
From Breakthrough to Blockbuster
The Business of Biotechnology
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Narrated by:
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Chris Andrew Ciulla
About this listen
Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources.
Biotech companies have met the challenge by creating nearly 40% more of the most important treatments for previously unmet medical needs. Moreover, they have done so with much lower overall costs.
From Breakthrough to Blockbuster focuses on both the companies themselves and the broader biotech ecosystem that supports them. It paints a portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies, demonstrating how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions.
©2022 Oxford University Press (P)2022 Ascent AudioListeners also enjoyed...
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-
-
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For Blood and Money
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- Narrated by: Rob Shapiro
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- Unabridged
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Overall
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Performance
-
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For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.
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Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing - atom by atom - both a new life-saving immunosuppressant drug and a drug to combat the virus that causes AIDS.
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You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door. So what, exactly, is your immune system? In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defenses.
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-
Steve Taylor for the win
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The Song of the Cell
- An Exploration of Medicine and the New Human
- By: Siddhartha Mukherjee
- Narrated by: Dennis Boutsikaris
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Overall
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Performance
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Story
From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.
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Overall
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In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex's bold endurance and eventual success.
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For me this was not interesting
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By: Barry Werth
What listeners say about From Breakthrough to Blockbuster
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Fox2
- 11-12-22
Excellent description of the biotech industry
Fantastic book describing the biotech industry from its beginning to now. Engaging and recommended to read or listen.
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- Momo Abbasi
- 04-28-24
Wonderful book!
If you want to understand the biotech industry you MUST READ this! Comprehensive and easy to follow.
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- Anonymous User
- 09-12-23
Nothing to learn for pharma professionals
Nice introduction to the world of pharma R&D, but those who’ve been in the business have probably heard the stories many times already.
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