Never Enough
The Neuroscience and Experience of Addiction
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Narrated by:
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Judith Grisel
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By:
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Judith Grisel
About this listen
A New York Times Best Seller
From a renowned behavioral neuroscientist and recovering addict, a rare pause-resisting work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction.
Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after 25 years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey.
In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice.
With more than one in five people over the age of 14 addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a “cure” for addiction will not be found in our individual brains but in the way we interact with our communities.
Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial new insight into how we can solve the epidemic of abuse.
©2019 Judith Grisel (P)2019 Random House AudioListeners also enjoyed...
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Critic reviews
“Dr. Judith Grisel, a neuroscientist and a person in long term addiction recovery, juxtaposes stark examples from her own tortured past, methodically connecting each experience to the hard science of addiction neurobiology. Doing this captures our attention as we peer into one of the most complex puzzles of humankind. The science behind addiction comes alive in its sorrow and grandeur. When you pick up this book get ready for an intense ride.” (Paul H. Earley, MD, DFASAM; president-elect, American Society of Addiction Medicine)
“Grisel is a recovering addict, a neuroscientist, and a talented writer. Who better to help us understand drug addiction? This book is as informative as it is moving. Here you will find clearly explained science and a gripping account of the personal and societal toll of drug addiction.” (Martha J. Farah, PhD, director, Center for Neuroscience & Society, and Walter H. Annenberg professor in the natural sciences, University of Pennsylvania)
“It is rare to have a book on addiction marry emotional and scientific views. Never Enough sends a message of hope in relaying Judith Grisel’s pathway out of her own drug quagmire - notably, one triggered by the positive and compassionate responses of those near and dear to her.” (Christopher J. Evans, PhD, director, Hatos Center for Neuropharmacology, UCLA)
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- Length: 7 hrs and 32 mins
- Unabridged
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Sleep. Memory. Pleasure. Fear. Language. We experience these things every day, but how do our brains create them? Your Brain, Explained is a personal tour around your gray matter. Neuroscientist Marc Dingman gives you a crash course in how your brain works and explains the latest research on the brain functions that affect you on a daily basis. You'll also discover what happens when the brain doesn't work the way it should, causing problems such as insomnia, ADHD, depression, or addiction.
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Loved it!!
- By Amazon Customer on 05-04-22
By: Marc Dingman
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Why We Sleep
- Unlocking the Power of Sleep and Dreams
- By: Matthew Walker
- Narrated by: Steve West
- Length: 13 hrs and 52 mins
- Unabridged
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Sleep is one of the most important but least understood aspects of our life, wellness, and longevity. Until very recently, science had no answer to the question of why we sleep, or what good it served, or why we suffer such devastating health consequences when we don't sleep. Compared to the other basic drives in life - eating, drinking, and reproducing - the purpose of sleep remained elusive.
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I recommend this to EVERYONE
- By M. Balfour on 12-11-17
By: Matthew Walker
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Recover to Live
- Kick Any Habit, Manage Any Addiction: Your Self-Treatment Guide to Alcohol, Drugs, Eating Disorders, Gambling, Hoarding, Smoking, Sex, and Porn
- By: Christopher Kennedy Lawford
- Narrated by: Seth Michael Donsky
- Length: 13 hrs and 42 mins
- Unabridged
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From New York Times bestselling author of Symptoms of Withdrawal and Moments of Clarity Christopher Kennedy Lawford comes a book that will save lives. For most of his early life, Christopher Kennedy Lawford battled life-threatening drug and alcohol addictions. Now in recovery for more than 25 years, he works to effect change and raise global awareness of addiction in nonprofit, private, and government circles, serving as the goodwill ambassador for drug dependence treatment and care for the United Nations.
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I didn't know I was a workaholic
- By wh on 06-17-13
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The Biology of Desire
- Why Addiction Is Not a Disease
- By: Marc Lewis PhD
- Narrated by: Don Hagen
- Length: 7 hrs and 40 mins
- Unabridged
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Performance
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The psychiatric establishment and rehab industry in the Western world have branded addiction a brain disease based on evidence that brains change with drug use. But in The Biology of Desire, cognitive neuroscientist and former addict Marc Lewis makes a convincing case that addiction is not a disease and shows why the disease model has become an obstacle to healing. Lewis reveals addiction as an unintended consequence of the brain doing what it's supposed to do - seek pleasure and relief - in a world that's not cooperating.
