
Never Enough
The Neuroscience and Experience of Addiction
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Narrated by:
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Judith Grisel
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By:
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Judith Grisel
About this listen
A New York Times Best Seller
From a renowned behavioral neuroscientist and recovering addict, a rare pause-resisting work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction.
Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after 25 years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey.
In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice.
With more than one in five people over the age of 14 addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a “cure” for addiction will not be found in our individual brains but in the way we interact with our communities.
Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial new insight into how we can solve the epidemic of abuse.
©2019 Judith Grisel (P)2019 Random House AudioListeners also enjoyed...
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Critic reviews
“Dr. Judith Grisel, a neuroscientist and a person in long term addiction recovery, juxtaposes stark examples from her own tortured past, methodically connecting each experience to the hard science of addiction neurobiology. Doing this captures our attention as we peer into one of the most complex puzzles of humankind. The science behind addiction comes alive in its sorrow and grandeur. When you pick up this book get ready for an intense ride.” (Paul H. Earley, MD, DFASAM; president-elect, American Society of Addiction Medicine)
“Grisel is a recovering addict, a neuroscientist, and a talented writer. Who better to help us understand drug addiction? This book is as informative as it is moving. Here you will find clearly explained science and a gripping account of the personal and societal toll of drug addiction.” (Martha J. Farah, PhD, director, Center for Neuroscience & Society, and Walter H. Annenberg professor in the natural sciences, University of Pennsylvania)
“It is rare to have a book on addiction marry emotional and scientific views. Never Enough sends a message of hope in relaying Judith Grisel’s pathway out of her own drug quagmire - notably, one triggered by the positive and compassionate responses of those near and dear to her.” (Christopher J. Evans, PhD, director, Hatos Center for Neuropharmacology, UCLA)
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We need a fundamental shift in our values—a pivot in how we think, act, work, and connect. Despite what we’ve been told, the most critical mainspring of social change isn’t coalition building or problem analysis. It’s healing: deep, whole, and systemic, inside and out. Here, Shawn Ginwright, PhD, breaks down the common myths of social movements—a set of deeply ingrained beliefs that actually hold us back from healing and achieving sustainable systemic change.
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Loved! Perfect for the newly minted PhD student interested in social justice
- By Tracee M. Tomlinson on 09-23-24
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The First Ten Years
- Two Sides of the Same Love Story
- By: Joseph Fink, Meg Bashwiner
- Narrated by: Joseph Fink, Meg Bashwiner
- Length: 6 hrs and 19 mins
- Unabridged
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In 2009, 22-year-old Joseph Fink, newly arrived to New York City from the West Coast, was juggling odd jobs to pay the rent and volunteering with a theater company in the East Village so he could snag free tickets to their shows. Meg Bashwiner, a 22-year-old aspiring performer and playwright, was living with her parents in New Jersey, working a desk job and commuting to her internship with that same East Village theater company.
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A fun glimpse into a good marriage
- By Steph on 06-12-21
By: Joseph Fink, and others
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Mindreader
- The New Science of Deciphering What People Really Think, What They Really Want, and Who They Really Are
- By: David J. Lieberman
- Narrated by: Sean Pratt
- Length: 6 hrs and 33 mins
- Unabridged
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What did your boss mean in that email? Is your mechanic stretching the truth? Whether you’re engaged in a casual conversation or a high-stakes negotiation, it’s critical to understand the subtext of a situation. But with so much interaction happening on screens—via email, texts, or video chat—we are losing the ability to interpret expressions and cues. Furthermore, since many are now savvy about the meaning of body language, it’s become even harder to discern someone’s true thoughts or intentions.
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Waste of a credit for common sense observations
- By Brendan on 08-30-22
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Failure to Launch
- Why Your Twentysomething Hasn't Grown Up...and What to Do About It
- By: Mark McConville Ph.D.
- Narrated by: Stephen Graybill
- Length: 7 hrs and 44 mins
- Unabridged
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In Dr. Mark McConville's decades of experience as a family clinical psychologist, perhaps no problem has been more fraught than that of young adults who fail to successfully transition from adolescence into adulthood. These kids - technically adults - just can't get it together: They can't hold a job, they struggle to develop meaningful relationships, and they often end up back in their parents' spare bedroom or on the couch. In fact, studies show that one in four Americans aged 25 to 34 neither work nor attend school - a problem that spans all socioeconomic and geographic boundaries.
