
The Tangled Tree
A Radical New History of Life
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Narrated by:
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Jacques Roy
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By:
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David Quammen
About this listen
Nonpareil science writer David Quammen explains how recent discoveries in molecular biology can change our understanding of evolution and life’s history, with powerful implications for human health and even our own human nature.
In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field - the study of life’s diversity and relatedness at the molecular level - is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection - a type of HGT.
In The Tangled Tree David Quammen, “one of that rare breed of science journalists who blends exploration with a talent for synthesis and storytelling” (Nature), chronicles these discoveries through the lives of the researchers who made them - such as Carl Woese, the most important little-known biologist of the 20th century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.
“Quammen is no ordinary writer. He is simply astonishing, one of that rare class of writer gifted with verve, ingenuity, humor, guts, and great heart” (Elle). Now, in The Tangled Tree, he explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life - including where we humans fit upon it. Thanks to new technologies such as CRISPR, we now have the ability to alter even our genetic composition - through sideways insertions, as nature has long been doing. The Tangled Tree is a brilliant guide to our transformed understanding of evolution, of life’s history, and of our own human nature.
©2018 David Quammen (P)2018 Simon & SchusterListeners also enjoyed...
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- By A. Mandelin on 08-02-18
By: Edward O. Wilxon
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At the Edge of Uncertainty
- 11 Discoveries Taking Science by Surprise
- By: Michael Brooks
- Narrated by: Sean Runnette
- Length: 9 hrs and 12 mins
- Unabridged
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The atom, the big bang, DNA, natural selection - all are ideas that have revolutionized science; and all were dismissed out of hand when they first appeared. The surprises haven't stopped in recent years, and in At the Edge of Uncertainty, best-selling author Michael Brooks investigates the new wave of radical insights that are shaping the future of scientific discovery.
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All smoke, no fire
- By Kenton on 07-25-15
By: Michael Brooks
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Herding Hemingway's Cats
- Understanding How Our Genes Work
- By: Kat Arney
- Narrated by: Kat Arney
- Length: 8 hrs and 39 mins
- Unabridged
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The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work?
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A non-scientists misguided interpretation
- By AraSevera on 05-15-16
By: Kat Arney
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The Cosmic Serpent
- DNA and the Origins of Knowledge
- By: Jeremy Narby
- Narrated by: James Patrick Cronin
- Length: 4 hrs and 55 mins
- Unabridged
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This adventure in science and imagination, which the Medical Tribune said might herald "a Copernican revolution for the life sciences", leads the listener through unexplored jungles and uncharted aspects of mind to the heart of knowledge. In a first-person narrative of scientific discovery that opens new perspectives on biology, anthropology, and the limits of rationalism, The Cosmic Serpent reveals how startlingly different the world around us appears when we open our minds to it.
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Very Good Religious Text
- By Blair K. Hartman on 08-09-17
By: Jeremy Narby
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Time, Love, Memory
- A Great Biologist and His Quest for the Origins of Behavior
- By: Jonathan Weiner
- Narrated by: Kevin Pariseau
- Length: 11 hrs and 37 mins
- Unabridged
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Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch, brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.
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This is a profound science book
- By Timothy A. Smith on 05-12-10
By: Jonathan Weiner
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A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- By: Jennifer A. Doudna, Samuel H. Sternberg
- Narrated by: Erin Bennett
- Length: 9 hrs and 22 mins
- Unabridged
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Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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In to the abyss we ascend, a scary future
- By Philomath on 06-17-17
By: Jennifer A. Doudna, and others
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13 Things That Don't Make Sense
- The Most Baffling Scientific Mysteries of Our Time
- By: Michael Brooks
- Narrated by: James Adams
- Length: 8 hrs and 58 mins
- Unabridged
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Science starts to get interesting when things don't make sense. Science's best-kept secret is that there are experimental results and reliable data that the most brilliant scientists can neither explain nor dismiss. If history is any precedent, we should look to today's inexplicable results to forecast the future of science. Michael Brooks heads to the scientific frontier to meet 13 modern-day anomalies and discover tomorrow's breakthroughs.
