The Good Virus
The Amazing Story and Forgotten Promise of the Phage
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Narrated by:
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Ben Deery
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By:
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Tom Ireland
About this listen
How a mysterious, super-powerful—yet long-neglected—microbe rules our world and can rescue our health in the age of antibiotic resistance.
At every moment, within our bodies and all around us, trillions of microscopic combatants are waging a war that shapes our health and life on Earth. Countless times per second, viruses known as phages attack and destroy bacteria while leaving all other life forms, including us, unscathed. Vastly outnumbering the viruses that do us harm, phages power ecosystems, drive evolutionary innovation, and harbor a remarkable capacity to heal life-threatening infections when conventional antibiotics fail. Yet most of us have never heard of them, thinking of viruses only as enemies to be feared. The Good Virus prompts us to reconsider, and to discover, how these viruses could save countless lives if we can learn to harness their extraordinary abilities.
Taking us inside the ongoing quest to use phages’ powers for good, Tom Ireland introduces us to the brilliant, often eccentric, scientists who have fought to realize phages’ potential in the face of doubt and political intrigue. We meet the renegade French-Canadian scientist who discovered phages and pioneered their use as medicine over a century ago, leading them to be hailed as the world’s first genuine antibiotic years before penicillin. We learn why, in some pockets of the former Soviet Union, drinking a vial of phages remains as common as taking an over-the-counter drug. We follow the intrepid scientists and doctors now racing to make “phage therapy” work worldwide as the threat of antibiotic-resistant bacteria grows ever more urgent—even as other researchers uncover how phages bolster our everyday immunity, help generate the oxygen we breathe, and furnish the origins for breakthrough technologies like CRISPR.
Unveiling the hidden rulers of the microbial world and celebrating the surprising power of viruses to heal, not harm, The Good Virus forever changes how we see nature’s most maligned life forms.
©2023 Tom Ireland (P)2023 Random House AudioListeners also enjoyed...
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Critic reviews
"A colorful redemption story for the oft-neglected yet incredibly abundant phage. . . . Ireland, an award-winning science journalist, approaches the subject of his first book with curiosity and passion, delivering a deft narrative that is rich and approachable. (Alex Johnson, The New York Times Book Review)
"As engaging as it is expansive, The Good Virus describes the distinctive biology and murky history of bacteriophage (generally shortened to ‘phage’), a form of life that is remarkably abundant yet obscure enough to have been termed the ‘dark matter of biology.'" (David A. Shaywitz, Wall Street Journal)
A masterful blend of jaw-dropping science and absorbing storytelling. . . . This book reminds us of the missed opportunities we simply cannot afford to miss again. (George McGavin, BBC and Discovery Channel presenter)
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Happy Accidents is a fascinating, entertaining, and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the 20th century. What do penicillin, chemotherapy drugs, X-rays, Valium, the Pap smear, and Viagra have in common? They were each discovered accidentally, stumbled upon in the search for something else. In discussing medical breakthroughs, Dr. Morton Meyers makes a cogent, highly engaging argument for a more creative, rather than purely linear, approach to science. And it may just save our lives!
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Don't waste your money!
- By Amazon Customer on 03-20-16
By: Morton A. Meyers
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The Emperor of All Maladies
- A Biography of Cancer
- By: Siddhartha Mukherjee
- Narrated by: Fred Sanders
- Length: 22 hrs and 18 mins
- Unabridged
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Performance
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The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".
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Incredible
- By S.R.E. on 03-02-16
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A Shot to Save the World
- The Inside Story of the Life-or-Death Race for a COVID-19 Vaccine
- By: Gregory Zuckerman
- Narrated by: Jack Armstrong
- Length: 12 hrs and 6 mins
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Story
Few were ready when a mysterious respiratory illness emerged in Wuhan, China, in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization.
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Wow! Do not miss this one.
- By Jacob on 11-18-21
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- By: Daniel M. Davis
- Narrated by: Christopher Grove
- Length: 7 hrs and 48 mins
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Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
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Ravenous
- Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection
- By: Sam Apple
- Narrated by: Mark Bramhall
- Length: 12 hrs and 58 mins
- Unabridged
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The Nobel laureate Otto Warburg was widely regarded in his day as one of the most important biochemists of the 20th century, a man whose research was integral to humanity’s understanding of cancer. He was also among the most despised figures in Nazi Germany. As a Jewish homosexual living openly with his male partner, Warburg represented all that the Third Reich abhorred. Yet Hitler and his top advisors dreaded cancer, and protected Warburg in the hope that he could cure it.
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Highly recommended, a must read.
