Epigenetics is the science of living DNA, charting the chemical pathways that spur DNA into action by turning genes on and off. While the Human Genome Project of the early 2000s was hailed as the key to understanding human heredity and disease, that historic effort was just the beginning. It has taken epigenetics to fill in the picture, explaining how the fixed code of our genome is implemented in countless living processes.

The ancient Greek philosopher Aristotle called man a political animal. But what did he mean by that? What is democracy? How do democracies differ from one another? How do they stack up against their alternatives, like dictatorship? And can democracy survive the many challenges it faces today? To answer these questions, look no further than Democracy and Its Alternatives. Political science, history, and current affairs rolled into one, these 24 lectures investigate democratic government in theory and practice.

As an award-winning host of NPR’s All Things Considered, Ari Shapiro knows the power of storytelling better than most. And the longer he’s worked in the field, the more convinced he’s become of storytelling’s primal importance. In 12 fascinating lessons, this master of the craft reveals the storytelling secrets he’s learned over the course of his career as a reporter and performer, from finding a good story and choosing the right characters to conducting interviews and even delivering a story effectively out loud.

10 interview-based episodes that take ancient designs and applies them to modern lives. Your expert is Prince EA, an artist and inspirational speaker who’s spent the greater part of his career thinking about the ancient world.

Though it ended five centuries ago, the medieval era continues to permeate our world in far-reaching ways. Whether we pay attention to them or not, the influences and imprints of the Middle Ages are all around us, sometimes evident and sometimes less so. In these 36 revealing lectures, you’ll learn how to recognize the medieval impacts on the modern world, and to grasp their significance and implications. The Medieval Legacy offers you a deep look at a stunning millennium of change and innovation which continues to inform our contemporary world.

Imagine a Museum of Lost Art. If this imaginary museum contained just the artwork we knew was lost— whether from theft, purposeful destruction, vandalism, war, or the forces of nature—it would still contain more masterpieces than those in all the world’s current museums combined. Imagine that! In Lost Art: The Stories of Missing Masterpieces, art historian Noah Charney guides you through just such an imaginary museum. In 12 fascinating lectures, you will hear the stories behind the theft and/or destruction of some of the world’s most famous pieces of art.

Great powers no longer fight great wars. But how exactly did countries like the United States go from confronting powerful adversaries in 1914 and 1939 Europe to waging lengthy counterinsurgency campaigns in places like Iraq and Afghanistan? The answer lies in the profound geopolitical and technological changes that came in between.

The history of the Constitution is therefore a history of ideas that define our country and our national identity—and it’s a fascinating and revealing story. The US Constitution Through History gives you the opportunity to explore the story of this powerful document, as well as the way our interpretation of it has evolved. In 24 riveting lectures, Professor Eric Berger of the University of Nebraska takes you on a journey through America’s constitutional history. He takes you inside the minds of the Framers and unpacks the ideas that led to the break from England.

What explains the brain-body connection? How is it that something intangible like stress can really kill? How about the fact that we can and often do worry ourselves sick? And how can we take advantage of the mind’s connection to the body to reduce pain, boost physical performance, and even treat disease? Answer these questions and more in The Power of Mind over Body, a 12-lecture course that will change the way you think about physical health and the brain.

In Understanding Cognitive Biases, you will learn how to recognize biases for what they are, counteract them when necessary, and even use them to your advantage in some instances. In 24 fascinating lectures, Dr. Alexander B. Swan uses examples from psychology experiments, history, politics, movies, TV, comics, social media, and more to illustrate dozens of cognitive biases that affect us all.

In Tibet: History, Culture, and Religion, Professor Constance Kassor, will show you the real, multi-dimensional Tibet and its people who live on the “Roof of the World,” the highest and largest plateau on Earth. In 24 fascinating lectures, you will learn how Tibet’s history was shaped by kings and kingdoms, power struggles, religion, traditions, wars, peace, and the lifestyles that developed in response to living on the world’s highest plateau.

Shedding light on what creative people do, and how they do it, neuroscientists are mapping the regions of the brain that come into play during creative work, showing that creativity is a skill and something that all of us can cultivate. In these 24 compelling lectures, Professor Viskontas takes you on a deep dive into the human creative faculty. Through the many areas of knowledge within the course, Creativity and Your Brain offers empowering and inspiring guidelines for developing your own creativity.

The John F. Kennedy presidency has an indelible hold on our imaginations. Even more than half a century later, we remain captivated by the charismatic young leader who promised us the moon, who remained steadfast in the face of nuclear catastrophe, who told us to “ask not what your country can do for you, but what you can do for your country”—and whose life was cut short by shocking assassination.

Science has come a long way in solving the mysteries of the human brain, but we still have a long way to go. Understanding Disorders of the Brain is a powerful introduction to the journey of brain science in the 21st century and an excellent addition to your lifelong learning library.