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10 interesting chapters-read epiloge first
- By Stephen on 06-10-09
By: Michael Brooks
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Headstrong
- 52 Women Who Changed Science-and the World
- By: Rachel Swaby
- Narrated by: Lauren Fortgang
- Length: 7 hrs and 1 min
- Unabridged
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In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation.
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Role models for young women
- By mtsuda90 on 06-25-16
By: Rachel Swaby
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The Upright Thinkers
- The Human Journey From Living in Trees to Understanding the Cosmos
- By: Leonard Mlodinow
- Narrated by: Leonard Mlodinow
- Length: 12 hrs and 29 mins
- Unabridged
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In this fascinating and illuminating work, Leonard Mlodinow guides us through the critical eras and events in the development of science, all of which, he demonstrates, were propelled forward by humankind's collective struggle to know. From the birth of reasoning and culture to the formation of the studies of physics, chemistry, biology, and modern-day quantum physics, we come to see that much of our progress can be attributed to simple questions - why? how? - bravely asked.
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10/10 Got What I Wanted.
- By Austin on 09-22-15
By: Leonard Mlodinow
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Evolution
- The Remarkable History of a Scientific Theory
- By: Edward J. Larson
- Narrated by: John McDonough
- Length: 9 hrs and 41 mins
- Unabridged
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Edward J. Larson is a Pulitzer Prize-winning author and eminent science historian. This marvelously readable, yet sumptuously erudite work traces the development of the scientific theory of evolution. From Darwin's essential trip to the Galápagos, to the most contemporary studies in sociobiology, this work takes listeners both into the field and laboratories of the world's greatest evolutionary scientists, and shows how the theory of evolution has itself evolved.
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An Excellent History!
- By Bradly D. Elder on 08-13-07
By: Edward J. Larson
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The Lives of a Cell
- Notes of a Biology Watcher
- By: Lewis Thomas
- Narrated by: Grover Gardner
- Length: 4 hrs and 12 mins
- Unabridged
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In The Lives of a Cell, Dr. Lewis Thomas opens up to the listener a universe of knowledge and perception that is perhaps not wholly unfamiliar to the research scientist; but the world he explores is also one of men and women, of complex interrelationships, old ironies, peculiar powers, and intricate languages that give identity to the alienated and direction to the dependent. This remarkable work offers a subtle, bold vision of humankind and the world around us - a sense of what gives life - from a writer who seems to draw grace and strength from the very substance of his subject.
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So enlightening and enjoyable!
- By Flora on 03-15-18
By: Lewis Thomas
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Brief Candle in the Dark
- My Life in Science
- By: Richard Dawkins
- Narrated by: Richard Dawkins
- Length: 13 hrs and 53 mins
- Unabridged
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In this hugely entertaining sequel to the New York Times best-selling memoir An Appetite for Wonder, Richard Dawkins delves deeply into his intellectual life spent kick-starting new conversations about science, culture, and religion and writing yet another of the most audacious and widely read books of the 20th century - The God Delusion.
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I'm a Dawkins Groupie but...
- By Anne on 10-18-15
By: Richard Dawkins
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In the beginning, Earth was an inhospitably alien place—in constant chemical flux, covered with churning seas, crafting its landscape through incessant volcanic eruptions. Amid all this tumult and disaster, life began. The earliest living things were no more than membranes stretched across microscopic gaps in rocks, where boiling hot jets of mineral-rich water gushed out from cracks in the ocean floor. In A (Very) Short History of Life on Earth, Henry Gee zips through the last 4.6 billion years with infectious enthusiasm and intellectual rigor.
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incredibly annoying
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A Short History of Humanity
- A New History of Old Europe
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Johannes Krause is the director of the Max Planck Institute for Evolutionary Anthropology and a brilliant pioneer in the field of archaeogenetics - archaeology augmented by DNA sequencing technology - which has allowed scientists to reconstruct human history reaching back hundreds of thousands of years before recorded time. In this surprising account, Krause and journalist Thomas Trappe rewrite a fascinating chapter of this history, the peopling of Europe, that takes us from the Neanderthals and Denisovans to the present.
