When a key witness in an organized crime trial turns up dead in his kitchen with liar and the number two scrawled on his forehead, the FBI assumes the murder was a hit to silence him. Then the calls start coming in - more victims with similar markings and no connection to the mob. As agents Victoria Heslin and Dante Rivera struggle to catch a break in the case, they receive a series of cryptic personal messages from the killer, complicating the investigation.

When a private plane whisks CDC epidemiologist Madeline Hamilton to Washington, DC, for an urgent medical symposium, she knows something significant is underway - but she doesn’t expect to face the most disturbing medical mystery of her career. A debilitating neurological toxin has stricken the children of several political families, and one of them is the son of US President Anna Moreland.

In Los Angeles, FBI counterterrorism agent Quinn Traynor receives an urgent call from CDC agent Madeline Hamilton. She’s discovered the first victim of a lethal, unfamiliar virus. Their joint investigation uncovers an imminent bio-terror attack, and their only hope is to identify the terrorists carrying the disease. With just two days remaining before it’s too late, the FBI and the CDC race to prevent a pandemic. The ensuing nightmare will hit closer to home than they ever anticipated, and one of them will pay an unimaginable price for protecting the country.

Beautiful and brilliant Brooke, a transfer student with a mysterious past, aims to graduate first in her class at Everett and attend medical school. Her classmates and professors are captivated by her achievements and appearance. Only Jessica, a wealthy socialite fueled by prescription pills and a huge case of snobbery, senses there's something not quite right about the perfect student. What happens during a historic blizzard will settle their differences once and for all.

When Penny Matthews, a seven-year-old girl with blonde curls and a gap-toothed smile, goes missing in the Appalachian mountains, Detective Ellie Reeves is called straight to the scene. According to Penny’s parents, their daughter vanished after a picnic by the creek. All that’s left behind is a pink friendship bracelet etched with “Penny”.

The beautiful young woman is perfectly still, curled up in the trunk of the car, her long dark hair hiding her face. Her cotton blouse has ridden up a little, revealing two small dots an inch apart on her back. Just like the others. Guilt has kept FBI Agent Tori Hunter away from her home in Manchester Bay, Minnesota for 20 years, ever since her twin sister disappeared on the Fourth of July, when the girls should have been together. But when she receives an anonymous newspaper clipping about another missing girl, Genevieve, Tori is dragged back to the past.

When secretary Annie Parkes is snatched from the street outside of her workplace, David Kane is tasked with finding her. Strong, highly skilled, and secretive, he’s a loner and an outsider; the only man the military trust to find Annie before her kidnappers make good on their promise to kill her. But as Kane pulls Annie from a derelict building, gunshots ringing through the deserted streets around them, he realizes rescuing her is just the beginning. He needs to keep her close to find out who is behind her capture, and to keep her safe.

When Detective Madison Harper arrives at a remote summer camp in Shadow Falls, Northern California, her heart breaks for Jenny, the sweet little girl last seen splashing in the lake with her friends before she vanished. Peering into the silent cabins filled with rows of neatly made beds, Madison knows this idyllic place is hiding a terrible secret.

In the remote forests of Stillwater, Minnesota, you can scream for days and no one will hear you. So when the bodies of two 15-year-old girls are discovered frozen in the snow, Special Agent Nikki Hunt is sure the killer is local: Someone knew where to hide the girls and thought they would never be found. Though Nikki hasn’t been home in 20 years, she knows she must take over the case.

When a man is shot in the head, Bree Taggert and her new partner, veteran detective Dana Romano, respond to the call. They break the news to the victim’s ex-wife and learn the estranged couple’s five-year-old daughter was supposed to have been with him. What starts as a murder investigation quickly morphs into a desperate search for a missing child. The case stirs memories of Bree’s own traumatizing childhood. To find the little girl, Bree will have to relive her own terrifying past.

An eight-year-old girl, Chelsea Compton, is missing in Pine Valley, California, and for Detective Katie Scott it’s a cruel reminder of the friend who disappeared from summer camp 20 years ago. Unable to shake the memories, Katie vows she won’t rest until she discovers what happened to Chelsea. But as Katie starts to investigate, the case reveals itself to be much bigger and more shocking than she feared. Hidden deep in the forest she unearths a makeshift cemetery: a row of graves, each with a brightly colored teddy bear.

It was Beth Katz’s serial killer father who made her like she is: a successful FBI agent and an unstoppable vigilante dedicated to hunting down murderers who have evaded capture. Beth will push herself to the limits to deliver justice. Even if it means killing those who deserve to die.

When the body of a woman is found hanging from a tree in her front garden, rookie Detective Morgan Brookes is first on the scene. But Olivia Potter is past saving. And when her husband and daughters cannot be traced, Morgan knows there is more to this tragedy. And then she finds them. Lying huddled together in the dark basement, each of their faces covered with a small cotton cloth, their bodies cold to the touch. But as Morgan kneels beside the family, she realizes that one of the girls is still breathing.

