
Ravenous
Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection
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Narrated by:
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Mark Bramhall
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By:
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Sam Apple
About this listen
The extraordinary story of the Nazi-era scientific genius who discovered how cancer cells eat - and what it means for how we should.
The Nobel laureate Otto Warburg - a cousin of the famous finance Warburgs - was widely regarded in his day as one of the most important biochemists of the 20th century, a man whose research was integral to humanity’s understanding of cancer. He was also among the most despised figures in Nazi Germany. As a Jewish homosexual living openly with his male partner, Warburg represented all that the Third Reich abhorred. Yet Hitler and his top advisors dreaded cancer, and protected Warburg in the hope that he could cure it.
In Ravenous, Sam Apple reclaims Otto Warburg as a forgotten, morally compromised genius who pursued cancer single-mindedly even as Europe disintegrated around him. While the vast majority of Jewish scientists fled Germany in the anxious years leading up to World War II, Warburg remained in Berlin, working under the watchful eye of the dictatorship. With the Nazis goose-stepping their way across Europe, systematically rounding up and murdering millions of Jews, Warburg awoke each morning in an elegant, antiques-filled home and rode horses with his partner, Jacob Heiss, before delving into his research at the Kaiser Wilhelm Society.
Hitler and other Nazi leaders, Apple shows, were deeply troubled by skyrocketing cancer rates across the Western world, viewing cancer as an existential threat akin to Judaism or homosexuality. Ironically, they viewed Warburg as Germany’s best chance of survival. Setting Warburg’s work against an absorbing history of cancer science, Apple follows him as he arrives at his central belief that cancer is a problem of metabolism. Though Warburg’s metabolic approach to cancer was considered groundbreaking, his work was soon eclipsed in the early postwar era, after the discovery of the structure of DNA set off a search for the genetic origins of cancer.
Remarkably, Warburg’s theory has undergone a resurgence in our own time, as scientists have begun to investigate the dangers of sugar and the link between obesity and cancer, finding that the way we eat can influence how cancer cells take up nutrients and grow. Rooting his revelations in extensive archival research as well as dozens of interviews with today’s leading cancer authorities, Apple demonstrates how Warburg’s midcentury work may well hold the secret to why cancer became so common in the modern world and how we can reverse the trend. A tale of scientific discovery, personal peril, and the race to end a disastrous disease, Ravenous would be the stuff of the most inventive fiction were it not, in fact, true.
©2021 Sam Apple (P)2021 Random House AudioListeners also enjoyed...
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Critic reviews
"Eye-opening...filled with...outrageous and entertaining stories.... I walked away from Ravenous thinking of Otto Warburg as a sort of Sigmund Freud of cancer research." (Sam Kean, Wall Street Journal)
"[Apple] weaves together this complex narrative in a way that makes arcane science accessible and fascinating. The book is also thought-provoking for anyone interested in avoiding cancer - and who isn’t?" (Marie McCullough, Philadelphia Inquirer)
"The research that Warburg is best known for today, and the work that forms the backbone of Ravenous, is his discovery that cancer cells behave differently from healthy cells in two very specific ways: They consume massive amounts of glucose — Apple compares them to ravenous shipwrecked sailors — and they eschew aerobic respiration in favor of fermentation.... Apple covers everything from Hitler’s obsessive preoccupation with cancer to how the German Empire’s transformation into an industrial powerhouse led to a Romanticism-fueled movement that emphasized both environmental and racial purity. The fact that Apple can make these stories...feel so immediate is a testament to his canny knack for choosing apposite details." (New York Times Book Review)
"A long-overdue biography of German biologist Otto Warburg (1883-1970), who won the Nobel Prize for his work on cell respiration and metabolism, especially as related to cancer.... A welcome addition to the library on the disease and one of its most successful enemies." (Kirkus Reviews)
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What You Have Heard is True is a devastating, lyrical, and visionary memoir about a young woman’s brave choice to engage with horror in order to help others. Written by one of the most gifted poets of her generation, this is the story of a woman’s radical act of empathy, and her fateful encounter with an intriguing man who changes the course of her life.
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Beautiful story
- By Norhilda on 05-09-19
By: Carolyn Forché
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Fire and Brimstone
- The North Butte Mining Disaster of 1917
- By: Michael Punke
- Narrated by: Christopher Grove
- Length: 9 hrs and 16 mins
- Unabridged
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The worst hard-rock mining disaster in American history began a half hour before midnight on June 8, 1917, when fire broke out in the North Butte Mining Company's Granite Mountain shaft. Sparked more than 2,000 feet below ground, the fire spewed flames, smoke, and poisonous gas through a labyrinth of underground tunnels. Within an hour more than 400 men would be locked in a battle to survive. Within three days 164 of them would be dead.
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Fairly Solid Book With Good History
- By Matthew on 08-18-16
By: Michael Punke
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Money for Nothing
- The Scientists, Fraudsters, and Corrupt Politicians Who Reinvented Money, Panicked a Nation, and Made the World Rich
- By: Thomas Levenson
- Narrated by: Dan Bittner
- Length: 12 hrs and 12 mins
- Unabridged
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In the heart of the Scientific Revolution, when new theories promised to explain the affairs of the universe, Britain was broke, facing a mountain of debt accumulated in war after war it could not afford. But that same Scientific Revolution - the kind of thinking that helped Isaac Newton solve the mysteries of the cosmos - would soon lead clever, if not always scrupulous, men to try to figure a way out of Britain’s financial troubles.
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Financial innovation's first song of the siren.
- By Michael Barnett on 09-06-20
By: Thomas Levenson
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Time's Echo
- The Second World War, the Holocaust, and the Music of Remembrance
- By: Jeremy Eichler
- Narrated by: Jeremy Eichler, Sherrill Milnes
- Length: 11 hrs and 5 mins
- Unabridged
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In 1785, when the great German poet Friedrich Schiller penned his immortal “Ode to Joy,” he crystallized the deepest hopes and dreams of the European Enlightenment for a new era of peace and freedom, a time when millions would be embraced as equals. Beethoven’s Ninth Symphony then gave wing to Schiller’s words, but barely a century later these same words were claimed by Nazi propagandists and twisted by a barbarism so complete that it ruptured, as one philosopher put it, “the deep layer of solidarity among all who wear a human face.”
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marvelous storytelling
- By Anonymous User on 01-08-25
By: Jeremy Eichler
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Atomic Spy
- The Dark Lives of Klaus Fuchs
- By: Nancy Thorndike Greenspan
- Narrated by: Tavia Gilbert
- Length: 12 hrs and 34 mins
- Unabridged
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German by birth, British by naturalization, Communist by conviction, Klaus Fuchs was a fearless Nazi resister, a brilliant scientist, and an infamous spy. He was convicted of espionage by Britain in 1950 for handing over the designs of the plutonium bomb to the Russians and has gone down in history as one of the most dangerous agents in American and British history. He put an end to America's nuclear hegemony and single-handedly heated up the Cold War. But, was Klaus Fuchs really evil?
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Morally revolting -- a player in mass murder cast as a saint
- By anonymous on 11-24-20
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Aftermath
- Life in the Fallout of the Third Reich, 1945-1955
- By: Harald Jähner, Shaun Whiteside - translator
- Narrated by: Rob Shapiro
- Length: 12 hrs and 36 mins
- Unabridged
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How does a nation recover from fascism and turn toward a free society once more? This internationally acclaimed revelatory history of the transformational decade that followed World War II illustrates how Germany raised itself out of the ashes of defeat and reckoned with the corruption of its soul and the horrors of the Holocaust - and features over 40 eye-opening black-and-white photographs and posters from the period.
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Where are the photos?
- By Cassandra on 01-17-22
By: Harald Jähner, and others
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The Walls Have Ears
- The Greatest Intelligence Operation of World War II
- By: Helen Fry
- Narrated by: Jean Gilpin
- Length: 11 hrs and 41 mins
- Unabridged
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At the outbreak of World War II, MI6 spymaster Thomas Kendrick arrived at the Tower of London to set up a top secret operation: German prisoners' cells were to be bugged and listeners installed behind the walls to record and transcribe their private conversations. This mission proved so effective that it would go on to be set up at three further sites - and provide the Allies with crucial insight into new technology being developed by the Nazis. In this astonishing history, Helen Fry uncovers the inner workings of the bugging operation.
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inresting look into a secret world.
- By Christopher Daniels on 05-22-20
By: Helen Fry
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Hotel Scarface
- Where Cocaine Cowboys Partied and Plotted to Control Miami
- By: Roben Farzad
- Narrated by: Jonathan Davis
- Length: 9 hrs and 18 mins
- Unabridged
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The wild, true story of the Mutiny, the hotel and club that embodied the decadence of Miami's cocaine cowboys heyday - and an inspiration for the blockbuster film Scarface.
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Ehh...
- By Nick on 11-17-17
By: Roben Farzad
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Hidden in Plain View
- A Secret Story of Quilts and the Underground Railroad
- By: Jacqueline L. Tobin, Raymond G. Dobard, Cuesta Benberry, and others
- Narrated by: Janina Edwards, Leon Nixon
- Length: 5 hrs and 33 mins
- Unabridged
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In 1993, Jacqueline Tobin visited the Old Market Building in the historic district of Charleston, South Carolina, where craftspeople sell their wares. Amid piles of beautiful handmade quilts, Tobin met African American quilter Ozella Williams and the two struck up a conversation. With the admonition to "write this down," Williams began to tell a fascinating story that had been handed down from her mother and grandmother before her. As Tobin sat in rapt attention, Williams began to describe how slaves made coded quilts and then used them to navigate their escape on the Underground Railroad.
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Wonderful listen.
- By Jane Wolfe on 11-27-24
By: Jacqueline L. Tobin, and others
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Last Witnesses
- An Oral History of the Children of World War II
- By: Svetlana Alexievich, Richard Pevear, Larissa Volokhonsky
- Narrated by: Julia Emelin, Allen Lewis Rickman
- Length: 9 hrs and 57 mins
- Unabridged
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Bringing together dozens of voices in her distinctive style, Last Witnesses is Alexievich’s collection of the memories of those who were children during World War II. They had sometimes been soldiers as well as witnesses, and their generation grew up with the trauma of the war deeply embedded - a trauma that would change the course of the Russian nation. Collectively, this symphony of children’s stories, filled with the everyday details of life in combat, reveals an altogether unprecedented view of the war.
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And how many years to forget?
- By Darwin8u on 09-16-21
By: Svetlana Alexievich, and others
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Enemy of All Mankind
- A True Story of Piracy, Power, and History's First Global Manhunt
- By: Steven Johnson
- Narrated by: Jason Culp
- Length: 8 hrs and 14 mins
- Unabridged
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Henry Every was the 17th century’s most notorious pirate. The press published wildly popular - and wildly inaccurate - reports of his nefarious adventures. The British government offered enormous bounties for his capture, alive or (preferably) dead. But Steven Johnson argues that Every’s most lasting legacy was his inadvertent triggering of a major shift in the global economy. Enemy of All Mankind focuses on one key event - the attack on an Indian treasure ship by Every and his crew - and its surprising repercussions across time and space.
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Slow
- By Gary V Howell on 06-07-20
By: Steven Johnson
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I Want You to Know We're Still Here
- A Post-Holocaust Memoir
- By: Esther Safran Foer
- Narrated by: Ellen Archer, Esther Safran Foer
- Length: 6 hrs and 15 mins
- Unabridged
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Esther Safran Foer grew up in a home where the past was too terrible to speak of. The child of parents who were each the sole survivors of their respective families, for Esther the Holocaust loomed in the backdrop of daily life, felt but never discussed. The result was a childhood marked by painful silences and continued tragedy. Even as she built a successful career, married, and raised three children, Esther always felt herself searching.
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Interesting but…
- By mk on 08-23-21
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Nuking the Moon
- And Other Intelligence Schemes and Military Plots Left on the Drawing Board
- By: Vince Houghton
- Narrated by: Vince Houghton
- Length: 8 hrs and 29 mins
- Unabridged
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In 1958, the US Air Force nuked the moon as a show of military force. In 1967, the CIA sent live cats to spy on the Soviet government. In 1942, the British built a torpedo-proof aircraft carrier out of an iceberg. Of course, none of these things ever actually happened. But in Nuking the Moon, intelligence historian Vince Houghton proves that abandoned plans can be just as illuminating - and every bit as entertaining - as the ones that made it.
