Best friends Annie and Sarah need cash - fast. Sarah, a beautiful, successful lawyer, wants nothing more than to have a baby. But balancing IVF treatments with a grueling eighty-hour workweek is no walk in the park. Meanwhile, Annie, a Harvard-grad chemist recently transplanted to Southern California, is cutting coupons to afford her young autistic son's expensive therapy.

After three marriages and a lot of living, resilient Billie Slate knows exactly what trouble love can bring. Now she’s reinvented herself as the Heartbreak Bunny, an on-call performance artist who can heal anyone who’s been burned by that four-letter word, LOVE, by hopping about and whisking away sad mementos from their past relationships. Call it magic. Call it peculiar. But her bunny costume is as perfect as her breakup mantra: SNAP OUT OF IT.

Every day Iona, a larger-than-life magazine advice columnist, travels the ten stops from Hampton Court to Waterloo Station by train, accompanied by her dog, Lulu. Every day she sees the same people, whom she knows only by nickname: Impossibly-Pretty-Constant-Reader and Terribly-Lonely-Teenager. Of course, they never speak. Seasoned commuters never do. Then one morning, the man she calls Smart-But-Sexist-Manspreader chokes on a grape right in front of her. He’d have died were it not for the timely intervention of Sanjay, a nurse, who gives him the Heimlich maneuver.

Sasha has had it. She cannot bring herself to respond to another inane, “urgent” email or participate in the corporate employee joyfulness program. She hasn’t seen her friends in months. Sex? Seems like a lot of effort. Even cooking dinner takes far too much planning. Sasha has hit a wall. Armed with good intentions to drink kale smoothies, try yoga, and find peace, she heads to the seaside resort she loved as a child. But it’s the off season, the hotel is in a dilapidated shambles, and she has to share the beach with the only other occupant: a grumpy guy named Finn.

Connie McColl is finally free to make her own decisions for the first time in decades. And when she meets glamorous Gill and downtrodden Maggie, at a rather dull flower arranging class, it seems that she’s not the only one dreaming of adventure. The three very different women all agree it’s about time they had a holiday to remember. So they make a pact for this summer to be their best yet - and drive off into the sunset together....

Wife. Mother. Breadwinner. Penelope Ruiz-Kar is doing it all - and barely keeping it together. Meanwhile, her best friend, Jenny Sweet, appears to be sailing through life. As close as the two women are, Jenny’s passionate marriage, pristine house, and ultra-polite child stand in stark contrast to Penelope’s underemployed husband, Sanjay, their unruly brood, and the daily grind she calls a career.

Marcy Hammer's life has been turned upside down. Her husband, the head of a global brassiere empire, didn't think twice about leaving her after thirty-three years of marriage for a 32DD lingerie model. Now Harvey the Home-Wrecker is missing in action, but Marcy's through thinking about what a cliché he is. What she needs now is a party-size bag of potato chips, a good support system, and a new dress.

Phronsie Linnelle was conceived at Woodstock in a serendipitous liaison between a free-spirited hippie and a farmer’s son and was born with magical wonder flickering in her DNA and rationality knit into her bones. All her life she’s been torn between the two. But now that she’s been betrayed by both love and the mother she once idolized, her rational side is winning. So when her best friend from childhood proposes that they give up on romance and marry each other, Phronsie agrees.

At fifty-three, Maggie Harris has a good marriage and two mostly happy children. Perpetually anxious, she’s also accumulated a list of semi-reasonable fears: falling air conditioners, the IRS, identity theft, skydiving, and airbag recalls. But never once did Maggie worry that her husband of nearly thirty years would leave her.

As Martine and Jacques Le Guennec prepare for their annual family Christmas dinner, Martine reminds her husband to be on his best behavior. Their son Nicolas is bringing his girlfriend, Jeanne, to their home for the first time, and she doesn't want Jacques to scare this one off. Jacques has always ruled his roost with patriarchal bravado, and he can't help but verbally antagonize everyone - especially the wives of his sons.

Nora Hamilton knows the formula for love better than anyone. As a romance channel screenwriter, it’s her job. But when her too-good-to work husband leaves her and their two kids, Nora turns her marriage’s collapse into cash and writes the best script of her life. No one is more surprised than her when it’s picked up for the big screen and set to film on location at her 100-year-old-home. When former Sexiest Man Alive, Leo Vance, is cast as her ne’er do well husband Nora’s life will never be the same.

When Ruby woke up on her tenth birthday, something about her had changed. Something alarming enough to make her parents lock her in the garage and call the police. Something that got her sent to Thurmond, a brutal government "rehabilitation camp." She might have survived the mysterious disease that killed most of America's children, but she and the others emerged with something far worse: frightening abilities they cannot control. Now sixteen, Ruby is one of the dangerous ones.

Meet Nell. Her life is a mess. When her business goes bust and her fiancé with it, Nell's happy ever after in California falls apart and she moves back to London to start over. But a lot has changed since she’s been gone. All her single friends are now married with children, a sky-high real estate market forces her to rent a room in a stranger’s house, and everyone has seemingly perfect Instagram-ready lives. Starting from scratch she feels like a f**k up . . . a forty-something f**k up.

Savannah Cade's dreams are coming true. The Claire Donovan, editor-in-chief of the most successful romance publishing company in the country, has requested to see the manuscript Savannah's been secretly writing. The only problem: she's an editor for a different company, and their philosophy is only highbrow works are worth printing and romance should be reserved for the lowest level of Dante's inferno.

Lillian and Madison were unlikely roommates and yet inseparable friends at their elite boarding school. But then, Lillian had to leave the school unexpectedly in the wake of a scandal, and they’ve barely spoken since. Until now, when Lillian gets a letter from Madison pleading for her help. Madison’s twin stepkids are moving in with her family, and she wants Lillian to be their caretaker. However, there’s a catch: The twins spontaneously combust when they get agitated, flames igniting from their skin in a startling but beautiful way.