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The Inheritance
- A Family on the Front Lines of the Battle Against Alzheimer's Disease
- Narrated by: Callie Beaulieu
- Length: 9 hrs and 46 mins
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Publisher's summary
Every 69 seconds, someone is diagnosed with Alzheimer's disease. Of the top 10 killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can.
The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer's, an inherited genetic mutation that causes the disease in 100 percent of cases, and has a 50 percent chance of being passed onto the next generation. Of the six DeMoe children whose father had it, five have inherited the gene; the sixth, Karla, has inherited responsibility for all of them.
But rather than give up in the face of such news, the DeMoes have agreed to spend their abbreviated years as part of a worldwide study that could utterly change the landscape of Alzheimer's research and offers the brightest hope for future treatments - and possibly a cure.
Drawing from several years of in-depth research with this charming and upbeat family, journalist Niki Kapsambelis tells the story of Alzheimer's through the humanizing lens of these ordinary people made extraordinary by both their terrible circumstances and their bravery.
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A Bittersweet Season
- Caring for Our Aging Parents - And Ourselves
- By: Jane Gross
- Narrated by: Kate Reading
- Length: 15 hrs and 35 mins
- Unabridged
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In telling the intimate story of caring for her aged and ailing mother, Jane Gross offers indispensable, and often surprising, advice for the rapidly increasing number of adult children responsible for aging parents. Gross deftly weaves the specifics of her personal experience with a comprehensive resource for effectively managing the lives of one's own parents while keeping sanity and strength intact.
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Exceptional, thought-provoking, liberating!
- By Anne on 08-10-11
By: Jane Gross
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The Birth of the Pill
- How Four Crusaders Reinvented Sex and Launched a Revolution
- By: Jonathan Eig
- Narrated by: Gayle Hendrix
- Length: 12 hrs and 26 mins
- Unabridged
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We know it simply as "the pill", yet its genesis was anything but simple. Jonathan Eig's masterful narrative revolves around four principal characters: the fiery feminist Margaret Sanger, who was a champion of birth control in her campaign for the rights of women but neglected her own children in pursuit of free love; the beautiful Katharine McCormick, who owed her fortune to her wealthy husband, the son of the founder of International Harvester and a schizophrenic.
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Overall Excellent Read
- By Rachel on 04-02-22
By: Jonathan Eig
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Your Heart, My Hands
- An Immigrant's Remarkable Journey to Become One of America's Preeminent Cardiac Surgeons
- By: Arun K. Singh MD, John Hanc - contributor, Delos Cosgrove MD - foreword
- Narrated by: Shridhar Solanki
- Length: 8 hrs and 39 mins
- Unabridged
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Leaving a life marked by crippling setbacks and his father's doubt, in 1967 a 20-something doctor from India arrived in America with only five dollars and the desire to claim his American dream. Faced with an entirely new culture, racism, and the lasting effects of disabling childhood injuries, through hard work and perseverance he overcame all odds. Now having performed over 15,000 open-heart surgeries, more than nearly every surgeon in history, Dr. Singh reflects on his most memorable patients and his incredible personal life.
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Remarkable!
- By Stacey on 12-01-22
By: Arun K. Singh MD, and others
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Brotherhood
- Dharma, Destiny, and the American Dream
- By: Sanjiv Chopra, Deepak Chopra
- Narrated by: Deepak Chopra, Sanjiv Chopra
- Length: 12 hrs and 53 mins
- Unabridged
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The Chopra brothers were among the most eager and ambitious of the new generation. In the 1970s, they each emigrated to the United States to make a new life. Both faced tough obstacles: while Deepak encountered resistance from Western-trained doctors over what he called the mind-body connection, Sanjiv struggled to reconcile the beliefs of his birthplace with those of his new home. Eventually, each brother became convinced that America was the right place to build a life, and the Chopras went on to great achievements.
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How to Toot Your Horn
- By Kenneth on 07-01-13
By: Sanjiv Chopra, and others
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The Neuroscientist Who Lost Her Mind
- My Tale of Madness and Recovery
- By: Barbara K. Lipska, Elaine McArdle - contributor
- Narrated by: Emma Powell
- Length: 6 hrs and 54 mins
- Unabridged
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In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.
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Be Prepared To Feel Insane--
- By Gillian on 04-11-18
By: Barbara K. Lipska, and others
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The Desperate Hours
- One Hospital's Fight to Save a City on the Pandemic's Front Lines
- By: Marie Brenner
- Narrated by: Kirsten Potter
- Length: 15 hrs and 41 mins
- Unabridged
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In the spring of 2020, COVID-19 arrived in New York City. Before long, America’s largest metropolis was at war against a virus that mercilessly swept through its five boroughs. In The Desperate Hours, award-winning journalist Marie Brenner, having been granted unprecedented 18-month access to the entire New York-Presbyterian hospital system, tells the story of the doctors, nurses, residents, researchers, and suppliers who tried to save lives across Manhattan, Queens, and Brooklyn and the northern periphery of the city.
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Way too much politics
- By Josh on 07-18-22
By: Marie Brenner
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Brainstorm
- Detective Stories from the World of Neurology
- By: Suzanne O'Sullivan
- Narrated by: Christine Williams
- Length: 8 hrs and 51 mins
- Unabridged
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Brainstorm follows the stories of people whose medical diagnoses are so strange even their doctor struggles to know how to solve them. A man who sees cartoon characters running across the room; a girl whose world suddenly seems completely distorted, as though she were Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving. The brain is the most complex structure in the universe. Neurologists must puzzle out life-changing diagnoses from the tiniest of clues, the ultimate medical detective work.
