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The Catalyst
RNA and the Quest to Unlock Life's Deepest Secrets
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Narrated by:
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Joshua Saxon
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By:
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Thomas R. Cech
About this listen
For over half a century, DNA has dominated science and the popular imagination as the "secret of life." But over the last several decades, a quiet revolution has taken place. In a series of breathtaking discoveries, the biochemist Thomas R. Cech and a diverse cast of brilliant scientists have revealed that RNA-long overlooked as the passive servant of DNA-sits at the center of biology's greatest mysteries: How did life begin? What makes us human? Why do we get sick and grow old? In The Catalyst, Cech finally brings together years of research to demonstrate that RNA is the true key to understanding life on Earth, from its very origins to our future in the twenty-first century.
A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health. We learn how RNA may have jump-started life itself, and how, at the same time, it can cut our individual lives short through viral diseases and cancer. We see how RNA is implicated in the aging process and explore the darker depths of the supposed fountain of youth, telomerase. And we catch a thrilling glimpse into how RNA-powered therapies may enable us to improve and even extend life beyond nature's current limits.
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Welcome to the Universe is a personal guided tour of the cosmos by three of today's leading astrophysicists. Inspired by the enormously popular introductory astronomy course that Neil deGrasse Tyson, Michael A. Strauss, and J. Richard Gott taught together at Princeton, this book covers it all - from planets, stars, and galaxies to black holes, wormholes, and time travel.
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All About What We Know About the Universe - ALL
- By J.B. on 02-17-17
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Inspired
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How do today's most successful tech companies - Amazon, Google, Facebook, Netflix, Tesla - design, develop, and deploy the products that have earned the love of literally billions of people around the world? Perhaps surprisingly, they do it very differently from the vast majority of tech companies. In Inspired, technology product management thought leader Marty Cagan provides listeners with a master class in how to structure and staff a vibrant and successful product organization and how to discover and deliver technology products that your customers will love.
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Great book, terrible audio wanted to ask a refund
- By Srikanth Ramanujam on 11-15-18
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- By: Thomas Hager
- Narrated by: Angelo Di Loreto
- Length: 8 hrs and 39 mins
- Unabridged
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Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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Engrossing to physicians & lay persons alike
- By C. White on 03-08-19
By: Thomas Hager
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The Quantum Universe
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- Narrated by: Samuel West
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In The Quantum Universe, Brian Cox and Jeff Forshaw approach the world of quantum mechanics in the same way they did in Why Does E=mc2? and make fundamental scientific principles accessible - and fascinating - to everyone.The subatomic realm has a reputation for weirdness, spawning any number of profound misunderstandings, journeys into Eastern mysticism, and woolly pronouncements on the interconnectedness of all things. Cox and Forshaw's contention? There is no need for quantum mechanics to be viewed this way.
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Not suitable as an audio book
- By SPN on 03-29-22
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Ranger Confidential
- Living, Working, and Dying in the National Parks
- By: Andrea Lankford
- Narrated by: Julia Motyka
- Length: 9 hrs and 28 mins
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The real stories behind the scenery of America’s national parks. For 12 years, Andrea Lankford lived in the biggest, most impressive national parks in the world, working a job she loved. She chaperoned baby sea turtles on their journey to sea. She pursued bad guys on her galloping patrol horse. She jumped into rescue helicopters bound for the heart of the Grand Canyon. She won arguments with bears. She slept with a few too many rattlesnakes. Hell yeah, it was the best job in the world! Fortunately, Andrea survived it.
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Depressing from Cover to Cover
- By Drew (@drewsant) on 04-13-15
By: Andrea Lankford
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What listeners say about The Catalyst
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Trebla
- 08-23-24
Among the best at telling the story of science
As a biology major I was aware of much that Cech covers, but with the addition of much I did not know existed about RNA. Perhaps the best part is his descriptions of the visits, talks, papers, friends that actually drive basic science- it is a team sport.
The down mark is for the speaker who just murdered too many well-known bio words- very distracting.
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- Auinash Kalsotra
- 09-16-24
Captivating
Highly accessible to non experts. A wonderful weekend read. Will recommend to high school students and teachers
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- Amazon Customer
- 08-14-24
Disappointing
Given the author’s qualifications, I was expecting something way less superficial. It’s also full of dozens of unneeded and unilluminating analogies that largely serve only as a distraction. Also annoying was the increasingly common in audiobooks disclaimer that the narration refers to illustrations/charts that are found only in the paper/e-book versions of this book, instead of actually providing a PDF of those to refer to.
The narration also was disappointing. Among other things, the narrator could’ve spent a few minutes learning how to pronounce the words he was supposed to read. Or someone who actually understood the subject matter should’ve proof-listened to the narration and insisted on corrections. And it’s not just technical/biological terms that he mispronounces. He even mispronounces La Jolla (California), as “la-HOLE-a.” A truly slipshod effort.
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- Anonymous User
- 08-22-24
Disappointing reader!!
The reading is more robotic and most of the information is needless— wish it was more direct and accurate.
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- Mom
- 07-31-24
a discredit to women scientists everywhere
I was so excited to read this book. I pre-ordered the hard copy and the audible version. Midway through chapter one I immediately stopped. I requested a refund for both books and WILL NOT read or recommend it to anyone. Thomas Cech has done a great dishonor to women scientists everywhere. He proudly discussed DNA, Watson and Crick, Kings College with NO mention of Rosalind Franklin, further proving that old, white male scientists go out of their way to discredit women in science.
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1 person found this helpful