From an award-winning Fortune reporter, an explosive narrative investigation of the generic drug boom that reveals the life-threatening dangers posed by globalization - The Jungle for pharmaceuticals.

Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by Purdue Pharma’s aggressive marketing of OxyContin. Families, working class and wealthy, have been torn apart, businesses destroyed, and public officials pushed to the brink. Meanwhile, the drugmaker’s owners, Raymond and Mortimer Sackler, whose names adorn museums worldwide, made enormous fortunes from the commercial success of OxyContin.

The United States spends an excess $1.5 trillion annually on health care compared to other wealthy countries—yet the amount of time that Americans live in good health ranks a lowly 68th in the world. At the heart of the problem is Big Pharma, which funds most clinical trials and therefore controls the research agenda, withholds the real data from those trials as corporate secrets, and shapes most of the information relied upon by health care professionals.

When police in Rexburg, Idaho perform a wellness check on seven-year-old J.J. Vallow and his sister, sixteen-year-old Tylee Ryan, both children are nowhere to be found. Their mother, Lori Vallow, gives a phony explanation, and when officers return the following day with a search warrant, she, too, is gone. As the police begin to close in, a larger web of mystery, murder, fanaticism and deceit begins to unravel. Vallow’s case is sinuously complex. As investigators prod further, they find the accused Black Widow has an unusual number of bodies piling up around her.

The prize-winning and best-selling author of Say Nothing presents a grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

Lee Johnson was a man with simple dreams. He never imagined that he would become the face of a David-and-Goliath showdown against one of the world's most powerful corporate giants. But a workplace accident left Lee doused in a toxic chemical and facing a deadly cancer that turned his life upside down. In 2018, the world watched as Lee was thrust to the forefront of one the most dramatic legal battles in recent history. The Monsanto Papers takes listeners behind the scenes of a grueling legal battle, pulling back the curtain on the frailties of the American court system.

Science is a force for good in the world—at least usually. But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn’t everything, it’s the only thing—no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process.

As a Yale School of Medicine physician, the New York Times best-selling author of Every Patient Tells a Story, and an inspiration and adviser for the hit Fox TV drama, House, M.D., Lisa Sanders has seen it all. And yet, she is often confounded by the cases she describes in her column: unexpected collections of symptoms that she and other physicians struggle to diagnose. Dr. Sanders shows how making the right diagnosis requires expertise, painstaking procedure, and sometimes a little luck.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".

In the tradition of The Glass Castle, Educated, and Heartland, Neal Wooten traces five decades of his dirt-poor, Alabama mountain family as the years and secrets coalesce.

In the slums of 1880s New York, Una Kelly has grown up to be a rough-and-tumble grifter, able to filch a pocketbook in five seconds flat. But when another con-woman pins her for a murder she didn't commit, Una is forced to flee. Running from the police, Una lies her way into an unlikely refuge: the nursing school at Bellevue Hospital.

In today's turbulent and volatile marketplace, even the most experienced professionals are struggling with the rapid commoditization of their complex, high-value solutions. The complexity of the problems to be solved and the competitive threats we face are increasing at an alarming rate. At the same time, your customers are wrestling with mission-critical decisions and evaluating solutions that all sound the same and come packaged with a high degree of risk and a low probability of success. Your success demands an exceptional strategy and precise execution that must clearly set you apart from your competition.

From the moment the first machine gun rang out over the Western Front, one thing was clear: mankind’s military technology had wildly surpassed its medical capabilities. Bodies were battered, gouged, hacked, and gassed. The First World War claimed millions of lives and left millions more wounded and disfigured. In the midst of this brutality, however, there were also those who strove to alleviate suffering. The Facemaker tells the extraordinary story of such an individual: the pioneering plastic surgeon Harold Gillies.

Two days after Christmas, 2011, Russel Faria returned to his Troy, Missouri, home to find his wife, Betsy, dead, a knife still lodged in her neck. She had been stabbed 55 times in a brutal murder that would set off a chain of events leading to one man's wrongful conviction and imprisonment, another man's death, the revelation of a diabolical scheme, and an astounding miscarriage of justice left unresolved for another 10 years.

In 1968, Bruce Tucker, a Black man, went into Virginia’s top research hospital with a head injury, only to have his heart taken out of his body and put into the chest of a White businessman. Now, in The Organ Thieves, Pulitzer Prize-nominated journalist Chip Jones exposes the horrifying inequality surrounding Tucker’s death and how he was used as a human guinea pig without his family’s permission or knowledge.

