
The Billion Dollar Molecule
One Company's Quest for the Perfect Drug
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Narrated by:
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Stephen Bowlby
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By:
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Barry Werth
About this listen
Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research.
Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing - atom by atom - both a new life-saving immunosuppressant drug and a drug to combat the virus that causes AIDS.
You will be hooked from start to finish, as you go from the labs, where obsessive, fiercely competitive scientists struggle for a breakthrough, to Wall Street, where the wheeling and dealing takes on a life of its own, as Boger courts investors and finally decides to take Vertex public. Here is a fascinating, no-holds-barred account of the business of science that includes an updated epilogue about the most recent developments in the quest for a drug to cure AIDS.
©1994 Barry Werth; Introduction copyright 2014 by Barry Werth (P)2021 TantorListeners also enjoyed...
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- By Billy on 07-21-14
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Just Six Numbers
- The Deep Forces That Shape the Universe
- By: Martin J. Rees
- Narrated by: John Curless
- Length: 6 hrs and 44 mins
- Unabridged
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There are deep connections between stars and atoms, between the cosmos and the microworld. Just six numbers, imprinted in the "Big Bang", determine the essential features of our entire physical world. Moreover, cosmic evolution is astonishingly sensitive to the values of these numbers. If any one of them were "untuned", there could be no stars and no life. This realization offers a radically new perspective on our universe, our place in it, and the nature of physical laws.
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Old Fine-Tuning Book
- By Michael on 12-16-18
By: Martin J. Rees
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Human Errors
- A Panorama of Our Glitches, from Pointless Bones to Broken Genes
- By: Nathan H. Lents
- Narrated by: L.J. Ganser
- Length: 7 hrs and 54 mins
- Unabridged
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We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.
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From Pointless Bones to Broken Genes to...Aliens?
- By Katy.LED on 12-04-18
By: Nathan H. Lents
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- By: Thomas Hager
- Narrated by: Angelo Di Loreto
- Length: 8 hrs and 39 mins
- Unabridged
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Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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Engrossing to physicians & lay persons alike
- By C. White on 03-08-19
By: Thomas Hager
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Consciousness and the Brain
- Deciphering How the Brain Codes Our Thoughts
- By: Stanislas Dehaene
- Narrated by: David Drummond
- Length: 11 hrs and 17 mins
- Unabridged
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How does the brain generate a conscious thought? And why does so much of our knowledge remain unconscious? Thanks to clever psychological and brain-imaging experiments, scientists are closer to cracking this mystery than ever before. In this lively book, Stanislas Dehaene describes the pioneering work his lab and the labs of other cognitive neuroscientists worldwide have accomplished in defining, testing, and explaining the brain events behind a conscious state.
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I had no idea we knew this much.
- By Tristan on 01-18-16
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Restricted Data
- The History of Nuclear Secrecy in the United States
- By: Alex Wellerstein
- Narrated by: John McLain
- Length: 17 hrs and 24 mins
- Unabridged
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Drawing on troves of declassified files, including records released by the government for the first time through the author's efforts, Restricted Data traces the complex evolution of the US nuclear secrecy regime from the first whisper of the atomic bomb through the mounting tensions of the Cold War and into the early 21st century. A compelling history of powerful ideas at war, it tells a story that feels distinctly American: rich, sprawling, and built on the conflict between high-minded idealism and ugly, fearful power.
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Alright. Some interesting facts
- By Dustin C. on 07-28-24
By: Alex Wellerstein
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The Catalyst
- RNA and the Quest to Unlock Life's Deepest Secrets
- By: Thomas R. Cech
- Narrated by: Joshua Saxon
- Length: 6 hrs and 54 mins
- Unabridged
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A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.
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Captivating
- By Auinash Kalsotra on 09-16-24
By: Thomas R. Cech
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Superconvergence
- How the Genetics, Biotech, and AI Revolutions Will Transform our Lives, Work, and World
- By: Jamie Metzl
- Narrated by: James Anderson Foster, Jamie Metzl
- Length: 15 hrs and 44 mins
- Unabridged
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Leading futurist and OneShared.World founder Jamie Metzl explores how genome sequencing, gene editing, artificial intelligence, and other technologies are not only changing our lives, but catalyzing each other in radical and accelerating ways. These technologies have the potential to improve our health, feed billions of people, supercharge our economies, and store essential information for millions of years, but can also—if we are not careful—do immeasurable harm.
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Great Book Somewhat Spoiled by Self-Promotion
- By Jack E. Koepke on 06-22-24
By: Jamie Metzl
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Data and Goliath
- The Hidden Battles to Collect Your Data and Control Your World
- By: Bruce Schneier
- Narrated by: Dan John Miller
- Length: 9 hrs and 27 mins
- Unabridged
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In Data and Goliath, Schneier reveals the full extent of surveillance, censorship, and propaganda in society today, examining the risks of cybercrime, cyberterrorism, and cyberwar. He shares technological, legal, and social solutions that can help shape a more equal, private, and secure world. This is an audiobook to which everyone with an Internet connection - or bank account or smart device or car, for that matter - needs to listen.
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Great information
- By Jeremy on 06-12-15
By: Bruce Schneier
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Blood and Guts
- A History of Surgery
- By: Richard Hollingham
- Narrated by: Liam Gerrard
- Length: 8 hrs and 32 mins
- Unabridged
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Today, astonishing surgical breakthroughs are making limb transplants, face transplants, and a host of other previously undreamed-of operations possible. But getting here has not been a simple story of medical progress. In Blood and Guts, veteran science writer Richard Hollingham weaves a compelling narrative from the key moments in surgical history. We have a ringside seat in the operating theater of University College Hospital in London as world-renowned Victorian surgeon Robert Liston performs a remarkable amputation in 30 seconds - from first cut to final stitch.
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I love this book!
- By Kristin on 08-25-19
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An Epidemic of Absence
- A New Way of Understanding Allergies and Autoimmune Diseases
- By: Moises Velasquez-Manoff
- Narrated by: Chris Sorensen
- Length: 17 hrs and 6 mins
- Unabridged
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An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
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The point of view from a Veterinarian immunologist
- By rtgymnast on 11-03-17
Book is interesting but narrator is not
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