A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

Causal Inference provides a brief and nontechnical introduction to randomized experiments, propensity scores, natural experiments, instrumental variables, sensitivity analysis, and quasi-experimental devices. Ideas are illustrated with examples from medicine, epidemiology, economics and business, the social sciences, and public policy.

Since it was first published in 2005, Ray Kurzweil's The Singularity Is Near and its vision of the future have been influential in spawning a worldwide movement with millions of followers, hundreds of books, major films, and thousands of articles. During the succeeding decade, many of Kurzweil's predictions about technological advancements have been borne out, and their viability has become familiar to the public through such now commonplace concepts. In this entirely new book Ray Kurzweil brings a fresh perspective to advances in the singularity.

We are entering a new technological age in which artificial intelligence and immersive media will transform society at all levels, mediating our lives by altering what we see, hear, and experience. If managed well, this could unleash a new age of abundance. If managed poorly, this technological revolution could easily go astray, compromising our privacy, autonomy, agency, and humanity. Two industry veterans provide a data-driven debate on whether the new world we're creating will be a technological utopia or an AI-powered dystopia and give guidance on how to aim for the best future we can.

Why have so many Americans turned against democracy? In this deeply reported book, Katherine Stewart takes us to conferences of conspiracy-mongers, backroom strategy gatherings, and services at extremist churches, and profiles the people who want to tear it all down.

Why has war been such a consistent presence throughout the human past? A leading historian explains, drawing on rich examples and keen insight. Richard Overy is not the first scholar to take up the title question. In 1931, at the request of the League of Nations, Albert Einstein asked Sigmund Freud to collaborate on a short work examining whether there was "a way of delivering mankind from the menace of war." Published the next year as a pamphlet entitled Why War?, it conveyed Freud's conclusion that the "death drive" made any deliverance impossible.

We are living through a revolution in machine learning-powered AI that shows no signs of slowing down. This technology is based on relatively simple mathematical ideas, some of which go back centuries, including linear algebra and calculus, the stuff of seventeenth- and eighteenth-century mathematics. It took the birth and advancement of computer science and the kindling of 1990s computer chips designed for video games to ignite the explosion of AI that we see today. In this enlightening book, Anil Ananthaswamy explains the fundamental math behind machine learning.

Within the next five years, Jeremy Kahn predicts, AI will disrupt almost every industry and enterprise, with vastly increased efficiency and productivity. It will restructure the workforce, making AI copilots a must for every knowledge worker. It will compel us to reimagine how we make art, compose music, and write and publish books. The potential of generative AI to extend our skills, talents, and creativity as humans is undeniably exciting and promising. But while this new technology has a bright future, it also casts a dark and fearful shadow.

The knowledge of death is so terrifying that we live most of our lives in denial of it. One of the most difficult moments of childhood must be when each of us first realizes that not only we but all our loved ones will die—and there is nothing we can do about it. Or at least, there hasn’t been. Today, we are living through a revolution in biology. Giant strides are being made in understanding why we age—and why some species live longer than others. Could we eventually cheat disease and death and live for a very long time, possibly many times our current lifespan?

Hal Brands argues that a better understanding of Eurasia's strategic geography can illuminate the contours of rivalry and conflict in today's world. The Eurasian Century explains how revolutions in technology and warfare, and the rise of toxic ideologies of conquest, made Eurasia the center of twentieth-century geopolitics—with pressing implications for the struggles that will define the twenty-first.

Artificial intelligence and cybersecurity veteran Justin Hutchens delivers an incisive and penetrating look at how contemporary and future AI can and will be weaponized for malicious and adversarial purposes. In the book, you will explore the history of social engineering and social robotics, the psychology of deception, considerations of machine sentience and consciousness, and the history of how technology has been weaponized in the past.

What is life? In this penetrating and wide-ranging book, world-renowned physicist and science communicator Paul Davies searches for answers in a field so new and fast-moving that it lacks a name; it is a domain where biology, computing, logic, chemistry, quantum physics, and nanotechnology intersect.

Confused about AI and worried about what it means for your future and the future of the world? You’re not alone. AI is everywhere—and few things are surrounded by so much hype, misinformation, and misunderstanding. In AI Snake Oil, computer scientists Arvind Narayanan and Sayash Kapoor cut through the confusion to give you an essential understanding of how AI works, why it often doesn’t, where it might be useful or harmful, and when you should suspect that companies are using AI hype to sell AI snake oil—products that don’t work, and probably never will.

As it absorbs data, gains agency, and intermediates between humans and reality, AI will help us to address enormous crises, from climate change to geopolitical conflicts to income inequality. It might well solve some of the greatest mysteries of our universe, revolutionize fields as diverse as medicine and architecture, and elevate the human spirit to unimaginable heights. But it will also pose challenges on a scale and of an intensity that we have never seen.