Dr. Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys' club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried.

After Hurricane Katrina struck and power failed, amid rising floodwaters and heat, exhausted staff at Memorial Medical Center designated certain patients last for rescue. Months later, a doctor and two nurses were arrested and accused of injecting some of those patients with life-ending drugs.

The universal instinct is to run from an outbreak of disease. These doctors run toward it. They always keep a bag packed. They seldom have more than 24 hours before they are dispatched. They are told only their country of destination and the epidemic they will tackle when they get there.

In the spring of 2020, COVID-19 arrived in New York City. Before long, America’s largest metropolis was at war against a virus that mercilessly swept through its five boroughs. In The Desperate Hours, award-winning journalist Marie Brenner, having been granted unprecedented 18-month access to the entire New York-Presbyterian hospital system, tells the story of the doctors, nurses, residents, researchers, and suppliers who tried to save lives across Manhattan, Queens, and Brooklyn and the northern periphery of the city.

The opioid epidemic has been described as "one of the greatest mistakes of modern medicine." But calling it a mistake is a generous rewriting of the history of greed, corruption, and indifference that pushed the US into consuming more than 80 percent of the world's opioid painkillers. Journeying through lives and communities wrecked by the epidemic, Chris McGreal reveals not only how Big Pharma hooked Americans on powerfully addictive drugs but the corrupting of medicine and public institutions that let the opioid makers get away with it.

A riveting, powerful telling of the story of the grassroots movement of activists, many of them in a life-or-death struggle, who seized upon scientific research to help develop the drugs that turned HIV from a mostly fatal infection to a manageable disease. Ignored by public officials, religious leaders, and the nation at large, and confronted with shame and hatred, this small group of men and women chose to fight for their right to live by educating themselves and demanding to become full partners in the race for effective treatments.

Returning to practice after a suspension for stealing opioids, a young doctor takes the only job he can find: a post as a physician at the struggling St. Luke's Hospital in east London. Amid the maelstrom of sick patients, overworked staff and underfunded wards, a more insidious secret soon declares itself: too many patients are dying. And a murderer may be lurking in plain sight.

Dr. Marty Makary is co-developer of the life-saving checklist outlined in Atul Gawande's best-selling The Checklist Manifesto. As a busy surgeon who has worked in many of the best hospitals in the nation, he can testify to the amazing power of modern medicine to cure. But he's also been a witness to a medical culture that routinely leaves surgical sponges inside patients, amputates the wrong limbs, and overdoses children because of sloppy handwriting. Over the last 10 years, neither error rates nor costs have come down, despite scientific progress.

Exploring the steroid-fueled world of professional wrestling, this riveting chronicle lays bare the devastating events that led to the 2007 murder-suicide of Chris Benoit, his wife Nancy, and their seven-year-old son, Daniel.

A seemingly perfect world held an even more unlikely killer... Julie Keown had a great job, financial security, and a perfect husband who was attending Harvard Business School. But after Julie suddenly died, and doctors discovered she’d been poisoned with the main ingredient in antifreeze, her parents began to suspect that her husband, James, was not so perfect. This blow-by-blow account shows how investigators and state police unraveled James Keown’s chilling web of deceit.

Not since The Thin Blue Line has there been a true-crime saga as engrossing as Making a Murderer. Captivating audiences across demographic lines, it made Steven Avery a household name and thrust defense attorney Jerome F. Buting - and his fight against America's dysfunctional criminal justice system - into the spotlight. In Illusion of Justice, Buting uses the Avery case as a springboard to examine the shaky integrity of our law enforcement and legal systems, which he has witnessed firsthand for nearly four decades.

One in five Americans now has medical debt in collections and rising health care costs today threaten every small business in America. Dr Makary, one of the nation's leading health care experts, travels across America and details why health care has become a bubble. Drawing from on-the-ground stories, his research and his own experience, The Price We Pay paints a vivid picture of price-gouging, middlemen and a series of elusive money games in need of a serious shake-up.

In The Poisoner's Handbook, Blum draws from highly original research to track the fascinating, perilous days when a pair of forensic scientists began their trailblazing chemical detective work, fighting to end an era when untraceable poisons offered an easy path to the perfect crime.

Strictly off limits to the public, Plum Island is home to virginal beaches, cliffs, forests, ponds - and the deadliest germs that have ever roamed the planet. Lab 257 blows the lid off the stunning true nature and checkered history of Plum Island. It shows that the seemingly bucolic island in the shadow of New York City is a ticking biological time bomb that none of us can safely ignore.