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Junk DNA
- A Journey Through the Dark Matter of the Genome
- Narrated by: Cat Gould
- Length: 10 hrs and 16 mins
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Publisher's summary
For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases.
Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word "gene" and have engendered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field.
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Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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In to the abyss we ascend, a scary future
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Herding Hemingway's Cats
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- Narrated by: Kat Arney
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The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work?
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A non-scientists misguided interpretation
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The Gene
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- Length: 19 hrs and 22 mins
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The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.
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It's a Wonderful Book
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The Vital Question
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- Narrated by: Kevin Pariseau
- Length: 11 hrs and 27 mins
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The Earth teems with life: in its oceans, forests, skies, and cities. Yet there's a black hole at the heart of biology. We do not know why complex life is the way it is, or, for that matter, how life first began. In The Vital Question, award-winning author and biochemist Nick Lane radically reframes evolutionary history, putting forward a solution to conundrums that have puzzled generations of scientists.
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Ouch!
- By Mark on 06-24-16
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p53: The Gene That Cracked the Cancer Code
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p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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Excellent story! Unfortunate narration at start
- By Adriana on 12-25-14
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An Epidemic of Absence
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An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
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The point of view from a Veterinarian immunologist
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Missing Microbes
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In Missing Microbes, Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now this invisible eden is being irrevocably damaged by some of our most revered medical advances-antibiotics-threatening the extinction of our irreplaceable microbes with terrible health consequences.
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Very enlightening and information well supported
- By James on 05-03-15
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Sicker, Fatter, Poorer
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Lurking in our homes, hiding in our offices, and polluting the air we breathe is something sinister. Something we’ve turned a blind eye to for far too long. Dr. Leonardo Trasande, a pediatrician, professor, and world-renowned researcher, tells the story of how our everyday surroundings are making us sicker, fatter, and poorer. Through a blend of narrative, scientific detective work, and concrete information about the connections between chemicals and disease, he reveals what we can do to protect ourselves and our families in the short-term, and how we can help bring the change we deserve.
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The Must Read Book of 2019 is here early on Audio!
- By Ryan S on 12-21-18
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The Cancer Chronicles
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When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.
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A quick read - hard to put down
- By Digital Dilema on 09-06-13
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A Series of Fortunate Events
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Why is the world the way it is? How did we get here? Does everything happen for a reason, or are some things left to chance? Philosophers and theologians have pondered these questions for millennia, but startling scientific discoveries over the past half century are revealing that we live in a world driven by chance. A Series of Fortunate Events tells the story of the awesome power of chance and how it is the surprising source of all the beauty and diversity in the living world.
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We are for a short time.
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10% Human
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You are just 10% human. For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony. Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.
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Must read for anyone that wants to be healthy
- By T. Kalinowski on 06-05-21
By: Alanna Collen
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Brilliant! But please update!
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Decent Overview. Could lose sarcasm.
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Really good
- By Talia on 03-25-23
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A Crack in Creation
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-
In to the abyss we ascend, a scary future
- By Philomath on 06-17-17
By: Jennifer A. Doudna, and others
-
Regenesis
- How Synthetic Biology Will Reinvent Nature and Ourselves
- By: George M. Church, Ed Regis
- Narrated by: Peter Lerman
- Length: 10 hrs and 47 mins
- Unabridged
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Brilliant! But please update!
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What listeners say about Junk DNA
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Amazon Customer
- 07-03-20
lamarck: 1 darwin: 0...
the last half century of biology owes an apology
apparently God don't make no junk after all.
this book is a snapshot of the tip of the iceberg from miles away. what a time to be alive
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2 people found this helpful
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- Julia Jones
- 04-20-22
Higher Understanding
You need to have higher education to fully grasp this book. Otherwise, it is a great book!
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1 person found this helpful
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- Sam C.
- 09-21-23
A great update
As a physician, this was a great update about advances in genetics. This was a great detailed basic science update. It had a mixture of many different Concepts mixed with clinical examples.
As with many great books, you can start with the appendix to get you fascinated.
I have a neighbor working in pharmaceuticals who mentioned in passing some of the technologies mentioned and this book helps to connect a lot of dots.
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- Marco
- 05-09-23
Don't bother with the audiobook
This book is a worse version of The Epigenetics Revolution by the same author. It is puzzling to me why a new book, with largely overlapping content and much worse editing, was needed.
The audiobook is particularly bad, no effort has been made into making it easier to follow for those who don't have access to the text. Figures keep being referenced, but no accompanying material was provided (this is perfectly possible, see for example Why We Sleep, which provides an accompanying PDF with all the relevant figures).
So I would stay away from this and instead read/listen to the previous, much better book The Epigenetics Revolution.
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- Christopher
- 02-21-21
perhaps a better textbook than a Saturday read
Nice British presenter, made me feel I was on hold with the bank. For eons.
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4 people found this helpful
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- Bill A
- 04-11-21
What’s the point
They write on dna or protein they insist on spending 20 minutes saying either the dna or protein codons... it’s annoying as hell
STOP
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7 people found this helpful