Nothing is simple for the men and women in Donald Antrim’s stories. As they do the things we all do - bum a cigarette at a party, stroll with a girlfriend down Madison Avenue, take a kid to the zoo - they’re confronted with their own uncooperative selves. These artists, writers, lawyers, teachers, and actors make fools of themselves, spiral out of control, have delusions of grandeur, despair, and find it hard to imagine a future. They talk, they listen, they hope, they dream.

A work of great personal courage and a literary tour de force, this bestseller is Styron's true account of his experience of crippling depression. Styron is perhaps the first writer to convey the full terror of depression's psychic landscape, as well as the illuminating path to recovery.

The last time Clancy Martin tried to kill himself was in his basement with a dog leash. It was one of over ten attempts throughout the course of his life. But he didn’t die, and like many who consider taking their own lives, he hid the attempt, slipping back into his daily life with a hoarse voice, a raw neck, and vague explanations. In How Not to Kill Yourself, Martin chronicles his suicide attempts in an intimate depiction of the mindset of someone obsessed with self-destruction. The result is a work that powerfully gives voice to what to many has long been incomprehensible.

With uncommon humanity, candor, wit, and erudition, National Book Award winner Andrew Solomon takes the listener on a journey of incomparable range and resonance into the most pervasive of family secrets. The Noonday Demon examines depression in personal, cultural, and scientific terms. Drawing on his own struggles with the illness and interviews with fellow sufferers, doctors and scientists, policymakers and politicians, drug designers and philosophers, Solomon reveals the subtle complexities and sheer agony of the disease.

Amy Bloom began to notice changes in her husband, Brian: He retired early from a new job he loved; he withdrew from close friendships; he talked mostly about the past. Suddenly, it seemed there was a glass wall between them, and their long walks and talks stopped. Their world was altered forever when an MRI confirmed what they could no longer ignore: Brian had Alzheimer’s disease.

“Any story that starts will also end.” As a writer, Ann Patchett knows what the outcome of her fiction will be. Life, however, often takes turns we do not see coming. Patchett ponders this truth in these wise essays that afford a fresh and intimate look into her mind and heart.

One of the most influential works of this century, The Myth of Sisyphus and Other Essays is a crucial exposition of existentialist thought. Influenced by works such as Don Juan and the novels of Kafka, these essays begin with a meditation on suicide; the question of living or not living in a universe devoid of order or meaning.

Jennifer Egan’s spellbinding interlocking narratives circle the lives of Bennie Salazar, an aging former punk rocker and record executive, and Sasha, the passionate, troubled young woman he employs. Although Bennie and Sasha never discover each other’s pasts, the listener does, in intimate detail, along with the secret lives of a host of other characters whose paths intersect with theirs, over many years, in locales as varied as New York, San Francisco, Naples, and Africa.

In a powerful and gripping debut, Rachel Aviv raises fundamental questions about how we understand ourselves in periods of crisis and distress. Drawing on deep, original reporting as well as unpublished journals and memoirs, Aviv writes about people who have come up against the limits of psychiatric explanations for who they are. Animated by a profound sense of empathy, Aviv’s exploration is refracted through her own account of living in a hospital ward at the age of six and meeting a fellow patient with whom her life runs parallel—until it no longer does.

Lillian and Madison were unlikely roommates and yet inseparable friends at their elite boarding school. But then, Lillian had to leave the school unexpectedly in the wake of a scandal, and they’ve barely spoken since. Until now, when Lillian gets a letter from Madison pleading for her help. Madison’s twin stepkids are moving in with her family, and she wants Lillian to be their caretaker. However, there’s a catch: The twins spontaneously combust when they get agitated, flames igniting from their skin in a startling but beautiful way.

In the summer after graduating from college, Suleika Jaouad was preparing, as they say in commencement speeches, to enter “the real world”. She had fallen in love and moved to Paris to pursue her dream of becoming a war correspondent. The real world she found, however, would take her into a very different kind of conflict zone. It started with an itch - first on her feet, then up her legs, like a thousand invisible mosquito bites. Then a trip to the doctor and, a few weeks shy of her 23rd birthday, a diagnosis: leukemia, with a 35 percent chance of survival.

A silent epidemic of chronic illnesses afflicts tens of millions of Americans: These are diseases that are poorly understood, frequently marginalized, and can go undiagnosed and unrecognized altogether. Renowned writer Meghan O’Rourke delivers a revelatory investigation into this elusive category of “invisible” illness that encompasses autoimmune diseases, post-treatment Lyme disease syndrome, and now long COVID, synthesizing the personal and the universal to help all of us through this new frontier.

As Melissa Bond raises her infant daughter and a special-needs one-year-old son, she suffers from unbearable insomnia, sleeping an hour or less each night. She loses her job as a journalist (a casualty of the 2008 recession), and her relationship with her husband grows distant. Her doctor casually prescribes benzodiazepines—a family of drugs that includes Xanax, Valium, Klonopin, Ativan—and increases her dosage regularly.