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Thank you.
- By TWW on 07-22-21
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Brain Inflamed
- Uncovering the Hidden Causes of Anxiety, Depression, and Other Mood Disorders in Adolescents and Teens
- By: Kenneth Bock MD
- Narrated by: Stephen Graybill
- Length: 8 hrs and 51 mins
- Unabridged
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From renowned integrative family physician Dr. Kenneth Bock, a groundbreaking approach to understanding and treating mental health among adolescents and teens.
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Taking on the difficult cases
- By Mother of Chickens on 06-01-22
By: Kenneth Bock MD
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What Do You Say?
- How to Talk with Kids to Build Motivation, Stress Tolerance, and a Happy Home
- By: William Stixrud PhD, Ned Johnson
- Narrated by: Ned Johnson
- Length: 8 hrs and 39 mins
- Unabridged
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William Stixrud, PhD, and Ned Johnson have 60 years combined experience talking to kids one-on-one, and the most common question they get when out speaking to parents and educators is: What do you say? While many adults understand the importance and power of the philosophies behind the books that dominate the parenting bestseller list, parents are often left wondering how to put those concepts into action. Johnson and Stixrud show how to engage in respectful and effective dialogue, beginning with defining and demonstrating the basic principles of listening and speaking.
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Actionable Advice
- By elizabeth m holladay on 05-19-24
By: William Stixrud PhD, and others
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Together
- The Healing Power of Human Connection in a Sometimes Lonely World
- By: Vivek H. Murthy
- Narrated by: Vivek H. Murthy
- Length: 10 hrs and 53 mins
- Unabridged
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Humans are social creatures: In this simple and obvious fact lies both the problem and the solution to the current crisis of loneliness. In his groundbreaking audiobook, the 19th surgeon general of the United States Dr. Vivek Murthy makes a case for loneliness as a public health concern: a root cause and contributor to many of the epidemics sweeping the world today from alcohol and drug addiction to violence to depression and anxiety.
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Losing 7 Friends to Suicide, I’m Glad I Read This
- By Amit Bhuta on 05-04-20
By: Vivek H. Murthy
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The Resonance Effect
- How Frequency Specific Microcurrent Is Changing Medicine
- By: Carolyn McMakin, James L. Oschman - foreword
- Narrated by: Diana Gardiner
- Length: 9 hrs and 1 min
- Unabridged
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The Resonance Effect is both the author's story of her inspirational journey of having the courage to find her true calling and an account of the development of a remarkable newly rediscovered treatment, frequency-specific microcurrent (FSM), that takes advantage of the body's ability to respond to frequencies in order to heal a number of chronic conditions.
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Frequencies for the Future!
- By Audrey Moorehead on 10-21-20
By: Carolyn McMakin, and others
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Thrivers
- The Surprising Reasons Why Some Kids Struggle and Others Shine
- By: Michele Borba Ed D.
- Narrated by: Michele Borba Ed D.
- Length: 8 hrs and 58 mins
- Unabridged
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Michele Borba has been a teacher, educational consultant, and parent for 40 years - and she's never been more worried than she is about this current generation of kids. The high-achieving students she talks with every day are more accomplished, better educated, and more privileged than ever before. They're also more stressed, unhappier, and struggling with anxiety, depression, and burnout at younger and younger ages - "we're like pretty packages with nothing inside," said one young teen.
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Buy the book, NOT the AUDIOBOOK
- By AllieSmith on 02-23-24
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Undo It!
- How Simple Lifestyle Changes Can Reverse Most Chronic Diseases
- By: Dean Ornish M.D., Anne Ornish
- Narrated by: Dean Ornish M.D., Anne Ornish
- Length: 8 hrs and 34 mins
- Unabridged
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Fight cancer, diabetes, heart disease, weight gain, and even the aging process itself with one simple, scientifically proven plan to reverse disease - as well as prevent and reduce symptoms - from the world-renowned pioneer of lifestyle medicine.
