Lithium
A Doctor, a Drug, and a Breakthrough
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Narrated by:
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Shawn Compton
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By:
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Walter A. Brown
About this listen
From insulin comas and lobotomy to incarceration and exile, Walter Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade's "Lithium Salts in the Treatment of Psychotic Excitement" described, for the first time, lithium's astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide. And yet, as Brown shows, it would be decades before lithium would overcome widespread stigmatization as a dangerous substance, and the resistance from the pharmaceutical industry, which had little incentive to promote a naturally occurring drug that could not be patented.
Brown also provides a vivid portrait of the story's unlikely hero, John Cade, a devoted naturalist who, unlike many modern medical researchers, did not benefit from prestigious research training or big funding sources. In this revelatory biography of a drug and the man who fought for its discovery, Brown crafts a captivating picture of modern medical history - revealing just how close we came to passing over this extraordinary cure.
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In Saving Normal, Allen Frances, one of the world's most influential psychiatrists, warns that mislabeling everyday problems as mental illness has shocking implications for individuals and society: Stigmatizing a healthy person as mentally ill leads to unnecessary, harmful medications, the narrowing of horizons, misallocation of medical resources, and draining of the budgets of families and the nation.
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Right on the money
- By Mentecuerpo on 03-29-19
By: Allen Frances MD
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The Problem of Alzheimer's
- How Science, Culture, and Politics Turned a Rare Disease into a Crisis and What We Can Do About It
- By: Jason Karlawish
- Narrated by: Jason Karlawish, Jonathan Todd Ross
- Length: 13 hrs and 41 mins
- Unabridged
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In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.
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A must read
- By kara kuntz on 05-20-21
By: Jason Karlawish
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Drugged: The Science and Culture Behind Psychotropic Drugs
- By: Richard J. Miller
- Narrated by: Roger Clark
- Length: 15 hrs and 42 mins
- Unabridged
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In Drugged, Miller takes listeners on an eye-opening tour of psychotropic drugs, describing the various kinds, how they were discovered and developed, and how they have played multiple roles in virtually every culture. Drugged brims with surprises, revealing the fact that antidepressant drugs evolved from rocket fuel, highlighting the role of hallucinogens in the history of religion, and asking whether Prozac can help depressed cats. Entertaining and authoritative, Drugged is a truly fascinating book.
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Interesting reading but heavy on the biochemistry
- By Scott on 06-28-14
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- By: Thomas Hager
- Narrated by: Angelo Di Loreto
- Length: 8 hrs and 39 mins
- Unabridged
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Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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Engrossing to physicians & lay persons alike
- By C. White on 03-08-19
By: Thomas Hager
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The Language of Life
- DNA and the Revolution in Personalized Medicine
- By: Francis S. Collins
- Narrated by: Greg Itzin
- Length: 10 hrs and 45 mins
- Unabridged
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A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine.
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The future of medicine
- By Ronald E on 04-12-10
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The HPV Vaccine on Trial
- Seeking Justice for a Generation Betrayed
- By: Mary Holland, Kim Mack Rosenberg, Eileen Iorio
- Narrated by: Caroline Slaughter
- Length: 13 hrs and 41 mins
- Unabridged
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Cancer strikes fear in people’s hearts around globe. So the appearance of a vaccine to prevent cancer - as we are assured the human papillomavirus (HPV) vaccine will - seemed like a game-changer. Since 2006, over 80 countries have approved the vaccine, with glowing endorsements from the world’s foremost medical authorities. Bringing in over $2.5 billion in annual sales, the HPV vaccine is a pharmaceutical juggernaut. Yet scandal now engulfs it worldwide. The HPV Vaccine on Trial is a shocking tale, chronicling the global efforts to sell and compel this alleged miracle.
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Outstanding Investigative Book!
