A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

Causal Inference provides a brief and nontechnical introduction to randomized experiments, propensity scores, natural experiments, instrumental variables, sensitivity analysis, and quasi-experimental devices. Ideas are illustrated with examples from medicine, epidemiology, economics and business, the social sciences, and public policy.

Since it was first published in 2005, Ray Kurzweil's The Singularity Is Near and its vision of the future have been influential in spawning a worldwide movement with millions of followers, hundreds of books, major films, and thousands of articles. During the succeeding decade, many of Kurzweil's predictions about technological advancements have been borne out, and their viability has become familiar to the public through such now commonplace concepts. In this entirely new book Ray Kurzweil brings a fresh perspective to advances in the singularity.

We are living through a revolution in machine learning-powered AI that shows no signs of slowing down. This technology is based on relatively simple mathematical ideas, some of which go back centuries, including linear algebra and calculus, the stuff of seventeenth- and eighteenth-century mathematics. It took the birth and advancement of computer science and the kindling of 1990s computer chips designed for video games to ignite the explosion of AI that we see today. In this enlightening book, Anil Ananthaswamy explains the fundamental math behind machine learning.

Why has war been such a consistent presence throughout the human past? A leading historian explains, drawing on rich examples and keen insight. Richard Overy is not the first scholar to take up the title question. In 1931, at the request of the League of Nations, Albert Einstein asked Sigmund Freud to collaborate on a short work examining whether there was "a way of delivering mankind from the menace of war." Published the next year as a pamphlet entitled Why War?, it conveyed Freud's conclusion that the "death drive" made any deliverance impossible.

We are entering a new technological age in which artificial intelligence and immersive media will transform society at all levels, mediating our lives by altering what we see, hear, and experience. If managed well, this could unleash a new age of abundance. If managed poorly, this technological revolution could easily go astray, compromising our privacy, autonomy, agency, and humanity. Two industry veterans provide a data-driven debate on whether the new world we're creating will be a technological utopia or an AI-powered dystopia and give guidance on how to aim for the best future we can.

Dr. Marty Makary is co-developer of the life-saving checklist outlined in Atul Gawande's best-selling The Checklist Manifesto. As a busy surgeon who has worked in many of the best hospitals in the nation, he can testify to the amazing power of modern medicine to cure. But he's also been a witness to a medical culture that routinely leaves surgical sponges inside patients, amputates the wrong limbs, and overdoses children because of sloppy handwriting. Over the last 10 years, neither error rates nor costs have come down, despite scientific progress.

Within the next five years, Jeremy Kahn predicts, AI will disrupt almost every industry and enterprise, with vastly increased efficiency and productivity. It will restructure the workforce, making AI copilots a must for every knowledge worker. It will compel us to reimagine how we make art, compose music, and write and publish books. The potential of generative AI to extend our skills, talents, and creativity as humans is undeniably exciting and promising. But while this new technology has a bright future, it also casts a dark and fearful shadow.

The knowledge of death is so terrifying that we live most of our lives in denial of it. One of the most difficult moments of childhood must be when each of us first realizes that not only we but all our loved ones will die—and there is nothing we can do about it. Or at least, there hasn’t been. Today, we are living through a revolution in biology. Giant strides are being made in understanding why we age—and why some species live longer than others. Could we eventually cheat disease and death and live for a very long time, possibly many times our current lifespan?

Something new entered our world in November 2022—the first general purpose AI that could pass for a human and do the kinds of creative, innovative work that only humans could do previously. Wharton professor Ethan Mollick immediately understood what ChatGPT meant: after millions of years on our own, humans had developed a kind of co-intelligence that could augment, or even replace, human thinking. Through his writing, speaking, and teaching, Mollick has become one of the most prominent and provocative explainers of AI.

Artificial intelligence and cybersecurity veteran Justin Hutchens delivers an incisive and penetrating look at how contemporary and future AI can and will be weaponized for malicious and adversarial purposes. In the book, you will explore the history of social engineering and social robotics, the psychology of deception, considerations of machine sentience and consciousness, and the history of how technology has been weaponized in the past.

As it absorbs data, gains agency, and intermediates between humans and reality, AI will help us to address enormous crises, from climate change to geopolitical conflicts to income inequality. It might well solve some of the greatest mysteries of our universe, revolutionize fields as diverse as medicine and architecture, and elevate the human spirit to unimaginable heights. But it will also pose challenges on a scale and of an intensity that we have never seen.

Think creatively like a human. Analyze and solve problems efficiently like a computer. Our everyday lives are filled with inefficient and ineffective decisions and solutions. Being overwhelmed by the magnitude of our problems makes it hard to think clearly. We procrastinate and overthink. Our thoughts are tainted with biases. If only there was a way to simplify our decision-making and problem-solving process and get satisfying, consistent results! The good news is, there is! Apply computer algorithms to your everyday problems.