- By Joerg on 06-10-21
By: Sam Apple
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Influenza
- The Hundred-Year Hunt to Cure the 1918 Spanish Flu Pandemic
- By: Dr. Jeremy Brown
- Narrated by: Holter Graham
- Length: 6 hrs and 28 mins
- Unabridged
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Overall
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Performance
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On the 100th anniversary of the devastating pandemic of 1918, Jeremy Brown, a veteran ER doctor, explores the troubling, terrifying, and complex history of the flu virus, from the origins of the Great Flu that killed millions, to vexing questions such as: are we prepared for the next epidemic, should you get a flu shot, and how close are we to finding a cure?
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Important read
- By Kathryn C. on 12-21-18
By: Dr. Jeremy Brown
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Plagues, Pandemics and Viruses
- From the Plague of Athens to COVID-19
- By: Heather E. Quinlan
- Narrated by: Samara Naeymi
- Length: 14 hrs and 28 mins
- Unabridged
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It can come in waves - like tidal waves. It changes societies. It disrupts life. It ends lives. As far back as 3000 B.C.E. (the Bronze Age), plagues have stricken mankind. COVID-19 is just the latest example, but history shows that life continues. It shows that knowledge and social cooperation can save lives. Viruses are neither alive nor dead and are the closest thing we have to zombies. Their only known function is to replicate themselves, which can have devastating consequences on their hosts.
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Somewhat elemental
- By Bertha Watkins on 10-23-21
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Plague of Corruption
- Restoring Faith in the Promise of Science
- By: Dr. Judy Mikovits, Kent Heckenlively, Robert F. Kennedy Jr.
- Narrated by: Mariel Hemingway
- Length: 10 hrs and 10 mins
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Performance
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Dr. Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys' club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried.
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If only most of the public knew these facts
- By David Getoff, CCN on 06-18-20
By: Dr. Judy Mikovits, and others
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The Cancer Chronicles
- Unlocking Medicine's Deepest Mystery
- By: George Johnson
- Narrated by: Arthur Morey
- Length: 8 hrs and 19 mins
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When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.
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A quick read - hard to put down
- By Digital Dilema on 09-06-13
By: George Johnson
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Evolving Ourselves
- How Unnatural Selection and Nonrandom Mutation are Changing Life on Earth
- By: Juan Enriquez, Steve Gullans
- Narrated by: Rob Shapiro
- Length: 10 hrs and 50 mins
- Unabridged
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Overall
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Why are conditions like autism, asthma, obesity, and allergies exploding at unprecedented rates? Why are we living longer, getting smarter, having far fewer kids? If Darwin were alive today, how would he explain this new world?
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fascinating ideas and science
- By Joel on 07-04-15
By: Juan Enriquez, and others
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Denialism
- How Irrational Thinking Hinders Scientific Progress, Harms the Planet, and Threatens Our Lives
- By: Michael Specter
- Narrated by: Richard Poe
- Length: 8 hrs and 33 mins
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New Yorker staff writer Michael Specter has twice won the Global Health Council’s Excellence in Media Award, as well as the Science Journalism Award from the American Association for the Advancement of Science. In Denialism, he fervently argues that people are turning away from new technologies and engaging in a kind of magical thinking that is hindering scientific progress.
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A compelling read
- By S on 05-17-11
By: Michael Specter
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Missing Microbes
- How the Overuse of Antibiotics Is Fueling Our Modern Plagues
- By: Martin J. Blaser
- Narrated by: Patrick Lawlor
- Length: 8 hrs and 43 mins
- Unabridged
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Performance
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Story
In Missing Microbes, Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now this invisible eden is being irrevocably damaged by some of our most revered medical advances-antibiotics-threatening the extinction of our irreplaceable microbes with terrible health consequences.
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Very enlightening and information well supported
- By James on 05-03-15
By: Martin J. Blaser
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The Demon Under The Microscope
- By: Thomas Hager
- Narrated by: Stephen Hoye
- Length: 12 hrs and 14 mins
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The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic medication. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.
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Great Book!!!!!
- By Amazon Customer on 05-21-08
By: Thomas Hager
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Tomorrowland
- Our Journey From Science Fiction to Science Fact
- By: Steven Kotler
- Narrated by: Tom Parks
- Length: 8 hrs and 58 mins
- Unabridged
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Overall
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Performance
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Story
New York Times, Wired, Atlantic Monthly, Discover bestselling author Steven Kotler has written extensively about those pivotal moments when science fiction became science fact...and fundamentally reshaped the world. Now he gathers the best of his best, updated and expanded upon, to guide listeners on a mind-bending tour of the far frontier, and how these advances are radically transforming our lives.
