A masterful synchronization of history and cutting-edge science shines new light on humanity's darkest diagnosis. In the wake of the Cancer Genome Atlas project's failure to provide a legible road map to a cure for cancer, science writer Travis Christofferson illuminates a promising blend of old and new perspectives on the disease.

In Ketones: The Fourth Fuel, science writer Travis Christofferson weaves a fascinating narrative of humanity's quest to understand how our bodies produce energy - transporting us on a scientific expedition from the past to the present - across early modern Europe to modern laboratories spanning the globe. The listener is taken on a riveting and revelatory journey that follows Nobel Prize-winning scientists from the 19th and 20th centuries as they map the pathways and cycles that comprise human metabolism.

Almost every day we are bombarded with the seemingly incontrovertible message that we must reduce our consumption of meat and dairy—or eliminate them from our diets altogether. But what if the pervasive message that the plant-based diet will improve our health and save the planet is misleading—or even false? What if removing animal foods from our diet is a serious threat to human health, and a red herring in the fight against climate change.

This is a 150-year detective story with a cast of unrecognized heroes who may, finally, become known for their work on the true causes of heart disease. Exploring the truth about cholesterol—the apparently tried, and convicted, cause of millions of deaths from heart disease—with billions spent each year on lowering cholesterol with diet and drugs.

Nature puts a “survival switch” in our bodies to protect us from starvation. Stuck in the “on” position, it’s the hidden source of weight gain, heart disease, and many other common health struggles. But you can turn it off.

The New York Times best-selling author of Fat Chance explains the eight pathologies that underlie all chronic disease, documents how processed food has impacted them to ruin our health, economy, and environment over the past 50 years, and proposes an urgent manifesto and strategy to cure both us and the planet.

Our understanding of cancer is slowly undergoing a revolution, allowing for the development of more effective treatments. For the first time ever, the death rate from cancer is showing a steady decline...but the “War on Cancer” has hardly been won. In The Cancer Code, Dr. Jason Fung offers a revolutionary new understanding of this invasive, often fatal disease - what it is, how it manifests, and why it is so challenging to treat.

We are in the midst of a global mental health crisis, and mental illnesses are on the rise. But what causes mental illness? And why are mental health problems so hard to treat? Drawing on decades of research, Harvard psychiatrist Dr. Chris Palmer outlines a revolutionary new understanding that for the first time unites our existing knowledge about mental illness within a single framework: mental disorders are metabolic disorders of the brain. Brain Energy will transform the field of mental health, and the lives of countless people around the world.

The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction, and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third.

For decades we have been taught that fat is bad for us, carbohydrates better, and that the key to a healthy weight is eating less and exercising more. Yet despite this advice, we have seen unprecedented epidemics of obesity and diabetes. Taubes argues that the problem lies in refined carbohydrates, like white flour, easily digested starches, and sugars, and that the key to good health is the kind of calories we take in, not the number.

From an acclaimed Harvard professor and one of Time’s most influential people, this paradigm-shifting audiobook shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls listeners to consider a future where aging can be treated.

Since the beginning of the 20th century, cancer rates have increased exponentially - now affecting almost 50 percent of the American population. Conventional treatment continues to rely on chemotherapy, surgery, and radiation to attack cancer cells. Yet research has repeatedly shown that 95 percent of cancer cases are directly linked to diet and lifestyle. The Metabolic Approach to Cancer is the audiobook we have been waiting for - it offers an innovative, metabolic-focused nutrition protocol that actually works.

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells - taken without her knowledge - became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than 60 years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects.

In Fantasy Island, Ed Morales traces how, over the years, Puerto Rico has served as a colonial satellite, a Cold War Caribbean showcase, a dumping ground for US manufactured goods, and a corporate tax shelter. He also shows how it has become a blank canvas for mercenary experiments in disaster capitalism on the frontlines of climate change, hamstrung by internal political corruption and the US federal government's prioritization of outside financial interests.

So begins this suspenseful, impeccably researched history that draws on new access to diaries to tell the story of three men who were intimately involved with America’s decision to drop the atomic bomb—and Japan’s decision to surrender. They are Henry Stimson, the American Secretary of War, who oversaw J. Robert Oppenheimer under the Manhattan Project; Gen. Carl “Tooey” Spaatz, head of strategic bombing in the Pacific, who supervised the planes that dropped the bombs; and Japanese Foreign Minister Shigenori Togo.

After the terrorist attacks of 9/11 destroyed the World Trade Center, New Yorkers and Americans faced a critical set of questions: What should be done with the site? Could the towers be replaced? And how best to memorialize those lost on that day? For Larry Silverstein, a lifelong New Yorker who had signed a lease for the properties just a few months before the attacks, the answer was clear: America had to rebuild as quickly as possible.