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An important addition to understanding addiction.
- By Jeff M on 02-28-16
By: Marc Lewis PhD
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Trauma Recovery Through Psychedelic Experiences
- A Guide to Understanding and Safely Using MDMA, Psilocybin Mushrooms, Ayahuasca, Cannabis, LSD, DMT and More! For Addiction, Depression, PTSD & OCD
- By: Roy Clark
- Narrated by: Dan Levy
- Length: 5 hrs and 52 mins
- Unabridged
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Ready to move forward with your life and make meaningful changes, but you are regularly held back by mental health and/or trauma from your past? Unresolved trauma can cause a number of mental health conditions, but this doesn’t have to be the way life defines you forever. You deserve better!
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Okay overview, but there are much better resources
- By Matt Haag on 07-19-23
By: Roy Clark
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A Nation in Pain
- Healing Our Biggest Health Problem
- By: Judy Foreman
- Narrated by: Karen White
- Length: 14 hrs and 57 mins
- Unabridged
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Published in partnership with the International Association for the Study of Pain, A Nation in Pain offers a sweeping, deeply researched account of the chronic pain crisis, from neurobiology to public policy, and presents practical solutions that are within our grasp today. Drawing on both her personal experience with chronic pain and her background as an award-winning health journalist, she guides us through recent scientific discoveries, including genetic susceptibility to pain.
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Broad but superficial.
- By J. P. Murphy on 07-03-15
By: Judy Foreman
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The Expectation Effect
- How Your Mindset Can Change Your World
- By: David Robson
- Narrated by: John Sackville
- Length: 8 hrs and 45 mins
- Unabridged
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Melding neuroscience with narrative, science journalist David Robson takes lstenersi on a deep dive into the many life zones the expectation effect permeates. We see how people who believe stress is beneficial become more creative when placed under strain. We see how associating aging with wisdom can add seven plus years to your life. People say seeing is believing but, over and over, Robson proves that the converse is truer: Believing is seeing.
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Every leader and teacher must read!
- By Myron Golden on 09-18-22
By: David Robson
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The Psychopath Inside
- A Neuroscientist's Personal Journey into the Dark Side of the Brain
- By: James Fallon
- Narrated by: Walter Dixon
- Length: 4 hrs and 58 mins
- Unabridged
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The memoir of a neuroscientist whose research led him to a bizarre personal discovery, James Fallon had spent an entire career studying how our brains affect our behavior when his research suddenly turned personal. While studying brain scans of several family members, he discovered that one perfectly matched a pattern he’d found in the brains of serial killers. This meant one of two things: Either his family’s scans had been mixed up with those of felons or someone in his family was a psychopath.
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Entertaining story with some quick neuroscience
- By smarmer on 09-21-14
By: James Fallon
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The Depths
- The Evolutionary Origins of the Depression Epidemic
- By: Jonathan Rottenberg
- Narrated by: Walter Dixon
- Length: 4 hrs and 27 mins
- Unabridged
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Nearly every depressed person is assured by doctors, well-meaning friends and family, the media, and ubiquitous advertisements that the underlying problem is a chemical imbalance. Such a simple defect should be fixable, yet despite all of the resources that have been devoted to finding a pharmacological solution, depression remains stubbornly widespread. Why are we losing this fight?
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Great read for understanding
- By Adam on 02-04-15
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Brain Rules for Aging Well
- 10 Principles for Staying Vital, Happy, and Sharp
- By: John Medina
- Narrated by: John Medina
- Length: 8 hrs and 38 mins
- Unabridged
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How come I can never find my keys? Why don't I sleep as well as I used to? Why do my friends keep repeating the same stories? What can I do to keep my brain sharp? Scientists know. Brain Rules for Aging Well, by developmental molecular biologist Dr. John Medina, gives you the facts - and the prescription to age well - in his signature engaging style. With so many discoveries over the years, science is literally changing our minds about the optimal care and feeding of the brain. All of it is captivating. A great deal of it is unexpected.
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Scientific and practical
- By symya08 on 04-29-18
By: John Medina
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The Depression Cure
- The 6-Step Program to Beat Depression without Drugs
- By: Stephen S. Ilardi
- Narrated by: Jeffrey Kafer
- Length: 6 hrs and 49 mins
- Unabridged
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In the past decade, depression rates have skyrocketed, and one in four Americans will suffer from major depression at some point in their lives. Where have we gone wrong? Dr. Stephen S. Ilardi sheds light on our current predicament and reminds us that our bodies were never designed for the sleep-deprived, poorly nourished, frenzied pace of 21st-century life.