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Surprisingly awful
- By Nicole K. on 03-22-19
By: Dean Ornish M.D., and others
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Brave, Not Perfect
- Fear Less, Fail More, and Live Bolder
- By: Reshma Saujani
- Narrated by: Reshma Saujani
- Length: 5 hrs and 26 mins
- Unabridged
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In this audiobook inspired by her popular TED Talk, the founder and CEO of Girls Who Code urges women to embrace imperfection and live a bolder, more authentic life. By choosing bravery over perfection, we can find the power to claim our voice, to leave behind what makes us unhappy, and to go for the things we genuinely, passionately want. In Brave, Not Perfect, Saujani shares powerful insights and practices to help us let go of our need for perfection and make bravery a lifelong habit.
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Good for Husbands Trying Understand their Wives Better
- By Corey Watts on 10-08-19
By: Reshma Saujani
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Win the Day
- 7 Daily Habits to Help You Stress Less & Accomplish More
- By: Mark Batterson
- Narrated by: Mark Batterson
- Length: 7 hrs and 46 mins
- Unabridged
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Too many people delay, downsize, or shrug off their dreams just because they don’t know where to start, but playing it safe doesn’t account for the massive cost of a life not fully lived. Win the Day is the jump-start you need to go after your goals, one day at a time.
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Mindset 🤔 is everything in 2021 🎯
- By Egbert Oostburg on 01-01-21
By: Mark Batterson
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It's About Damn Time
- How to Turn Being Underestimated into Your Greatest Advantage
- By: Arlan Hamilton, Rachel L. Nelson
- Narrated by: Arlan Hamilton
- Length: 5 hrs and 57 mins
- Unabridged
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In 2015, Arlan Hamilton was on food stamps and sleeping on the floor of the San Francisco airport, with nothing but an old laptop and a dream of breaking into the venture capital business. She couldn’t understand why people starting companies all looked the same (white and male), and she wanted the chance to invest in the ideas and people who didn’t conform to this image of how a founder is supposed to look. Hamilton had no contacts or network in Silicon Valley, no background in finance - not even a college degree. What she did have was fierce determination and the will to succeed.
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Very inspiring story
- By Abir Chermiti - EllePodTalks on 10-26-20
By: Arlan Hamilton, and others
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Life, I Swear
- Intimate Stories from Black Women on Identity, Healing, and Self-Trust
- By: Chloe Dulce Louvouezo
- Narrated by: Joniece Abbott-Pratt
- Length: 5 hrs and 13 mins
- Unabridged
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In this stunningly illustrated essay collection inspired by the popular podcast Life, I Swear, prominent Black women reflect on self-love and healing, sharing stories of the trials and tribulations they’ve faced and what has helped them confront pain, heal wounds, and find connection.
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This felt like home
- By nm on 11-16-21
What listeners say about Never Enough
Highly rated for:
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- Michael
- 04-26-19
An important read, just not on Audible
Grisel shares her own very personal story and an incredible wealth of neuroscience in a way that is accessible and meaningful. She is unflinchingly honest about the nature of addiction. She offers no magical cure but deep insight into how to humanely address addiction. Everyone should read this book.
My only critique is that her voice is soft and slow, making the content feel uninteresting at times. Also, the text is very heavy and complicated. I would highly reccomend the Kindle or paper version so one can really examine the text.
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9 people found this helpful
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- Brian LaRocca
- 10-07-19
A Great Work on Addiction
Drug addiction has gotten a lot more attention these days as the image of victims has morphed from inner city homeless people to grandmothers who have had trouble weaning themselves off of post-operative medication. This book is enlightening for those who have not known an addict. Judith Grisel is the perfect author to write this book: a neuroscientist with a decade of personal addiction.
She frames the problem in stark terms: a) 16% of Americans over the age of twelve have an addiction problem b) a quarter of deaths are attributable to drugs c) drug treatment consumes a tenth of all healthcare spending (or twice as much as what we spend on cancer) d) there has been little improvement in treatment e) and only 10% of intervention is successful.
The main culprits that lead to the disease are having a genetic predisposition, exposure (and even worse from puberty to adulthood), and a catalyzing environment. The genetic component is interesting as she uses the example that Asians who get flush are less likely to be alcoholics and smokers who tend to absorb more nicotine smoke less.
