By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight-how the same simple chemistry gives rise to life and causes our demise.

The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

Rosalind Franklin was what can only be called an overlooked genius. Although she was not fully credited for the feat at the time, her work led to major breakthroughs in our understanding of DNA. In fact, she took the first X-ray photo of DNA in all of its double helix glory. By the time her former colleagues were being showered with accolades for results they made at least partially based on her findings, Franklin would not be around to see it. Sadly, it’s believed that her use of X-ray equipment gave her terminal cancer, cutting her life short at age 37.

The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".

Rosalind Franklin has always been an outsider - brilliant, but different. Whether working at the laboratory she adored in Paris or toiling at a university in London, she feels closest to the science, those unchanging laws of physics and chemistry that guide her experiments. When she is assigned to work on DNA, she believes she can unearth its secrets. Rosalind knows if she just takes one more X-ray picture - one more after thousands - she can unlock the building blocks of life.

The audiobook is focused and high-yield, covering the most important topics you might expect to learn in a typical undergraduate organic chemistry course. The material is accurate, up-to-date, and broken down into bite-sized chapters. There are key takeaways following each chapter to drive home key points and quizzes to review commonly tested questions.

Cities and countries engulfed by panic and death, desperate for vaccines but fearful of what inoculation may bring. This is what the world has just gone through with Covid-19. But as Simon Schama shows in his epic history of vulnerable humanity caught between the terror of contagion and the ingenuity of science, it has happened before.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.

Paulo Coelho's enchanting novel has inspired a devoted following around the world. This story, dazzling in its simplicity and wisdom, is about an Andalusian shepherd boy named Santiago who travels from his homeland in Spain to the Egyptian desert in search of treasure buried in the Pyramids. Along the way he meets a Gypsy woman, a man who calls himself king, and an Alchemist, all of whom point Santiago in the direction of his quest.

With insight, humor, formal invention, and lyricism, in A Man of Two Faces Viet Thanh Nguyen rewinds the film of his own life. He expands the genre of personal memoir by acknowledging larger stories of refugeehood, colonization, and ideas about Vietnam and America, writing with his trademark sardonic wit and incisive analysis, as well as a deep emotional openness about his life as a father and a son.

J. Robert Oppenheimer was one of the iconic figures of the 20th century, a brilliant physicist who led the effort to build the atomic bomb but later confronted the moral consequences of scientific progress. When he proposed international controls over atomic materials, opposed the development of the hydrogen bomb, and criticized plans for a nuclear war, his ideas were anathema to powerful advocates of a massive nuclear buildup during the anti-Communist hysteria of the early 1950s.

Barely 50 years ago a computer was a gargantuan, vastly expensive thing that only a handful of scientists had ever seen. The world's brightest engineers were stymied in their quest to make these machines small and affordable until the solution finally came from two ingenious young Americans. Jack Kilby and Robert Noyce hit upon the stunning discovery that would make possible the silicon microchip, a work that would ultimately earn Kilby the Nobel Prize for physics in 2000.

In 1963, a female student was attending a lecture given by Nobel Prize winner James Watson, then tenured at Harvard. At nineteen, she was struggling to define her future. She had given herself just ten years to fulfill her professional ambitions before starting the family she was expected to have. For women at that time, a future on the usual path of academic science was unimaginable—but during that lecture, young Nancy Hopkins fell in love with the promise of genetics. Confidently believing science to be a pure meritocracy, she embarked on a career.

Paul Dirac was among the great scientific geniuses of the modern age. One of the discoverers of quantum mechanics, the most revolutionary theory of the past century, his contributions had a unique insight, eloquence, clarity, and mathematical power. His prediction of antimatter was one of the greatest triumphs in the history of physics.

Claude Shannon was a tinkerer, a playful wunderkind, a groundbreaking polymath, and a digital pioneer whose insights made the Information Age possible. He constructed fire-breathing trumpets and customized unicycles, outfoxed Vegas casinos, and built juggling robots, but he also wrote the seminal text of the Digital Revolution. That work allowed scientists to measure and manipulate information as objectively as any physical object. His work gave mathematicians and engineers the tools to bring that world to pass.

Derek Parfit (1942–2017) is the most famous philosopher most people have never heard of. Widely regarded as one of the greatest moral thinkers of the past hundred years, Parfit was anything but a public intellectual. Yet his ideas have shaped the way philosophers think about things that affect us all: equality, altruism, what we owe to future generations, and even what it means to be a person. In Parfit, David Edmonds presents the first biography of an intriguing, obsessive, and eccentric genius.

In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation.

Robert Oppenheimer was among the most brilliant and divisive of men. As head of the Los Alamos Laboratory, he oversaw the successful effort to beat the Nazis in the race to develop the first atomic bomb – a breakthrough that was to have eternal ramifications for mankind and that made Oppenheimer the “Father of the Atomic Bomb.” But with his actions leading up to that great achievement, he also set himself on a dangerous collision course with Senator Joseph McCarthy and his witch-hunters. In Robert Oppenheimer: A Life Inside the Center, Ray Monk, author of peerless biographies of Ludwig Wittgenstein and Bertrand Russell, goes deeper than any previous biographer in the quest to solve the enigma of Oppenheimer’s motivations and his complex personality.

What is genius? The word evokes iconic figures like Einstein, Beethoven, Picasso, and Steve Jobs, whose cultural contributions have irreversibly shaped society. Yet Beethoven could not multiply. Picasso couldn’t pass a fourth grade math test. And Jobs left high school with a 2.65 GPA. The Hidden Habits of Genius explores the meaning of this contested term, and the unexpected motivations of those we have dubbed "genius" throughout history, from Charles Darwin and Marie Curie to Leonardo Da Vinci and Andy Warhol to Toni Morrison and Elon Musk.