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I have a dear family member....
- By Derek B. on 12-12-12
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Transcendence
- Healing and Transformation Through Transcendental Meditation
- By: Norman E. Rosenthal
- Narrated by: Gildart Jackson
- Length: 8 hrs and 4 mins
- Unabridged
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Norman E. Rosenthal, M.D., a 20-year researcher at the National Institute of Mental Health and the celebrated psychiatrist who pioneered the study and treatment of Season Affective Disorder (SAD), brings us the most important work on Transcendental Meditation since the Maharishi Mahesh Yogi's Science of Being and Art of Living - and one of our generation's most significant books on achieving greater physical and mental health and wellness.
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Inspirational yet "Informercional"
- By James on 05-24-13
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Saving Normal
- An Insider’s Revolt Against out-of-Control Psychiatric Diagnosis, DSM-5, Big Pharma, and the Medicalization of Ordinary Life
- By: Allen Frances MD
- Narrated by: Paul Boehmer
- Length: 11 hrs and 53 mins
- Unabridged
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In Saving Normal, Allen Frances, one of the world's most influential psychiatrists, warns that mislabeling everyday problems as mental illness has shocking implications for individuals and society: Stigmatizing a healthy person as mentally ill leads to unnecessary, harmful medications, the narrowing of horizons, misallocation of medical resources, and draining of the budgets of families and the nation.
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Right on the money
- By Mentecuerpo on 03-29-19
By: Allen Frances MD
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A User's Guide to the Brain
- Perception, Attention, and the Four Theaters of the Brain
- By: John J. Ratey
- Narrated by: Eric Martin
- Length: 16 hrs and 38 mins
- Unabridged
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John Ratey, best-selling author and clinical professor of psychiatry at Harvard Medical School, lucidly explains the human brain's workings, and paves the way for a better understanding of how the brain affects who we are. Ratey provides insight into the basic structure and chemistry of the brain, and demonstrates how its systems shape our perceptions, emotions, and behavior. By giving us a greater understanding of how the brain responds to the guidance of its user, he provides us with knowledge that can enable us to improve our lives.
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Great book, mediocre narration
- By Dr. B on 09-25-18
By: John J. Ratey
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Gabor should have been the narrator
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If you saw this on Instagram ads you’re as gullible as I was
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With heart-racing urgency and unflinching honesty, Jenkins takes you inside the grips of addiction and the desperate decisions it breeds. She is a born storyteller who lived an incredible story, from blackmail by an ex-boyfriend to a soul-shattering deal with a drug dealer, and her telling brims with suspense and unexpected wit. But the true surprise is her path to recovery. Tiffany breaks through the stigma and silence to offer hope and inspiration to anyone battling the disease - whether it’s a loved one or themselves.
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I Get it, You Were an Addict
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What listeners say about Never Enough
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Amazon Customer
- 03-26-19
Loved it!
I am a physician - found the story engaging, the science fascinating and well explained. I have always tried to have compassion for people with addiction. Reading this book has
Given me additional insight, and has helped me become even more compassionate. The personal revelations are bravely bared. Very impressive.
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4 people found this helpful
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- fernando antonio hadba
- 09-05-19
Great balance!
This book is both a courageous self knowledge experience and a fantastic guide about drugs, their effects and our brain reaction.
Strongly recommend it
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1 person found this helpful
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- Michael
- 04-26-19
An important read, just not on Audible
Grisel shares her own very personal story and an incredible wealth of neuroscience in a way that is accessible and meaningful. She is unflinchingly honest about the nature of addiction. She offers no magical cure but deep insight into how to humanely address addiction. Everyone should read this book.
My only critique is that her voice is soft and slow, making the content feel uninteresting at times. Also, the text is very heavy and complicated. I would highly reccomend the Kindle or paper version so one can really examine the text.
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8 people found this helpful
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- Brian LaRocca
- 10-07-19
A Great Work on Addiction
Drug addiction has gotten a lot more attention these days as the image of victims has morphed from inner city homeless people to grandmothers who have had trouble weaning themselves off of post-operative medication. This book is enlightening for those who have not known an addict. Judith Grisel is the perfect author to write this book: a neuroscientist with a decade of personal addiction.
