Showing titles in History & Commentary

The "absorbing and powerful" (Wall Street Journal) story of two pioneering suffragette doctors who shattered social expectations and transformed modern medicine during World War I. In No Man's Land, Wendy Moore illuminates this turbulent moment of global war and pandemic when women were, for the first time, allowed to operate on men. Their fortitude and brilliance serve as powerful reminders of what women can achieve against all odds.

For two thousand years, cadavers have been involved in science's boldest strides and weirdest undertakings. They've tested France's first guillotines, ridden the NASA Space Shuttle, been crucified in a Parisian laboratory to test the authenticity of the Shroud of Turin, and helped solve the mystery of TWA Flight 800. For every new surgical procedure, from heart transplants to gender reassignment surgery, cadavers have been there alongside surgeons, making history in their quiet way.

Salk became a cultural hero and icon for a whole generation. Now, at the fiftieth anniversary of the first national vaccination program, and as humanity is tantalizingly close to eradicating polio worldwide, comes this unforgettable chronicle. Salk's work was an unparalleled achievement, and it makes for a magnificent listen.

As America’s favorite frontline Covid-19 health journalist, Dr. Sanjay Gupta has barely left his primetime seat in his makeshift studio basement since the pandemic began (other than to perform brain surgery). He’s had insider access to the drama’s unfolding, including exclusive conversations with the world’s top public health experts and behind-the-scenes scientists racing to find treatments and cures.

Shooting Up: A Short History of Drugs and War examines how intoxicants have been put to the service of states, empires, and their armies throughout history. Since the beginning of organized combat, armed forces have prescribed drugs to their members for two general purposes: to enhance performance during combat and to counter the trauma of killing and witnessing violence after it is over.

In 1959, a Cincinnati pharmaceutical firm, the William S. Merrell Company, quietly began distributing samples of an exciting new wonder drug already popular around the world. Touted as a sedative without risks, thalidomide was handed out freely, under the guise of clinical trials, by doctors who believed approval by the Food and Drug Administration was imminent. But in 1960, when the application for thalidomide landed on the desk of FDA medical reviewer Frances Kelsey, she quickly grew suspicious.

Today, astonishing surgical breakthroughs are making limb transplants, face transplants, and a host of other previously undreamed-of operations possible. But getting here has not been a simple story of medical progress. In Blood and Guts, veteran science writer Richard Hollingham weaves a compelling narrative from the key moments in surgical history. We have a ringside seat in the operating theater of University College Hospital in London as world-renowned Victorian surgeon Robert Liston performs a remarkable amputation in 30 seconds - from first cut to final stitch.

In 1932, the US Public Health Service recruited 623 African American men from Macon County, Alabama, for a study of "the effects of untreated syphilis in the Negro male". For the next 40 years - even after the development of penicillin, the cure for syphilis - these men were denied medical care for this potentially fatal disease.

This amazing tale is the story of one of America's oldest and most unusual urban hospitals. From it's inception as a "Poor House" dispensing free medical care to indigents, Chicago's Cook County Hospital has been both a renowned teaching hospital and the healthcare provider of last resort for the city's uninsured. County covers more than thirty years of its history, beginning in the late 1970s when the author began his internship, to the "Final Rounds" when the enormous iconic Victorian hospital building was replaced and hundreds of former trainees gathered to bid it an emotional farewell.

Food and Drug Administration approval for COVID-19 vaccines and the controversial Alzheimer's drug Aduhelm made headlines, but few of us know much about how the agency does its work. Why is the FDA the ultimate United States authority on a drug's safety and efficacy? In Drugs and the FDA, Mikkael Sekeres—a leading oncologist and former chair of the FDA's cancer drug advisory committee—tells the story of how the FDA became the most trusted regulatory agency in the world.

A century ago, sleep was considered a state of nothingness—even a primitive habit that we could learn to overcome. Then, an immigrant scientist and his assistant spent a month in the depths of a Kentucky cave, making nationwide headlines and thrusting sleep science to the forefront of our consciousness. Award-winning journalist Kenneth Miller weaves together science and history to tell the story of four outsider scientists who took sleep science from fringe discipline to mainstream obsession through spectacular experiments, technological innovation, and single-minded commitment.

Galen of Pergamum (A.D. 129-ca. 216) began his remarkable career tending to wounded gladiators in provincial Asia Minor. Later in life he achieved great distinction as one of a small circle of court physicians to the family of Emperor Marcus Aurelius, at the very heart of Roman society. Susan Mattern's The Prince of Medicine offers the first authoritative biography in English of this brilliant, audacious, and profoundly influential figure.

A good book may have the power to change the way we see the world, but a great book actually becomes part of our daily consciousness, pervading our thinking to the point that we take it for granted, and we forget how provocative and challenging its ideas once were - and still are. The Structure of Scientific Revolutions is that kind of book.

Today, 90 percent of psychiatric beds are located in jails and prisons across the United States, institutions that confine disproportionate numbers of African Americans. After more than a decade of research, the celebrated scholar and activist Mab Segrest locates the deep historical roots of this startling fact, turning her sights on a long-forgotten cauldron of racial ideology: the state mental asylum system in which psychiatry was born and whose influences extend into our troubled present.

Following the trail of an unexpected family connection, acclaimed journalist Pam Fessler has unearthed the lost world of the patients, nurses, doctors, and researchers at Carville who struggled for over a century to eradicate Hansen's disease, the modern name for leprosy. Amid widespread public anxiety about foreign contamination and contagion, patients were deprived of basic rights - denied the right to vote, restricted from leaving Carville, and often forbidden from contact with their own parents or children.

One in ten American adults tried intermittent fasting last year, and they may be on to something. The latest research shows that fasting repairs cellular damage, improves the outcomes for chemotherapy patients, and helps with keeping a healthy weight, leading to a resurgence in recent years. Journalist Steve Hendricks’s The Oldest Cure in the World tells the history of fasting—from the ancient world (Jesus treated an epileptic with fasting) to its rediscovery centuries later.

In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.

Medicine has become inhuman, to disastrous effect. The doctor-patient relationship - the heart of medicine - is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality.

After his father died, James L. Nolan, Jr., took possession of a box of private family materials. To his surprise, the small secret archive contained a treasure trove of information about his grandfather's role as a doctor in the Manhattan Project. Dr. Nolan, it turned out, had been a significant figure.

The Revolutionary War broke out during a smallpox epidemic, and in response, General George Washington ordered the inoculation of the Continental Army. But Washington did not have to convince fearful colonists to protect themselves against smallpox. In The Contagion of Liberty, Andrew M. Wehrman describes a revolution within a revolution, where the violent insistence for freedom from disease ultimately helped American colonists achieve independence from Great Britain.