When he died in 1930 aged 26, Frank Ramsey had already invented one branch of mathematics and two branches of economics, laying the foundations for decision theory and game theory. Keynes deferred to him; he was the only philosopher whom Wittgenstein treated as an equal. Had he lived he might have been recognized as the most brilliant thinker of the century. This amiable shambling bear of a man was an ardent socialist, a believer in free love, and an intimate of the Bloomsbury set. For the first time Cheryl Misak tells the full story of his extraordinary life.

Planning the invasion of Normandy, the Allies knew that decoding the communications of the Nazi high command was imperative for its success. But standing in their way was an encryption machine they called Tunny (British English for “tuna”), which was vastly more difficult to crack than the infamous Enigma cipher.

The history of European philosophy is usually constructed from the work of men. In Metaphysical Animals, a pioneering group biography, Clare Mac Cumhaill and Rachael Wiseman offer a compelling alternative. In the mid-twentieth century Elizabeth Anscombe, Mary Midgley, Philippa Foot, and Iris Murdoch were philosophy students at Oxford when most male undergraduates and many tutors were conscripted away to fight in the Second World War. Together, these young women, all friends, developed a philosophy that could respond to the war’s darkest revelations.

Few recognize how the Great War, the industrialized slaughter that bled Europe from 1914 to 1918, shaped Einstein’s life and work. While Einstein never held a rifle, he formulated general relativity blockaded in Berlin, literally starving. He lost 50 pounds in three months, unable to communicate with his most important colleagues. Some of those colleagues fought against rabid nationalism; others were busy inventing chemical warfare - scientists trapped in the power plays of empire. Meanwhile, Einstein struggled to craft relativity and persuade the world that it was correct.

In the late 1930s, legendary financier, philanthropist, and society figure Alfred Lee Loomis gathered the most visionary scientific minds of the 20th century at his state-of-the-art laboratory in Tuxedo Park, New York. He established a top-secret defense laboratory at MIT and personally bankrolled pioneering research into new, high-powered radar detection systems that helped defeat the German Air Force and U-boats. With Ernest Lawrence, he pushed Franklin Delano Roosevelt to fund research in nuclear fission, which led to the development of the atomic bomb.

Nine remarkable men produced inventions that changed the world. The printing press, the telephone, powered flight, recording and others have made the modern world what it is. But who were the men who had these ideas and made reality of them? As David Angus shows, they were very different - quiet, boisterous, confident, withdrawn - but all had a moment of vision allied to single-minded determination to battle through numerous prototypes and produced something that really worked. This is a fascinating account for younger listeners.

Number-one New York Times best-selling author Dava Sobel returns with the captivating, little-known true story of a group of women whose remarkable contributions to the burgeoning field of astronomy forever changed our understanding of the stars and our place in the universe.

Lee Hood did that rarest of things. He enabled scientists to see things they couldn't see before and do things they hadn't dreamed of doing. Scientists can now sequence complete human genomes in a day, setting in motion a revolution that is personalizing medicine. Hood, a son of the American West, was an unlikely candidate to transform biology. But with ferocious drive, he led a team at Caltech that developed the automated DNA sequencer, the tool that paved the way for the Human Genome Project.

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the 20-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics.

Today it is common knowledge that the dinosaurs were wiped out by a meteorite impact 65 million years ago that killed half of all species then living. It is far less widely understood that a much greater catastrophe took place at the end of the Permian period 251 million years ago: at least 90 percent of life on earth was destroyed. When Life Nearly Died documents not only what happened during this gigantic mass extinction, but also the recent renewal of the idea of catastrophism.

James D. Watson, the Nobel laureate whose pioneering work helped unlock the mystery of DNA's structure, charts the greatest scientific journey of our time, from the discovery of the double helix to today's controversies to what the future may hold. Updated to include new findings in gene editing, epigenetics, and agricultural chemistry as well as two entirely new chapters on personal genomics and cancer research. This is the most comprehensive and authoritative exploration of DNA's impact on our society and our world.

In Quantum Physics: What Everyone Needs to Know, quantum physicist Michael G. Raymer distills the basic principles of such an abstract field, and addresses the many ways quantum physics is a key factor in today's science and beyond. The book tackles questions as broad as the meaning of quantum entanglement and as specific and timely as why governments worldwide are spending billions of dollars developing quantum technology research. Raymer's list of topics is diverse, and showcases the sheer range of questions and ideas in which quantum physics is involved.

Nearly a hundred years after its publication, Kurt Gödel's famous proof that every mathematical system must contain propositions that are true - yet never provable - continues to unsettle mathematics, philosophy, and computer science. Yet unlike Einstein, with whom he formed a warm and abiding friendship, Gödel has long escaped all but the most casual scrutiny of his life.

Throughout history, scientists have come up with theories and ideas that just don't seem to make sense. These we call paradoxes. The paradoxes Al-Khalili offers are drawn chiefly from physics and astronomy and represent those that have stumped some of the finest minds. With elegant explanations that bring the listener inside the mind of those who've developed them, Al-Khalili helps us to see that, in fact, paradoxes can be solved if seen from the right angle.

Gene Kranz was present at the creation of America's manned space program and was a key player in it for three decades. As a flight director in NASA's Mission Control, Kranz witnessed firsthand the making of history. He participated in the space program from the early days of the Mercury program to the last Apollo mission, and beyond. He endured the disastrous first years when rockets blew up and the United States seemed to fall further behind the Soviet Union in the space race.

For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As cardiologist and best-selling author Sandeep Jauhar tells in The Heart, it was only recently that we demolished age-old taboos and devised the transformative procedures that changed the way we live. Deftly alternating between historical episodes and his own work, Jauhar tells the colorful and little known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ.