In 1938, Donald Triplett of Forest, Mississippi, became the first child diagnosed with autism. Beginning with his family’s odyssey, In a Different Key tells the extraordinary story of this often misunderstood condition, from the civil rights battles waged by the families of those who have it to the fierce debates among scientists over how to define and treat it.

When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction, and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

When Randy Pausch, a computer science professor at Carnegie Mellon, was asked to give such a lecture, he didn't have to imagine it as his last, since he had recently been diagnosed with terminal cancer. But the lecture he gave - "Really Achieving Your Childhood Dreams" - wasn't about dying. It was about the importance of overcoming obstacles, of enabling the dreams of others, of seizing every moment (because "time is all you have... and you may find one day that you have less than you think").

An instant best seller that is poised to become a classic, Moonwalking with Einstein recounts Joshua Foer's yearlong quest to improve his memory under the tutelage of top "mental athletes". He draws on cutting-edge research, a surprising cultural history of remembering, and venerable tricks of the mentalist's trade to transform our understanding of human memory. From the United States Memory Championship to deep within the author's own mind, this is an electrifying work of journalism that reminds us that, in every way that matters, we are the sum of our memories.

Drawing on cutting-edge neurology and firsthand research gathered on journeys to nine of the world’s talent hotbeds - from the baseball fields of the Caribbean to a classical-music academy in upstate New York - Coyle identifies the three key elements that will allow you to develop your gifts and optimize your performance in sports, art, music, math, or just about anything.

In the New York Times bestseller Brain Rules, Dr. John Medina, a molecular biologist, shares his lifelong interest in how the brain sciences might influence the way we teach our children and the way we work. In each chapter, he describes a brain rule - what scientists know for sure about how our brains work - and then offers transformative ideas for our daily lives. Medina’s fascinating stories and infectious sense of humor breathe life into brain science.

With unequaled insight and brio, David Brooks, the New York Times columnist and bestselling author of Bobos in Paradise, has long explored and explained the way we live. Now, with the intellectual curiosity and emotional wisdom that make his columns among the most read in the nation, Brooks turns to the building blocks of human flourishing in a multilayered, profoundly illuminating work grounded in everyday life.

The beloved actor shares fascinating and powerful lessons from the science of communication and teaches listeners to improve the way they relate to others using improv games, storytelling, and their own innate mind-reading abilities. With his trademark humor and frankness, Alan Alda explains what makes the out-of-the-box techniques he developed after his years as the host of Scientific American Frontiers so effective.

To these seven narratives of neurological disorder Dr. Sacks brings the same humanity, poetic observation, and infectious sense of wonder that are apparent in his bestsellers Awakenings and The Man Who Mistook His Wife for a Hat. These men, women, and one extraordinary child emerge as brilliantly adaptive personalities, whose conditions have not so much debilitated them as ushered them into another reality.

From an early age, it is drilled into our heads: Restlessness, distraction, and ignorance are the enemies of success. We’re told that learning is all self-discipline, that we must confine ourselves to designated study areas, turn off the music, and maintain a strict ritual if we want to ace that test, memorize that presentation, or nail that piano recital. But what if almost everything we were told about learning is wrong?

In 1999, Clark Elliott suffered a concussion when his car was rear-ended. Overnight his life changed from that of a rising professor with a research career in artificial intelligence to a humbled man struggling to get through a single day. At times he couldn't walk across a room, or even name his five children. Doctors told him he would never fully recover. After eight years, the cognitive demands of his job, and of being a single parent, finally became more than he could manage.

What does a father do when hope is gone that his only son can ever lead anything close to a "normal" life? That's the question that haunted Dick Russell in the fall of 2011, when his son, Franklin, was 32. At the age of 17, Franklin had been diagnosed with schizophrenia. For years he spent time in and out of various hospitals, and even went through periods of adamantly denying that Dick was actually his father.

In You Have a Brain: A Teen's Guide to T.H.I.N.K. B.I.G., Dr. Carson unpacks the eight important parts of thinking big--talent, honesty, integrity, being nice, knowledge, books, in-depth learning, and God--and presents the stories of people who demonstrated those things in his life. By applying the idea of T.H.I.N.K. B.I.G. to your life, and by looking at those around you as well, you too can overcome obstacles and work toward achieving your dreams.

This enduring classic of educational thought offers teachers and parents deep, original insight into the nature of early learning. John Holt was the first to make clear that, for small children, "learning is as natural as breathing." In this delightful yet profound book, he looks at how we learn to talk, to read, to count, and to reason, and how we can nurture and encourage these natural abilities in our children.

In 1999, Clark Elliott suffered a concussion when his car was rear-ended. Overnight his life changed from that of a rising professor with a research career in artificial intelligence to a humbled man struggling to get through a single day. At times he couldn't walk across a room, or even name his five children. Doctors told him he would never fully recover. After eight years, the cognitive demands of his job, and of being a single parent, finally became more than he could manage.

