Many know Kimberly Williams-Paisley as the bride in the popular Steve Martin remakes of the Father of the Bride movies, the calculating Peggy Kenter on Nashville, or the wife of country megastar Brad Paisley. But in 2014, Williams-Paisley revealed a tragic secret: Her mother had been diagnosed with a rare form of dementia called primary progressive aphasia at the age of 61.

Talking about death and dying is considered taboo in polite company, and even in the medical field. Our ideas about dying are confusing at best: Will our memories flash before our eyes? Regrets consume our thoughts? Does a bright light appear at the end of a tunnel? For most people, it will be a slower process, one eased with preparedness, good humor, and a bit of faith. At the forefront of changing attitudes around palliative care is hospice nurse Hadley Vlahos, who shows that end-of-life care can teach us just as much about how to live as it does about how we die.

In the summer after graduating from college, Suleika Jaouad was preparing, as they say in commencement speeches, to enter “the real world”. She had fallen in love and moved to Paris to pursue her dream of becoming a war correspondent. The real world she found, however, would take her into a very different kind of conflict zone. It started with an itch - first on her feet, then up her legs, like a thousand invisible mosquito bites. Then a trip to the doctor and, a few weeks shy of her 23rd birthday, a diagnosis: leukemia, with a 35 percent chance of survival.

William Waters grew up in a house silenced by tragedy, where his parents could hardly bear to look at him, much less love him—so when he meets the spirited and ambitious Julia Padavano in his freshman year of college, it’s as if the world has lit up around him. With Julia comes her family, as she and her three sisters are inseparable: Sylvie, the family’s dreamer, is happiest with her nose in a book; Cecelia is a free-spirited artist; and Emeline patiently takes care of them all.

Fans know her as the spoiled, rich cheerleader Lyla Garrity on Friday Night Lights or as the affluent, mysterious Samantha on the HBO megahit Euphoria. But as revealed for the first time in this book, Minka Kelly’s life has been anything but easy. Raised by a single mother who worked as a stripper and struggled with addiction, Minka spent years waking up in strange apartments as she and her mom bounced around the country, relying on friends and relatives to take them in. Now an established actress and philanthropist, Minka takes this next step in her career as a writer.

Laila Tarraf was the chief people officer for Peet’s Coffee and Tea, the iconic Berkeley coffee roaster, but she had a secret: She was failing in the most important relationships in her life. Yes, she was a strong and effective business leader, the successful daughter of immigrants, and the mother of a toddler, but she was disconnected from her own feelings ­and had little patience for those of others. All that changed, however, when three of the people most important to her - her husband, father, and mother - died in quick succession.

While on her way to teach a yoga retreat in March 2014, Rachel Brathen collapses at an airport, brought to her knees by excruciating stomach pains. She is rushed to the hospital on the tiny island of Bonaire and hours later forced to undergo surgery. When she wakes up from anesthesia, her boyfriend is weeping at her bedside. While Rachel was struck down with seemingly mysterious pain, her best friend, Andrea, sustained fatal injuries as a result of a car accident. Rachel and Andrea had a magical friendship.

For Lewis and Wren, their first year of marriage is also their last. A few weeks after their wedding, Lewis receives a rare diagnosis. He will retain most of his consciousness, memories, and intellect, but his physical body will gradually turn into a great white shark. As Lewis develops the features and impulses of one of the most predatory creatures in the ocean, his complicated artist’s heart struggles to make peace with his unfulfilled dreams.

When Alice Greczyn's parents felt called by God to exchange worldly employment for heavenly provision, they followed their faith into homelessness with five children and a cat in tow. Homeschooled and avowed never to kiss a man until her wedding day, Alice had plans to escape by becoming a missionary nurse—plans that were put on hold with the opening of an unexpected door: the opportunity to be a Hollywood actress. What followed was a test of faith unlike any she had prepared for, one that forced her to learn to survive without the only framework for life she had ever known.

In an audiobook that is The Big Sick meets Dad Is Fat, Jeannie Gaffigan, writer/director/producer/accused supermom and wife of best-selling author/comedian Jim Gaffigan, writes with humor and heart about the pear-sized brain tumor she had removed, the toll it took on her enormous family, and the priceless lessons she learned along the way.

Laurel Braitman spent her childhood learning from her dad how to out-fish grown men, keep bees, and fix carburetors. Diagnosed young with terminal cancer, he raced against the clock to leave her the skills she’d need to survive without him. This was one legacy. Another was relentless perfectionism and the belief that bravery meant never acknowledging your own fear. By her mid-thirties Laurel is a ship about to splinter on the rocks, having learned the hard way that no achievement can protect her from pain or remove the guilt and regret her dad’s death leaves her with.

I got tired. Tired of all the fluffy, just-guessing books about what people regret, want, and will do at the end of their life. I'm a hospice nurse and I want to show the world how love can be messy, not-pretty, complicated, funny, fun and heart-breakingly beautiful. I want the world to know that caring for someone who's dying is challenging and this is where you discover your true self.

When their only child was diagnosed with cystic fibrosis (CF) at the age of two, Maryanne O'Hara and her husband were told that Caitlin could live a long life or be dead in a matter of months. Thirty-one years later, Caitlin lost her battle with this devastating disease following an excruciating two-year wait on the transplant list and a last-minute race to locate a pair of healthy lungs. The sudden spiral of events left Maryanne in an existential crisis, searching to find an answer to the eternal question: Why we are here?

In an idyllic Los Angeles neighborhood, where generations enjoy deep roots in old homes, the O’Rourke family fits right in. Miriam and Craig are both artists and their four children carry on the legacy. When their teenage son, Nick, is diagnosed with schizophrenia, a tumultuous decade ensues in which the family careens off the conventional course. Like the 10 Biblical plagues, they are hit by one catastrophe after another: violence, evictions, arrests, a suicide attempt, a near-drowning - even cancer and a brain tumor - play against the backdrop of a wild teenage bacchanal.

When Bozoma Saint John's husband, Peter, died of cancer, she made one big decision: to live life urgently. Bozoma was no stranger to adversity, having lost her college boyfriend to suicide, navigated an interracial marriage, grieved a child born prematurely—a process that led to her and Peter's separation—and coparented the daughter who she and Peter shared.