Epigenetics is the science of living DNA, charting the chemical pathways that spur DNA into action by turning genes on and off. While the Human Genome Project of the early 2000s was hailed as the key to understanding human heredity and disease, that historic effort was just the beginning. It has taken epigenetics to fill in the picture, explaining how the fixed code of our genome is implemented in countless living processes.

The ancient Greek philosopher Aristotle called man a political animal. But what did he mean by that? What is democracy? How do democracies differ from one another? How do they stack up against their alternatives, like dictatorship? And can democracy survive the many challenges it faces today? To answer these questions, look no further than Democracy and Its Alternatives. Political science, history, and current affairs rolled into one, these 24 lectures investigate democratic government in theory and practice.

As an award-winning host of NPR’s All Things Considered, Ari Shapiro knows the power of storytelling better than most. And the longer he’s worked in the field, the more convinced he’s become of storytelling’s primal importance. In 12 fascinating lessons, this master of the craft reveals the storytelling secrets he’s learned over the course of his career as a reporter and performer, from finding a good story and choosing the right characters to conducting interviews and even delivering a story effectively out loud.

10 interview-based episodes that take ancient designs and applies them to modern lives. Your expert is Prince EA, an artist and inspirational speaker who’s spent the greater part of his career thinking about the ancient world.

Though it ended five centuries ago, the medieval era continues to permeate our world in far-reaching ways. Whether we pay attention to them or not, the influences and imprints of the Middle Ages are all around us, sometimes evident and sometimes less so. In these 36 revealing lectures, you’ll learn how to recognize the medieval impacts on the modern world, and to grasp their significance and implications. The Medieval Legacy offers you a deep look at a stunning millennium of change and innovation which continues to inform our contemporary world.

Imagine a Museum of Lost Art. If this imaginary museum contained just the artwork we knew was lost— whether from theft, purposeful destruction, vandalism, war, or the forces of nature—it would still contain more masterpieces than those in all the world’s current museums combined. Imagine that! In Lost Art: The Stories of Missing Masterpieces, art historian Noah Charney guides you through just such an imaginary museum. In 12 fascinating lectures, you will hear the stories behind the theft and/or destruction of some of the world’s most famous pieces of art.

Great powers no longer fight great wars. But how exactly did countries like the United States go from confronting powerful adversaries in 1914 and 1939 Europe to waging lengthy counterinsurgency campaigns in places like Iraq and Afghanistan? The answer lies in the profound geopolitical and technological changes that came in between.

The history of the Constitution is therefore a history of ideas that define our country and our national identity—and it’s a fascinating and revealing story. The US Constitution Through History gives you the opportunity to explore the story of this powerful document, as well as the way our interpretation of it has evolved. In 24 riveting lectures, Professor Eric Berger of the University of Nebraska takes you on a journey through America’s constitutional history. He takes you inside the minds of the Framers and unpacks the ideas that led to the break from England.

What explains the brain-body connection? How is it that something intangible like stress can really kill? How about the fact that we can and often do worry ourselves sick? And how can we take advantage of the mind’s connection to the body to reduce pain, boost physical performance, and even treat disease? Answer these questions and more in The Power of Mind over Body, a 12-lecture course that will change the way you think about physical health and the brain.

In Understanding Cognitive Biases, you will learn how to recognize biases for what they are, counteract them when necessary, and even use them to your advantage in some instances. In 24 fascinating lectures, Dr. Alexander B. Swan uses examples from psychology experiments, history, politics, movies, TV, comics, social media, and more to illustrate dozens of cognitive biases that affect us all.

In Tibet: History, Culture, and Religion, Professor Constance Kassor, will show you the real, multi-dimensional Tibet and its people who live on the “Roof of the World,” the highest and largest plateau on Earth. In 24 fascinating lectures, you will learn how Tibet’s history was shaped by kings and kingdoms, power struggles, religion, traditions, wars, peace, and the lifestyles that developed in response to living on the world’s highest plateau.

Shedding light on what creative people do, and how they do it, neuroscientists are mapping the regions of the brain that come into play during creative work, showing that creativity is a skill and something that all of us can cultivate. In these 24 compelling lectures, Professor Viskontas takes you on a deep dive into the human creative faculty. Through the many areas of knowledge within the course, Creativity and Your Brain offers empowering and inspiring guidelines for developing your own creativity.

The John F. Kennedy presidency has an indelible hold on our imaginations. Even more than half a century later, we remain captivated by the charismatic young leader who promised us the moon, who remained steadfast in the face of nuclear catastrophe, who told us to “ask not what your country can do for you, but what you can do for your country”—and whose life was cut short by shocking assassination.

Science has come a long way in solving the mysteries of the human brain, but we still have a long way to go. Understanding Disorders of the Brain is a powerful introduction to the journey of brain science in the 21st century and an excellent addition to your lifelong learning library.