Called "a masterpiece" by The Guardian, this courageous and honest trilogy from Tove Ditlevsen, a pioneer in the field of genre-bending confessional writing, explores themes of family, sex, motherhood, abortion, addiction, and being an artist. This program contains all three volumes of her memoirs.

Growing up in the 1960s in the suburbs of Chicago, Meg Kissinger’s family seemed to live a charmed life. With eight kids and two loving parents, the Kissingers radiated a warm, boisterous energy. Whether they were spending summer days on the shores of Lake Michigan, barreling down the ski slopes, or navigating the trials of their Catholic school, the Kissingers always knew how to live large and play hard. But behind closed doors, a harsher reality was unfolding.

In an idyllic Los Angeles neighborhood, where generations enjoy deep roots in old homes, the O’Rourke family fits right in. Miriam and Craig are both artists and their four children carry on the legacy. When their teenage son, Nick, is diagnosed with schizophrenia, a tumultuous decade ensues in which the family careens off the conventional course. Like the 10 Biblical plagues, they are hit by one catastrophe after another: violence, evictions, arrests, a suicide attempt, a near-drowning - even cancer and a brain tumor - play against the backdrop of a wild teenage bacchanal.

When her earliest childhood friend is diagnosed with a terminal illness, Becker sets off on a quest to immerse herself in what it means to be mortal. Can we live our lives more fully knowing some day we will die? With a keen eye toward that which makes life worth living, interfaith minister, mom, and perpetual seeker Barbara Becker recounts stories where life and death intersect in unexpected ways.

When their only child was diagnosed with cystic fibrosis (CF) at the age of two, Maryanne O'Hara and her husband were told that Caitlin could live a long life or be dead in a matter of months. Thirty-one years later, Caitlin lost her battle with this devastating disease following an excruciating two-year wait on the transplant list and a last-minute race to locate a pair of healthy lungs. The sudden spiral of events left Maryanne in an existential crisis, searching to find an answer to the eternal question: Why we are here?

Like so many of us, award-winning writer Katy Butler always assumed her aging parents would experience healthy, active retirements before dying peacefully at home. Then her father suffered a stroke that left him incapable of easily finishing a sentence or showering without assistance. Her mother was thrust into full-time caregiving, and Katy became one of the 24 million Americans who help care for aging parents. In an effort to correct a minor and non - life threatening heart arrhythmia, doctors outfitted her father with a pacemaker.

In I’m Telling the Truth, but I’m Lying, Bassey Ikpi explores her life - as a Nigerian-American immigrant, a black woman, a slam poet, a mother, a daughter, an artist - through the lens of her mental health and diagnosis of bipolar II and anxiety. Her remarkable memoir in essays implodes our preconceptions of the mind and normalcy as Bassey bares her own truths and lies for us all to behold with radical honesty and brutal intimacy.

In this tense, gripping novel by a star of Korean literature, Oghi wakes from a coma after causing a devastating car accident that took his wife's life and left him paralyzed and badly disfigured. His caretaker is his mother-in-law, a widow grieving the loss of her only child. Oghi is neglected and left alone in his bed. His world shrinks to the room he lies in and his memories of his troubled relationship with his wife, a sensitive, intelligent woman who found all of her life goals thwarted except for one: cultivating the garden in front of their house.

In the late 1990s, a young physician in Albuquerque, New Mexico, published a stunning memoir of his experiences in the highly charged world of the ER. Presented in a series of powerful, poetic vignettes, The Blood of Strangers became an instant classic. Now, over two decades later, Dr. Frank Huyler delivers another dispatch from the trenches—this time from the perspective of middle age. In portraits visceral, haunting, sometimes surreal, Huyler reveals the gritty reality of medicine practiced on the razor’s edge between life and death.

Chika Jeune was born three days before the devastating earthquake that decimated Haiti in 2010. She spent her infancy in a landscape of extreme poverty, and when her mother died giving birth to a baby brother, Chika was brought to The Have Faith Haiti Orphanage that Albom operates in Port Au Prince. With no children of their own, the 40-plus children who live, play, and go to school at the orphanage have become family to Mitch and his wife, Janine. But at age five, Chika is suddenly diagnosed with something a doctor there says "no one in Haiti can help you with."

This Close to Happy is the rare, vividly personal account of what it feels like to suffer from clinical depression, written from a woman's perspective and informed by an acute understanding of the implications of this disease over a lifetime. Taking off from essays on depression she has written for The New Yorker and The New York Times Magazine, Daphne Merkin casts her eye back to her beginnings to try to sort out the root causes of her affliction.

The shark attacked while she was snorkeling, tearing through Micki Glenn’s breast and shredding her right arm. Her husband, a surgeon, saved her life on the spot, but when she was safely home she couldn’t just go on with her life. She had entered an even more profound survival journey: the aftermath. The survival experience changes everything because it invalidates all your previous adaptations, and the old rules don’t apply. In some cases survivors suffer more in the aftermath than they did during the actual crisis. In all cases, they have to work hard to reinvent themselves.

