Showing titles in Genetics

In 1994 Professor Bryan Sykes, a leading world authority on DNA and human evolution, was called in to examine the frozen remains of a man trapped in glacial ice in northern Italy. News of both the Ice Man's discovery and his age, which was put at over 5,000 years, fascinated scientists and newspapers throughout the world. But what made Sykes's story particularly revelatory was his successful identification of a genetic descendant of the Ice Man, a woman living in Great Britain today. How was Sykes able to locate a living relative?

Short, sassy, and bold, Mean Genes reveals that our struggles for self-improvement are, in fact, battles against our own genes - genes that helped our distant ancestors flourish, but are selfish and out of place in the modern world.

Ancestor Trouble is one writer’s attempt to use genealogy - a once-niche hobby that has grown into a multi-billion-dollar industry - to expose the secrets and contradictions of her own ancestors, and to argue for the transformational possibilities that reckoning with our ancestors offers all of us.

Just in the last three years a flood of new scientific findings, driven by revelations discovered in the human genome, has provided compelling new answers to many long-standing mysteries about our most ancient ancestors, the people who first evolved in Africa and then went on to colonize the whole world. Nicholas Wade weaves this host of news-making findings together for the first time into an intriguing new history of the human story before the dawn of civilization.

In 2018, scientists manipulated the DNA of human babies for the first time. As biologist and historian Matthew Cobb shows in As Gods, this achievement was one many scientists have feared from the start of the genetic age. Four times in the last fifty years, geneticists, frightened by their own technology, have called a temporary halt to their experiments. They ought to be frightened.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

Scientists' understanding of life is progressing more rapidly than at any point in human history, from the extraordinary decoding of DNA to the controversial emergence of biotechnology. Featuring pioneering biologists, geneticists, physicists, and science writers, Life explains just how far we've come - and takes a brilliantly educated guess at where we're heading.

The Gene is the story of one of the most powerful and dangerous ideas in our history, from best-selling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a 'unit of heredity'.

In The Lost Family, journalist Libby Copeland investigates what happens when we embark on a vast social experiment with little understanding of the ramifications. Copeland explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story.

Drawing on startling new evidence from the mapping of the genome, an explosive new account of the genetic basis of race and its role in the human story. Human evolution, the consensus view insists, ended in prehistory. Inconveniently, as Nicholas Wade argues in A Troublesome Inheritance, the consensus view cannot be right. And in fact, we know that populations have changed in the past few thousand years - to be lactose tolerant, for example, and to survive at high altitudes.

For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes.

Two-thirds of the American population are overweight or obese and suffering from chronic diseases directly related to our lifestyle choices. We live in a healthcare system that goes for quick fixes and medications instead of long-term solutions to solve problems. With all the information out there on fad diets and pills to quickly get to your goal of losing weight, we have realized that your health and wellness doesn’t come with an owner's manual. No matter how different our genes or life experiences may be, or how differently our plastic brains are wired by our experience, we have to ...

Well-meaning physicians, parents, and even scientists today often spread misinformation about what biology can and can't tell us about our bodies, minds, and identities. In this accessible, myth-busting book, geneticist Shoumita Dasgupta draws on the latest science to correct common misconceptions about how much of our social identities are actually based in genetics.

Engrossing and captivating, Editing Humanity takes listeners inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces listeners to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.

Biology is undergoing a quiet but profound transformation. Several aspects of the standard picture of how life works—the idea of the genome as a blueprint, of genes as instructions for building an organism, of proteins as precisely tailored molecular machines, of cells as entities with fixed identities, and more—have been exposed as incomplete, misleading, or wrong. In How Life Works, Philip Ball explores the new biology, revealing life to be a far richer, more ingenious affair than we had guessed.

In Valley of Forgetting, Jennie Erin Smith brings listeners into the clinic, the laboratories, and the Medellín trial center where Lopera’s patients receive an experimental drug to see if Alzheimer’s can be averted. She chronicles the lives of people who care for sick parents, spouses, and siblings, all while struggling to keep their own dreams afloat.

In recent years, genetic testing has become easily available to consumers across the globe, making it relatively simple to find out where your ancestors came from. But what do these test results actually tell us about ourselves? In Ancestors, Pierre Zalloua, a leading authority on population genetics, argues that these test results have led to a dangerous oversimplification of what one’s genetic heritage means. Genetic ancestry has become conflated with anthropological categories such as “origin,” “ethnicity,” and even “race” in spite of the complexities that underlie these concepts.

In Arrival of the Fittest, renowned evolutionary biologist Andreas Wagner draws on over 15 years of research to present the missing piece in Darwin's theory. Using experimental and computational technologies that were heretofore unimagined, he has found that adaptations are not just driven by chance, but by a set of laws that allow nature to discover new molecules and mechanisms in a fraction of the time that random variation would take.

Red is a brilliantly told, captivating history of red hair throughout the ages. An audiobook that breaks new ground, dispels myths, and reinforces the special nature of being a redhead, with a look at multiple disciplines, including science, religion, politics, feminism and sexuality, literature, and art. With an obsessive fascination that is as contagious as it is compelling, author Jacky Colliss Harvey (herself a redhead) begins her exploration of red hair in prehistory and traces the redhead gene as it made its way out of Africa with the early human diaspora.

You are just 10% human. For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony. Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.