Propaganda and Persuasion gives you a one-of-a-kind opportunity to explore the powerful, fascinating, and at times dangerous world of influence. Taught by Professor Dannagal G. Young of the University of Delaware, these 12 eye-opening lectures arm you with the tools of effective communication and the insight to understand—and perhaps resist—persuasion in all its forms.

How the Earth Works takes you on an astonishing journey through time and space. In 48 lectures, you will look at what went into making our planet - from the big bang, to the formation of the solar system, to the subsequent evolution of Earth.

Chemistry and Our Universe: How It All Works is your in-depth introduction to this vital field, taught through 60 engaging half-hour lectures that are suitable for any background or none at all. Covering a year’s worth of introductory general chemistry at the college level, plus intriguing topics that are rarely discussed in the classroom, this amazingly comprehensive course requires nothing more advanced than high-school math. Your guide is Professor Ron B. Davis, Jr., a research chemist and award-winning teacher at Georgetown University.

We are in the midst of a global mental health crisis, and mental illnesses are on the rise. But what causes mental illness? And why are mental health problems so hard to treat? Drawing on decades of research, Harvard psychiatrist Dr. Chris Palmer outlines a revolutionary new understanding that for the first time unites our existing knowledge about mental illness within a single framework: mental disorders are metabolic disorders of the brain. Brain Energy will transform the field of mental health, and the lives of countless people around the world.

Hilarious, fascinating, and a roller coaster of dizzying, historical what-ifs, Napoleon's Hemorrhoids is a potpourri for serious historians and casual history buffs. In one of Phil Mason's many revelations, you'll learn that Communist jets were two minutes away from opening fire on American planes during the Cuban missile crisis, when they had to turn back as they were running out of fuel. You'll discover that before the Battle of Waterloo, Napoleon's painful hemorrhoids prevented him from mounting his horse to survey the battlefield.

Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.

Welcome to the Universe is a personal guided tour of the cosmos by three of today's leading astrophysicists. Inspired by the enormously popular introductory astronomy course that Neil deGrasse Tyson, Michael A. Strauss, and J. Richard Gott taught together at Princeton, this book covers it all - from planets, stars, and galaxies to black holes, wormholes, and time travel.

Astrophysicist Neil deGrasse Tyson has attracted one of the world’s largest online followings with his fascinating, widely accessible insights into science and our universe. Now, Tyson invites us to go behind the scenes of his public fame by unveiling his candid correspondence with people across the globe who have sought him out in search of answers. In this hand-picked collection of 100 letters, Tyson draws upon cosmic perspectives to address a vast array of questions about science, faith, philosophy, life, and of course, Pluto.

How do today's most successful tech companies - Amazon, Google, Facebook, Netflix, Tesla - design, develop, and deploy the products that have earned the love of literally billions of people around the world? Perhaps surprisingly, they do it very differently from the vast majority of tech companies. In Inspired, technology product management thought leader Marty Cagan provides listeners with a master class in how to structure and staff a vibrant and successful product organization and how to discover and deliver technology products that your customers will love.

Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

The real stories behind the scenery of America’s national parks. For 12 years, Andrea Lankford lived in the biggest, most impressive national parks in the world, working a job she loved. She chaperoned baby sea turtles on their journey to sea. She pursued bad guys on her galloping patrol horse. She jumped into rescue helicopters bound for the heart of the Grand Canyon. She won arguments with bears. She slept with a few too many rattlesnakes. Hell yeah, it was the best job in the world! Fortunately, Andrea survived it.

Epigenetics is the science of living DNA, charting the chemical pathways that spur DNA into action by turning genes on and off. While the Human Genome Project of the early 2000s was hailed as the key to understanding human heredity and disease, that historic effort was just the beginning. It has taken epigenetics to fill in the picture, explaining how the fixed code of our genome is implemented in countless living processes.

The Middle Ages was a time of major historical shifts and transformations. This amazing era reverberates with discoveries, innovations, events, and historical processes that are integral to the world we know now. In these 24 enthralling lectures, Professor Salisbury leads you on a sumptuous tour of this incredible historical epoch, making clear that the remarkable historical currents and advances of the Middle Ages unfolded not only in the West, but across the globe, from Europe, Africa, and the Middle East to Asia, the Americas, and beyond.

In The Black Death: New Lessons from Recent Research, celebrated medievalist Dorsey Armstrong shares the fascinating new story of this old pandemic—revealed by dedicated researchers working with 21st-century technologies and a knowledge of language and history that now provide input from all geographic areas of the medieval world. In seven engaging lectures, Professor Armstrong corrects explanations of the pandemic that are now known to be inaccurate and offers a more robust description of plague biology than has ever been known.