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Manchild writes book filled with his opinion
- By Just One More Opinion On The Internet on 08-31-19
By: Vince Houghton
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On All Fronts
- The Education of a Journalist
- By: Clarissa Ward
- Narrated by: Clarissa Ward
- Length: 9 hrs and 38 mins
- Unabridged
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Clarissa Ward is a world-renowned conflict reporter. In this strange age of crisis where there really is no front line, she has moved from one hot zone to the next. With multiple assignments in Syria, Egypt, and Afghanistan, Ward, who speaks seven languages, has been based in Baghdad, Beirut, Beijing, and Moscow. She has seen and documented the violent remaking of the world at close range. With her deep empathy, Ward finds a way to tell the hardest stories. On All Fronts is the riveting account of Ward’s singular career and of journalism in this age of extremism.
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Insights gained!
- By J. Harry on 11-10-20
By: Clarissa Ward
What listeners say about Ravenous
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- Repair Bear
- 11-20-21
Great Story
Anyone interested in the history of cancer research should really enjoy this. I found it fascinating.
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1 person found this helpful
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- Afsaneh
- 04-03-23
Very rich content
Enjoyed listening to this audiobook. Very well performed. Many times had to go back and re-listen over and over to understand a bit the scientific content.
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- tony
- 04-13-23
Excellent book
This book is making a heavy topic an easy listen. Not only does it summarize tons of relevant research both historic and modern, but it links together research and researchers across time and space in a most satisfying way.
I highly recommend this book.
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1 person found this helpful
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- Garry
- 09-29-23
An enlightening biography
I might even go back to the last couple chapters to see if missed anything, truly entertaining.
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- Leila M
- 07-04-24
Excellent
A fascinating account of World War II, Germans, Nazis, and cancer science. Mr. Apple is gifted at explaining complicated concepts of science in a simplified way. He even follows cancer research up to modern times. Highly recommend.
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- Joerg
- 06-10-21
Highly recommended, a must read.
The book gives a unique insight into the life and work of scientist Otto Warbug, his genius, his struggles during the Nazi regime as a “Mischling”, being of Jewish and Protestant descent.
This real life story includes many captivating dialogues that make readers feel like they are immersed in the actual events of the time. These include not just Otto Warburg, but co-workers and other individuals. Also Hitler and other adversaries of the era. The legacy of Otto Warburg and his cancer research was only fairly recently rediscovered, finally proving Warburg’s hypothesis, now dubbed The Warburg Effect. Warburg’s ideas are now the foundation to further explore cancer treatment.
My English is probably not good enough to give this book the credit it deserves. So I will conclude that I truly enjoyed the book, not only for the content, but the writing style as well.
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7 people found this helpful
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- Lorrie Pratley
- 06-02-22
A Fantastically Relevant Read
What I thought I was getting was a retrospective on the life of one of humanity's great scientists. In that regard, "Ravenous" did not disappoint. However, the book also takes the reader through the history of cancer research until it lands on the modern understanding of the disease and, most importantly, all but screams the importance of diet in the process. A great read for those interested in historical biographies. A fantastic read if one is also interested in the diet connection to cancer. It is quite likely I will return to this book for its insights.
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1 person found this helpful
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- Bmt
- 08-09-21
Outstanding!
Outstanding! Entertaining as it is informing. Absolutely superb story telling and extremely illuminating. Well done!
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- Amazon Customer
- 02-08-24
Interesting read on many levels
Well written and with so much going on for one book. There’s the gay Jewish angle - of a famous scientist living and working in Nazi Germany. There’s Hitler’s fear of cancer and, in the end, his ironic addiction to exactly the wrong foods. There is the life of a scientist and their works - the way some important findings can be ignored, forgotten, and rediscovered. I was so engrossed that I finished the book in two days.
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- Tracy
- 01-31-25
A reminder of truths we once knew, but with a little time and good marketing, were swept under the rug and forgotten.
This book needs to be read by everyone interested in cancer research or even just interested in avoiding cancer in the first place. It's well researched, written and narrated. This history isn't far in the past, but is just as relevant now as ever.
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