- By Barbara Loeppke on 10-02-19
By: Mary Holland, and others
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Crazy Like Us
- The Globalization of the American Psyche
- By: Ethan Watters
- Narrated by: Patrick Lawlor
- Length: 8 hrs and 57 mins
- Unabridged
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America has been the world leader in generating new mental health treatments and modern theories of the human psyche. We export our psychopharmaceuticals packaged with the certainty that our biomedical knowledge will relieve the suffering and stigma of mental illness. We categorize disorders, thereby defining mental illness and health, and then parade these seemingly scientific certainties in front of the world.
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He is a reporter...
- By Briana on 05-07-18
By: Ethan Watters
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Between Hope and Fear
- A History of Vaccines and Human Immunity
- By: Michael Kinch
- Narrated by: Mel Foster
- Length: 15 hrs and 59 mins
- Unabridged
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Between Hope and Fear tells the remarkable story of vaccine-preventable infectious diseases and their social and political implications. While detailing the history of vaccine invention, Michael Kinch reveals the ominous reality that our victories against vaccine-preventable diseases are not permanent - and could easily be undone. Between Hope and Fear relates the remarkable intersection of science, technology, and disease that has helped eradicate many of the deadliest plagues known to man.
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Enjoyed
- By Minsi Zhang on 05-03-20
By: Michael Kinch
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The Book of Woe
- The DSM and the Unmaking of Psychiatry
- By: Gary Greenberg
- Narrated by: David Drummond
- Length: 14 hrs
- Unabridged
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For more than two years, author and psychotherapist Gary Greenberg has embedded himself in the war that broke out over the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (the DSM) - the American Psychiatric Association's (APA) compendium of mental illnesses and what Greenberg calls "the book of woe". Since its debut in 1952, the book has been frequently revised, and with each revision, the "official" view on which psychological problems constitute mental illness has changed.
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Disappointment
- By NYNM on 06-03-13
By: Gary Greenberg
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The Panic Virus
- A True Story of Medicine, Science, and Fear
- By: Seth Mnookin
- Narrated by: Dan John Miller
- Length: 10 hrs and 44 mins
- Unabridged
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The Panic Virus is a gripping scientific detective story about how grassroots radicals, snake-oil salesmen, and cynical journalists have perpetrated the biggest health-scare hoax of all time. It explores what happens when the media treats all viewpoints as equally valid, regardless of facts, from parents who are convinced that vaccines caused their children's autism to right-wing radicals who believe that climate change is a myth
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Incredible thorough journey
- By Rachel Dewald on 03-22-11
By: Seth Mnookin
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A Nation in Pain
- Healing Our Biggest Health Problem
- By: Judy Foreman
- Narrated by: Karen White
- Length: 14 hrs and 57 mins
- Unabridged
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Published in partnership with the International Association for the Study of Pain, A Nation in Pain offers a sweeping, deeply researched account of the chronic pain crisis, from neurobiology to public policy, and presents practical solutions that are within our grasp today. Drawing on both her personal experience with chronic pain and her background as an award-winning health journalist, she guides us through recent scientific discoveries, including genetic susceptibility to pain.
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Broad but superficial.
- By J. P. Murphy on 07-03-15
By: Judy Foreman
What listeners say about Lithium
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Gerald Albertson
- 02-08-23
A fine and well told story.
I suspect the major downside will be not enough readers with a keen interest in the Lithium story and the personalities that shaped it. The narration is superb. The book is not a thriller or a drama. Although some of each could have been written in. I’d like to see it on a bit larger stage than the niche market where I believe it will forever reside. The story deserves a second chance.
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- Safe Harbor
- 08-17-19
Good read great information
This a good historical perspective of lithium and how lithium came to be a valuable tool. I enjoyed this read and would recommend it to anyone interested in lithium and its uses and history.
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1 person found this helpful
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- Josie Swails
- 05-10-24
An Outstanding Tale About Medical History
I loved everything about this book - from the storyline, to the narrator, to the epilogue. If you're at all curious about the history of mood stabilizers, this book is for you.
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- Adria Jenny Amenti
- 07-20-20
Thorough historical overview
Thorough and interesting history that gets somewhat bogged down with the exhaustive details of one study and researcher after another. Still worth the listen.
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