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Covers a lot of different topics in many industries
- By ErnieA on 06-27-15
By: Steven Kotler
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Love letter to RNA
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It's a Wonderful Book
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In How the World Ran Out of Everything, award-winning journalist Peter S. Goodman reveals the fascinating innerworkings of our supply chain and the factors that have led to its constant, dangerous vulnerability. His reporting takes listeners deep into the elaborate system, showcasing the triumphs and struggles of the human players who operate it—from factories in Asia and an almond grower in Northern California, to a group of striking railroad workers in Texas, to a truck driver who Goodman accompanies across hundreds of miles of the Great Plains.
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Must Read!
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The Worlds I See
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Wired called Dr. Fei-Fei Li “one of a tiny group of scientists—a group perhaps small enough to fit around a kitchen table—who are responsible for AI’s recent remarkable advances.” Known to the world as the creator of ImageNet, a key catalyst of modern artificial intelligence, Dr. Li has spent more than two decades at the forefront of the field. But her career in science was improbable from the start. The Worlds I See is the moving memoir of a scientist coming of age as an immigrant in America who finds her calling at the forefront of the AI revolution.
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Excellent
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The Light Eaters
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The Light Eaters is a deep immersion into the drama of green life and the complexity of this wild and awe-inspiring world that challenges our very understanding of agency, consciousness, and intelligence. In looking closely, we see that plants, rather than imitate human intelligence, have perhaps formed a parallel system.
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Entertaining perhaps but not science.
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Lies I Taught in Medical School
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For the first time in history, chronic diseases like diabetes, hypertension, and obesity plague our population on a global scale. From a seasoned physician, this paradigm-shifting book comprehensively explains the linked cause of chronic diseases and exposes the misconceptions prevalent in modern medicine. In Lies I Taught in Medical School, Robert Lufkin, MD, explains that metabolic dysfunction is the common underlying cause of most chronic diseases that has been overlooked for decades, providing the tools needed to prevent and reverse them in ourselves.
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Bold new perspectives
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What listeners say about The Good Virus
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- Diego Gutiérrez
- 05-20-24
Great review on the history of bacteriophages
I loved the comprehensive review of the history on how these viruses were discovered and current efforts to study them as a potential treatment.
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- Amazon Customer
- 09-10-23
superb
loved all of it. great science. great narration. everyone should give it a listen. so informative.
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- Tally D Lykins
- 09-20-24
Excellent read
Very well researched and well written. Good, current information; nice to hear that more and more research and work in this area is being done.
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- ChHe
- 09-03-23
Excellent
Comprehensive review on all you need to know about Phages. Well written, never boring. It’s also easy in a way that it’s a joy to listen.
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- marti Livingston
- 01-21-24
The history is fascinating
Well researched and written, I enjoyed this book a great deal and have recommended it to all my friends.
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- Christopher
- 08-23-23
Good One
I remember a cursory overview of phages in my high school biology class but my textbook didn't say much more than they were weird, not much was known about them, and they didn't have much use.
Western medicine is just waking up to the potential use (or misuse) of these ever present little critters and there just isn't enough knowledge or experience to make a conclusion about further large scale pursuit of their possibilities.
I hope Tom Ireland will revisit this story in a decade and add a few more chapters of future discoveries to the end of this book.
Besides, anything that uses CRISPR, looks like a rock drill from a mining quarry, and invades living cells to explode them, has to be interesting. Maybe a SciFi novel in there somewhere?
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- M. T. P.
- 11-17-23
A very good introduction to phages
Having read “The Perfect Predator”, another good book on the subject, also with a T4 virus on the cover, this is a natural following. Is a very excellent writing on the history of bacteriophagology and their use in medicine. It is a “Who is Who”, until the date of publication and a result of an extensive research (the reference notes show it, on the print version). Being far from dry as a science book, it intermingles in the right amount: history, biology, technology, statistics, law, burocracy and even human drama, making a very enjoyable and informative reading.
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- Paul
- 10-11-23
No brainer
Perfect! Book is mind blowing. Everything that needs to be known about phages are in it
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- Suman Bhattacharyya
- 12-08-24
Riveting Subject Matter and Narrative
Loved how incredibly relevant this is today. Very well written and narrated. Could not stop listening
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- yoanna
- 05-03-24
Interesting book & terrible narration
For even a microbiologist like me, who studies antibiotics & phage therapies, this book is highly interesting & informative. The narrator on the other hand, is terrible. Can we please for once, get some who can properly pronounce the names of bacteria?!
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