From the celebrated neurobiologist and primatologist, a landmark, genre-defining examination of human behavior, both good and bad, and an answer to the question: Why do we do the things we do? Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: He starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its evolutionary legacy.

Robert Sapolsky’s Behave, his now classic account of why humans do good and why they do bad, pointed toward an unsettling conclusion: We may not grasp the precise marriage of nature and nurture that creates the physics and chemistry at the base of human behavior, but that doesn’t mean it doesn’t exist. Now, in Determined, Sapolsky takes his argument all the way, mounting a brilliant (and in his inimitable way, delightful) full-frontal assault on the pleasant fantasy that there is some separate self telling our biology what to do.

Not only can we not currently explain the origin of the universe, it is questionable we will ever be able to explain it. The notion that there are universes within particles, or that particles are conscious, is ascientific, as is the hypothesis that our universe is a computer simulation. On the other hand, the idea that the universe itself is conscious is difficult to rule out entirely.

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

What does it mean to “be you” - that is, to have a specific, conscious experience of the world around you and yourself within it? There may be no more elusive or fascinating question. Historically, humanity has considered the nature of consciousness to be a primarily spiritual or philosophical inquiry, but scientific research is now mapping out compelling biological theories and explanations for consciousness and selfhood.

In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and more.

A cataclysmic planetary phenomenon is gathering force deep within the Earth. The magnetic North Pole will eventually trade places with the South Pole. Satellite evidence suggests to some scientists that the move has already begun, but most still think it won't happen for many decades. All agree that it has happened many times before and will happen again. But this time it will be different. It will be a very bad day for modern civilization.

The answers to these questions are right behind our eyes. The greatest technology we have ever discovered on our planet is the three-pound organ carried in the vault of the skull. This book is not simply about what the brain is; it is about what it does. The magic of the brain is not found in the parts it’s made of but in the way those parts unceasingly reweave themselves in an electric, living fabric.

Anxiety affects more than forty million Americans—a number that continues to climb in the wake of the COVID-19 pandemic. While conventional medicine tends to view anxiety as a “neck-up” problem—that is, one of brain chemistry and psychology—the truth is that the origins of anxiety are rooted in the body. In The Anatomy of Anxiety, holistic psychiatrist Dr. Ellen Vora offers nothing less than a paradigm shift in our understanding of anxiety and mental health, suggesting that anxiety is not simply a brain disorder but a whole-body condition.

As a Yale School of Medicine physician, the New York Times best-selling author of Every Patient Tells a Story, and an inspiration and adviser for the hit Fox TV drama, House, M.D., Lisa Sanders has seen it all. And yet, she is often confounded by the cases she describes in her column: unexpected collections of symptoms that she and other physicians struggle to diagnose. Dr. Sanders shows how making the right diagnosis requires expertise, painstaking procedure, and sometimes a little luck.

For over three decades, Ray Kurzweil has been one of the most respected and provocative advocates of the role of technology in our future. In his classic The Age of Spiritual Machines, he argued that computers would soon rival the full range of human intelligence at its best. Now he examines the next step in this inexorable evolutionary process: The union of human and machine, in which the knowledge and skills embedded in our brains will be combined with the vastly greater capacity, speed, and knowledge-sharing ability of our creations.

Dr. Carl Sagan takes us on a great adventure, offering his vivid and startling insight into the brain of man and beast, the origin of human intelligence, the function of our most haunting legends - and their amazing links to recent discoveries.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

Trauma is a fact of life. Veterans and their families deal with the painful aftermath of combat; one in five Americans has been molested; one in four grew up with alcoholics; one in three couples have engaged in physical violence. Dr. Bessel van der Kolk, one of the world’s foremost experts on trauma, has spent more than three decades working with survivors. In The Body Keeps the Score, he uses recent scientific advances to show how trauma literally reshapes both body and brain, compromising sufferers’ capacities for pleasure, engagement, self-control, and trust.

This original and lucid account of the complexities of love and its essential role in human well-being draws on the latest scientific research. Three eminent psychiatrists tackle the difficult task of reconciling what artists and thinkers have known for thousands of years about the human heart with what has only recently been learned about the primitive functions of the human brain.

The shark attacked while she was snorkeling, tearing through Micki Glenn’s breast and shredding her right arm. Her husband, a surgeon, saved her life on the spot, but when she was safely home she couldn’t just go on with her life. She had entered an even more profound survival journey: the aftermath. The survival experience changes everything because it invalidates all your previous adaptations, and the old rules don’t apply. In some cases survivors suffer more in the aftermath than they did during the actual crisis. In all cases, they have to work hard to reinvent themselves.