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Not a short history of humanity
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Genetics for Dummies
- 3rd Edition
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With rapid advances in genomic technologies, genetic testing has become a key part of both clinical practice and research. Scientists are constantly discovering more about how genetics plays a role in health and disease, and healthcare providers are using this information to more accurately identify their patients' particular medical needs. Genetic information is also increasingly being used for a wide range of non-clinical purposes, such as exploring one's ancestry.
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Pass On This One
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By: Tara Rodden Robinson PhD, and others
What listeners say about The Tangled Tree
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- R. Sloup
- 08-12-21
great balance for scientist or anyone
lots of context that would be hard to get without tons of reading. lots of details that tell you about the nuance of science and success
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- Linda
- 01-02-20
for those who love biology
there are two stories in this book: one about Carl Woese and a second about genetics. I enjoyed them both.
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- Paul Skaar
- 12-31-19
wow! best audio book ever made.
a wonderfully well written science story read perfectly. Mr. Roy brings so much to the writing that I expect he'll get an Audie at some point. Mr. Quammen takes us on a marvelous tour that starts with a carefully crafted escalator rise to a comprehensive vantage point. He then hands us thrilling understanding with ease. this is a feat of science writing to set a new bar and it is read so well that I can't think of an appropriate comparison.
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- Max
- 09-18-18
exceptional
exceptional. i am a researcher in the field and the science here is exceptional. much appreciation.
and i also loved the acting.
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8 people found this helpful
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- Elliot
- 01-18-19
More a history of personalities than a treatise on Horizontal gene transfer
Horizontal gene transfer is exciting field. David Quammen clearly understands the material but felt inclined to heavily focus on the scientists involved in the field. He also sketches a history of how our knowledge of general evolution evolved. Understandably, HGT would be too dry without weaving in the personalities of the scientists involved. But the book would be a lot shorter and more focused.
Jacques Roy does the book justice and utilizes an array of accents to portray quotes from English, French and German scientists. He narrates flawlessly but with a somewhat whispering voice as if sharing a secret.
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- Ian K O'Malley
- 06-07-20
Evolutionary Science revisited
This a great review of current evolutionary thought. I was captivated by the many new avenues of study under the large umbrella of Evolutionary Science...
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- Robert
- 03-29-19
Fine book on a complex topic
David Quammen is skillful and engaging as he helps curious non-sceintists grasp what would otherwise be impenetrably complex matters in biology and evolution. Here he starts with the familiar Tree of Life, proposed by Darwin as a helpful metaphor for his theory of how plants and animals change over time and produce new and ever more varied species that diverge and branch from the ancestral trunk. He then shows how recent generations of researchers have complicated this way of representing biological change. They have discovered life forms that defy existing categories. They have found evidence that symbiosis plays a larger role in the creation of new species than was previously understood. And they have discovered mechanisms of gene transfer among species that are direct, horizontal and, since they bypass reproduction, non-Darwinian. Indeed these discoveries complicate the very concept of discrete species and of discrete individuals within a species. It's dizzying and disorienting, but in a good way.
One minor complaint about Jacques Roy's generally good reading of the book: He, or perhaps his producer, decided to render quotations from the writings of German, French and British scientists in foreign accents. The accents aren't at all convincing, but even if they were, such characterizations are unnecessary and distracting in a work of this kind.
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- Andy Capo
- 10-10-18
Entertaining and facenating.
Loved every minute of it. I was entertained while being educated on a subject that I was surprised to learn I knew so little about.
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- D. Squires
- 12-23-18
evolution revisited
having last studied evolution 30 years ago... this refresher was a delight. particularly entertaining as a view into the personal foibles of the brilliant people who pushed this science forward.
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- MalcT
- 12-20-19
Enjoyable tracing of development of genetics
Could have been a "Darwin creation" basher but avoided the trap - traces the development of ideas and hypotheses in genetics accepting the failing of some scientists to use "faith" when techniques were not available to prove or disprove their theories at that time - easy to listen to and follow arguments
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