Propaganda and Persuasion gives you a one-of-a-kind opportunity to explore the powerful, fascinating, and at times dangerous world of influence. Taught by Professor Dannagal G. Young of the University of Delaware, these 12 eye-opening lectures arm you with the tools of effective communication and the insight to understand—and perhaps resist—persuasion in all its forms.

My Big TOE: Awakening, written by a nuclear physicist in the language of contemporary culture, unifies science and philosophy, physics and metaphysics, mind and matter, purpose and meaning, the normal and the paranormal. The entirety of human experience (mind, body, and spirit) including both our objective and subjective worlds is brought together under one seamless scientific understanding.

Chemistry and Our Universe: How It All Works is your in-depth introduction to this vital field, taught through 60 engaging half-hour lectures that are suitable for any background or none at all. Covering a year’s worth of introductory general chemistry at the college level, plus intriguing topics that are rarely discussed in the classroom, this amazingly comprehensive course requires nothing more advanced than high-school math. Your guide is Professor Ron B. Davis, Jr., a research chemist and award-winning teacher at Georgetown University.

Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.

How the Earth Works takes you on an astonishing journey through time and space. In 48 lectures, you will look at what went into making our planet - from the big bang, to the formation of the solar system, to the subsequent evolution of Earth.

We are in the midst of a global mental health crisis, and mental illnesses are on the rise. But what causes mental illness? And why are mental health problems so hard to treat? Drawing on decades of research, Harvard psychiatrist Dr. Chris Palmer outlines a revolutionary new understanding that for the first time unites our existing knowledge about mental illness within a single framework: mental disorders are metabolic disorders of the brain. Brain Energy will transform the field of mental health, and the lives of countless people around the world.

Astrophysicist Neil deGrasse Tyson has attracted one of the world’s largest online followings with his fascinating, widely accessible insights into science and our universe. Now, Tyson invites us to go behind the scenes of his public fame by unveiling his candid correspondence with people across the globe who have sought him out in search of answers. In this hand-picked collection of 100 letters, Tyson draws upon cosmic perspectives to address a vast array of questions about science, faith, philosophy, life, and of course, Pluto.

Hilarious, fascinating, and a roller coaster of dizzying, historical what-ifs, Napoleon's Hemorrhoids is a potpourri for serious historians and casual history buffs. In one of Phil Mason's many revelations, you'll learn that Communist jets were two minutes away from opening fire on American planes during the Cuban missile crisis, when they had to turn back as they were running out of fuel. You'll discover that before the Battle of Waterloo, Napoleon's painful hemorrhoids prevented him from mounting his horse to survey the battlefield.

Dr. Catherine Kleier invites us to open our eyes to the phenomenal world of plant life and to the process she calls “Natura Revelata”, the joy of celebrating and learning from the secrets of nature. As Dr. Kleier shares her knowledge with contagious excitement for her subject, she emphasizes the middle ground: Instead of focusing on cell microbiology or the study of ecosystems and habitats, she stresses the basic biology, function, and the amazing adaptations of the plants we see all around us.

In this illuminating audiobook, Tyson and coauthor James Trefil, a renowned physicist and science popularizer, take on the big questions that humanity has been posing for millennia - How did life begin? What is our place in the universe? Are we alone? - and provide answers based on the most current data, observations, and theories.

At the end of his career, Albert Einstein was pursuing a dream far more ambitious than the theory of relativity. He was trying to find an equation that explained all physical reality - a theory of everything. Experimental physicist and award-winning educator Dr. Don Lincoln takes you on this exciting journey in The Theory of Everything: The Quest to Explain All Reality. Suitable for the intellectually curious at all levels and assuming no background beyond basic high-school math, these 24 half-hour lectures cover recent developments at the forefront of particle physics and cosmology.

Epigenetics is the science of living DNA, charting the chemical pathways that spur DNA into action by turning genes on and off. While the Human Genome Project of the early 2000s was hailed as the key to understanding human heredity and disease, that historic effort was just the beginning. It has taken epigenetics to fill in the picture, explaining how the fixed code of our genome is implemented in countless living processes.

Science has come a long way in solving the mysteries of the human brain, but we still have a long way to go. Understanding Disorders of the Brain is a powerful introduction to the journey of brain science in the 21st century and an excellent addition to your lifelong learning library.

Thought experiments are “what if” scenarios that invite us to look carefully at how we think and view the world. They’ve been used throughout history by philosophers and other thinkers to explore our intuitions and ways of reasoning, to find solutions to problems, and to expand our knowledge of ourselves and the world. In these 24 eye-opening lectures, Professor Breyer takes you deeply into the historical tradition of thought experiments, shining a light on both the purpose and the outcomes of these compelling mental voyages.

Propaganda and Persuasion gives you a one-of-a-kind opportunity to explore the powerful, fascinating, and at times dangerous world of influence. Taught by Professor Dannagal G. Young of the University of Delaware, these 12 eye-opening lectures arm you with the tools of effective communication and the insight to understand—and perhaps resist—persuasion in all its forms.

The Middle Ages was a time of major historical shifts and transformations. This amazing era reverberates with discoveries, innovations, events, and historical processes that are integral to the world we know now. In these 24 enthralling lectures, Professor Salisbury leads you on a sumptuous tour of this incredible historical epoch, making clear that the remarkable historical currents and advances of the Middle Ages unfolded not only in the West, but across the globe, from Europe, Africa, and the Middle East to Asia, the Americas, and beyond.

The ancient Greek philosopher Aristotle called man a political animal. But what did he mean by that? What is democracy? How do democracies differ from one another? How do they stack up against their alternatives, like dictatorship? And can democracy survive the many challenges it faces today? To answer these questions, look no further than Democracy and Its Alternatives. Political science, history, and current affairs rolled into one, these 24 lectures investigate democratic government in theory and practice.

As the birthplace of Judaism and Christianity, the Holy Land (in and around modern-day Israel) is one of the most important regions in the world and the setting for defining events in religious history. Comb through this evidence for yourself with The Holy Land Revealed, which will add new dimensions to your understanding of this dynamic place. Delivered by archaeologist and award-winning Professor Jodi Magness of The University of North Carolina at Chapel Hill, these 36 lectures give you an insider’s look at how archaeology helps us relive this period of civilization.

What explains the brain-body connection? How is it that something intangible like stress can really kill? How about the fact that we can and often do worry ourselves sick? And how can we take advantage of the mind’s connection to the body to reduce pain, boost physical performance, and even treat disease? Answer these questions and more in The Power of Mind over Body, a 12-lecture course that will change the way you think about physical health and the brain.

Creation stories, found within many ancient cultures, are traditional accounts of the origins of the universe, the earth, and humanity. Often embodied as epic poetry, and told through the acts of divine beings, creation stories illuminate the values, beliefs, and creeds of the earliest civilizations. As such, these stories show us how early cultures made sense of the human condition, in theological, philosophical, and political terms. These 12 dynamic and thought-provoking lectures offer you a penetrating look at the origin stories of the great civilizations of the Mediterranean.

The issues addressed by macroeconomics are all around you, all the time—from taxes to inflation to mention of the GDP on the nightly news. By learning the principles of macroeconomics, you’ll be able to go beyond simply hearing the terms to better understanding their relationships to each other and how they create the economic environment in which you live. In fact, macroeconomics with its “big-picture glasses” allows you to better ask—and better try to answer—the biggest questions of our time, questions that impact the lives of billions of people.

Nothing has had a more profound impact on the development of modern civilization than thermodynamics. Thermodynamic processes are at the heart of everything that involves heat, energy, and work, making an understanding of the subject indispensable for careers in engineering, physical science, biology, meteorology, and even nutrition and culinary arts. Get an in-depth tour of this vital and fascinating science in 24 enthralling lectures suitable for everyone from science novices to experts who wish to review elementary concepts and formulas.

In Understanding Cognitive Biases, you will learn how to recognize biases for what they are, counteract them when necessary, and even use them to your advantage in some instances. In 24 fascinating lectures, Dr. Alexander B. Swan uses examples from psychology experiments, history, politics, movies, TV, comics, social media, and more to illustrate dozens of cognitive biases that affect us all.

In The Black Death: New Lessons from Recent Research, celebrated medievalist Dorsey Armstrong shares the fascinating new story of this old pandemic—revealed by dedicated researchers working with 21st-century technologies and a knowledge of language and history that now provide input from all geographic areas of the medieval world. In seven engaging lectures, Professor Armstrong corrects explanations of the pandemic that are now known to be inaccurate and offers a more robust description of plague biology than has ever been known.

The landscape of cancer treatment and prevention is a vastly different place than it was even a decade ago. Thanks to a relatively new focus on molecular medicine, researchers are gaining a deeper understanding of the mechanisms involved in the disease, poising them on the brink of huge breakthroughs. What Science Knows About Cancer reports from the front lines of the war on cancer with a clear and scientifically precise - yet thoroughly accessible - guide to how the disease develops, thrives, and can potentially be conquered.

Join Professor Horton for an accessible introduction from contract essentials, including offers, acceptances, counteroffers, and options and defenses, to contract enforcement, such as fraud, duress, and unconscionability. In lectures that demystify concepts and terms that can often seem intimidating to individuals outside of legal fields, you’ll better understand (and navigate) the contracts of everyday life.