Is there a God? It's a question billions of people have asked since the dawn of time. You would think by now we'd have a satisfactory, universal answer. No such luck...or maybe we do and we just need to look in the right place. For Dr. Jay Lombard that place is the brain, and more importantly the mind, that center of awareness and consciousness that creates reality. In The Mind of God, Dr. Lombard employs case studies from his own behavioral neurology practice to explore the spiritual conundrums that we all ask ourselves.

Trauma is a fact of life. Veterans and their families deal with the painful aftermath of combat; one in five Americans has been molested; one in four grew up with alcoholics; one in three couples have engaged in physical violence. Dr. Bessel van der Kolk, one of the world’s foremost experts on trauma, has spent more than three decades working with survivors. In The Body Keeps the Score, he uses recent scientific advances to show how trauma literally reshapes both body and brain, compromising sufferers’ capacities for pleasure, engagement, self-control, and trust.

From the best-selling author of Gratitude and On the Move, a final volume of essays that showcase Sacks's broad range of interests - from his passion for ferns, swimming, and horsetails, to his final case histories exploring schizophrenia, dementia, and Alzheimer's.

Sleep. Memory. Pleasure. Fear. Language. We experience these things every day, but how do our brains create them? Your Brain, Explained is a personal tour around your gray matter. Neuroscientist Marc Dingman gives you a crash course in how your brain works and explains the latest research on the brain functions that affect you on a daily basis. You'll also discover what happens when the brain doesn't work the way it should, causing problems such as insomnia, ADHD, depression, or addiction.

Brilliantly exploring today's cutting edge brain research, Mind Wide Open allows readers to understand themselves and the people in their lives as never before. Using a mix of experiential reportage, personal storytelling, and fresh scientific discovery, Steven Johnson describes how the brain works and how its systems connect to the day-to-day realities of individual lives.

The psychiatric establishment and rehab industry in the Western world have branded addiction a brain disease based on evidence that brains change with drug use. But in The Biology of Desire, cognitive neuroscientist and former addict Marc Lewis makes a convincing case that addiction is not a disease and shows why the disease model has become an obstacle to healing. Lewis reveals addiction as an unintended consequence of the brain doing what it's supposed to do - seek pleasure and relief - in a world that's not cooperating.

Falling into the Fire is psychiatrist Christine Montross's thoughtful investigation of the gripping patient encounters that have challenged and deepened her practice. Beautifully written, deeply felt, Falling into the Fire brings us inside the doctor’s mind, illuminating the grave human costs of mental illness as well as the challenges of diagnosis and treatment. At once rigorous and meditative, Falling into the Fire is an intimate portrait of psychiatry, allowing the reader to witness the humanity of the practice and the enduring mysteries of the mind.

An astonishing new science called neuroplasticity is overthrowing the centuries-old notion that the human brain is immutable. Psychiatrist and psychoanalyst, Norman Doidge, MD, traveled the country to meet both the brilliant scientists championing neuroplasticity and the people whose lives they've transformed - people whose mental limitations or brain damage were seen as unalterable.

Mr. A. was admitted to Dr. Joel Gold’s inpatient unit at Bellevue Hospital in 2002. He was, he said, being filmed constantly, and his life was being broadcast around the world "like The Truman Show" - the 1998 film depicting a man who is unknowingly living out his life as the star of a popular soap opera. Over the next few years, Gold saw a number of patients suffering from what he and his brother, Dr. Ian Gold, began calling the "Truman Show Delusion," launching them on a quest to understand the nature of this particular phenomenon and the nature of madness itself.

John Ratey, best-selling author and clinical professor of psychiatry at Harvard Medical School, lucidly explains the human brain's workings, and paves the way for a better understanding of how the brain affects who we are. Ratey provides insight into the basic structure and chemistry of the brain, and demonstrates how its systems shape our perceptions, emotions, and behavior. By giving us a greater understanding of how the brain responds to the guidance of its user, he provides us with knowledge that can enable us to improve our lives.

The idea that “thoughts become things” has become a meme in popular culture. It’s held as a firm proposition in metaphysics, and some spiritual teachers ascribe infinite powers to the mind. But are these claims scientifically accurate? What does the scientific evidence tell us about the scope of the human mind to transform thoughts into reality?

One day Donna Jackson Nakazawa found herself lying on the floor to recover from climbing the stairs. That’s when it hit her. She was managing the symptoms of the autoimmune disorders that had plagued her for a decade, but she had lost her joy. As a science journalist, she was curious to know what mind-body strategies might help her. As a wife and mother she was determined to get her life back. Over the course of one year, Nakazawa researches and tests a variety of therapies including meditation, yoga, and acupuncture to find out what works.

Have you ever wondered why you have a brain? Let renowned neuroscientist Lisa Feldman Barrett demystify that big gray blob between your ears. In seven short essays (plus a bite-sized story about how brains evolved), this slim, entertaining, and accessible collection reveals mind-expanding lessons from the front lines of neuroscience research. You'll learn where brains came from, how they're structured (and why it matters), and how yours works in tandem with other brains to create everything you experience.

Does your dog get sad when you leave for the day? Does your cat purr because she loves you? Do bears attack when they’re angry? You can’t very well ask them. In fact, scientists haven’t been able to reach a consensus on whether animals even have emotions like humans do, let alone how to study them. Yet studies of animal emotion are critical for understanding human emotion and mental illness. In The Nature of the Beast, pioneering neuroscientist David J. Anderson describes a new approach to solving this problem.

Karl Deisseroth ha dedicado su vida a la comprensión de la mente y es uno de los pocos neurólogos que además son psiquiatras con consulta en activo. Esa combinación da lugar a un enfoque extremadamente original que busca la base biológica de las enfermedades mentales. A partir de una investigación puntera y de la experiencia con sus propios pacientes, narra, con una profunda empatía, la gran historia de los orígenes de las emociones humanas.

Imagine, if you will, a disease - one that has only subtle outward symptoms but can hijack your entire body without notice; one that transfers easily between parent and child; one that can last a lifetime if untreated. According to Dr. Paul Conti, this is exactly how society should conceptualize trauma: as an out-of-control epidemic with a potentially fatal prognosis. In Trauma: The Invisible Epidemic, Dr. Conti examines the most recent research, clinical best practices, and dozens of real-life stories to present a deeper, richer, and more urgent view of trauma.

The science of emotion is in the midst of a revolution on par with the discovery of relativity in physics and natural selection in biology. Leading the charge is psychologist and neuroscientist Lisa Feldman Barrett, whose research overturns the long-standing belief that emotions are automatic, universal, and hardwired in different brain regions. Instead, Barrett shows, we construct each instance of emotion through a unique interplay of brain, body, and culture.

The cells in our bodies consist of molecules, made up of the same carbon, oxygen, and hydrogen atoms found in air and rocks. But molecules, such as water and sugar, are not alive. So how do our cells - assemblies of otherwise "dead" molecules - come to life, and together constitute a living being? In Life’s Ratchet, physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale.

This book is about pleasure. It’s also about pain. Most important, it’s about how to find the delicate balance between the two, and why now more than ever finding balance is essential. We’re living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting....

There's a silent epidemic in Western civilization, and it is right under our noses. Our jaws are getting smaller and our teeth crooked and crowded, creating not only aesthetic challenges but also difficulties with breathing. Sandra Kahn and Paul R. Ehrlich, a pioneering orthodontist and a world-renowned evolutionist, respectively, present the biological, dietary, and cultural changes that have driven us toward this major health challenge. They propose simple adjustments that can alleviate this developing crisis.

Science is how we understand the world. Yet failures in peer review and mistakes in statistics have rendered a shocking number of scientific studies useless—or, worse, badly misleading. Such errors have distorted our knowledge in fields as wide-ranging as medicine, physics, nutrition, education, genetics, economics, and the search for extraterrestrial life. As Science Fictions makes clear, the current system of research funding and publication not only fails to safeguard us from blunders but actively encourages bad science—with sometimes deadly consequences.

Beginning with an in-depth explanation of the circadian clock - why it's important, how it works, and how to know it isn't working - The Circadian Code outlines lifestyle changes to make to get back on track. It's a concrete plan to enhance weight loss, improve sleep, optimize exercise, and manage technology so that it doesn't interfere with your body's natural rhythm. Dr. Panda's life changing methods show you how to prevent and reverse ailments like diabetes, cancer, and dementia, as well as microbiome conditions like acid reflux, heartburn, and irritable bowel disease.

In 1714, England's Parliament offered a huge reward to anyone whose method of measuring longitude could be proven successful. The scientific establishment--from Galileo to Sir Isaac Newton--had mapped the heavens in its certainty of a celestial answer. In stark contrast, one man, John Harrison, dared to imagine a mechanical solution--a clock that would keep precise time at sea, something no clock had been able to do on land. And the race was on....