Nvidia is the darling of the age of artificial intelligence: the company’s chips are powering the generative-AI revolution, and demand is insatiable. For all the current interest and attention, however, Nvidia is not of our time. Founded more than three decades ago in a Denny’s in East San Jose, for years it was known primarily in the then-niche world of computer gaming. In fact, the company’s leather-jacketed leader, Jensen Huang, is the longest-serving CEO in an industry marked by near constant turmoil and failure.

From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic engineering is shaking the core foundations of our lives-sex, war, love, and death. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.

A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

Bostrom’s previous book, Superintelligence: Paths, Dangers, Strategies (OUP, 2014) sparked a global conversation on AI that continues to this day. That book, which became a surprise New York Times bestseller, focused on what might happen if AI development goes wrong. But what if things go right? Suppose we develop superintelligence safely and ethically, and that we make good use of the almost magical powers this technology would unlock.

Within the next five years, Jeremy Kahn predicts, AI will disrupt almost every industry and enterprise, with vastly increased efficiency and productivity. It will restructure the workforce, making AI copilots a must for every knowledge worker. It will compel us to reimagine how we make art, compose music, and write and publish books. The potential of generative AI to extend our skills, talents, and creativity as humans is undeniably exciting and promising. But while this new technology has a bright future, it also casts a dark and fearful shadow.

What is life? This is among the most difficult open problems in science, right up there with the nature of consciousness and the existence of matter. All the definitions we have fall short. None help us understand how life originates or the full range of possibilities for what life on other planets might look like. In Life as No One Knows It, physicist and astrobiologist Sara Imari Walker argues that solving the origin of life requires radical new thinking and an experimentally testable theory for what life is.

Sociogenomics brings together advances in molecular genetics and traditional social and behavioral science. The key tool is the polygenic index, which allows us to analyze DNA to measure a child's genetic potential. Today, we can estimate a child's adult height, how far they will go in school, and their weight as an adult—all from a cheek swab, finger prick, or vial of saliva. Dalton Conley and other researchers are using this new science to shed light on the ways in which genes shape our world, influencing how each person both creates and responds to the environment around them.

For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.

How does a neural network become a brain? While neurobiologists investigate how nature accomplishes this feat, computer scientists interested in AI strive to achieve this through technology. The Self-Assembling Brain tells the stories of both fields, exploring the historical and modern approaches taken by the scientists pursuing answers to the quandary: What information is necessary to make an intelligent neural network? As Peter Robin Hiesinger argues, "the information problem" underlies both fields.

We are living through a revolution in machine learning-powered AI that shows no signs of slowing down. This technology is based on relatively simple mathematical ideas, some of which go back centuries, including linear algebra and calculus, the stuff of seventeenth- and eighteenth-century mathematics. It took the birth and advancement of computer science and the kindling of 1990s computer chips designed for video games to ignite the explosion of AI that we see today. In this enlightening book, Anil Ananthaswamy explains the fundamental math behind machine learning.

Since it was first published in 2005, Ray Kurzweil's The Singularity Is Near and its vision of the future have been influential in spawning a worldwide movement with millions of followers, hundreds of books, major films, and thousands of articles. During the succeeding decade, many of Kurzweil's predictions about technological advancements have been borne out, and their viability has become familiar to the public through such now commonplace concepts. In this entirely new book Ray Kurzweil brings a fresh perspective to advances in the singularity.

Synthetic biology promises to reveal how life is created and how it can be re-created, enabling scientists to rewrite the rules of our reality. It could help us, for example, heal without prescription medications, grow meat without harvesting animals, or confront our looming climate catastrophe. Synthetic biology will determine the ways in which we conceive future generations and how we define family, how we identify disease and treat aging, where we make our homes, and how we nourish ourselves.

Today's "machine-learning" systems, trained by data, are so effective that we've invited them to see and hear for us - and to make decisions on our behalf. But alarm bells are ringing. Systems cull résumés until, years later, we discover that they have inherent gender biases. Algorithms decide bail and parole - and appear to assess black and white defendants differently. We can no longer assume that our mortgage application, or even our medical tests, will be seen by human eyes. And autonomous vehicles on our streets can injure or kill.

Arguably the most significant scientific discovery of the new century, the mapping of the 23 pairs of chromosomes that make up the human genome raises almost as many questions as it answers - questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Matt Ridley here probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome.

In November 2022, a webpage was posted online with a simple text box. It was ChatGPT, and was unlike any app people had used before. It was more human than a customer service agent, more convenient than a Google search. Behind the scenes, battles for control and prestige between the world’s two leading AI firms, OpenAI and DeepMind, who now steers Google's AI efforts, has remained elusive—until now.

In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading. Coming at a time of economic recession and declining technological competitiveness in the United States, the event ignited a period of speculative frenzy over biotechnology.