She frames the problem in stark terms: a) 16% of Americans over the age of twelve have an addiction problem b) a quarter of deaths are attributable to drugs c) drug treatment consumes a tenth of all healthcare spending (or twice as much as what we spend on cancer) d) there has been little improvement in treatment e) and only 10% of intervention is successful.
The main culprits that lead to the disease are having a genetic predisposition, exposure (and even worse from puberty to adulthood), and a catalyzing environment. The genetic component is interesting as she uses the example that Asians who get flush are less likely to be alcoholics and smokers who tend to absorb more nicotine smoke less.
Grisel explores different classes of drugs and what you find is the common thread that there is no gain without a later, equal loss. As far back as Socrates, this interplay of pleasure and pain has been well known. For each high, you pay it back with low or as the Grateful Dead put it, "Too much is never enough."
She imparts such interesting facts such as:
- Valium in the 1970's was used by one in five women and sent more people to the hospital than all other illicit drugs
- The doctors who discovered barbiturates died of overdoses themselves
- In 2010, the of alcohol (in poor health, drunk driving, crime) was 249 billion
- Kat production uses up 40% of Yemen's water supply
- Since ecstasy, unlike cocaine, effects transporters and not receptors, addicts are never the same regardless of how long they have been clean
Paraphrasing Grisel in her summation of the range of drugs: Alcohol and downers are negatively reinforcing because they reduce anxiety, Opiates reduce suffering, Stimulants reduce boredom. People tend to abuse those drugs that compliment themselves (such as the anxious who prefer alcohol) but also someone who is nervous who drinks to self medicate will become nervous.
I wish there was an optimistic conclusion but by the end of reading this I was worried that my own daily coffee habit had impaired my natural ability to awaken. Dependence is hard to overcome. Grisel recounts the story of her sharing a crack pipe with a toothless, homeless person who was deluded into thinking he was on top of the world. Ultimately, it was not jail or seeing her friends dying but rather her reconnection with her father that led to her recovery. She herself advises decreasing the drug's dosage, supplying palliative medicine for the inevitable withdrawal, and creating a support network. She points out that addicts naturally posses what are typically beneficial traits, like being heterodox, strong-willed and persistent. These traits certainly are apparent in this excellent scientist's work.
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12 people found this helpful
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- Randall Allen
- 03-20-19
Up-to-date and informative
The story is amazing but true. Some of the terminology I struggled with but the basic idea she gets across through many examples. It is amazing this girl is alive but it's incredible that she survived and secured a PhD
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3 people found this helpful
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- Mads
- 08-30-20
Good and informative
I really enjoyed hearing the author’s story. The book was also very informative, I’m glad I listened because there was so much interesting stuff. A lot of the neuro info went over my head though but the readers voice was very relaxing so I didn’t mind the moments of confusion.
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- Candice Merrick
- 03-21-19
homerun
fully loaded with information about most of the questions I have been wondering about. I am reading it for the second time.
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2 people found this helpful
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- R. MCRACKAN
- 09-13-19
Great research into an uncomfortable topic
Never Enough outlines the mechanics and dangers of the most common drugs. Despite the fact that this book very much should have used a narrator other than the author, it's a worthwhile listen which I highly recommend. I especially appreciated her analysis of pot, showing that while it's not the devil plant of early propaganda, it's also far from being benign or harmless.
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- Valerie Dudley
- 11-25-19
Very worthwhile and comprehensive book, from chocolate to heroin
This book is informative and interesting especially to a fellow addict. It does a good job of examining practical questions and giving in-depth answers that acknowledge a lack of certainty, I appreciated the complexity and lack of pigeon holing in the author’s conclusions. Her personal experience added a lot to the book, I could relate to her way of seeing addiction and why we do what we do.
Objectively researched and presented but put in a personal perspective that was effective. I liked it and want to listen to it again to ponder it some more. The ending conclusions clarified and elaborated on how I tend to view addiction.
A professional narrator may have been a better choice for audio version or some coaching on making it less low energy voice.
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- damien sheppard
- 06-17-19
informative and gripping
My eyes were opened to the ways in which the brain can be so resilient and at the same time so vulnerable. And in the same way I was amazed to realize how those prone to addiction can be exactly those most capable of bravery. Solving addiction is not just about curing those who are sick but about overcoming the isolation that makes all modern humans feel empty.
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4 people found this helpful