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Not As Compelling...
- By Douglas on 11-08-18
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The Boy Who Loved Too Much
- A True Story of Pathological Friendliness
- By: Jennifer Latson
- Narrated by: Heather Auden
- Length: 10 hrs and 20 mins
- Unabridged
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What would it be like to see everyone as a friend? Twelve-year-old Eli D'Angelo has a genetic disorder that obliterates social inhibitions, making him irrepressibly friendly, indiscriminately trusting, and unconditionally loving toward everyone he meets. It also makes him enormously vulnerable. Eli lacks the innate skepticism that will help his peers navigate adolescence more safely - and vastly more successfully.
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Williams Syndrome
- By Sharlotte on 09-20-19
By: Jennifer Latson
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The Attachment Effect
- Exploring the Powerful Ways Our Earliest Bond Shapes Our Relationships and Lives
- By: Peter Lovenheim
- Narrated by: Graham Winton
- Length: 8 hrs and 36 mins
- Unabridged
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Attachment theory is having a moment. Recently covered in the New York Times Magazine, New York magazine, and elsewhere, it's also the subject of popular relationship guides. Why is this 60-year-old theory, widely accepted in psychological circles, suddenly in vogue? Because people are discovering how powerfully it sheds light on who we love - and how. Fascinated by the subject, award-winning journalist and author Peter Lovenheim went on a years-long journey to understand it from the inside out.
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Failed to Attach
- By Danielle SeCheverell on 07-21-20
By: Peter Lovenheim
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Black Man in a White Coat
- A Doctor's Reflections on Race and Medicine
- By: Damon Tweedy M.D.
- Narrated by: Corey Allen
- Length: 8 hrs and 44 mins
- Unabridged
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When Damon Tweedy begins medical school, he envisions a bright future where his segregated, working-class background will become largely irrelevant. Instead, he finds that he has joined a new world where race is front and center. The recipient of a scholarship designed to increase black student enrollment, Tweedy soon meets a professor who bluntly questions whether he belongs in medical school, a moment that crystallizes the challenges he will face throughout his career.
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Absolutely eye opening!
- By Kelene on 02-23-16
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Knocking on Heaven's Door
- The Path to a Better Way of Death
- By: Katy Butler
- Narrated by: Katy Butler
- Length: 10 hrs and 28 mins
- Unabridged
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Like so many of us, award-winning writer Katy Butler always assumed her aging parents would experience healthy, active retirements before dying peacefully at home. Then her father suffered a stroke that left him incapable of easily finishing a sentence or showering without assistance. Her mother was thrust into full-time caregiving, and Katy became one of the 24 million Americans who help care for aging parents. In an effort to correct a minor and non - life threatening heart arrhythmia, doctors outfitted her father with a pacemaker.
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A better way to narrate a book about death?
- By MAUREEN on 10-21-13
By: Katy Butler
What listeners say about The Inheritance
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- kate York
- 02-10-24
Heartbreaking, but informative story
Wonderful mix of a family story and a history of Alzheimer’s research. Hard to listen to the impact of this disease, but gives you perspective on what kind of sacrifice it takes to make REAL medical breakthroughs. A must read/listen for someone interested in Alz research
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- Marirosa Rosado
- 02-26-24
Great research and story intertwined
Great narrator, but should read Spanish words like “paisa” correctly, in Spanish, so they may be recognized by the listener.
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- Julie
- 08-19-17
Captivating for those with a personal connection
I am a family survivor of Alzheimer's disease, a healthcare provider who has dedicated my work to treating people with dementia and educating those who care for them, and now a teacher of others who want to bring hope to a generation facing this awful disease. I found this full of both clinical and personal information that truly cast AD in the prominent light it needs to find a cure.
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- Gillian
- 04-16-17
A Cover-to-Cover Slug in the Gut, but Inspiring
We currently have this devastating illness in the family, so "The Inheritance" hit close to home. My husband has it on both sides of the family, things aren't looking good; how do you live your life with something like that looming on your own horizon?
The book is filled with cutting edge science, very human people suffering yet living with a sense of duty, if not hope. It's an utterly courageous book, from doctors and scientists, to victims and loved ones, from those on the sidelines to those ultimately condemned to a death in the fetal position.
One of the things I liked most about the book is that it shows Alzheimer's as something where there's hope for treatment, something unthinkable earlier on, and something I was totally unaware of. There are studies galore, the stories of brilliant and lucky research, of scientists who fail a million times but who pick themselves up, tweak their thinking, plug in the numbers for that millionth and first (modest) success.
And through it all, are the utterly captivating DeMoes who struggle and hope, who have the courage to live another day in the name of love, hope, and science. You get to know each to them, and it's a heartbreaking listen.
At times tough to listen to but always inspiring, "The Inheritance" is a book I'll be listening to again and again.
It's amazing what you can do if you get just five extra years...
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12 people found this helpful
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- Sheila J.
- 07-15-17
Heart wrenching
This story is heart wrenching for the Demoe families. I grew up in Tioga and knew them.
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1 person found this helpful
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- SaraN
- 04-26-24
Heart breaking
Very good read, difficult to hear about the families loss and inheritance of such a profound Disease.
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