The landscape of cancer treatment and prevention is a vastly different place than it was even a decade ago. Thanks to a relatively new focus on molecular medicine, researchers are gaining a deeper understanding of the mechanisms involved in the disease, poising them on the brink of huge breakthroughs. What Science Knows About Cancer reports from the front lines of the war on cancer with a clear and scientifically precise - yet thoroughly accessible - guide to how the disease develops, thrives, and can potentially be conquered.

The ancient Greek philosopher Aristotle called man a political animal. But what did he mean by that? What is democracy? How do democracies differ from one another? How do they stack up against their alternatives, like dictatorship? And can democracy survive the many challenges it faces today? To answer these questions, look no further than Democracy and Its Alternatives. Political science, history, and current affairs rolled into one, these 24 lectures investigate democratic government in theory and practice.

In Understanding Your Inner Genius, presenter Laura Helmuth reveals the latest scientific thinking on genius and intelligence - from the making of a genius, to the increase of worldwide IQ scores, and the mysteries of acquired savantism. With Dr. Helmuth as your guide, you’ll explore the groundbreaking work conducted by distinguished psychologists, psychiatrists, neuroscientists, and educators. With myth-busting exhilaration and more than a bit of controversy, scientific studies point the way to increasing the intellect.

Recent years have seen the introduction of concepts from the new and exciting field of complexity science that have captivated the attention of economists, sociologists, engineers, businesspeople, and many others. These include tipping points, the wisdom of crowds, six degrees of separation (or Kevin Bacon), and emergence. Complexity science can shed light on why businesses or economies succeed and fail, how epidemics spread and can be stopped, and what causes ecological systems to rebalance themselves after a disaster.

Your nervous system is you. All the thoughts, perceptions, moods, passions, and dreams that make you an active, sentient being are the work of this amazing network of cells. For many centuries, people knew this was true. But no one was sure how it happened. Now, thanks to the exciting new field of neuroscience, we can chart the workings of the brain and the rest of the nervous system in remarkable detail to explain how neurons, synapses, neurotransmitters, and other biological processes produce all the experiences of everyday life, in every stage of life.

A relatively recent addition to more traditional law school topics like torts and contracts, legislation and regulation have become more and more of a mainstay in some of the country’s top law schools. Over the course of 12 nuanced and balanced lectures, examine a host of topics including the nature of regulation, the merits of lawmaking by legislation, the challenge of interpreting statutes, and the role of federal agencies in our legal system.

In The Vietnam War, you will learn about the causes and consequences of the war in Vietnam. You will explore the scope of American intervention from air campaigns to large-scale military operations on the ground. You will survey the history of Vietnam from colonial Indochina onward, getting to know the homegrown ideas, personalities, and politics that would come to shape the conflict. You will reconstruct major military operations like the Tet Offensive and Rolling Thunder.

Heidi Sormaz has a PhD in psychology from Yale University with an emphasis on cognitive psychology, and she’s been a meditation and yoga practitioner and teacher for two decades. She is also a reformed over-thinker, so, she knows exactly what you’re going through—or what you’re (over)thinking, so to speak. Over the 12 engaging lessons of Overcome Your Overthinking, Heidi not only provides the science behind cognitive behavioral therapy but she’ll also arm you with a toolbox of exercises and techniques that are most effective at breaking the spell of overthinking.

Charles Darwin's theory of organic evolution-the idea that life on earth is the product of purely natural causes, not the hand of God-set off shock waves that continue to reverberate through Western society, and especially the United States. What makes evolution such a profoundly provocative concept, so convincing to most scientists, yet so socially and politically divisive? These 12 eye-opening lectures are an examination of the varied elements that so often make this science the object of strong sentiments and heated debate.

Thought experiments are “what if” scenarios that invite us to look carefully at how we think and view the world. They’ve been used throughout history by philosophers and other thinkers to explore our intuitions and ways of reasoning, to find solutions to problems, and to expand our knowledge of ourselves and the world. In these 24 eye-opening lectures, Professor Breyer takes you deeply into the historical tradition of thought experiments, shining a light on both the purpose and the outcomes of these compelling mental voyages.

Propaganda and Persuasion gives you a one-of-a-kind opportunity to explore the powerful, fascinating, and at times dangerous world of influence. Taught by Professor Dannagal G. Young of the University of Delaware, these 12 eye-opening lectures arm you with the tools of effective communication and the insight to understand—and perhaps resist—persuasion in all its forms.

Economic forces are everywhere around you. But that doesn't mean you need to passively accept whatever outcome those forces might press upon you. Instead, with these 12 fast-moving and crystal clear lectures, you can learn how to use a small handful of basic nuts-and-bolts principles to turn those same forces to your own advantage.