Frankie Elkin is an average middle-aged woman, a recovering alcoholic with more regrets than belongings. But she spends her life doing what no one else will - searching for missing people the world has stopped looking for. When the police have given up, when the public no longer remembers, when the media has never paid attention, Frankie starts looking. A new case brings her to Mattapan, a Boston neighborhood with a rough reputation. She is searching for Angelique Badeau, a Haitian teenager who vanished from her high school months earlier.

Nicole Cutty and Megan McDonald are both high school seniors in the small town of Emerson Bay, North Carolina. When they disappear from a beach party one warm summer night, police launch a massive search. No clues are found, and hope is almost lost until Megan miraculously surfaces after escaping from a bunker deep in the woods. A year later the best-selling account of her ordeal has turned Megan from local hero to national celebrity.

After the killing of a prominent mob lawyer, NYPD homicide detectives Jacob Jackson and Caitlin Grimes start receive chilling, written “rules” for how to commit the perfect murder. "Rule number one for the perfect murder: Evidence is your enemy. Leave none behind." Jackson (Reid Scott) and Grimes (Cobie Smulders) race to find the killer, setting them on a collision course with the city’s crime underbelly, and a perpetrator who seems happy to toy with them. “Rule number two. No crimes of passion. The perfect murder is always business, never pleasure.”

Kidnappers grabbed Jenna in broad daylight, right in front of her children and their horrified classmates. Her family was issued an insane ransom demand: $25 million in cash and jewels, payable by the end of the school day, otherwise they’ll never see her again. As Jenna’s mother scrambles to gather the money, detectives Mo Butler and George Ortega follow the trail of the kidnappers, which will lead them through a sordid landscape of jealous lovers, broken dreamers, and twisted schemers. But every second counts, and there’s one thing Jenna Wade doesn’t have: very much time.

When Heather McKinley dreamed of becoming a doctor, she imagined curing sick kids and sporting pink stethoscopes. She never anticipated the sleepless nights, grueling exams, and endless labs. And she certainly never knew that her medical school earned the nickname Dead Med thanks to the tragic history of students overdosing on illegal drugs. But Heather would never consider doing anything like that. That is, until her longtime boyfriend dumps her, she finds herself failing anatomy, and her world starts to crumble.

Lowen Ashleigh is a struggling writer on the brink of financial ruin when she accepts the job offer of a lifetime. Jeremy Crawford, husband of best-selling author Verity Crawford, has hired Lowen to complete the remaining books in a successful series his injured wife is unable to finish. Lowen arrives at the Crawford home, ready to sort through years of Verity's notes and outlines, hoping to find enough material to get her started. What Lowen doesn't expect to uncover in the chaotic office is an unfinished autobiography Verity never intended for anyone to read.

Cassie thinks she has met the perfect man. Joel is sweet, handsome, romantic, and best of all, he’s crazy about Cassie. She thinks she’s found the guy she’ll spend the rest of her life with. Have children with. Grow old with. Yes, she knows about his perfect ex-girlfriend, Francesca. The beautiful, brilliant chef, beloved by all his friends. But she thinks Francesca is out of the picture. She thinks Francesca is gone for good. Think again, Cassie.

Jenny sits in the same seat on the same train every week, seeing familiar faces come and go. Until a chance encounter shatters her world. Sixteen years ago, Jenny survived a traumatic ordeal that left her best friend, Susie, missing and presumed dead. The world has its theories about what happened to Susie Patterson, and one of those theories points the finger at Jenny. Now she lives a quiet life, volunteering at a crisis helpline while trying to deal with her own anxiety and the true crime fans obsessed with finding her missing friend.

Jazz Bashara is a criminal. Well, sort of. Life on Artemis, the first and only city on the moon, is tough if you're not a rich tourist or an eccentric billionaire. So smuggling in the occasional harmless bit of contraband barely counts, right? Not when you've got debts to pay and your job as a porter barely covers the rent. Everything changes when Jazz sees the chance to commit the perfect crime, with a reward too lucrative to turn down.

They were madly in love. The perfect couple. That was the story everyone in South River believed...until Gin Talcott and Adam Archer are found shot in their bed. Adam is dead at the scene. Gin is fighting for her life. Detectives Greta Jessup and Finn Pate are assigned to the case. Greta has a long history with Gin’s first husband, Eddie, and is determined to protect his 18-year-old twins. Piper discovered the bodies. Daniel is missing—and so is Adam’s gun.

Sloan will go through hell and back for those she loves. And she does so, every single day. Caught up with the alluring Asa Jackson, a notorious drug trafficker, Sloan has finally found a lifeline to cling to, even if it’s meant compromising her morals. She was in dire straits trying to pay for her brother’s care until she met Asa. But as Sloan became emotionally and economically reliant on him, he in turn developed a disturbing obsession with her—one that becomes increasingly dangerous every day.

Tess Strebel can’t recognize her own face. She can’t recognize her home. Her bedroom is unfamiliar. And she can’t remember the handsome stranger lying next to her in bed. A stranger who claims he’s her husband. Tess reads a letter in her own handwriting, composed during a rare lucid day, explaining her life as it now exists: she was in a terrible car accident one year ago. Every morning, she wakes up unable to remember most of the last decade. Including her own wedding.