Grisel explores different classes of drugs and what you find is the common thread that there is no gain without a later, equal loss. As far back as Socrates, this interplay of pleasure and pain has been well known. For each high, you pay it back with low or as the Grateful Dead put it, "Too much is never enough."
She imparts such interesting facts such as:
- Valium in the 1970's was used by one in five women and sent more people to the hospital than all other illicit drugs
- The doctors who discovered barbiturates died of overdoses themselves
- In 2010, the of alcohol (in poor health, drunk driving, crime) was 249 billion
- Kat production uses up 40% of Yemen's water supply
- Since ecstasy, unlike cocaine, effects transporters and not receptors, addicts are never the same regardless of how long they have been clean
Paraphrasing Grisel in her summation of the range of drugs: Alcohol and downers are negatively reinforcing because they reduce anxiety, Opiates reduce suffering, Stimulants reduce boredom. People tend to abuse those drugs that compliment themselves (such as the anxious who prefer alcohol) but also someone who is nervous who drinks to self medicate will become nervous.
I wish there was an optimistic conclusion but by the end of reading this I was worried that my own daily coffee habit had impaired my natural ability to awaken. Dependence is hard to overcome. Grisel recounts the story of her sharing a crack pipe with a toothless, homeless person who was deluded into thinking he was on top of the world. Ultimately, it was not jail or seeing her friends dying but rather her reconnection with her father that led to her recovery. She herself advises decreasing the drug's dosage, supplying palliative medicine for the inevitable withdrawal, and creating a support network. She points out that addicts naturally posses what are typically beneficial traits, like being heterodox, strong-willed and persistent. These traits certainly are apparent in this excellent scientist's work.
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13 people found this helpful
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- Randall Allen
- 03-20-19
Up-to-date and informative
The story is amazing but true. Some of the terminology I struggled with but the basic idea she gets across through many examples. It is amazing this girl is alive but it's incredible that she survived and secured a PhD
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3 people found this helpful
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- Mads
- 08-30-20
Good and informative
I really enjoyed hearing the author’s story. The book was also very informative, I’m glad I listened because there was so much interesting stuff. A lot of the neuro info went over my head though but the readers voice was very relaxing so I didn’t mind the moments of confusion.
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- Amazon Customer
- 03-26-19
Loved it!
I am a physician - found the story engaging, the science fascinating and well explained. I have always tried to have compassion for people with addiction. Reading this book has
Given me additional insight, and has helped me become even more compassionate. The personal revelations are bravely bared. Very impressive.
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6 people found this helpful
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- fernando antonio hadba
- 09-05-19
Great balance!
This book is both a courageous self knowledge experience and a fantastic guide about drugs, their effects and our brain reaction.
Strongly recommend it
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1 person found this helpful
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- Anonymous User
- 03-11-25
Certainty
Her exquisite way of telling her story and how it was like she was telling mine. The comfort it brought and gentle way of reminding me of the pain I experienced leaving me feel less alone and also motivated to do more and be better.
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- Candice Merrick
- 03-21-19
homerun
fully loaded with information about most of the questions I have been wondering about. I am reading it for the second time.
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2 people found this helpful
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- R. MCRACKAN
- 09-13-19
Great research into an uncomfortable topic
Never Enough outlines the mechanics and dangers of the most common drugs. Despite the fact that this book very much should have used a narrator other than the author, it's a worthwhile listen which I highly recommend. I especially appreciated her analysis of pot, showing that while it's not the devil plant of early propaganda, it's also far from being benign or harmless.
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1 person found this helpful
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- Valerie Dudley
- 11-25-19
Very worthwhile and comprehensive book, from chocolate to heroin
This book is informative and interesting especially to a fellow addict. It does a good job of examining practical questions and giving in-depth answers that acknowledge a lack of certainty, I appreciated the complexity and lack of pigeon holing in the author’s conclusions. Her personal experience added a lot to the book, I could relate to her way of seeing addiction and why we do what we do.
Objectively researched and presented but put in a personal perspective that was effective. I liked it and want to listen to it again to ponder it some more. The ending conclusions clarified and elaborated on how I tend to view addiction.
A professional narrator may have been a better choice for audio version or some coaching on making it less low energy voice.
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1 person found this helpful