Wendy Mitchell had a busy job with the British National Health Service, raised her two daughters alone, and spent her weekends running and climbing mountains. Then, slowly, a mist settled deep inside the mind she once knew so well, blurring the world around her. She didn’t know it then, but dementia was starting to take hold. In 2014, at age 58, she was diagnosed with young-onset Alzheimer’s. In this groundbreaking book, Mitchell shares the heartrending story of her cognitive decline and how she has fought to stave it off.

After getting a master’s degree in clinical psychology, Dasha Kiper became the live-in caregiver for a Holocaust survivor with Alzheimer’s disease. For a year, she endured the emotional strain of looking after a person whose condition disrupts the rules of time, order, and continuity. Inspired by her own experience and her work counseling caregivers in the subsequent decade, Kiper offers an entirely new way to understand the symbiotic relationship between patients and those tending to them.

Restaurateur, magazine publisher, celebrity chef, and nationally known lifestyle maven, B. Smith is struggling at 66 with a tag she never expected to add to that string: Alzheimer's patient. She's not alone. Every 67 seconds someone newly develops it, and millions of lives are affected by its aftershocks.

“Any story that starts will also end.” As a writer, Ann Patchett knows what the outcome of her fiction will be. Life, however, often takes turns we do not see coming. Patchett ponders this truth in these wise essays that afford a fresh and intimate look into her mind and heart.

This Close to Happy is the rare, vividly personal account of what it feels like to suffer from clinical depression, written from a woman's perspective and informed by an acute understanding of the implications of this disease over a lifetime. Taking off from essays on depression she has written for The New Yorker and The New York Times Magazine, Daphne Merkin casts her eye back to her beginnings to try to sort out the root causes of her affliction.

Inheritance is an audiobook about secrets - secrets within families, kept out of shame or self-protectiveness; secrets we keep from one another in the name of love. It is the story of a woman's urgent quest to unlock the story of her own identity, a story that has been scrupulously hidden from her for more than 50 years, years she had spent writing brilliantly, and compulsively, on themes of identity and family history.

Regarded as one of the finest journalists of her generation, Mamie Baird Magnusson's whole life was a celebration of words - words that she fought to retain in the grip of a disease which is fast becoming the scourge of the 21st century. Married to writer and broadcaster Magnus Magnusson, they had five children of whom Sally is the eldest.

The inimitably witty David Rakoff, New York Times best-selling author of Don’t Get Too Comfortable, defends the commonsensical notion that you should always assume the worst, because you’ll never be disappointed. In this deeply funny (and, no kidding, wise and poignant) audiobook, Rakoff examines the realities of our sunny, gosh­ everyone-can-be-a-star contemporary culture and finds that, pretty much as a universal rule, the best is not yet to come, adversity will triumph, justice will not be served, and your dreams won’t come true.

When Wayne and Kelly Maines adopted identical twin boys, they thought their lives were complete. But it wasn't long before they noticed a marked difference between Jonas and his brother, Wyatt. Jonas preferred sports and trucks and many of the things little boys were "supposed" to like; but Wyatt liked princess dolls and dress-up and playing Little Mermaid. By the time the twins were toddlers, confusion over Wyatt's insistence that he was female began to tear the family apart.

As a young dad, Bruce Feiler, New York Times best-selling author and television host, received shattering news. A rare form of cancer was threatening not only his life but his family's future as well. A singular question emerged: Who would be there for his wife and daughters if he were gone? Feiler reached out to six extraordinary men who helped shape him and asked them to be present in the lives of his daughters. The Council of Dads is the unforgettable portrait of these men, who offer wisdom, humor, and guidance on how to live, love, question, and dream.

Born in the Philippines, young Grace Talusan moves with her family to a New England suburb in the 1970s. At school, she confronts racism as one of the few kids with a brown face. At home, the confusion is worse: her grandfather's nightly visits to her room leave her hurt and terrified, and she learns to build a protective wall of silence that maps onto the larger silence practiced by her Catholic Filipino family. Later, she learns that her family history is threaded with violence and abuse. Despite all this, she finds love, and success as a teacher.

Native Country of the Heart is the writer and activist Cherrie Moraga's love letter to her "unlettered" mother. It begins with her mother, Elvira Isabel Moraga, who as a child, along with her siblings, was hired out by her own father to pick cotton in California's Imperial Valley. The lives of Cherrie and her mother, and of their people, are woven together in a story of critical reflection and deep personal revelation as Moraga charts her own coming to consciousness alongside the heartbreaking story of her mother's decline.

Lauren Marks was 27 when an aneurysm ruptured in her brain and left her fighting for her life. She woke up in a hospital soon after with serious deficiencies to her reading, speaking, and writing abilities, and an unfamiliar diagnosis: aphasia. This would be shocking news for anyone, but Lauren was a voracious reader, an actress, director, dramaturg, and pursuing her PhD. At any other period of her life, this diagnosis would have been a devastating blow. But she woke up...different.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

A mid-century doctor's raw, unvarnished account of his own descent into madness, and his daughter's attempt to piece his life back together and make sense of her own. Texas-born and Harvard-educated, Dr. Perry Baird was a rising medical star in the late 1920s and 1930s. Early in his career, ahead of his time, he grew fascinated with identifying the biochemical root of manic depression, just as he began to suffer from it himself.