Writer Karla Cornejo Villavicencio was on DACA when she decided to write about being undocumented for the first time using her own name. It was right after the election of 2016, the day she realized the story she'd tried to steer clear of was the only one she wanted to tell. So she wrote her immigration lawyer's phone number on her hand in Sharpie and embarked on a trip across the country to tell the stories of her fellow undocumented immigrants—and to find the hidden key to her own.

With a play opening on Broadway, and every reason to smile, Sarah Ruhl has just survived a high-risk pregnancy when she discovers the left side of her face is completely paralyzed. She is assured that 90 percent of Bell’s palsy patients experience a full recovery—like Ruhl’s own mother. But Sarah is in the unlucky ten percent. And for a woman, wife, mother, and artist working in theater, the paralysis and the disconnect between the interior and exterior brings significant and specific challenges.

When 39-year-old Maria Forssmann wakes up in her 17-year-old body, she doesn’t know how she got there. All she does know is she has to get back: to her home in Bienville, Mississippi, to her job as a successful psychiatrist and, most importantly, to her husband, daughters, and unborn son.

Families are riddled with untold secrets. But Stephen Hinshaw never imagined that a profound secret was kept under lock and key for 18 years within his family - that his father's mysterious absences, for months at a time, resulted from serious mental illness and involuntary hospitalizations. From the moment his father revealed the truth, during Hinshaw's first spring break from college, he knew his life would change forever.

In The Trip to Echo Spring, Olivia Laing examines the link between creativity and alcohol through the work and lives of six of America's finest writers: F. Scott Fitzgerald, Ernest Hemingway, Tennessee Williams, John Berryman, John Cheever, and Raymond Carver. All six of these men were alcoholics, and the subject of drinking surfaces in some of their finest work, from Cat on a Hot Tin Roof to A Moveable Feast.

Brilliantly funny, frank, and shattering, this is the bittersweet memoir by Peter McGough of his life with artist David McDermott. Set in New York’s Lower East Side of the 1980s and mid-1990s, it is also a devastatingly candid look at the extreme naiveté and dysfunction that would destroy both their lives.

"Congratulations on the resurrection of your life", a colleague wrote to Emily Rapp Black when she announced the birth of her second child. The line made Rapp Black pause. Her first child, a boy named Ronan, had died from Tay-Sachs disease before he turned three years old, an experience she wrote about in her second book, The Still Point of the Turning World. Since that time, her life had changed utterly.

Tom Scharpling is good at being funny, which is a miracle, considering what he’s survived. Like hitting a deer and narrowly escaping with his life on the night of the 2016 election. But that’s nothing compared to the struggles he had earlier in his life. It Never Ends is his memoir of a life writing comedy amidst a lifelong struggle with mental illness, a story he has never told before. It’s the heartbreaking account of his intense coming-of-age, and the lengths he’s undertaken to pull away from the brink of self-destruction.

Laura Trujillo had been close to her mother for most of her adult life, raising her four children within a few miles of their beloved grandmother’s Phoenix home. But just three months after moving her young family to Cincinnati for a new job, Laura receives shocking news: Her mother had taken her own life—by jumping off a ledge into the Grand Canyon, a place Laura knew her mother had always loved.

From National Book Award finalist Megan K. Stack, a stunning memoir of raising her children abroad with the help of Chinese and Indian women who are also working mothers....

I Am Yours is the story of Reema Zaman's unwavering fight to protect and free her voice from those who have sought to silence her. From Bangladesh to Thailand to New York to Oregon, through gorgeous prose as beautiful as it is biting, poetic as it is political, and healing as it is haunting, Zaman explores the many difficulties, dangers, and, ultimately, the necessity for all women, all people, to own and use their voices.

Late one night, while Rebecca Fogg was alone in her apartment, her hand was partially amputated in an explosion. Quick thinking saved her life, but the journey to recovery would be a slow one. As the doctors rebuilt her hand, Rebecca (who also survived 9/11) began rebuilding her sense of self by studying the physical and psychological process of recovery.

The unbelievable true story of Harrison Post - the enigmatic lover of one of the richest men in 1920s Hollywood - and the battle for a family fortune.

Born and raised in a tight-knit Orthodox Jewish family, Tova Mirvis committed herself to observing the rules and rituals prescribed by this way of life. After all, to observe was to be accepted and to be accepted was to be loved. She married a man from within the fold and quickly began a family. But over the years, her doubts became noisier than her faith, and at age 40 she could no longer breathe in what had become a suffocating existence.

Do you ever wonder how you woke up one day with all the responsibilities of a grown-up who secretly enjoys buying groceries in bulk, can no longer recognize the tween celebrities on the magazines at checkout, but is still surprised when a Starbucks barista calls you “ma’am” - because your inside self is frozen in time to about 20 years ago? So does Lisa-Jo Baker.