We all learn at least one language as children. But what does it take to learn six languages...or seventy? In Babel No More, Michael Erard, "a monolingual with benefits," sets out on a quest to meet language superlearners and make sense of their mental powers. On the way he uncovers the secrets of historical figures like Italian cardinal Giuseppe Mezzofanti, who was said to speak seventy-two languages; Emil Krebs, a pugnacious German diplomat, who spoke sixty-eight languages; and Lomb Kat, a Hungarian who taught herself Russian by reading Russian romance novels.

Lauren Marks was 27 when an aneurysm ruptured in her brain and left her fighting for her life. She woke up in a hospital soon after with serious deficiencies to her reading, speaking, and writing abilities, and an unfamiliar diagnosis: aphasia. This would be shocking news for anyone, but Lauren was a voracious reader, an actress, director, dramaturg, and pursuing her PhD. At any other period of her life, this diagnosis would have been a devastating blow. But she woke up...different.

To these seven narratives of neurological disorder Dr. Sacks brings the same humanity, poetic observation, and infectious sense of wonder that are apparent in his bestsellers Awakenings and The Man Who Mistook His Wife for a Hat. These men, women, and one extraordinary child emerge as brilliantly adaptive personalities, whose conditions have not so much debilitated them as ushered them into another reality.

The noted research psychiatrist explores how life's disappointments and difficulties provide us with the lessons we need to become better, bigger, and more resilient human beings. Adversity is an irreducible fact of life. Although we can and should learn from all experiences, both positive and negative best-selling author Dr. Norman E. Rosenthal believes that adversity is by far the best teacher most of us will ever encounter.

A first-person account of Jim Tucker's experiences with a number of extraordinary children with memories of past lives, Return to Life focuses mostly on American cases, presenting each family's story and describing his investigation. His goal is to determine what happened-what the child has said, how the parents have reacted, whether the child's statements match the life of a particular deceased person, and whether the child could have learned such information through normal means.

In Crossing Over, John brings his listeners with him on the extraordinary journey that has been his life since his New York Times best seller One Last Time was published in 1998. In the style of his TV show and personal appearances (poignant, funny, and remarkably candid) John deals head-on with the controversial issues he has confronted on his voyage as a psychic medium. Listeners might be surprised to learn that it hasn't always been smooth sailing.

Expanding upon one of the most-read New York Times Magazine features of 2012, Smarter penetrates the hot new field of intelligence research to reveal what researchers call a revolution in human intellectual abilities. Shattering decades of dogma, scientists began publishing studies in 2008 showing that "fluid intelligence" - the ability to learn, solve novel problems, and get to the heart of things - can be increased through training. But is it all just hype?

One of the world's 50 living autistic savants is the first and only to tell his compelling and inspiring life story and explain how his incredible mind works. Worldwide, there are fewer than 50 living savants, those autistic individuals who can perform miraculous mental calculations or artistic feats. (Think Dustin Hoffman's character in Rain Man.) None of them has been able to discuss his or her thought processes, much less write a book. Until now.

Drawing on cutting-edge neurology and firsthand research gathered on journeys to nine of the world’s talent hotbeds - from the baseball fields of the Caribbean to a classical-music academy in upstate New York - Coyle identifies the three key elements that will allow you to develop your gifts and optimize your performance in sports, art, music, math, or just about anything.

This is the real-life story of Owen Suskind, the son of the Pulitzer Prize-winning journalist Ron Suskind and his wife, Cornelia. An autistic boy who couldn't speak for years, Owen memorized dozens of Disney movies, turned them into a language to express love and loss, kinship, brotherhood. The family was forced to become animated characters, communicating with him in Disney dialogue and song; until they all emerge, together, revealing how, in darkness, we all literally need stories to survive.

Groundbreaking anthropologist and memory champion Lynne Kelly reveals how we can use ancient and traditional mnemonic methods to enhance and expand our memory.

When Alex Stone was five years old, his father bought him a magic kit - a gift that would spark a lifelong love. Years later, while living in New York City, he discovered a vibrant underground magic scene exploding with creativity and innovation and populated by a fascinating cast of characters: from his gruff mentor, who holds court in the back of a rundown pizza shop, to one of the world's greatest card cheats, who also happens to be blind. Captivated, he plunged headlong into this mysterious world.

Every 69 seconds, someone is diagnosed with Alzheimer's disease. Of the top 10 killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can. The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer's, an inherited genetic mutation that causes the disease in 100 percent of cases, and has a 50 percent chance of being passed onto the next generation.

One day in 2002 the 50-year old body of former Pittsburgh Steeler and hall of famer Mike Webster was laid on a cold table in front of pathologist Dr. Bennet Omalu. Webster's body looked to Omalu like the body of a much older man, and the circumstances of his behavior prior to his death were clouded in mystery. But when Omalu cut into Webster's brain, it appeared to be normal. Something didn't add up.