In How to Create a Mind, Ray Kurzweil presents a provocative exploration of the most important project in human-machine civilization: reverse-engineering the brain to understand precisely how it works and using that knowledge to create even more intelligent machines. Kurzweil discusses how the brain functions, how the mind emerges, brain-computer interfaces, and the implications of vastly increasing the powers of our intelligence to address the world’s problems.

In the popular imagination, superhuman artificial intelligence is an approaching tidal wave that threatens not just jobs and human relationships, but civilization itself. Conflict between humans and machines is seen as inevitable and its outcome all too predictable. In this groundbreaking audiobook, distinguished AI researcher Stuart Russell argues that this scenario can be avoided, but only if we rethink AI from the ground up. Russell begins by exploring the idea of intelligence in humans and in machines.

From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic engineering is shaking the core foundations of our lives-sex, war, love, and death. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.

A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

We are entering a new technological age in which artificial intelligence and immersive media will transform society at all levels, mediating our lives by altering what we see, hear, and experience. If managed well, this could unleash a new age of abundance. If managed poorly, this technological revolution could easily go astray, compromising our privacy, autonomy, agency, and humanity. Two industry veterans provide a data-driven debate on whether the new world we're creating will be a technological utopia or an AI-powered dystopia and give guidance on how to aim for the best future we can.

Dreaming is one of the most underappreciated functions of the human brain, yet our very survival as a species depends on it. In This Is Why You Dream, dual-trained neuroscientist and neurosurgeon Dr. Rahul Jandial explores the landscape of our subconscious, tracing the latest cutting-edge dream research and brain science to show why humans have retained the ability to dream across millennia, and how we can now harness its wondrous powers to improve our sleeping and waking lives.

Written by an author with plenty of experience holding a scalpel, Dr. David Schneider's in-depth biography is an encompassing history of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing implant revolution of the 20th century.

What is life? This is among the most difficult open problems in science, right up there with the nature of consciousness and the existence of matter. All the definitions we have fall short. None help us understand how life originates or the full range of possibilities for what life on other planets might look like. In Life as No One Knows It, physicist and astrobiologist Sara Imari Walker argues that solving the origin of life requires radical new thinking and an experimentally testable theory for what life is.

These Are the Plunderers traces the thirty-year history of corporate takeovers in America and private equity’s increasing dominance. Morgenson and Rosner investigate some of the biggest names in private equity, exposing how they buy companies, load them with debt, and then bleed them of assets and profits. All while prosecutors and regulators stand idly by.

For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.

Within the next five years, Jeremy Kahn predicts, AI will disrupt almost every industry and enterprise, with vastly increased efficiency and productivity. It will restructure the workforce, making AI copilots a must for every knowledge worker. It will compel us to reimagine how we make art, compose music, and write and publish books. The potential of generative AI to extend our skills, talents, and creativity as humans is undeniably exciting and promising. But while this new technology has a bright future, it also casts a dark and fearful shadow.

How does a neural network become a brain? While neurobiologists investigate how nature accomplishes this feat, computer scientists interested in AI strive to achieve this through technology. The Self-Assembling Brain tells the stories of both fields, exploring the historical and modern approaches taken by the scientists pursuing answers to the quandary: What information is necessary to make an intelligent neural network? As Peter Robin Hiesinger argues, "the information problem" underlies both fields.

Sociogenomics brings together advances in molecular genetics and traditional social and behavioral science. The key tool is the polygenic index, which allows us to analyze DNA to measure a child's genetic potential. Today, we can estimate a child's adult height, how far they will go in school, and their weight as an adult—all from a cheek swab, finger prick, or vial of saliva. Dalton Conley and other researchers are using this new science to shed light on the ways in which genes shape our world, influencing how each person both creates and responds to the environment around them.

Medicine has become inhuman, to disastrous effect. The doctor-patient relationship - the heart of medicine - is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality.

Equal parts Sapiens, Behave, and Superintelligence, but wholly original in scope, A Brief History of Intelligence offers a paradigm shift for how we understand neuroscience and AI. Artificial intelligence entrepreneur Max Bennett chronicles the five “breakthroughs” in the evolution of human intelligence and reveals what brains of the past can tell us about the AI of tomorrow.

We are living through a revolution in machine learning-powered AI that shows no signs of slowing down. This technology is based on relatively simple mathematical ideas, some of which go back centuries, including linear algebra and calculus, the stuff of seventeenth- and eighteenth-century mathematics. It took the birth and advancement of computer science and the kindling of 1990s computer chips designed for video games to ignite the explosion of AI that we see today. In this enlightening book, Anil Ananthaswamy explains the fundamental math behind machine learning.

Since it was first published in 2005, Ray Kurzweil's The Singularity Is Near and its vision of the future have been influential in spawning a worldwide movement with millions of followers, hundreds of books, major films, and thousands of articles. During the succeeding decade, many of Kurzweil's predictions about technological advancements have been borne out, and their viability has become familiar to the public through such now commonplace concepts. In this entirely new book Ray Kurzweil brings a fresh perspective to advances in the singularity.