared for. Safe. But when Travis loses his construction job and his home, the security he's worked so hard to create for Bella begins to crumble....

In an idyllic Los Angeles neighborhood, where generations enjoy deep roots in old homes, the O’Rourke family fits right in. Miriam and Craig are both artists and their four children carry on the legacy. When their teenage son, Nick, is diagnosed with schizophrenia, a tumultuous decade ensues in which the family careens off the conventional course. Like the 10 Biblical plagues, they are hit by one catastrophe after another: violence, evictions, arrests, a suicide attempt, a near-drowning - even cancer and a brain tumor - play against the backdrop of a wild teenage bacchanal.

Laya Marston’s husband, Cameron, a daredevil enthusiast, was the complete opposite of her, ready and willing to dive off a cliff-face or parachute across a canyon - and Laya loved him for it. But she was different: pragmatic, regimented, devoted to her career and to supporting Cameron from the sidelines of his death-defying feats. Opposites attract, right? But when Cameron dies tragically, Laya becomes lost in denial, living in the delusion that Cameron will come back to her.

Maya and Rebecca Ward are both accomplished physicians, but that's where the sisters' similarities end. As teenagers, they witnessed their parents' murder, but it was Rebecca who saved Maya from becoming another of the gunman's victims. The tragedy left Maya cautious and timid, settling for a sedate medical practice with her husband, Adam, while Rebecca became the risk taker.

Heather is pale and thin, seventeen and pregnant with twins when Patricia Harman begins to care for her. Over the course of the next five seasons Patsy will see Heather through the loss of both babies and their father. She will also care for her longtime patient Nila, pregnant for the eighth time and trying to make a new life without her abusive husband. And Patsy will try to find some comfort to offer Holly, whose teenage daughter struggles with bulimia. She will help Rebba learn to find pleasure in her body and help Kaz transition into a new body.