What do we owe the past? How to make peace with a dark family history? Burkhard Bilger hardly knew his grandfather growing up. His parents immigrated to Oklahoma from Germany after World War II, and though his mother was an historian, she rarely talked about her father or what he did during the war. Then one day a packet of letters arrived from Germany, yellowing with age, and a secret history began to unfold.

What You Have Heard is True is a devastating, lyrical, and visionary memoir about a young woman’s brave choice to engage with horror in order to help others. Written by one of the most gifted poets of her generation, this is the story of a woman’s radical act of empathy, and her fateful encounter with an intriguing man who changes the course of her life.

The worst hard-rock mining disaster in American history began a half hour before midnight on June 8, 1917, when fire broke out in the North Butte Mining Company's Granite Mountain shaft. Sparked more than 2,000 feet below ground, the fire spewed flames, smoke, and poisonous gas through a labyrinth of underground tunnels. Within an hour more than 400 men would be locked in a battle to survive. Within three days 164 of them would be dead.

In the heart of the Scientific Revolution, when new theories promised to explain the affairs of the universe, Britain was broke, facing a mountain of debt accumulated in war after war it could not afford. But that same Scientific Revolution - the kind of thinking that helped Isaac Newton solve the mysteries of the cosmos - would soon lead clever, if not always scrupulous, men to try to figure a way out of Britain’s financial troubles.

How does a nation recover from fascism and turn toward a free society once more? This internationally acclaimed revelatory history of the transformational decade that followed World War II illustrates how Germany raised itself out of the ashes of defeat and reckoned with the corruption of its soul and the horrors of the Holocaust - and features over 40 eye-opening black-and-white photographs and posters from the period.

German by birth, British by naturalization, Communist by conviction, Klaus Fuchs was a fearless Nazi resister, a brilliant scientist, and an infamous spy. He was convicted of espionage by Britain in 1950 for handing over the designs of the plutonium bomb to the Russians and has gone down in history as one of the most dangerous agents in American and British history. He put an end to America's nuclear hegemony and single-handedly heated up the Cold War. But, was Klaus Fuchs really evil?

At the outbreak of World War II, MI6 spymaster Thomas Kendrick arrived at the Tower of London to set up a top secret operation: German prisoners' cells were to be bugged and listeners installed behind the walls to record and transcribe their private conversations. This mission proved so effective that it would go on to be set up at three further sites - and provide the Allies with crucial insight into new technology being developed by the Nazis. In this astonishing history, Helen Fry uncovers the inner workings of the bugging operation.

Clarissa Ward is a world-renowned conflict reporter. In this strange age of crisis where there really is no front line, she has moved from one hot zone to the next. With multiple assignments in Syria, Egypt, and Afghanistan, Ward, who speaks seven languages, has been based in Baghdad, Beirut, Beijing, and Moscow. She has seen and documented the violent remaking of the world at close range. With her deep empathy, Ward finds a way to tell the hardest stories. On All Fronts is the riveting account of Ward’s singular career and of journalism in this age of extremism.

In 1993, Jacqueline Tobin visited the Old Market Building in the historic district of Charleston, South Carolina, where craftspeople sell their wares. Amid piles of beautiful handmade quilts, Tobin met African American quilter Ozella Williams and the two struck up a conversation. With the admonition to "write this down," Williams began to tell a fascinating story that had been handed down from her mother and grandmother before her. As Tobin sat in rapt attention, Williams began to describe how slaves made coded quilts and then used them to navigate their escape on the Underground Railroad.

In 1958, the US Air Force nuked the moon as a show of military force. In 1967, the CIA sent live cats to spy on the Soviet government. In 1942, the British built a torpedo-proof aircraft carrier out of an iceberg. Of course, none of these things ever actually happened. But in Nuking the Moon, intelligence historian Vince Houghton proves that abandoned plans can be just as illuminating - and every bit as entertaining - as the ones that made it.

Bringing together dozens of voices in her distinctive style, Last Witnesses is Alexievich’s collection of the memories of those who were children during World War II. They had sometimes been soldiers as well as witnesses, and their generation grew up with the trauma of the war deeply embedded - a trauma that would change the course of the Russian nation. Collectively, this symphony of children’s stories, filled with the everyday details of life in combat, reveals an altogether unprecedented view of the war.

Henry Every was the 17th century’s most notorious pirate. The press published wildly popular - and wildly inaccurate - reports of his nefarious adventures. The British government offered enormous bounties for his capture, alive or (preferably) dead. But Steven Johnson argues that Every’s most lasting legacy was his inadvertent triggering of a major shift in the global economy. Enemy of All Mankind focuses on one key event - the attack on an Indian treasure ship by Every and his crew - and its surprising repercussions across time and space.