This Close to Happy is the rare, vividly personal account of what it feels like to suffer from clinical depression, written from a woman's perspective and informed by an acute understanding of the implications of this disease over a lifetime. Taking off from essays on depression she has written for The New Yorker and The New York Times Magazine, Daphne Merkin casts her eye back to her beginnings to try to sort out the root causes of her affliction.

Moving from her childhood in Oakland and growing up with her Chinese parents through her success as a novelist, Amy Tan delves into her creative interests in music, the paralysis of beginning a new project, journal writing, and travelling. Where the Past Begins chronicles the making of a writer. With characteristic humor and poignant observation, Tan weaves a nontraditional introspective narrative that is as complex and vibrant as this beloved American novelist's fiction.

It's a report tempered by hard times. In "Matricide", Daum unflinchingly describes a parent's death and the uncomfortable emotions it provokes; and in "Diary of a Coma" she relates her own journey to the twilight of the mind. But Daum also operates in a comic register. With perfect precision, she reveals the absurdities of the marriage-industrial complex, of the New Age dating market, and of the peculiar habits of the young and digital.

Native Country of the Heart is the writer and activist Cherrie Moraga's love letter to her "unlettered" mother. It begins with her mother, Elvira Isabel Moraga, who as a child, along with her siblings, was hired out by her own father to pick cotton in California's Imperial Valley. The lives of Cherrie and her mother, and of their people, are woven together in a story of critical reflection and deep personal revelation as Moraga charts her own coming to consciousness alongside the heartbreaking story of her mother's decline.

Lauren Marks was 27 when an aneurysm ruptured in her brain and left her fighting for her life. She woke up in a hospital soon after with serious deficiencies to her reading, speaking, and writing abilities, and an unfamiliar diagnosis: aphasia. This would be shocking news for anyone, but Lauren was a voracious reader, an actress, director, dramaturg, and pursuing her PhD. At any other period of her life, this diagnosis would have been a devastating blow. But she woke up...different.

At a time when we mourn public figures and national tragedies with hashtags, where intimate posts about loss go viral and we receive automated birthday reminders for dead friends, it's clear we are navigating new terrain without a road map. Let's face it: Most of us have always had a difficult time talking about death and sharing our grief. We're awkward and uncertain; we avoid, ignore, or even deny feelings of sadness; we offer platitudes; we send sympathy bouquets whittled out of fruit.

In the early evening on October 1, 2003, Christina Crosby was three miles into a 17 mile bicycle ride, intent on reaching her goal of 1,000 miles for the riding season. She was a respected senior professor of English who had celebrated her 50th birthday a month before. As she crested a hill, she caught a branch in the spokes of her bicycle, which instantly pitched her to the pavement. Her chin took the full force of the blow, and her head snapped back. In that instant, she was paralyzed.

The complex, deeply binding relationship between mothers and daughters is brought vividly to life in Katie Hafner's remarkable memoir, an exploration of the year she and her mother, Helen, spent working through, and triumphing over, a lifetime of unresolved emotions. Dreaming of a "year in Provence" with her mother, Katie urges Helen to move to San Francisco to live with her and Zoe, Katie's teenage daughter. Katie and Zoe had become a mother-daughter team, strong enough, Katie thought, to absorb the arrival of a 77-year-old woman set in her ways....

A mother who invented her past, a father who was often absent, a son who wondered if this could really be his family...Richard Glover's favourite dinner-party game is called 'Who's Got the Weirdest Parents?' It's a game he always thinks he'll win. There was his mother, a deluded snob who made up large swathes of her past and who ran away with Richard's English teacher, a Tolkien devotee, nudist and stuffed toy collector.

Alexandra Styron's parents—the Pulitzer Prize-winning author of Sophie’s Choice and his political activist wife, Rose—were, for half a century, leading players on the world’s cultural stage. Alexandra was raised under both the halo of her father’s brilliance and the long shadow of his troubled mind. Reading My Father portrays the epic sweep of an American artist’s life. It is also a tale of filial love, beautifully written with humor, compassion, and grace.

Growing up in the small town of Boiling Springs, North Carolina, in the 70’s and 80’s, Linda believes that she is profoundly different from everyone else, including the members of her own family. “What I know about you, little girl, would break you in two” are the cruel, mysterious last words that Linda’s grandmother ever says to her.

The word "shanda" is defined as shame or disgrace in Yiddish. This book, Shanda, tells the story of three generations of complicated, intense twentieth-century Jews for whom the desire to fit in and the fear of public humiliation either drove their aspirations or crushed their spirit. In her deeply engaging, astonishingly candid memoir, author and activist Letty Cottin Pogrebin exposes the fiercely-guarded lies and intricate cover-ups woven by dozens of members of her extended family.

One of the world's 50 living autistic savants is the first and only to tell his compelling and inspiring life story and explain how his incredible mind works. Worldwide, there are fewer than 50 living savants, those autistic individuals who can perform miraculous mental calculations or artistic feats. (Think Dustin Hoffman's character in Rain Man.) None of them has been able to discuss his or her thought processes, much less write a book. Until now.

The noted research psychiatrist explores how life's disappointments and difficulties provide us with the lessons we need to become better, bigger, and more resilient human beings. Adversity is an irreducible fact of life. Although we can and should learn from all experiences, both positive and negative best-selling author Dr. Norman E. Rosenthal believes that adversity is by far the best teacher most of us will ever encounter.

In a narrative that spans geography and time, from the Atlantic Ocean in the 17th century to a correctional institute in Texas in the near future, and told from the perspectives of five very different characters, Speak considers what it means to be human and what it means to be less than fully alive.